Bräuer, Anselm

[["dc.bibliographiccitation.firstpage","842"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","Der Anaesthesist"],["dc.bibliographiccitation.lastpage","850"],["dc.bibliographiccitation.volume","59"],["dc.contributor.author","Braeuer, Anselm"],["dc.contributor.author","Waeschle, Reiner M."],["dc.contributor.author","Heise, Daniel"],["dc.contributor.author","Perl, Tal Naggan"],["dc.contributor.author","Hinz, Jose Maria"],["dc.contributor.author","Quintel, M."],["dc.contributor.author","Bauer, M."],["dc.date.accessioned","2018-11-07T08:39:25Z"],["dc.date.available","2018-11-07T08:39:25Z"],["dc.date.issued","2010"],["dc.description.abstract","Despite the broad application of intraoperative warming new studies still show a high incidence of perioperative hypothermia. Therefore a prewarming program in the preoperative holding area was started. The efficacy of the prewarming program was assessed with an accompanying quality assurance check sheet over a period of 3 months. During the 3 month test period 127 patients were included. The median length from arrival in the holding area to beginning prewarming was 6 min and the average duration of prewarming was 46 +/- 38 min. During prewarming the core temperature rose by 0.3 +/- 0.4A degrees C to 37.1 +/- 0.5A degrees C and decreased to 36.3 +/- 0.5A degrees C after induction of anesthesia. At the end of the operation the core temperature was 36.4 +/- 0.5A degrees C and 14% of the patients were hypothermic. These data allow 2 conclusions: 1. Prewarming in the holding area is possible with a sufficient duration. 2. Prewarming is highly efficient even when performed over a relatively short duration."],["dc.identifier.doi","10.1007/s00101-010-1772-0"],["dc.identifier.isi","000281844600007"],["dc.identifier.pmid","20703440"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/18992"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0003-2417"],["dc.title","Preoperative prewarming as a routine measure. First experiences"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","375"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","MINERVA ANESTESIOLOGICA"],["dc.bibliographiccitation.lastpage","383"],["dc.bibliographiccitation.volume","75"],["dc.contributor.author","Quintel, M."],["dc.contributor.author","Braeuer, Anselm"],["dc.date.accessioned","2018-11-07T08:29:31Z"],["dc.date.available","2018-11-07T08:29:31Z"],["dc.date.issued","2009"],["dc.description.abstract","Currently, tracheostomy represents an established procedure for airway management in critically ill patients who require long-term respiratory support, and it is one of the most frequently performed surgical procedures in critically ill patients. It offers a number of practical and theoretical advantages when compared to conventional translaryngeal oro- or nasotracheal intubation, but is also associated with a number of serious complications. In the last 20 years, several retrospective studies, randomized prospective trials, and meta-analyses have been published to determine the best timing for tracheostomy. However, these studies presented conflicting results. All studies performed so far in a prospective randomized fashion were relatively small and underpowered. Currently, several large controlled randomized studies are underway that will hopefully help physicians make better evidence-based decisions on the timing of tracheostomy. Based on our current knowledge, the following recommendations might be made on a low level of evidence: on day 2 or 3 after onset of mechanical ventilation (>48 h of mechanical ventilation or need for an artificial airway) tracheostomy should be seriously considered. Before decisions are made, several questions should be answered: Is the situation suitable for tracheostomy? Are there relevant contraindications for the performance of a tracheostomy? What is the most likely course of the underlying respiratory insufficiency? What is the likelihood the patient will stay in need of invasive mechanical ventilation for more than a week, either because of an ongoing impairment of oxygenation, weaning failure, upper airway obstruction, coma or a swallowing disorder? If no relevant contraindication is present and if the need for invasive mechanical ventilation can be expected to last for more than one week, tracheostomy should be planned and performed within the next 2 days."],["dc.identifier.isi","000266482100005"],["dc.identifier.pmid","18946428"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/16673"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Edizioni Minerva Medica"],["dc.relation.issn","0375-9393"],["dc.title","Timing of tracheostomy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","708"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Anaesthesia"],["dc.bibliographiccitation.lastpage","713"],["dc.bibliographiccitation.volume","74"],["dc.contributor.author","Perl, T."],["dc.contributor.author","Kunze‐Szikszay, N."],["dc.contributor.author","Bräuer, A."],["dc.contributor.author","Quintel, M."],["dc.contributor.author","Röhrig, A. L."],["dc.contributor.author","Kerpen, K."],["dc.contributor.author","Telgheder, U."],["dc.date.accessioned","2021-06-01T10:47:11Z"],["dc.date.available","2021-06-01T10:47:11Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1111/anae.14601"],["dc.identifier.eissn","1365-2044"],["dc.identifier.issn","0003-2409"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/85512"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.relation.eissn","1365-2044"],["dc.relation.issn","0003-2409"],["dc.title","Aluminium release by coated and uncoated fluid‐warming devices"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","927"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","Artificial Organs"],["dc.bibliographiccitation.lastpage","932"],["dc.bibliographiccitation.volume","37"],["dc.contributor.author","Tirilomis, Theodor"],["dc.contributor.author","Popov, Aron-Frederik"],["dc.contributor.author","Hanekop, Gerd-Gunnar"],["dc.contributor.author","Braeuer, Anselm"],["dc.contributor.author","Quintel, Michael"],["dc.contributor.author","Schoendube, Friedrich Albert"],["dc.contributor.author","Friedrich, Martin G."],["dc.date.accessioned","2018-11-07T09:18:54Z"],["dc.date.available","2018-11-07T09:18:54Z"],["dc.date.issued","2013"],["dc.description.abstract","Renal blood flow (RBF) may vary during cardiopulmonary bypass and low flow may cause insufficient blood supply of the kidney triggering renal failure postoperatively. Still, a valid intraoperative method of continuous RBF measurement is not available. A new catheter combining thermodilution and intravascular Doppler was developed, first calibrated in an in vitro model, and the catheter specific constant was determined. Then, application of the device was evaluated in a pilot study in an adult cardiovascular population. The data of the clinical pilot study revealed high correlation between the flow velocities detected by intravascular Doppler and the RBF measured by thermodilution (Pearson's correlation range: 0.78 to 0.97). In conclusion, the RBF can be measured excellently in real time using the new catheter, even under cardiopulmonary bypass."],["dc.identifier.doi","10.1111/aor.12084"],["dc.identifier.isi","000328325300012"],["dc.identifier.pmid","23635326"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/28509"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1525-1594"],["dc.relation.issn","0160-564X"],["dc.title","A New Device for Intraoperative Renal Blood Flow Measurement During Open-Heart Surgery: An Experimental Study and the Clinical Pilot Study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","687"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","MINERVA ANESTESIOLOGICA"],["dc.bibliographiccitation.lastpage","690"],["dc.bibliographiccitation.volume","74"],["dc.contributor.author","Perl, Tal Naggan"],["dc.contributor.author","Floether, I."],["dc.contributor.author","Weyland, Wolfgang"],["dc.contributor.author","Quintel, M."],["dc.contributor.author","Braeuer, Anselm"],["dc.date.accessioned","2018-11-07T11:08:45Z"],["dc.date.available","2018-11-07T11:08:45Z"],["dc.date.issued","2008"],["dc.description.abstract","Background. Perioperative hypothermia is common during anesthesia and surgery and is accompanied by several complications. Forced-air warming is recognized as an effective procedure to prevent hypothermia. The aim of this study was to compare a resistive hearing device with a forced-air warming device. Methods. Prospective randomized trail, Setting: heat transfer laboratory of a University hospital. Participants: six healthy volunteers. Interventions: warming with a forced-air warming device (BairHugger (TM) 505 and Upper Body Blanket 522; Arizant Healthcare Inc., Eden Prairie, MN, USA) or a resistive heating device (Geratherm Adult system (TM); Geratherm Medical AG, Geschwenda, Germany). Measures: heat transfer was measured with 11 calibrated heat flux transducers on the upper body. Additionally, blanket and skin temperatures were measured. The t-test for matched pairs was used for statistical evaluation. Results. Skin temperature under the covered surface was not statistically different between the two groups (37.3 +/- 0.2 degrees C in the forced-air warming group and 37.8 +/- 0.2 degrees C in the resistive heating group). In contrast, blanket temperature (40.3 +/- 0.6 degrees C vs 38.1 +/- 0.4 degrees C, P=0.002) and heat transfer (13.2 +/- 3.6 W vs 7.8 +/- 1.9 W, P=0.048) were significantly higher in the resistive heating group. Conclusion. Heat transfer in the resisitve heating system was significantly greater than that of the forced-air warming system."],["dc.identifier.isi","000261380000002"],["dc.identifier.pmid","19034247"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/52860"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Edizioni Minerva Medica"],["dc.relation.issn","0375-9393"],["dc.title","Comparison of forced-air warming and resistive heating"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","47"],["dc.bibliographiccitation.journal","Journal of Cardiothoracic Surgery"],["dc.bibliographiccitation.volume","2"],["dc.contributor.author","Heise, Daniel"],["dc.contributor.author","Braeuer, Anselm"],["dc.contributor.author","Quintel, Michael"],["dc.date.accessioned","2018-11-07T11:06:49Z"],["dc.date.available","2018-11-07T11:06:49Z"],["dc.date.issued","2007"],["dc.description.abstract","Postoperative bleeding might become a serious problem in the management of cardiac surgical patients, with marked medical and economic impact. In these life-threatening situations, massive haemorrhage represents frequently a combination of surgical and coagulopathic bleeding. Surgical bleeding results from a definite source at the operation site and can be corrected using surgical standard techniques. Acute coagulopathies, in contrast, result from impaired thrombin formation, and require optimized therapeutical strategies. Effective pharmacological treatment will be complicated by the presence of ventricular assist devices (VAD), which necessarily imply effective anticoagulation. In episodes of uncontrolled coagulopathic bleeding, the application of recombinant activated factor VII (rFVIIa) as a effective haemostatic agent has become more and more popular. However, only very few data are available on its use in patients with VAD in place. We researched the PubMed-database for case reports about the use of rFVIIa in patients with VAD and summarized them. In addition, we report a case from our hospital. In all cases cessation of bleeding without any thrombembolic complications could be achieved. In cases of uncontrollable, non-surgical bleeding rFVIIa seems to be a therapeutical option even for patients with VAD."],["dc.identifier.doi","10.1186/1749-8090-2-47"],["dc.identifier.isi","000205631000047"],["dc.identifier.pmid","17963487"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/52405"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Biomed Central Ltd"],["dc.relation.issn","1749-8090"],["dc.title","Recombinant activated factor VII (Novo7 (R)) in patients with ventricular assist devices: Case report and review of the current literature"],["dc.type","review"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","183"],["dc.bibliographiccitation.journal","CRITICAL CARE"],["dc.bibliographiccitation.volume","19"],["dc.contributor.author","Wetz, Anna J."],["dc.contributor.author","Braeuer, Anselm"],["dc.contributor.author","Quintel, Michael"],["dc.contributor.author","Heise, Daniel"],["dc.date.accessioned","2018-11-07T09:58:22Z"],["dc.date.available","2018-11-07T09:58:22Z"],["dc.date.issued","2015"],["dc.description.abstract","Introduction: Postoperative acute kidney injury (AKI) is a frequently observed phenomenon after cardiac surgery with cardio-pulmonary bypass (CPB); this severe complication is associated with adverse patient outcomes. There are multiple mechanisms involved in AKI during cardiac surgery, including CPB-dependent hemolysis. An IV infusion of sodium bicarbonate, which leads to urine alkalization, may play a role in preventing AKI. Recently, several trials have investigated the effect of sodium bicarbonate and reported controversial results. The purpose of this investigation was to investigate the following question. Under what circumstances can sodium bicarbonate prevent postoperative AKI? Methods: We analyzed data from 342 patients undergoing CPB surgery at the University Hospital Goettingen, Germany. A total of 174 patients received a preemptive dose of sodium bicarbonate. Directly after the induction of anesthesia, the continuous infusion of 0.15 mmol/kg body weight/h was started and continued until 2 pm on the first postoperative day. Patients who were not treated with sodium bicarbonate formed the control group (n = 168). To verify the AKI risk configuration of each group, we surveyed risk factors and determined the commonly used clinical predictive score according to Thakar and colleagues. We recorded the concentration of free hemoglobin (fhb) to estimate the amount of CPB-dependent hemolysis. The definition of AKI was acquired by applying the AKI-network (AKIN) classification over the course of five postoperative days. Results: Patients who received the sodium bicarbonate infusion showed a significantly lower incidence (35.6 vs. 50%) of AKI than that of patients who did not receive the infusion (p = 0.01). AKIN levels 2 and 3 were also more frequent when sodium bicarbonate was not administered. Particularly, in the low-risk cohort (<3 Thakar points), the incidence of AKI was significantly reduced (26 vs. 46%) when patients received sodium bicarbonate (p = 0.01), whereas in the high-risk patients, no significant reduction was observed. Conclusion: In this study, we observed that low-risk patients particularly benefited from the preventive treatment with sodium bicarbonate. The incidence of AKI was significantly reduced in low-risk patients while there was no statistically significant difference in the high-risk patient cohort."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2015"],["dc.identifier.doi","10.1186/s13054-015-0906-9"],["dc.identifier.isi","000356480100001"],["dc.identifier.pmid","25899029"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/13465"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/37351"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Biomed Central Ltd"],["dc.relation.issn","1364-8535"],["dc.relation.issn","1466-609X"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Does sodium bicarbonate infusion really have no effect on the incidence of acute kidney injury after cardiac surgery? A prospective observational trial"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","110"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","The Annals of Thoracic Surgery"],["dc.bibliographiccitation.lastpage","119"],["dc.bibliographiccitation.volume","84"],["dc.contributor.author","Liakopoulos, Oliver Joannis"],["dc.contributor.author","Schmitto, Jan Dieter"],["dc.contributor.author","Kazmaier, Stefan"],["dc.contributor.author","Braeuer, Anselm"],["dc.contributor.author","Quintel, Michael"],["dc.contributor.author","Schoendube, Friedrich Albert"],["dc.contributor.author","Doerge, Hilmar"],["dc.date.accessioned","2018-11-07T11:00:50Z"],["dc.date.available","2018-11-07T11:00:50Z"],["dc.date.issued","2007"],["dc.description.abstract","Background. Cardiopulmonary bypass (CPB)-related inflammatory response can be attenuated by glucocorticoid treatment, but its impact on postoperative cardiopulmonary function remains controversial. It was investigated whether the systemic and myocardial anti-inflammatory effects of glucocorticoids are associated with improved cardiopulmonary function in cardiac surgery patients. Methods. Eighty patients undergoing elective coronary artery bypass grafting were randomly assigned to receive a single shot of methylprednisolone ( 15 mg/kg) or placebo before CPB. Variables of myocardial and pulmonary function and systemic hemodynamics were measured before and 1, 4, 10, and 24 hours after CPB. Blood was sampled for measurement of proinflammatory ( tumor necrosis factor-alpha, interleukin 6, interleukin 8) and antiinflammatory ( interleukin 10) cytokines ( by enzyme-linked immunoassay), troponin T, and C-reactive protein. Phosphorylation of inhibitory kappa-B alpha and p38 mitogen-activated protein kinase was determined in right atrial biopsies before and after CPB ( phosphoprotein assay). Results. Preoperative and intraoperative characteristics of patients were not different between groups. Methylprednisolone attenuated postoperative tumor necrosis factor-alpha, interleukin 6, interleukin 8, and C-reactive protein levels while increasing interleukin 10 release. Myocardial inhibitory kappa-B alpha was preserved with methylprednisolone ( p < 0.05 versus placebo), but p38 mitogen-activated protein kinase activation occurred in both groups after CPB ( p < 0.05 versus before CPB). Methylprednisolone improved postoperative cardiac index and was associated with decreased troponin T when compared with placebo ( p < 0.05). Postoperative blood glucose, oxygen delivery index, and pulmonary shunt flow were increased in the methylprednisolone group ( p < 0.05). There was no difference in postoperative oxygenation index, ventilation time, and clinical outcome between treatment groups. Conclusions. Glucocorticoid treatment before CPB attenuates perioperative release of systemic and myocardial inflammatory mediators and improves myocardial function, suggesting potential cardioprotective effects in patients undergoing cardiac surgery."],["dc.identifier.doi","10.1016/j.athoracsur.2007.01.003"],["dc.identifier.isi","000247373200017"],["dc.identifier.pmid","17588396"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/51018"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.publisher.place","New york"],["dc.relation.conference","43rd Annual Meeting of the Society-of-Thoracic-Surgeons"],["dc.relation.eventlocation","San Diego, CA"],["dc.relation.issn","0003-4975"],["dc.title","Cardiopulmonary and systemic effects of methylprednisolone in patients undergoing cardiac surgery"],["dc.type","conference_paper"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","578"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Acta Anaesthesiologica Scandinavica"],["dc.bibliographiccitation.lastpage","579"],["dc.bibliographiccitation.volume","52"],["dc.contributor.author","Schmitto, Jan Dieter"],["dc.contributor.author","Hein, S."],["dc.contributor.author","Braeuer, Anselm"],["dc.contributor.author","Popov, A. F."],["dc.contributor.author","Quintel, M."],["dc.contributor.author","Schoendube, Friedrich Albert"],["dc.date.accessioned","2018-11-07T11:16:15Z"],["dc.date.available","2018-11-07T11:16:15Z"],["dc.date.issued","2008"],["dc.identifier.doi","10.1111/j.1399-6576.2008.01580.x"],["dc.identifier.isi","000253982900029"],["dc.identifier.pmid","18339175"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/54544"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Blackwell Publishing"],["dc.relation.issn","0001-5172"],["dc.title","Perioperative myocardial infarction after cesarean section in a young woman with hypertrophic obstructive cardiomyopathy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.subtype","letter_note"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","251"],["dc.bibliographiccitation.journal","ANASTHESIOLOGIE & INTENSIVMEDIZIN"],["dc.bibliographiccitation.lastpage","+"],["dc.bibliographiccitation.volume","52"],["dc.contributor.author","Braeuer, Anselm"],["dc.contributor.author","Zink, Wolfgang"],["dc.contributor.author","Timmermann, Arnd"],["dc.contributor.author","Perl, Tal Naggan"],["dc.contributor.author","Quintel, M."],["dc.date.accessioned","2018-11-07T08:57:24Z"],["dc.date.available","2018-11-07T08:57:24Z"],["dc.date.issued","2011"],["dc.description.abstract","In Germany more than 5,000 off-pump coronary artery bypass operations are performed every year. However, peri-operative hypothermia is a common problem during such surgery, and is associated with an adverse patient outcome. A number of measures aimed at preventing pert-operative hypothermia are available. The use of warm-water garments or adhesive hydrogel pads is highly successful and cost effective, although such systems are quite expensive. If this technology is not available a combination of methods should be employed to reduce pen-operative hypothermia. Although of limited efficacy, resistive heating mattresses placed on the body or forced-air warming systems are the best alternative. Adjunctive measures include increasing OR temperature to a level still tolerable for the surgeon, infusion warming with a circulation of at least 2,000 ml, and a heated mattress placed under the back. If a patient has become hypothermic during surgery, active re-warming should be initiated."],["dc.identifier.isi","000289503700002"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/23392"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Aktiv Druck & Verlag Gmbh"],["dc.relation.issn","0170-5334"],["dc.title","Prevention of perioperative hypothermia during off-pump coronary artery bypass surgery"],["dc.type","review"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]