Weiss, Bernhard Gisbert

[["dc.bibliographiccitation.journal","European Archives of Oto-Rhino-Laryngology"],["dc.contributor.author","Spiegel, Jennifer L."],["dc.contributor.author","Jakob, Mark"],["dc.contributor.author","Kruizenga, Marie"],["dc.contributor.author","Freytag, Saskia"],["dc.contributor.author","Bertlich, Mattis"],["dc.contributor.author","Canis, Martin"],["dc.contributor.author","Ihler, Friedrich"],["dc.contributor.author","Haubner, Frank"],["dc.contributor.author","Kitz, Julia"],["dc.contributor.author","Weiss, Bernhard G."],["dc.date.accessioned","2021-04-14T08:32:11Z"],["dc.date.available","2021-04-14T08:32:11Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1007/s00405-020-06389-7"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/83839"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1434-4726"],["dc.relation.issn","0937-4477"],["dc.title","Cancer stem cell markers in adenocarcinoma of the salivary glands - reliable prognostic markers?"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1213"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Otology & Neurotology"],["dc.bibliographiccitation.lastpage","1216"],["dc.bibliographiccitation.volume","38"],["dc.contributor.author","Bertlich, Mattis"],["dc.contributor.author","Ihler, Friedrich"],["dc.contributor.author","Weiss, Bernhard G."],["dc.contributor.author","Freytag, Saskia"],["dc.contributor.author","Jakob, Mark"],["dc.contributor.author","Strupp, Michael"],["dc.contributor.author","Pellkofer, Hannah"],["dc.contributor.author","Canis, Martin"],["dc.date.accessioned","2020-12-10T18:19:57Z"],["dc.date.available","2020-12-10T18:19:57Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1097/MAO.0000000000001510"],["dc.identifier.issn","1531-7129"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/75432"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Fingolimod (FTY-720) is Capable of Reversing Tumor Necrosis Factor Induced Decreases in Cochlear Blood Flow"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","3001"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","European Archives of Oto-Rhino-Laryngology"],["dc.bibliographiccitation.lastpage","3009"],["dc.bibliographiccitation.volume","274"],["dc.contributor.author","Weiss, Bernhard G."],["dc.contributor.author","Bertlich, Mattis"],["dc.contributor.author","Scheele, Rebecka"],["dc.contributor.author","Canis, Martin"],["dc.contributor.author","Jakob, Mark"],["dc.contributor.author","Sohns, Jan M."],["dc.contributor.author","Ihler, Friedrich"],["dc.date.accessioned","2020-12-10T14:10:29Z"],["dc.date.available","2020-12-10T14:10:29Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1007/s00405-017-4609-5"],["dc.identifier.eissn","1434-4726"],["dc.identifier.issn","0937-4477"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/70775"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Systematic radiographic evaluation of three potential implantation sites for a semi-implantable bone conduction device in 52 patients after previous mastoid surgery"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","European Archives of Oto-Rhino-Laryngology"],["dc.contributor.author","Weiss, Bernhard G."],["dc.contributor.author","Anczykowski, Mahalia Zoe"],["dc.contributor.author","Küffer, Stefan"],["dc.contributor.author","Spiegel, Jennifer L."],["dc.contributor.author","Bertlich, Mattis"],["dc.contributor.author","Canis, Martin"],["dc.contributor.author","Ihler, Friedrich"],["dc.contributor.author","Kitz, Julia"],["dc.contributor.author","Jakob, Mark"],["dc.date.accessioned","2021-04-14T08:24:45Z"],["dc.date.available","2021-04-14T08:24:45Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1007/s00405-020-06262-7"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/81414"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1434-4726"],["dc.relation.issn","0937-4477"],["dc.title","Prognostic impact of additional HPV diagnostics in 102 patients with p16-stratified advanced oropharyngeal squamous cell carcinoma"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","The Laryngoscope"],["dc.bibliographiccitation.lastpage","9"],["dc.bibliographiccitation.volume","130"],["dc.contributor.author","Weiss, Bernhard G."],["dc.contributor.author","Anczykowski, Mahalia Z."],["dc.contributor.author","Flach, Susanne"],["dc.contributor.author","Spiegel, Jennifer L."],["dc.contributor.author","Kitz, Julia"],["dc.contributor.author","Bertlich, Mattis"],["dc.contributor.author","Canis, Martin"],["dc.contributor.author","Jakob, Mark"],["dc.contributor.author","Ihler, Friedrich"],["dc.date.accessioned","2020-01-14T09:01:11Z"],["dc.date.accessioned","2021-10-27T13:22:03Z"],["dc.date.available","2020-01-14T09:01:11Z"],["dc.date.available","2021-10-27T13:22:03Z"],["dc.date.issued","2019"],["dc.description.abstract","OBJECTIVES/HYPOTHESIS: Indication for postoperative radiotherapy in patients with locally circumscribed tumors (pT1-pT2) and a single ipsilateral lymph node metastasis (pN1) is debatable. The aim of this study was to evaluate the oncological long-term outcome of patients with pT1-pT2 pN1 squamous cell carcinoma (SCC) of the oral cavity, the oropharynx, and the hypopharynx without extracapsular spread (ECS) after a margin-negative surgical resection, who either received or did not receive postoperative (chemo)radiotherapy. STUDY DESIGN: Retrospective case series. METHODS: The oncological outcome of patients with pT1-pT2 pN1 SCC without ECS was evaluated retrospectively. All patients underwent primary tumor resection that included transoral laser microsurgery and neck dissection at an academic tertiary referral center. RESULTS: Of 65 identified patients treated between 1986 and 2015 (18 oral cavity, 30 oropharynx, 17 hypopharynx), 21 (32%) received postoperative radiotherapy, and 44 (68%) were treated by surgery alone. The group of patients receiving postoperative treatment showed a significantly superior 5-year disease-specific (94.4% vs. 73.2%, P = .029) and recurrence-free survival (85.2% vs. 43.2%, P = .002), as well as a higher local control rate (90.2% vs. 64.9%, P = .042). The overall survival was 71.4% vs. 62.6% (P = .53). The mean follow-up was 80.7 months. CONCLUSIONS: Patients with locally circumscribed carcinomas and a single ipsilateral ECS-negative lymph node metastasis seem to benefit from postoperative radiotherapy. LEVEL OF EVIDENCE: 4 Laryngoscope, 2019."],["dc.identifier.doi","10.1002/lary.28394"],["dc.identifier.eissn","1531-4995"],["dc.identifier.issn","0023-852X"],["dc.identifier.pmid","31837151"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/17078"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/92065"],["dc.language.iso","en"],["dc.notes.intern","Migrated from goescholar"],["dc.relation.eissn","1531-4995"],["dc.relation.issn","1531-4995"],["dc.relation.issn","0023-852X"],["dc.relation.orgunit","Universitätsmedizin Göttingen"],["dc.rights","CC BY-NC 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc/4.0"],["dc.subject.ddc","610"],["dc.title","Benefit of postoperative radiotherapy for early tumors with single ipsilateral lymph node metastasis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","17"],["dc.bibliographiccitation.journal","Life Sciences"],["dc.bibliographiccitation.lastpage","21"],["dc.bibliographiccitation.volume","187"],["dc.contributor.author","Bertlich, Mattis"],["dc.contributor.author","Ihler, Friedrich"],["dc.contributor.author","Weiss, Bernhard G."],["dc.contributor.author","Freytag, Saskia"],["dc.contributor.author","Strupp, Michael"],["dc.contributor.author","Jakob, Mark"],["dc.contributor.author","Canis, Martin"],["dc.date.accessioned","2020-12-10T15:20:17Z"],["dc.date.available","2020-12-10T15:20:17Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1016/j.lfs.2017.08.015"],["dc.identifier.issn","0024-3205"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/72606"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Role of capillary pericytes and precapillary arterioles in the vascular mechanism of betahistine in a guinea pig inner ear model"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","60"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Otology & Neurotology"],["dc.bibliographiccitation.lastpage","67"],["dc.bibliographiccitation.volume","41"],["dc.contributor.author","Spiegel, Jennifer L."],["dc.contributor.author","Kutsch, Luise"],["dc.contributor.author","Jakob, Mark"],["dc.contributor.author","Weiss, Bernhard G."],["dc.contributor.author","Canis, Martin"],["dc.contributor.author","Ihler, Friedrich"],["dc.date.accessioned","2020-12-10T18:19:57Z"],["dc.date.available","2020-12-10T18:19:57Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1097/MAO.0000000000002418"],["dc.identifier.issn","1531-7129"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/75436"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Long-Term Stability and Functional Outcome of an Active Middle Ear Implant Regarding Different Coupling Sites"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","3499"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","Head & Neck"],["dc.bibliographiccitation.lastpage","3515"],["dc.bibliographiccitation.volume","41"],["dc.contributor.author","Jakob, Mark"],["dc.contributor.author","Mattes, Lena M."],["dc.contributor.author","Küffer, Stefan"],["dc.contributor.author","Unger, Kristian"],["dc.contributor.author","Hess, Julia"],["dc.contributor.author","Bertlich, Mattis"],["dc.contributor.author","Haubner, Frank"],["dc.contributor.author","Ihler, Friedrich"],["dc.contributor.author","Canis, Martin"],["dc.contributor.author","Weiss, Bernhard G."],["dc.contributor.author","Kitz, Julia"],["dc.date.accessioned","2020-12-10T14:06:37Z"],["dc.date.available","2020-12-10T14:06:37Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1002/hed.v41.10"],["dc.identifier.eissn","1097-0347"],["dc.identifier.issn","1043-3074"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/69962"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","MicroRNA expression patterns in oral squamous cell carcinoma: hsa‐mir‐99b‐3p and hsa‐mir‐100‐5p as novel prognostic markers for oral cancer"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","3144"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","Head & Neck"],["dc.bibliographiccitation.lastpage","3158"],["dc.bibliographiccitation.volume","41"],["dc.contributor.author","Weiss, Bernhard G."],["dc.contributor.author","Ihler, Friedrich"],["dc.contributor.author","Anczykowski, Mahalia Zoe"],["dc.contributor.author","Bertlich, Mattis"],["dc.contributor.author","Kitz, Julia"],["dc.contributor.author","Steiner, Wolfgang"],["dc.contributor.author","Canis, Martin"],["dc.contributor.author","Jakob, Mark"],["dc.date.accessioned","2020-12-10T14:06:36Z"],["dc.date.available","2020-12-10T14:06:36Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1002/hed.25806"],["dc.identifier.eissn","1097-0347"],["dc.identifier.issn","1043-3074"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/69960"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Transoral laser microsurgery for treatment of oropharyngeal cancer in 368 patients"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","331"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Cancer Biomarkers"],["dc.bibliographiccitation.lastpage","347"],["dc.bibliographiccitation.volume","33"],["dc.contributor.author","Weiss, Bernhard G."],["dc.contributor.author","Anczykowski, Mahalia Zoe"],["dc.contributor.author","Ihler, Friedrich"],["dc.contributor.author","Bertlich, Mattis"],["dc.contributor.author","Spiegel, Jennifer L."],["dc.contributor.author","Haubner, Frank"],["dc.contributor.author","Canis, Martin"],["dc.contributor.author","Küffer, Stefan"],["dc.contributor.author","Hess, Julia"],["dc.contributor.author","Unger, Kristian"],["dc.contributor.author","Jakob, Mark"],["dc.date.accessioned","2022-05-02T08:09:30Z"],["dc.date.available","2022-05-02T08:09:30Z"],["dc.date.issued","2022"],["dc.description.abstract","BACKGROUND: MicroRNAs constitute promising biomarkers. OBJECTIVE: The aim was to investigate diagnostic and prognostic implications of miR-182-5p and miR-205-5p in p16-positive and p16-negative oropharyngeal squamous cell carcinomas (OPSCCs). METHODS: Expression of miR-182-5p, miR-205-5p were determined via quantitative real-time-PCR in fresh frozen tissues of 26 p16-positive, 19 p16-negative OPSCCs and 18 HPV-negative oropharyngeal controls. Associations between miRNA-expression, clinicopathological characteristics and prognosis were analyzed. RESULTS: Higher miR-182-5p expression was associated with significant inferior disease-specific survival for p16-positive OPSCCs (HR = 1.98E+09, 95% CI 0–Inf; P= 0.028) and a similar trend was observed for p16-negative OPSCCs (HR = 1.56E+09, 95% CI 0–Inf; P= 0.051). Higher miR-205-5p expression was associated with an inferior progression-free survival (HR = 4.62, 95% CI 0.98–21.83; P= 0.034) and local control rate (HR = 2.18E+09, 95% CI 0–Inf; P= 0.048) for p16-positive OPSCCs. CONCLUSIONS: Results indicate that miR-182-5p and miR-205-5p can further stratify patients with p16-positive OPSCC into prognostic groups."],["dc.description.abstract","BACKGROUND: MicroRNAs constitute promising biomarkers. OBJECTIVE: The aim was to investigate diagnostic and prognostic implications of miR-182-5p and miR-205-5p in p16-positive and p16-negative oropharyngeal squamous cell carcinomas (OPSCCs). METHODS: Expression of miR-182-5p, miR-205-5p were determined via quantitative real-time-PCR in fresh frozen tissues of 26 p16-positive, 19 p16-negative OPSCCs and 18 HPV-negative oropharyngeal controls. Associations between miRNA-expression, clinicopathological characteristics and prognosis were analyzed. RESULTS: Higher miR-182-5p expression was associated with significant inferior disease-specific survival for p16-positive OPSCCs (HR = 1.98E+09, 95% CI 0–Inf; P= 0.028) and a similar trend was observed for p16-negative OPSCCs (HR = 1.56E+09, 95% CI 0–Inf; P= 0.051). Higher miR-205-5p expression was associated with an inferior progression-free survival (HR = 4.62, 95% CI 0.98–21.83; P= 0.034) and local control rate (HR = 2.18E+09, 95% CI 0–Inf; P= 0.048) for p16-positive OPSCCs. CONCLUSIONS: Results indicate that miR-182-5p and miR-205-5p can further stratify patients with p16-positive OPSCC into prognostic groups."],["dc.identifier.doi","10.3233/CBM-203149"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/107398"],["dc.notes.intern","DOI Import GROB-561"],["dc.relation.eissn","1875-8592"],["dc.relation.issn","1574-0153"],["dc.title","MicroRNA-182-5p and microRNA-205-5p as potential biomarkers for prognostic stratification of p16-positive oropharyngeal squamous cell carcinoma"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]