Rothenberger, Aribert

[["dc.bibliographiccitation.firstpage","147"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Journal of Attention Disorders"],["dc.bibliographiccitation.lastpage","156"],["dc.bibliographiccitation.volume","14"],["dc.contributor.author","Falissard, Bruno"],["dc.contributor.author","Coghill, David"],["dc.contributor.author","Rothenberger, Aribert"],["dc.contributor.author","Lorenzo, Maria"],["dc.date.accessioned","2018-11-07T08:39:48Z"],["dc.date.available","2018-11-07T08:39:48Z"],["dc.date.issued","2010"],["dc.description.abstract","Objective: The article discusses the ADHD Observational Research in Europe (ADORE) study that examined the impact of early treatment choices on outcome within the first few months, in previously untreated children with impairing inattention, impulsivity, and hyperactivity. Methods: Data are collected from a longitudinal, observational study conducted in 10 European countries that involve 1,478 children (aged 6 to 18 years) with symptoms of hyperactivity, impulsivity, or inattentiveness. Linear model with a propensity score adjustment compares the decrease in ADHD-RS scores between baseline and last recorded visit across treatment groups (2 to 5 months). Results: At baseline, 49.9% of participants are prescribed pharmacotherapy and 44.3% a psychosocial intervention. Analysis of the effect of treatment on the evolution of ADHD-RS scores shows a positive effect of medications and either an insignificant or negative effect of psychosocial intervention. Conclusions: Early use of medication effectively reduces ADHD symptoms in routine clinical practice in Europe. The effect of psychosocial intervention has to be interpreted cautiously because the number, length, and level of standard of the sessions are not taken into account in the analyses. (J. of Att. Dis. 2007)"],["dc.identifier.doi","10.1177/1087054709347173"],["dc.identifier.isi","000280934800007"],["dc.identifier.pmid","19767593"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/13059"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/19085"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Sage Publications Inc"],["dc.relation.issn","1087-0547"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Short-Term Effectiveness of Medication and Psychosocial Intervention in a Cohort of Newly Diagnosed Patients With Inattention, Impulsivity, and Hyperactivity Problems"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","990"],["dc.bibliographiccitation.journal","Frontiers in human neuroscience"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Gevensleben, Holger"],["dc.contributor.author","Albrecht, Björn"],["dc.contributor.author","Lütcke, Henry"],["dc.contributor.author","Auer, Tibor"],["dc.contributor.author","Dewiputri, Wan Ilma"],["dc.contributor.author","Schweizer, Renate"],["dc.contributor.author","Moll, Gunther"],["dc.contributor.author","Heinrich, Hartmut"],["dc.contributor.author","Rothenberger, Aribert"],["dc.date.accessioned","2019-07-09T11:40:54Z"],["dc.date.available","2019-07-09T11:40:54Z"],["dc.date.issued","2014"],["dc.description.abstract","To elucidate basic mechanisms underlying neurofeedback we investigated neural mechanisms of training of slow cortical potentials (SCPs) by considering EEG- and fMRI. Additionally, we analyzed the feasibility of a double-blind, placebo-controlled design in NF research based on regulation performance during treatment sessions and self-assessment of the participants. Twenty healthy adults participated in 16 sessions of SCPs training: 9 participants received regular SCP training, 11 participants received sham feedback. At three time points (pre, intermediate, post) fMRI and EEG/ERP-measurements were conducted during a continuous performance test (CPT). Performance-data during the sessions (regulation performance) in the treatment group and the placebo group were analyzed. Analysis of EEG-activity revealed in the SCP group a strong enhancement of the CNV (electrode Cz) at the intermediate assessment, followed by a decrease back to baseline at the post-treatment assessment. In contrast, in the placebo group a continuous but smaller increase of the CNV could be obtained from pre to post assessment. The increase of the CNV in the SCP group at intermediate testing was superior to the enhancement in the placebo group. The changes of the CNV were accompanied by a continuous improvement in the test performance of the CPT from pre to intermediate to post assessment comparable in both groups. The change of the CNV in the SCP group is interpreted as an indicator of neural plasticity and efficiency while an increase of the CNV in the placebo group might reflect learning and improved timing due to the frequent task repetition. In the fMRI analysis evidence was obtained for neuronal plasticity. After regular SCP neurofeedback activation in the posterior parietal cortex decreased from the pre- to the intermediate measurement and increased again in the post measurement, inversely following the U-shaped increase and decrease of the tCNV EEG amplitude in the SCP-trained group. Furthermore, we found a localized increase of activity in the anterior cingulate cortex (ACC). Analyses of the estimation of treatment assignment by the participants indicate feasibility of blinding. Participants could not assess treatment assignment confidently. Participants of the SCP-group improved regulation capability during treatment sessions (in contrast to the participants of the placebo-group), although regulation capability appeared to be instable, presumably due to diminished confidence in the training (SCP- or sham-training). Our results indicate that SCP training in healthy adults might lead to functional changes in neuronal circuits serving cognitive preparation even after a limited number of sessions."],["dc.format.extent","13"],["dc.identifier.doi","10.3389/fnhum.2014.00990"],["dc.identifier.fs","607730"],["dc.identifier.pmid","25566020"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/11462"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/58291"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","1662-5161"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Neurofeedback of slow cortical potentials: neural mechanisms and feasibility of a placebo-controlled design in healthy adults."],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","3"],["dc.bibliographiccitation.journal","Child and Adolescent Psychiatry and Mental Health"],["dc.bibliographiccitation.volume","3"],["dc.contributor.author","Wehmeier, Peter M."],["dc.contributor.author","Schacht, Alexander"],["dc.contributor.author","Rothenberger, Aribert"],["dc.date.accessioned","2019-07-09T11:52:38Z"],["dc.date.available","2019-07-09T11:52:38Z"],["dc.date.issued","2009"],["dc.description.abstract","Background In many developed countries, the treatment of hyperkinetic disorder (or ADHD) consumes a considerable amount of resources. The primary aim of this study was to determine change in the direct cost of treatment for children and adolescents with hyperkinetic disorder in Germany over time, and compare the cost with the cost of treatment for two physical disorders: epilepsy and asthma. Methods The German Federal Statistical Office provided data on the direct cost of treating hyperkinetic disorder, epilepsy and asthma in Germany for 2002, 2004, and 2006. The direct costs of treatment incurred by hyperkinetic disorder in these years were compared with those incurred by epilepsy and asthma. Results The total direct cost of treatment for the hyperkinetic disorder was € 177 million in 2002, € 234 million in 2004, and € 341 million in 2006. The largest proportion of the cost was incurred by the age group < 15 years: € 158 million in 2002, € 205 million in 2004, and € 287 million in 2006. The direct cost of treatment for epilepsy in this age group was a total of € 157 million in 2002, € 155 million in 2004, and € 155 million in 2006. For asthma, the total direct cost of treatment in this age group was € 266 million in 2002, € 257 million in 2004, and € 272 million in 2006. Conclusion The direct cost of treatment for hyperkinetic disorder in the age group < 15 years increased considerably between 2002 and 2006. Over the same period of time and for the same age group, expenditure for epilepsy and asthma was more or less constant. The increase in expenditure for the treatment of hyperkinetic disorder may be due to increasing demand for diagnostic and therapeutic services and improved availability of such services. The study is limited by the difficulty of obtaining consistent data on the direct cost of treatment for both physical and psychiatric disorders in Germany."],["dc.identifier.doi","10.1186/1753-2000-3-3"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/5770"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/60243"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY 2.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/2.0"],["dc.subject.ddc","610"],["dc.title","Change in the direct cost of treatment for children and adolescents with hyperkinetic disorder in Germany over a period of four years"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","153"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","European Child & Adolescent Psychiatry"],["dc.bibliographiccitation.lastpage","154"],["dc.bibliographiccitation.volume","20"],["dc.contributor.author","Roessner, Veit"],["dc.contributor.author","Rothenberger, Aribert"],["dc.contributor.author","Rickards, Hugh"],["dc.contributor.author","Hoekstra, Pieter J."],["dc.date.accessioned","2018-11-07T08:57:31Z"],["dc.date.available","2018-11-07T08:57:31Z"],["dc.date.issued","2011"],["dc.identifier.doi","10.1007/s00787-011-0165-5"],["dc.identifier.isi","000288903000001"],["dc.identifier.pmid","21445722"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/7337"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/23418"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","1018-8827"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","European clinical guidelines for Tourette Syndrome and other tic disorders"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.subtype","letter_note"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","European Child & Adolescent Psychiatry"],["dc.bibliographiccitation.volume","22"],["dc.contributor.author","Rothenberger, Aribert"],["dc.contributor.author","Minderaa, Ruud"],["dc.date.accessioned","2018-11-07T09:30:45Z"],["dc.date.available","2018-11-07T09:30:45Z"],["dc.date.issued","2013"],["dc.format.extent","51"],["dc.identifier.doi","10.1007/s00787-012-0323-4"],["dc.identifier.isi","000313018300008"],["dc.identifier.pmid","23001248"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/8828"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/31383"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","1018-8827"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Recommendations for a better patient care in daily clinical practice: a joint perspective of ESCAP and ECAP"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.subtype","letter_note"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","933139"],["dc.bibliographiccitation.journal","Frontiers in Behavioral Neuroscience"],["dc.bibliographiccitation.volume","16"],["dc.contributor.affiliation","Ganjeh, Parisa; 1Department of Child and Adolescent Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany"],["dc.contributor.affiliation","Hagmayer, York; 2Department of Cognitive Science and Decision Psychology, Georg-Elias-Müller-Institute for Psychology, University of Göttingen, Göttingen, Germany"],["dc.contributor.affiliation","Meyer, Thomas; 3Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany"],["dc.contributor.affiliation","Kuhnert, Ronny; 4Unit Mental Health, Department of Epidemiology and Health Monitoring, Robert Koch Institute, Berlin, Germany"],["dc.contributor.affiliation","Ravens-Sieberer, Ulrike; 5Department of Child and Adolescent Psychiatry, Psychotherapy and Psychosomatics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany"],["dc.contributor.affiliation","von Steinbuechel, Nicole; 6Institute of Medical Psychology and Medical Sociology, University Medical Center Göttingen, Göttingen, Germany"],["dc.contributor.affiliation","Rothenberger, Aribert; 1Department of Child and Adolescent Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany"],["dc.contributor.affiliation","Becker, Andreas; 1Department of Child and Adolescent Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany"],["dc.contributor.author","Ganjeh, Parisa"],["dc.contributor.author","Hagmayer, York"],["dc.contributor.author","Meyer, Thomas"],["dc.contributor.author","Kuhnert, Ronny"],["dc.contributor.author","Ravens-Sieberer, Ulrike"],["dc.contributor.author","von Steinbuechel, Nicole"],["dc.contributor.author","Rothenberger, Aribert"],["dc.contributor.author","Becker, Andreas"],["dc.date.accessioned","2022-11-01T10:17:20Z"],["dc.date.available","2022-11-01T10:17:20Z"],["dc.date.issued","2022"],["dc.date.updated","2022-11-11T13:13:21Z"],["dc.description.abstract","Studies have shown that physical activity (PA) can provide a helpful, low-risk, and cost-effective intervention for children and adolescents suffering from mental health problems. This longitudinal study aimed to assess whether PA prevents the development of mental health problems, such as attention-deficit/hyperactivity disorder (ADHD) in children and adolescents. Data were analyzed from the German Health Interview and Examination Survey for Children and Adolescents (KiGGS) collected from more than 15.000 children and adolescents at three different time points over a period of more than 10 years. Parents scored the PA of the study participants on three frequency levels according to WHO recommendations, and mental health problems were assessed by means of the Strengths and Difficulties Questionnaire (SDQ). The total problem score (SDQ-Total) and the hyperactivity/inattention symptoms sub-scale (SDQ-H/I) were used in an autoregressive cross-lagged model to examine their relationship with PA. The results showed that PA of boys and girls at preschool age was inversely associated with the occurrence of mental health problems and, in particular, ADHD symptoms about 6 years later. Higher levels of PA were associated with better general mental health and fewer ADHD symptoms at the next time point (Wave 1). These effects were not observed from preadolescence (Wave 1) to adolescence (Wave 2), neither for girls nor for boys. These findings indicate that medium-to-high PA may be a supportive factor for good mental health in children in preschool and elementary school. Future studies will have to show whether PA may be a helpful add-on for interventional programs for improving general mental health and alleviating ADHD symptoms among children and adolescents."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2022"],["dc.identifier.doi","10.3389/fnbeh.2022.933139"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/116787"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-605"],["dc.publisher","Frontiers Media S.A."],["dc.relation.eissn","1662-5153"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0/"],["dc.title","Physical activity and the development of general mental health problems or attention-deficit hyperactivity disorder (ADHD) symptoms in children and adolescents: A cross-lagged panel analysis of long-term follow-up epidemiological data"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","737"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","European Child & Adolescent Psychiatry"],["dc.bibliographiccitation.lastpage","739"],["dc.bibliographiccitation.volume","19"],["dc.contributor.author","Sergeant, Joseph A."],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Buitelar, Jan"],["dc.contributor.author","Coghill, David"],["dc.contributor.author","Danckaerts, Marina"],["dc.contributor.author","Doepfner, Manfred"],["dc.contributor.author","Rothenberger, A."],["dc.contributor.author","Santosh, Paramala"],["dc.contributor.author","Sonuga-Barke, Edmund J."],["dc.contributor.author","Steinhausen, Hans-Christoph"],["dc.contributor.author","Taylor, Eric A."],["dc.contributor.author","Zuddas, Alessandro"],["dc.date.accessioned","2018-11-07T08:39:39Z"],["dc.date.available","2018-11-07T08:39:39Z"],["dc.date.issued","2010"],["dc.description.abstract","The Eunethydis ADHD Guidelines group set out here the ethical principles governing the relationship between the group and industry. The principles set out here are provided to ensure that this is both done and seen to be done. The impetus for these guidelines comes from within the Group and is linked to the recognition for the need for an open and transparent basis for Group-industry relations, especially in the light of the present concern that the pharmaceutical industry may be exerting a growing influence on the actions of researchers and clinicians in the ADHD field."],["dc.identifier.doi","10.1007/s00787-010-0114-8"],["dc.identifier.isi","000281162600006"],["dc.identifier.pmid","20549526"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6776"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/19048"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.haserratum","/handle/2/91541"],["dc.relation.issn","1018-8827"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Eunethydis: a statement of the ethical principles governing the relationship between the European group for ADHD guidelines, and its members, with commercial for-profit organisations"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","602"],["dc.bibliographiccitation.journal","Frontiers in Human Neuroscience"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Arns, Martijn"],["dc.contributor.author","Heinrich, Hartmut"],["dc.contributor.author","Ros, Tomas"],["dc.contributor.author","Rothenberger, Aribert"],["dc.contributor.author","Strehl, Ute"],["dc.date.accessioned","2018-11-07T09:49:59Z"],["dc.date.available","2018-11-07T09:49:59Z"],["dc.date.issued","2015"],["dc.identifier.doi","10.3389/fnhum.2015.00602"],["dc.identifier.isi","000366491200001"],["dc.identifier.pmid","26578942"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/12794"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/35616"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","1662-5161"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Editorial: Neurofeedback in ADHD"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","editorial_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1183"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Neuroscience"],["dc.bibliographiccitation.lastpage","1191"],["dc.bibliographiccitation.volume","167"],["dc.contributor.author","Roessner, Veit"],["dc.contributor.author","Sagvolden, T."],["dc.contributor.author","DasBanerjee, T."],["dc.contributor.author","Middleton, Frank A."],["dc.contributor.author","Faraone, Steven V."],["dc.contributor.author","Walaas, S. I."],["dc.contributor.author","Becker, A."],["dc.contributor.author","Rothenberger, A."],["dc.contributor.author","Bock, Nathalie"],["dc.date.accessioned","2018-11-07T08:42:20Z"],["dc.date.available","2018-11-07T08:42:20Z"],["dc.date.issued","2010"],["dc.description.abstract","The spontaneously hypertensive rat (SHR/NCrI) is a validated model of attention-deficit/hyperactivity disorder (ADHD) combined subtype, whereas a recently identified sub-strain of the Wistar Kyoto rat (WKY/NCrI) is a model of ADHD inattentive subtype. In this study, we first examined the expression of genes involved in dopamine signaling and metabolism in the dorsal striatum and ventral mesencephalon of these two rat strains, as well as three reference control strains (WKY/NHsd, WK/HanTac, and SD/NTac) using quantitative real time RT-PCR. Next, striatal dopamine transporter (DAT) density was determined by ligand binding assay in the two ADHD-like strains at different developmental stages and after methylphenidate treatment. In adult rats, the mRNA expression of DAT and tyrosine hydroxylase was elevated in SHR/NCrI and WKY/NCrI rats compared to control strains, with differences between SHR/NCrI and WKY/NCrI rats also evident. During normal development, changes of striatal DAT densities occurred in both strains with lower densities in WKY/NCrI compared to SHR/NCrI after day 25. Two-weeks methylphenidate treatment during different developmental stages was associated with decreased striatal DAT density in both rat strains compared to the non-treated rats with more pronounced effects followed prepubertal treatment. These results suggest differences in the pathophysiology of the combined versus the predominantly inattentive animal model of ADHD. Finally, treatment with methylphenidate might reduce elevated DAT levels more effectively in the combined subtype especially when applied before puberty. (C) 2010 IBRO. Published by Elsevier Ltd. All rights reserved."],["dc.identifier.doi","10.1016/j.neuroscience.2010.02.073"],["dc.identifier.isi","000277434800022"],["dc.identifier.pmid","20211696"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6332"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/19675"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Pergamon-elsevier Science Ltd"],["dc.relation.issn","0306-4522"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","METHYLPHENIDATE NORMALIZES ELEVATED DOPAMINE TRANSPORTER DENSITIES IN AN ANIMAL MODEL OF THE ATTENTION-DEFICIT/HYPERACTIVITY DISORDER COMBINED TYPE, BUT NOT TO THE SAME EXTENT IN ONE OF THE ATTENTION-DEFICIT/HYPERACTIVITY DISORDER INATTENTIVE TYPE"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","2059"],["dc.bibliographiccitation.journal","Frontiers in Psychology"],["dc.bibliographiccitation.volume","7"],["dc.contributor.author","Kirov, Roumen"],["dc.contributor.author","Brand, Serge"],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Rothenberger, Aribert"],["dc.date.accessioned","2018-11-07T10:28:27Z"],["dc.date.available","2018-11-07T10:28:27Z"],["dc.date.issued","2017"],["dc.description.abstract","Rapid eye movement (REM) sleep has been shown to be related to many adaptive cognitive and behavioral functions. However, its precise functions are still elusive, particularly in developmental psychiatric disorders. The present study aims at investigating associations between polysomnographic (PSG) REM sleep measurements and neurobehavioral functions in children with common developmental psychiatric conditions compared to typically developing children (TDC). Twenty-four children with attention-deficit/hyperactivity disorder (ADHD), 21 with Tourette syndrome/tic disorder (TD), 21 with ADHD/TD comorbidity, and 22 TDC, matched for age and gender, underwent a two-night PSG, and their psychopathological scores and intelligence quotient (IQ) were assessed. Major PSG findings showed more REM sleep and shorter REM latency in the children with psychiatric disorders than in the TDC. Multiple regression analyses revealed that in groups with developmental psychopathology, REM sleep proportion correlated positively with scores of inattention and negatively with performance IQ. In contrast, in the group of TDC, REM sleep proportion correlated negatively with scores of inattention and positively with performance IQ. Whilst shorter REM latency was associated with greater inattention scores in children with psychopathology, no such an association existed in the group of TDC. Altogether, these results indicate an opposite impact of REM sleep on neurobehavioral functioning, related to presence or absence of developmental psychiatric disorders. Our findings suggest that during development, REM sleep functions may interact dissimilarly with different pathways of brain maturation."],["dc.description.sponsorship","University Medical Center of Goettingen, Goettingen, Germany"],["dc.identifier.doi","10.3389/fpsyg.2016.02059"],["dc.identifier.isi","000391399200002"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14229"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/43422"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Frontiers Media Sa"],["dc.relation.issn","1664-1078"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Opposite Impact of REM Sleep on Neurobehavioral Functioning in Children with Common Psychiatric Disorders Compared toTypically Developing Children"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]