Bennati, Marina

[["dc.bibliographiccitation.firstpage","4"],["dc.bibliographiccitation.journal","Progress in Nuclear Magnetic Resonance Spectroscopy"],["dc.bibliographiccitation.lastpage","28"],["dc.bibliographiccitation.volume","64"],["dc.contributor.author","Griesinger, Christian"],["dc.contributor.author","Bennati, Marina"],["dc.contributor.author","Vieth, H. M."],["dc.contributor.author","Luchinat, Claudio"],["dc.contributor.author","Parigi, Giacomo"],["dc.contributor.author","Hoefer, Peter"],["dc.contributor.author","Engelke, Frank"],["dc.contributor.author","Glaser, S. J."],["dc.contributor.author","Denysenkov, V."],["dc.contributor.author","Prisner, T. F."],["dc.date.accessioned","2017-09-07T11:48:51Z"],["dc.date.available","2017-09-07T11:48:51Z"],["dc.date.issued","2012"],["dc.identifier.doi","10.1016/j.pnmrs.2011.10.002"],["dc.identifier.gro","3142509"],["dc.identifier.isi","000304898700004"],["dc.identifier.pmid","22578315"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/8868"],["dc.notes.intern","WoS Import 2017-03-10 / Funder: European Design Study Project; European Commission"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Pergamon-elsevier Science Ltd"],["dc.relation.issn","0079-6565"],["dc.title","Dynamic nuclear polarization at high magnetic fields in liquids"],["dc.type","review"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","207"],["dc.bibliographiccitation.issue","1-2"],["dc.bibliographiccitation.journal","Applied Magnetic Resonance"],["dc.bibliographiccitation.lastpage","221"],["dc.bibliographiccitation.volume","43"],["dc.contributor.author","Lottmann, Philip"],["dc.contributor.author","Marquardsen, Thorsten"],["dc.contributor.author","Krahn, Alexander"],["dc.contributor.author","Tavernier, Andreas"],["dc.contributor.author","Hoefer, Peter"],["dc.contributor.author","Bennati, Marina"],["dc.contributor.author","Engelke, Frank"],["dc.contributor.author","Griesinger, Christian"],["dc.date.accessioned","2017-09-07T11:48:50Z"],["dc.date.available","2017-09-07T11:48:50Z"],["dc.date.issued","2012"],["dc.description.abstract","A liquid state shuttle dynamic nuclear polarization (DNP) spectrometer is presented, featuring several technical modifications that increase stability and improve reproducibility. For the protons of l-tryptophan, the signal enhancement and the DNP spin properties, such as relaxation, were measured and compared with each other. The calculated coupling factors suggest that the proton accessibility for the polarizer molecule has an important influence on the DNP enhancement. In general, short proton spin longitudinal relaxation times without radical reduce the detectable enhancement by decreasing the leakage factor and increasing the relaxation losses during the course of the sample transfer. The usage of a global enhancement factor gives a more complete overview of the capabilities for the described experimental setup. Global enhancements of up to -4.2 for l-tryptophan protons are found compared to pure Boltzmann enhancements of up to -2.4."],["dc.identifier.doi","10.1007/s00723-012-0345-6"],["dc.identifier.gro","3142499"],["dc.identifier.isi","000306421200018"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/8857"],["dc.notes.intern","WoS Import 2017-03-10 / Funder: Max Planck Society; Bio-NMR project [261863]"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Springer"],["dc.publisher.place","Wien"],["dc.relation.issn","0937-9347"],["dc.title","Evaluation of a Shuttle DNP Spectrometer by Calculating the Coupling and Global Enhancement Factors of L-Tryptophan"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","393"],["dc.bibliographiccitation.issue","3-4"],["dc.bibliographiccitation.journal","Applied Magnetic Resonance"],["dc.bibliographiccitation.lastpage","398"],["dc.bibliographiccitation.volume","34"],["dc.contributor.author","Hoefer, Peter"],["dc.contributor.author","Carl, Patrick"],["dc.contributor.author","Guthausen, Gisela"],["dc.contributor.author","Prisner, T."],["dc.contributor.author","Reese, Marcel"],["dc.contributor.author","Carlomagno, Teresa"],["dc.contributor.author","Griesinger, Christian"],["dc.contributor.author","Bennati, Marina"],["dc.date.accessioned","2017-09-07T11:48:15Z"],["dc.date.available","2017-09-07T11:48:15Z"],["dc.date.issued","2008"],["dc.description.abstract","The dynamic nuclear polarization effect between the nitroxide radical TEMPO and the H-1 protons of water solution was investigated at an electron pumping frequency of 9.7 GHz for different experimental conditions. In particular, we compared N-14-4-hydroxy-TEMPO (TEMPOL) with 4-oxo-TEMPO and evaluated the effect of H-2 and N-15 isotope labelling. Furthermore, we tested the effect of concomitant irradiation on both electron paramagnetic resonance (EPR) lines with the N-15-labelled compound. Our results show that the reduction in the EPR line width given by the H-1 and N-15 labelling and the collapse in the number of hyperfine lines due to N-15 substitution leads to the highest enhancement of epsilon = -140 ever reported in the literature. Concomitant pumping on two hyperfine lines does not give higher enhancements at our experimental conditions."],["dc.identifier.doi","10.1007/s00723-008-0118-4"],["dc.identifier.gro","3143260"],["dc.identifier.isi","000259125200015"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/754"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Springer"],["dc.publisher.place","Wien"],["dc.relation.issn","0937-9347"],["dc.title","Studies of dynamic nuclear polarization with nitroxides in aqueous solution"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","3254"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Journal of the American Chemical Society"],["dc.bibliographiccitation.lastpage","+"],["dc.bibliographiccitation.volume","130"],["dc.contributor.author","Hoefer, Peter"],["dc.contributor.author","Parigi, Giacomo"],["dc.contributor.author","Luchinat, Claudio"],["dc.contributor.author","Carl, Patrick"],["dc.contributor.author","Guthausen, Gisela"],["dc.contributor.author","Reese, Marcel"],["dc.contributor.author","Carlomagno, Teresa"],["dc.contributor.author","Griesinger, Christian"],["dc.contributor.author","Bennati, Marina"],["dc.date.accessioned","2017-09-07T11:48:46Z"],["dc.date.available","2017-09-07T11:48:46Z"],["dc.date.issued","2008"],["dc.description.abstract","The dynamic nuclear polarization (DNP) effect between the polarizers TEMPOL and trityl and the H-1 protons of water solution was investigated at two different magnetic fields corresponding to electron pumping frequencies of 9 and 94 GHz. For TEMPOL, large DNP enhancements up to about -100 (9 GHz) and -20 (94 GHz) were observed by continuous microwave irradiation on one of the three nitroxide hyperfine lines. These enhancements are considerably larger than those ever reported for this system and also larger than the ones we obtained with the second proposed polarizer agent, the trityl radical, under the same conditions. H-1 Overhauser coupling factors were extracted from NMRD relaxation dispersion experiments and used to estimate the degree of effective saturation of the TEMPOL EPR line. Our results show that nitroxide radicals are well-suited polarizers for DNP experiments in aqueous solutions at variable fields. The large enhancements open up attractive perspectives for the application potential of DNP in solution NMR with macromolecular complexes."],["dc.identifier.doi","10.1021/ja0783207"],["dc.identifier.gro","3143333"],["dc.identifier.isi","000253951900011"],["dc.identifier.pmid","18293980"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/836"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Amer Chemical Soc"],["dc.relation.issn","0002-7863"],["dc.title","Field dependent dynamic nuclear polarization with radicals in aqueous solution"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","15086"],["dc.bibliographiccitation.issue","42"],["dc.bibliographiccitation.journal","Journal of the American Chemical Society"],["dc.bibliographiccitation.lastpage","+"],["dc.bibliographiccitation.volume","131"],["dc.contributor.author","Reese, Marcel"],["dc.contributor.author","Tuerke, Maria-Teresa"],["dc.contributor.author","Tkach, Igor"],["dc.contributor.author","Parigi, Giacomo"],["dc.contributor.author","Luchinat, Claudio"],["dc.contributor.author","Marquardsen, Thorsten"],["dc.contributor.author","Tavernier, Andreas"],["dc.contributor.author","Hoefer, Peter"],["dc.contributor.author","Engelke, Frank"],["dc.contributor.author","Griesinger, Christian"],["dc.contributor.author","Bennati, Marina"],["dc.date.accessioned","2017-09-07T11:46:48Z"],["dc.date.available","2017-09-07T11:46:48Z"],["dc.date.issued","2009"],["dc.description.abstract","Dynamic nuclear polarization (DNP) permits increasing the NMR signal of nuclei by pumping the electronic spin transitions of paramagnetic centers nearby. This method is emerging as a powerful tool, to increase the inherent sensitivity of NMR in structural biology aiming at detection of macromolecules. In aqueous solution, additional technical issues associated with the penetration of microwaves in water and heating effects aggravate the performance of the experiment. To examine the feasibility of low-field (9.7 GHz/0.35 T) DNP in high resolution NMR, we have constructed the prototype of a two-field shuttle DNP spectrometer that polarizes nuclei at 9.7 GHz/0.35 T and detects the NMR spectrum at 14 T. We report our first H-1 and C-13 DNP enhancements with this spectrometer. Effective enhancements up to 15 were observed for small molecules at H-1 600 MHz/14 T as compared to the Boltzmann signal. The results provide a proof of principle for the feasibility of a shuttle DNP experiment and open up perspectives for the application potential of this method in solution NMR."],["dc.identifier.doi","10.1021/ja905959n"],["dc.identifier.gro","3143034"],["dc.identifier.isi","000271272000006"],["dc.identifier.pmid","19803508"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/504"],["dc.notes.intern","WoS Import 2017-03-10 / Funder: EU Design Study BIO-DNP; Max Planck Society"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Amer Chemical Soc"],["dc.relation.issn","0002-7863"],["dc.title","H-1 and C-13 Dynamic Nuclear Polarization in Aqueous Solution with a Two-Field (0.35 T/14 T) Shuttle DNP Spectrometer"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","5830"],["dc.bibliographiccitation.issue","22"],["dc.bibliographiccitation.journal","Physical Chemistry Chemical Physics"],["dc.bibliographiccitation.lastpage","5840"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Krahn, Alexander"],["dc.contributor.author","Lottmann, Philip"],["dc.contributor.author","Marquardsen, Thorsten"],["dc.contributor.author","Tavernier, Andreas"],["dc.contributor.author","Tuerke, Maria-Teresa"],["dc.contributor.author","Reese, Marcel"],["dc.contributor.author","Leonov, Andrei"],["dc.contributor.author","Bennati, Marina"],["dc.contributor.author","Hoefer, Peter"],["dc.contributor.author","Engelke, Frank"],["dc.contributor.author","Griesinger, Christian"],["dc.date.accessioned","2017-09-07T11:46:44Z"],["dc.date.available","2017-09-07T11:46:44Z"],["dc.date.issued","2010"],["dc.description.abstract","A DNP set-up is described where a liquid sample is hyperpolarized by the electron-nucleus Overhauser effect in a field of 0.34 T and transferred to a field of 14.09 T for NMR detection. In contrast to a previous set-up, using two dedicated magnets for polarization and detection, a dedicated ferroshim system was inserted into the bore of a 14.09 T shielded cryomagnet to provide a homogeneous low-field region in the stray field above the magnetic center. After polarization in the low-field the sample is transferred to the high-field magnetic center within 40 ms by a pneumatic shuttle system. In our set-up a standard high-resolution inverse (1)H/(13)C selective probe was used for NMR detection and a homebuilt EPR cavity, operating in the TM(110) mode was used for polarisation. First experimental data are presented. We observed a maximum proton Overhauser enhancement of up to epsilon(HF) = -3.7 in the high-field position for a 5 mM 4-Oxo-TEMPO-D, (15)N (TEMPONE)/H(2)O sample. While this reproduces the DNP enhancement observed also in the old set-up, with the new set-up we observe enhancement on larger molecules that were impossible to enhance in the old set-up. Therefore, we can demonstrate for the first time Overhauser enhanced high resolution proton spectra of glucose and 2,2-dimethyl-2-silapentane-5-sulfonic acid sodium salt (DSS) in D(2)O, where the high resolution spectrum was acquired in the high-field position after polarizing the sample in the low-field."],["dc.identifier.doi","10.1039/c003381b"],["dc.identifier.gro","3143003"],["dc.identifier.isi","000278098900014"],["dc.identifier.pmid","20461246"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/470"],["dc.notes.intern","WoS Import 2017-03-10 / Funder: Max Planck Gesellschaft; EU"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Royal Soc Chemistry"],["dc.relation.issn","1463-9076"],["dc.title","Shuttle DNP spectrometer with a two-center magnet"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","301"],["dc.bibliographiccitation.issue","3-4"],["dc.bibliographiccitation.journal","Applied Magnetic Resonance"],["dc.bibliographiccitation.lastpage","311"],["dc.bibliographiccitation.volume","34"],["dc.contributor.author","Reese, Marcel"],["dc.contributor.author","Lennartz, D."],["dc.contributor.author","Marquardsen, Thorsten"],["dc.contributor.author","Hoefer, Peter"],["dc.contributor.author","Tavernier, Andreas"],["dc.contributor.author","Carl, Patrick"],["dc.contributor.author","Schippmann, T."],["dc.contributor.author","Bennati, Marina"],["dc.contributor.author","Carlomagno, Teresa"],["dc.contributor.author","Engelke, Frank"],["dc.contributor.author","Griesinger, Christian"],["dc.date.accessioned","2017-09-07T11:48:15Z"],["dc.date.available","2017-09-07T11:48:15Z"],["dc.date.issued","2008"],["dc.description.abstract","First results from a liquid-state shuttle dynamic nuclear polarization (DNP) spectrometer are presented. The device polarizes a water sample at 9.7 GHz and 0.34 T in a commercial Bruker electron paramagnetic resonance (EPR) spectrometer and then transfers the sample via a homebuilt pneumatic shuttle device into the 600 MHz and 14.09 T nuclear magnetic resonance (NMR) spectrometer with a conventional NMR probe for detection. The shuttle transfer time is approximately 115 ms. Initial experiments measure the postshuttle proton magnetization compared with the Boltzmann magnetization at 14.09 T. The DNP enhancement factor at 0.34 T is reported for the nitroxide polarizer TEMPOL in water solution. Reduction of the magnetization during shuttling because of relaxation is quantified. Optimization of this apparatus is expected to bring the NMR enhancement factor for protons close to the theoretical enhancement maximum of -7.92."],["dc.identifier.doi","10.1007/s00723-008-0131-7"],["dc.identifier.gro","3143259"],["dc.identifier.isi","000259125200008"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/753"],["dc.notes.intern","WoS Import 2017-03-10 / Funder: BioDNP EU Initiative; Max Planck Society; Fonds der Chemischen Industrie"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Springer"],["dc.publisher.place","Wien"],["dc.relation.issn","0937-9347"],["dc.title","Construction of a liquid-state NMR DNP shuttle spectrometer: First experimental results and evaluation of optimal performance characteristics"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dspace.entity.type","Publication"]]