Rothenberger, Aribert

[["dc.bibliographiccitation.firstpage","153"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","European Child & Adolescent Psychiatry"],["dc.bibliographiccitation.lastpage","154"],["dc.bibliographiccitation.volume","20"],["dc.contributor.author","Roessner, Veit"],["dc.contributor.author","Rothenberger, Aribert"],["dc.contributor.author","Rickards, Hugh"],["dc.contributor.author","Hoekstra, Pieter J."],["dc.date.accessioned","2018-11-07T08:57:31Z"],["dc.date.available","2018-11-07T08:57:31Z"],["dc.date.issued","2011"],["dc.identifier.doi","10.1007/s00787-011-0165-5"],["dc.identifier.isi","000288903000001"],["dc.identifier.pmid","21445722"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/7337"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/23418"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","1018-8827"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","European clinical guidelines for Tourette Syndrome and other tic disorders"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.subtype","letter_note"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1183"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Neuroscience"],["dc.bibliographiccitation.lastpage","1191"],["dc.bibliographiccitation.volume","167"],["dc.contributor.author","Roessner, Veit"],["dc.contributor.author","Sagvolden, T."],["dc.contributor.author","DasBanerjee, T."],["dc.contributor.author","Middleton, Frank A."],["dc.contributor.author","Faraone, Steven V."],["dc.contributor.author","Walaas, S. I."],["dc.contributor.author","Becker, A."],["dc.contributor.author","Rothenberger, A."],["dc.contributor.author","Bock, Nathalie"],["dc.date.accessioned","2018-11-07T08:42:20Z"],["dc.date.available","2018-11-07T08:42:20Z"],["dc.date.issued","2010"],["dc.description.abstract","The spontaneously hypertensive rat (SHR/NCrI) is a validated model of attention-deficit/hyperactivity disorder (ADHD) combined subtype, whereas a recently identified sub-strain of the Wistar Kyoto rat (WKY/NCrI) is a model of ADHD inattentive subtype. In this study, we first examined the expression of genes involved in dopamine signaling and metabolism in the dorsal striatum and ventral mesencephalon of these two rat strains, as well as three reference control strains (WKY/NHsd, WK/HanTac, and SD/NTac) using quantitative real time RT-PCR. Next, striatal dopamine transporter (DAT) density was determined by ligand binding assay in the two ADHD-like strains at different developmental stages and after methylphenidate treatment. In adult rats, the mRNA expression of DAT and tyrosine hydroxylase was elevated in SHR/NCrI and WKY/NCrI rats compared to control strains, with differences between SHR/NCrI and WKY/NCrI rats also evident. During normal development, changes of striatal DAT densities occurred in both strains with lower densities in WKY/NCrI compared to SHR/NCrI after day 25. Two-weeks methylphenidate treatment during different developmental stages was associated with decreased striatal DAT density in both rat strains compared to the non-treated rats with more pronounced effects followed prepubertal treatment. These results suggest differences in the pathophysiology of the combined versus the predominantly inattentive animal model of ADHD. Finally, treatment with methylphenidate might reduce elevated DAT levels more effectively in the combined subtype especially when applied before puberty. (C) 2010 IBRO. Published by Elsevier Ltd. All rights reserved."],["dc.identifier.doi","10.1016/j.neuroscience.2010.02.073"],["dc.identifier.isi","000277434800022"],["dc.identifier.pmid","20211696"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6332"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/19675"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Pergamon-elsevier Science Ltd"],["dc.relation.issn","0306-4522"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","METHYLPHENIDATE NORMALIZES ELEVATED DOPAMINE TRANSPORTER DENSITIES IN AN ANIMAL MODEL OF THE ATTENTION-DEFICIT/HYPERACTIVITY DISORDER COMBINED TYPE, BUT NOT TO THE SAME EXTENT IN ONE OF THE ATTENTION-DEFICIT/HYPERACTIVITY DISORDER INATTENTIVE TYPE"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","53"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Psychopathology"],["dc.bibliographiccitation.lastpage","59"],["dc.bibliographiccitation.volume","44"],["dc.contributor.author","Holtmann, Martin"],["dc.contributor.author","Becker, Andreas"],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Rothenberger, Aribert"],["dc.contributor.author","Roessner, Veit"],["dc.date.accessioned","2018-11-07T09:01:59Z"],["dc.date.available","2018-11-07T09:01:59Z"],["dc.date.issued","2011"],["dc.description.abstract","Background: In many severely mentally disordered children, the clinical presentation is complicated by comorbid affective and behavioral dysregulation. Recently, a highly heritable behavioral phenotype of simultaneous deviance on the nanxious/depressed, attention problems, and aggressive behavior syndrome scales has been identified on the Child Behavior Checklist Dysregulation Profile (CBCL-DP). The aim of the present pilot study was to determine an equivalent to the CBCL-DP using the Strengths and Difficulties Questionnaire (SDQ). Sampling and Methods: We applied stepwise linear discriminant analyses and receiver operating characteristic (ROC) analysis to data from 543 consecutively referred children and adolescents, aged 5-17 years. The CBCL and the SDQ were completed by parents as part of the diagnostic routine. ICD-10 discharge diagnoses were established in consensus conferences. Results: A combination of five SDQ items (SDQ-Dysregulation Profile, SDQ-DP) yielded the best discrimination of children with and without CBCL-DP and classified 81.0% of the subjects correctly leading to an area under the curve of 0.93. The content of the five SDQ-DP items mirrors well the mixed behavioral phenotype of anxious-depressive, aggressive and attention problems captured by the CBCL-DP. SDQ-DP status was highly correlated with CBCL-DP status and was best defined by a SDQ-DP score >= 5. Conclusions: The psychometric properties of the SDQ-DP have been robustly tested and validated. Based on these results, clinicians may use the SDQ-DP as a useful and economical screening measure to improve the assessment, prevention, and treatment of severe dysregulation in childhood and adolescence. Future investigations should study the longitudinal stability, heritability, and genetic associations of this behavioral phenotype. Copyright (C) 2010 S. Karger AG, Basel"],["dc.identifier.doi","10.1159/000318164"],["dc.identifier.isi","000284157300008"],["dc.identifier.pmid","21072000"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/8050"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/24567"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Karger"],["dc.relation.issn","0254-4962"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Psychometric Validity of the Strengths and Difficulties Questionnaire-Dysregulation Profile"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","173"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","European Child & Adolescent Psychiatry"],["dc.bibliographiccitation.lastpage","196"],["dc.bibliographiccitation.volume","20"],["dc.contributor.author","Roessner, Veit"],["dc.contributor.author","Plessen, Kerstin J."],["dc.contributor.author","Rothenberger, Aribert"],["dc.contributor.author","Ludolph, Andrea G."],["dc.contributor.author","Rizzo, Renata"],["dc.contributor.author","Skov, Liselotte"],["dc.contributor.author","Strand, Gerd"],["dc.contributor.author","Stern, Jeremy S."],["dc.contributor.author","Termine, Cristiano"],["dc.contributor.author","Hoekstra, Pieter J."],["dc.date.accessioned","2018-11-07T08:57:31Z"],["dc.date.available","2018-11-07T08:57:31Z"],["dc.date.issued","2011"],["dc.description.abstract","To develop a European guideline on pharmacologic treatment of Tourette syndrome (TS) the available literature was thoroughly screened and extensively discussed by a working group of the European Society for the Study of Tourette syndrome (ESSTS). Although there are many more studies on pharmacotherapy of TS than on behavioral treatment options, only a limited number of studies meets rigorous quality criteria. Therefore, we have devised a two-stage approach. First, we present the highest level of evidence by reporting the findings of existing Cochrane reviews in this field. Subsequently, we provide the first comprehensive overview of all reports on pharmacological treatment options for TS through a MEDLINE, PubMed, and EMBASE search for all studies that document the effect of pharmacological treatment of TS and other tic disorders between 1970 and November 2010. We present a summary of the current consensus on pharmacological treatment options for TS in Europe to guide the clinician in daily practice. This summary is, however, rather a status quo of a clinically helpful but merely low evidence guideline, mainly driven by expert experience and opinion, since rigorous experimental studies are scarce."],["dc.identifier.doi","10.1007/s00787-011-0163-7"],["dc.identifier.isi","000288903000003"],["dc.identifier.pmid","21445724"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/7336"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/23419"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","1018-8827"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","European clinical guidelines for Tourette syndrome and other tic disorders. Part II: pharmacological treatment"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","1060"],["dc.bibliographiccitation.journal","Frontiers in Psychology"],["dc.bibliographiccitation.volume","7"],["dc.contributor.author","Roessner, Veit"],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Becker, Andreas"],["dc.contributor.author","Buse, Judith"],["dc.contributor.author","Wanderer, Sina"],["dc.contributor.author","Buitelaar, J. K."],["dc.contributor.author","Sergeant, Joseph A."],["dc.contributor.author","Sonuga-Barke, Edmund J."],["dc.contributor.author","Gill, Michael"],["dc.contributor.author","Manor, Iris"],["dc.contributor.author","Miranda, Ana"],["dc.contributor.author","Mulas, Fernando"],["dc.contributor.author","Oades, Robert D."],["dc.contributor.author","Roeyers, Herbert"],["dc.contributor.author","Steinhausen, Hans-Christoph"],["dc.contributor.author","Faraone, Steven V."],["dc.contributor.author","Asherson, Philip"],["dc.contributor.author","Rothenberger, Aribert"],["dc.date.accessioned","2018-11-07T10:11:32Z"],["dc.date.available","2018-11-07T10:11:32Z"],["dc.date.issued","2016"],["dc.description.abstract","Background: The association of attention-deficit/hyperactivity disorder (ADHD) and tic disorder (TD) is frequent and clinically important. Very few and inconclusive attempts have been made to clarify if and how the combination of ADHD-FTD runs in families. Aim: To determine the first time in a large-scale ADHD sample whether ADHD-FTD increases the risk of ADHDH+TD in siblings and, also the first time, if this is independent of their psychopathological vulnerability in general. Methods: The study is based on the International Multicenter ADHD Genetics (IMAGE) study. The present sub-sample of 2815 individuals included ADHD-index patients with co-existing TD (ADHD-FTD, n = 262) and without TD (ADHD+TD, n = 947) as well as their 1606 full siblings (n = 358 of the ADHDH+TD index patients and n = 1248 of the ADHD-TD index patients). We assessed psychopathological symptoms in index patients and siblings by using the Strength and Difficulties Questionnaire (SDQ) and the parent and teacher Conners' long version Rating Scales (CRS). For disorder classification the Parental Account of Childhood Symptoms (PACS-Interview) was applied in n = 271 children. Odds ratio with the GENMOD procedure (PROCGENMOD) was used to test if the risk for ADHD, TD, and ADHD-FTD in siblings was associated with the related index patients' diagnoses. In order to get an estimate for specificity we compared the four groups for general psychopathological symptoms. Results: Co-existing ADHD-FTD in index patients increased the risk of both comorbid ADHD-FTD and TD in the siblings of these index patients. These effects did not extend to general psychopathology. Interpretation: Co-existence of ADHD+FTD may segregate in families. The same holds true for TD (without ADHD). Hence, the segregation of TD (included in both groups) seems to be the determining factor, independent of further behavioral problems. This close relationship between ADHD and TD supports the clinical approach to carefully assess ADHD in any case of TD."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2016"],["dc.identifier.doi","10.3389/fpsyg.2016.01060"],["dc.identifier.isi","000379876400001"],["dc.identifier.pmid","27486412"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/13495"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/40067"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Frontiers Media Sa"],["dc.relation.issn","1664-1078"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Familiality of Co-existing ADHD and Tic Disorders: Evidence from a Large Sibling Study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e0178866"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","PLoS ONE"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Uebel-von Sandersleben, Henrik"],["dc.contributor.author","Albrecht, Bjorn"],["dc.contributor.author","Rothenberger, Aribert"],["dc.contributor.author","Fillmer-Heise, Anke"],["dc.contributor.author","Roessner, Veit"],["dc.contributor.author","Sergeant, Joseph"],["dc.contributor.author","Tannock, Rosemary"],["dc.contributor.author","Banaschewski, Tobias"],["dc.date.accessioned","2018-11-07T10:22:46Z"],["dc.date.available","2018-11-07T10:22:46Z"],["dc.date.issued","2017"],["dc.description.abstract","Objective Attention Deficit / Hyperactivity Disorder (ADHD) and Chronic Tic Disorder (CTD) are two common and frequently co-existing disorders, probably following an additive model. But this is not yet clear for the basic sensory function of colour processing sensitive to dopaminergic functioning in the retina and higher cognitive functions like attention and interference control. The latter two reflect important aspects for psychoeducation and behavioural treatment approaches. Methods Colour discrimination using the Farnsworth-Munsell 100-hue Test, sustained attention during the Frankfurt Attention Inventory (FAIR), and interference liability during Colour- and Counting-Stroop-Tests were assessed to further clarify the cognitive profile of the co-existence of ADHD and CTD. Altogether 69 children were classified into four groups: ADHD (N = 14), CTD (N = 20), ADHD+CTD (N = 20) and healthy Controls (N = 15) and compared in cognitive functioning in a 2x2-factorial statistical model. Results Difficulties with colour discrimination were associated with both ADHD and CTD factors following an additive model, but in ADHD these difficulties tended to be more pronounced on the blue-yellow axis. Attention problems were characteristic for ADHD but not CTD. Interference load was significant in both Colour-and Counting-Stroop-Tests and unrelated to colour discrimination. Compared to Controls, interference load in the Colour-Stroop was higher in pure ADHD and in pure CTD, but not in ADHD+CTD, following a sub-additive model. In contrast, interference load in the Counting-Stroop did not reveal ADHD or CTD effects. Conclusion The co-existence of ADHD and CTD is characterized by additive as well as sub-additive performance impairments, suggesting that their co-existence may show simple additive characteristics of both disorders or a more complex interaction, depending on demand. The equivocal findings on interference control may indicate limited validity of the Stroop-Paradigm for clinical assessments."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2017"],["dc.identifier.doi","10.1371/journal.pone.0178866"],["dc.identifier.isi","000402923200058"],["dc.identifier.pmid","28594866"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14557"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/42336"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Public Library Science"],["dc.relation.issn","1932-6203"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Revisiting the co-existence of Attention-Deficit/Hyperactivity Disorder and Chronic Tic Disorder in childhood-The case of colour discrimination, sustained attention and interference control"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","267"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","European Child & Adolescent Psychiatry"],["dc.bibliographiccitation.lastpage","275"],["dc.bibliographiccitation.volume","20"],["dc.contributor.author","Becker, Andreas"],["dc.contributor.author","Roessner, Veit"],["dc.contributor.author","Breuer, Dieter"],["dc.contributor.author","Döpfner, Manfred"],["dc.contributor.author","Rothenberger, Aribert"],["dc.date.accessioned","2019-07-09T11:53:14Z"],["dc.date.available","2019-07-09T11:53:14Z"],["dc.date.issued","2011"],["dc.description.abstract","Although ADHD significantly affects the quality of life (QoL) of patients and their families, QoL in children with ADHD has rarely been investigated in association with psychopathological profile, and the relationship remains unclear. The open-label OBSEER study evaluated the effectiveness and tolerability of Equasym XL®, a modified-release methylphenidate, in routine care of children and adolescents (aged 6–17 years) with ADHD. At baseline, questionnaires assessing psychopathological profile (Strengths and Difficulties Questionnaire, SDQ; parental ratings) and QoL (KINDL; parent, child or adolescent versions) were completed; QoL was reassessed at final visit. We analysed the relationship between psychopathology and parent/patient-rated QoL in ADHD at baseline. Data from 721 consecutively referred children and adolescents were analysed. QoL was similarly low from parent and self-ratings and independent of severity on the SDQ subscale hyperactivity/inattention. Self-ratings indicated that additional conduct disorder was associated with further reduction in QoL. Similarly, children with high scores from parent and adolescent ratings on the SDQ subscale conduct problems had reduced QoL on some KINDL subscales. Adolescents with ADHD not receiving medication at baseline reported lower QoL than those already on medication. Results show that children and adolescents with ADHD have low QoL, independent of core symptom severity. Additional conduct problems may further impact QoL negatively, while ADHD medication use may show a trend towards improved QoL. Not all psychopathological problems associated with ADHD affect QoL similarly. As parents appear to have a less critical view of QoL compared with children’s self-ratings, both parent and child ratings should be included in clinical assessments."],["dc.identifier.doi","10.1007/s00787-011-0204-2"],["dc.identifier.fs","579466"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/7141"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/60372"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.publisher","Springer"],["dc.publisher.place","Berlin/Heidelberg"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.subject.ddc","610"],["dc.title","Relationship between quality of life and psychopathological profile: data from an observational study in children with ADHD"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","314"],["dc.bibliographiccitation.journal","Frontiers in Human Neuroscience"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","August, Julia M."],["dc.contributor.author","Rothenberger, Aribert"],["dc.contributor.author","Baudewig, Juergen"],["dc.contributor.author","Roessner, Veit"],["dc.contributor.author","Dechent, Peter"],["dc.date.accessioned","2018-11-07T09:56:00Z"],["dc.date.available","2018-11-07T09:56:00Z"],["dc.date.issued","2015"],["dc.description.abstract","Background: Cortico-subcortical circuits are organized into the sensorimotor, associative, and limbic loop. These neuronal preconditions play an important role regarding the understanding and treatment of behavioral problems in children. Differencing evidence argues for a lateralized organization of the sensorimotor loop and a bilateral (i.e., non-lateralized) organization of the associative loop. However, a firm behavioral-neurobiological distinction of these circuits has been difficult, specifically in children. Objectives: Thus, the aim was a comprehensive functional visualization and differentiation of the sensorimotor and the associative circuit during childhood. As a new approach, laterality and rostrality features were used to distinguish between the two circuits within one single motor task. Methods: Twenty-four healthy boys performed self-paced index finger tapping with each hand separately during functional magnetic resonance imaging at 3 Tesla. Results: A contrast analysis for left against right hand movement revealed lateralized activation in typical sensorimotor regions such as primary sensorimotor cortex, caudal supplementary motor area (SMA), caudal putamen, and thalamus. A conjunction analysis confirmed bilateral involvement of known associative regions including pre-SMA, rostral SMA, and rostral putamen. Conclusion: A functional visualization of two distinct corticostriatal circuits is provided in childhood. Both the sensorimotor and associative circuit may be discriminated by their laterality characteristics already in minors. Additionally, the results support the concept of a modified functional subdivision of the SMA in a rostral (associative) and caudal (motor) part. A further development of this approach might help to nurture behavioral assessment and neurofeedback training in child mental health."],["dc.description.sponsorship","Open-Access Publikationsfonds 2015"],["dc.identifier.doi","10.3389/fnhum.2015.00314"],["dc.identifier.isi","000356073700002"],["dc.identifier.pmid","26082707"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/11977"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/36874"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Frontiers Media S.A."],["dc.relation.eissn","1662-5161"],["dc.relation.issn","1662-5161"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","May functional imaging be helpful for behavioral assessment in children? Regions of motor and associative cortico-subcortical circuits can be differentiated by laterality and rostrality"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","71"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","European Child & Adolescent Psychiatry"],["dc.bibliographiccitation.lastpage","74"],["dc.bibliographiccitation.volume","20"],["dc.contributor.author","Roessner, Veit"],["dc.contributor.author","Hoekstra, Pieter J."],["dc.contributor.author","Rothenberger, Aribert"],["dc.date.accessioned","2018-11-07T08:59:23Z"],["dc.date.available","2018-11-07T08:59:23Z"],["dc.date.issued","2011"],["dc.description.abstract","Classification of tic disorders will be revised in the forthcoming edition of the Diagnostic and Statistical Manual of Mental Disorders (5th ed.; DSM-5). We do not support the suggestion to move tic disorders to \"Anxiety and Obsessive-Compulsive Disorders\", if the section \"Disorders Usually First Diagnosed in Infancy, Childhood, or Adolescence\" is not retained. Other than that, most proposed changes of the criteria for tic disorders contain a number of welcome improvements, e.g., the more unified definition of tics including the removal of the term \"stereotyped\" and the better capture of the temporal pattern of tics (e.g., removal of the maximum 3 months criterion for a tic-free period in chronic tic disorders). But, unfortunately there are some inconsistencies in detail, e.g., the unification of diagnostic criteria for tic disorders had not been consistently pursued in transient tic disorder. In sum, the proposed DSM-5 criteria could be seen as an important step forward particularly in clinical routine. However, continued research is needed to justify the existing and proposed classification of tic disorders as well as to better clarify what other changes should be made in the DSM-5 and beyond."],["dc.identifier.doi","10.1007/s00787-010-0143-3"],["dc.identifier.isi","000287324500004"],["dc.identifier.pmid","21076848"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6935"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/23882"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","1018-8827"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Tourette's disorder and other tic disorders in DSM-5: a comment"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","857"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Journal of Neural Transmission"],["dc.bibliographiccitation.lastpage","861"],["dc.bibliographiccitation.volume","115"],["dc.contributor.author","Heise, C. A."],["dc.contributor.author","Wanschura, V."],["dc.contributor.author","Albrecht, B."],["dc.contributor.author","Uebel, Henrik"],["dc.contributor.author","Roessner, Veit"],["dc.contributor.author","Himpel, S."],["dc.contributor.author","Paulus, Walter J."],["dc.contributor.author","Rothenberger, A."],["dc.contributor.author","Tergau, Frithjof"],["dc.date.accessioned","2018-11-07T11:14:45Z"],["dc.date.available","2018-11-07T11:14:45Z"],["dc.date.issued","2008"],["dc.description.abstract","Electrophysiologically, Tourette syndrome (TS) is characterized by shortened cortical silent period (CSP), reflecting decreased motor inhibition. However, voluntary versus involuntary aspects of inhibitory functions in TS are not well understood. Hence, investigating voluntary motor drive (VMD) could help to elucidate this issue. A group of 14 healthy adolescents was compared with subjects of same age suffering from TS with (N = 6) and without (N = 6) presence of distal tics. Basic resting and active motor thresholds (RMT and AMT, respectively) as well as suprathreshold transcranial magnetic stimulation-conditioned RMT and AMT were determined during the CSP. The difference between AMT and RMT was considered as VMD quantum. No group-differences were found in RMT or AMT. Subjects with distal tics showed reduced VMD compared to healthy controls while patients without distal tics did not differ from controls. In the second half of CSP, patients with distal tics showed also diminished VMD compared to tic-patients without distal tics. The findings support the notion, that TS shows possible reduction of VMD and is associated with central motor threshold alterations confined to the very motor networks related to the tics observed."],["dc.identifier.doi","10.1007/s00702-007-0010-7"],["dc.identifier.isi","000256472400010"],["dc.identifier.pmid","18196201"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?goescholar/3556"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/54212"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","Wien"],["dc.relation.issn","0300-9564"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Voluntary motor drive: possible reduction in Tourette syndrome"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]