Sohns, Jan Martin

[["dc.bibliographiccitation.artnumber","433"],["dc.bibliographiccitation.journal","SpringerPlus"],["dc.bibliographiccitation.volume","3"],["dc.contributor.author","Sohns, Jan Martin"],["dc.contributor.author","Fasshauer, Martin"],["dc.contributor.author","Staab, Wieland"],["dc.contributor.author","Steinmetz, Michael"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Unterberg-Buchwald, Christina"],["dc.date.accessioned","2018-11-07T09:36:37Z"],["dc.date.available","2018-11-07T09:36:37Z"],["dc.date.issued","2014"],["dc.description.abstract","Introduction: A 66-years old man suffering from coronary artery disease appeared without symptoms for routine follow-up in our clinic. Case description: The echocardiogram revealed a tumorous mass of the right atrium and right ventricle. In the past, coronary revascularization with venous grafts of the right coronary artery and circumflex artery as well as internal mammaria graft to the left anterior descending artery was performed 20 years before. The general clinicians presented the case to the surgeons and it was decided to perform cardiac MRI as a preoperative diagnostic modality. Discussion and evaluation: Following cardiac magnetic resonance imaging (MRI) showed a mass in the pericardium in the right atrioventricular groove with thrombotic material. Due to the MRI the patient underwent coronary angiography to confirm an aneurysm. Conclusions: The learning points from this case are that cardiac MRI is a very useful tool for further evaluation of suspected cardiac masses and should be performed for further characterization."],["dc.identifier.doi","10.1186/2193-1801-3-433"],["dc.identifier.isi","000359078400004"],["dc.identifier.pmid","25184106"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/10853"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/32660"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","2193-1801"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Giant bypass aneurysm, a cause of suspected cardiac mass"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","218"],["dc.bibliographiccitation.journal","SpringerPlus"],["dc.bibliographiccitation.volume","3"],["dc.contributor.author","Staab, Wieland"],["dc.contributor.author","Goth, Sabrina"],["dc.contributor.author","Sohns, Christian"],["dc.contributor.author","Sohns, Jan Martin"],["dc.contributor.author","Steinmetz, Michael"],["dc.contributor.author","Buchwald, Christina Unterberg"],["dc.contributor.author","Schuster, Andreas"],["dc.contributor.author","Kowallick, Johannes Tammo"],["dc.contributor.author","Fasshauer, Martin"],["dc.contributor.author","Lotz, Joachim"],["dc.date.accessioned","2018-11-07T09:41:07Z"],["dc.date.available","2018-11-07T09:41:07Z"],["dc.date.issued","2014"],["dc.description.abstract","Purpose: Aim of the study was to investigate diagnostic accuracy of cardiac computed tomography angiography (CCTA) between left ventricular end-systolic (LVES) and left ventricular end-diastolic (LVED) cardiac phase for thrombus detection in patient's prior to pulmonary vein isolation (PVI). Materials and methods: 182 consecutive Patients with drug refractory AF scheduled for PVI (62.6% male, mean age 64.1 +/- 10.2 years) underwent routine pre-procedural evaluation including transesophageal echocardiography (TEE) and CCTA for evaluation of left atrial (LA)/left atrial appendage (LAA) anatomy and thrombus formation. Qualitative and quantitative analysis (using aorta ascendens (AA)/LAA ratio) was performed. Measurements of the LA/LAA in LVES and LVED cardiac phase were obtained. Results: End-systolic volumes (LA/LAA) measured in 30 patients without filling defects as control group and all 14 with filling defects of 182 patients were significantly larger (p < 0.01) than in end-diastolic phase. Qualitative analysis was inferior to quantitative analysis using LA/LAA ratio (<0.5; accuracy: 100%, 88%, 100%, 99% vs 100%). 5 out of 182 patients (2.7%) showed thrombus formation of the LAA in CCTA confirmed by TEE and quantitative analysis. Intra/-interobserver variability was lower in end-systolic vs end-diastolic reconstruction interval. Conclusion: For evaluating CCTA datasets in patients prior PVI, the LVES reconstruction interval is recommended due to significantly larger LA/LAA volumes and lower intra/-interobserver variability's."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2014"],["dc.identifier.doi","10.1186/2193-1801-3-218"],["dc.identifier.isi","000359026000005"],["dc.identifier.pmid","25279273"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/11751"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/33654"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","2193-1801"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Comparison of end-diastolic versus end-systolic cardiac-computed tomography reconstruction interval in patient's prior to pulmonary vein isolation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e109164"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","PLoS ONE"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Kowallick, Johannes Tammo"],["dc.contributor.author","Lamata, Pablo"],["dc.contributor.author","Hussain, Shazia T."],["dc.contributor.author","Kutty, Shelby"],["dc.contributor.author","Steinmetz, Michael"],["dc.contributor.author","Sohns, Jan Martin"],["dc.contributor.author","Fasshauer, Martin"],["dc.contributor.author","Staab, Wieland"],["dc.contributor.author","Unterberg-Buchwald, Christina"],["dc.contributor.author","Bigalke, Boris"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Schuster, Andreas"],["dc.date.accessioned","2017-09-07T11:45:27Z"],["dc.date.available","2017-09-07T11:45:27Z"],["dc.date.issued","2014"],["dc.description.abstract","Objectives: Cardiovascular magnetic resonance feature tracking (CMR-FT) offers quantification of myocardial deformation from routine cine images. However, data using CMR-FT to quantify left ventricular (LV) torsion and diastolic recoil are not yet available. We therefore sought to evaluate the feasibility and reproducibility of CMR-FT to quantify LV torsion and peak recoil rate using an optimal anatomical approach. Methods: Short-axis cine stacks were acquired at rest and during dobutamine stimulation (10 and 20 mu g.kg(-1).min(-1)) in 10 healthy volunteers. Rotational displacement was analysed for all slices. A complete 3D-LV rotational model was developed using linear interpolation between adjacent slices. Torsion was defined as the difference between apical and basal rotation, divided by slice distance. Depending on the distance between the most apical (defined as 0% LV distance) and basal (defined as 100% LV distance) slices, four different models for the calculation of torsion were examined: Model-1 (25-75%), Model-2 (0-100%), Model-3 (25-100%) and Model-4 (0-75%). Analysis included subendocardial, subepicardial and global torsion and recoil rate (mean of subendocardial and subepicardial values). Results: Quantification of torsion and recoil rate was feasible in all subjects. There was no significant difference between the different models at rest. However, only Model-1 (25-75%) discriminated between rest and stress (Global Torsion: 2.7 +/- 1.5 degrees cm(-1), 3.6 +/- 2.0 degrees cm(-1), 5.1 +/- 2.2 degrees cm(-1), p<0.01; Global Recoil Rate: -30.1 +/- 11.1 degrees cm(-1) s (-1), -469 +/- 15.0 degrees cm (-1) s (-1), -68.9 +/- 32.3 degrees cm(-1) s(-1), p<0.01; for rest, 10 and 20 mu g.kg(-1).min(-1) of dobutamine, respectively). Reproducibility was sufficient for all parameters as determined by Bland-Altman analysis, intraclass correlation coefficients and coefficient of variation. Conclusions: CMR-FT based derivation of myocardial torsion and recoil rate is feasible and reproducible at rest and with dobutamine stress. Using an optimal anatomical approach measuring rotation at 25% and 75% apical and basal LV locations allows effective quantification of torsion and recoil dynamics. Application of these new measures of deformation by CMR-FT should next be explored in disease states."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2014"],["dc.identifier.doi","10.1371/journal.pone.0109164"],["dc.identifier.gro","3142035"],["dc.identifier.isi","000345743700050"],["dc.identifier.pmid","25285656"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/10994"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/3823"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Public Library Science"],["dc.relation.issn","1932-6203"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Quantification of Left Ventricular Torsion and Diastolic Recoil Using Cardiovascular Magnetic Resonance Myocardial Feature Tracking"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","601"],["dc.bibliographiccitation.journal","SpringerPlus"],["dc.bibliographiccitation.volume","3"],["dc.contributor.author","Sohns, Jan Martin"],["dc.contributor.author","Steinmetz, Michael"],["dc.contributor.author","Schneider, Heike"],["dc.contributor.author","Fasshauer, Martin"],["dc.contributor.author","Staab, Wieland"],["dc.contributor.author","Kowallick, Johannes Tammo"],["dc.contributor.author","Schuster, Andreas"],["dc.contributor.author","Ritter, Christian"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Unterberg-Buchwald, Christina"],["dc.date.accessioned","2018-11-07T09:33:32Z"],["dc.date.available","2018-11-07T09:33:32Z"],["dc.date.issued","2014"],["dc.description.abstract","Introduction: Situs inversus totalis with congenitally corrected transposition of the great arteries represents a relatively rare congenital condition. Case description: The current report describes the case of a 56 year old patient with an atrio-ventricular and ventricular-arterial discordance of the heart chambers without surgical correction, incidentally detected during hepatocellular carcinoma evaluation. The systemic venous blood arrived via the right atrium and a mitral valve in the morphologically left but pulmonary arterial ventricle that gave rise to a pulmonary trunk. The pulmonary venous blood passed the left atrium and the tricuspid valve into a morphologically right but systemic ventricle that gave rise to the aorta. Discussion and evaluation: The switched anatomy was incidentally detected on echocardiography. The patient was referred to cardiac magnetic resonance imaging (CMR) including flow measurements, volumetry and late enhancement. CMR results showed a mildly impaired function and the switched anatomy. During a follow-up period of 2 years the patient was suffering from only mild heart failure and dyspnea. Conclusions: Heart failure symptoms and arrhythmias can appear with increasing age in patients with congenitally corrected transposition. Early CMR allows accurate diagnosis and timely introduction of adequate therapy thereby avoiding disease progression."],["dc.identifier.doi","10.1186/2193-1801-3-601"],["dc.identifier.isi","000359108200001"],["dc.identifier.pmid","25392774"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/11150"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/31986"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","2193-1801"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Situs inversus totalis with congenitally corrected transposition of the great arteries: insights from cardiac MRI"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","655"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Journal of Neurology"],["dc.bibliographiccitation.lastpage","662"],["dc.bibliographiccitation.volume","261"],["dc.contributor.author","Menke, Jan"],["dc.contributor.author","Schramm, Peter"],["dc.contributor.author","Sohns, Jan Martin"],["dc.contributor.author","Kallenberg, Kai"],["dc.contributor.author","Staab, Wieland"],["dc.date.accessioned","2018-11-07T09:41:53Z"],["dc.date.available","2018-11-07T09:41:53Z"],["dc.date.issued","2014"],["dc.description.abstract","This meta-analysis summarizes the accuracy of magnetic resonance angiography (MRA) for diagnosing residuals in coiled cerebral aneurysms by using the threefold Roy classification (residuals: none, neck, or sac). Four databases were searched from 2000 to June 2013 for eligible studies that compared MRA to digital subtraction angiography (DSA) and reported 3 x 3 count data of threefold Roy classification, or a reduced scheme of 2 x 2 count data. Bivariate and trivariate Bayesian random-effects models were used for meta-analysis. Among 27 included studies (2,119 coiled aneurysms in 1,809 patients) the average prevalence of DSA-confirmed sac residuals was 18.2 % (range 0-43 %). The pooled sensitivity was 88.0 % (95 % CI 81.4-94.0) and specificity was 97.2 % (94.6-99.0 %) for assessing sac residuals by MRA. In the trivariate meta-analysis, a \"sac residual\" finding at MRA had a high positive likelihood ratio of 28.2 (14.0-79.0). A \"neck residual\" finding had a moderate negative likelihood ratio of 0.246 (0.111-0.426), and the MRA finding of \"no residual\" had a good negative likelihood ratio of 0.044 (0.013-0.096). Subgroup analyses identified no significant influence of covariates on diagnostic accuracy (P > 0.05). In conclusion, in coiled cerebral aneurysms MRA with application of the threefold Roy classification is well suited for detecting or excluding sac residuals that might require retreatment."],["dc.identifier.doi","10.1007/s00415-013-7053-5"],["dc.identifier.isi","000334177100002"],["dc.identifier.pmid","23893001"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/11666"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/33831"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","Heidelberg"],["dc.relation.issn","1432-1459"],["dc.relation.issn","0340-5354"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Diagnosing flow residuals in coiled cerebral aneurysms by MR angiography: meta-analysis"],["dc.type","review"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","206"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Journal of magnetic resonance imaging : JMRI"],["dc.bibliographiccitation.lastpage","213"],["dc.bibliographiccitation.volume","40"],["dc.contributor.author","Joseph, Arun"],["dc.contributor.author","Kowallick, Johannes T."],["dc.contributor.author","Merboldt, Klaus-Dietmar"],["dc.contributor.author","Voit, Dirk"],["dc.contributor.author","Schaetz, Sebastian"],["dc.contributor.author","Zhang, Shuo"],["dc.contributor.author","Sohns, Jan M."],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Frahm, Jens"],["dc.date.accessioned","2019-07-09T11:41:30Z"],["dc.date.available","2019-07-09T11:41:30Z"],["dc.date.issued","2014-07-01"],["dc.description.abstract","PURPOSE: To evaluate a novel real-time phase-contrast magnetic resonance imaging (MRI) technique for the assessment of through-plane flow in the ascending aorta. MATERIALS AND METHODS: Real-time MRI was based on a radial fast low-angle shot (FLASH) sequence with about 30-fold undersampling and image reconstruction by regularized nonlinear inversion. Phase-contrast maps were obtained from two (interleaved or sequential) acquisitions with and without a bipolar velocity-encoding gradient. Blood flow in the ascending aorta was studied in 10 healthy volunteers at 3 T by both real-time MRI (15 sec during free breathing) and electrocardiogram (ECG)-synchronized cine MRI (with and without breath holding). Flow velocities and stroke volumes were evaluated using standard postprocessing software. RESULTS: The total acquisition time for a pair of phase-contrast images was 40.0 msec (TR/TE = 2.86/1.93 msec, 10° flip angle, 7 spokes per image) for a nominal in-plane resolution of 1.3 mm and a section thickness of 6 mm. Quantitative evaluations of spatially averaged flow velocities and stroke volumes were comparable for real-time and cine methods when real-time MRI data were averaged across heartbeats. For individual heartbeats real-time phase-contrast MRI resulted in higher peak velocities for values above 120 cm s(-1). CONCLUSION: Real-time phase-contrast MRI of blood flow in the human aorta yields functional parameters for individual heartbeats. When averaged across heartbeats real-time flow velocities and stroke volumes are comparable to values obtained by conventional cine MRI."],["dc.identifier.doi","10.1002/jmri.24328"],["dc.identifier.fs","605197"],["dc.identifier.pmid","24123295"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/12139"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/58445"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","1522-2586"],["dc.rights","CC BY-NC 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc/4.0"],["dc.subject.mesh","Adult"],["dc.subject.mesh","Algorithms"],["dc.subject.mesh","Aorta"],["dc.subject.mesh","Blood Flow Velocity"],["dc.subject.mesh","Computer Systems"],["dc.subject.mesh","Humans"],["dc.subject.mesh","Image Enhancement"],["dc.subject.mesh","Image Interpretation, Computer-Assisted"],["dc.subject.mesh","Magnetic Resonance Angiography"],["dc.subject.mesh","Magnetic Resonance Imaging, Cine"],["dc.subject.mesh","Male"],["dc.subject.mesh","Reproducibility of Results"],["dc.subject.mesh","Rheology"],["dc.subject.mesh","Sensitivity and Specificity"],["dc.subject.mesh","Young Adult"],["dc.title","Real-time flow MRI of the aorta at a resolution of 40 msec."],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","997"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","Journal of physical therapy science"],["dc.bibliographiccitation.lastpage","1002"],["dc.bibliographiccitation.volume","26"],["dc.contributor.author","Staab, Wieland"],["dc.contributor.author","Hottowitz, Ralf"],["dc.contributor.author","Sohns, Christian"],["dc.contributor.author","Sohns, Jan Martin"],["dc.contributor.author","Gilbert, Fabian"],["dc.contributor.author","Menke, Jan"],["dc.contributor.author","Niklas, Andree"],["dc.contributor.author","Lotz, Joachim"],["dc.date.accessioned","2021-11-22T14:31:27Z"],["dc.date.available","2021-11-22T14:31:27Z"],["dc.date.issued","2014-07-01"],["dc.description.abstract","[Purpose] A wide variety of accelerometer tools are used to estimate human movement, but there are no adequate data relating to gait symmetry parameters in the context of knee osteoarthritis. This study's purpose was to evaluate a 3D-kinematic system using body-mounted sensors (gyroscopes and accelerometers) on the trunk and limbs. This is the first study to use spectral analysis for data post processing. [Subjects] Twelve patients with unilateral knee osteoarthritis (OA) (10 male) and seven age-matched controls (6 male) were studied. [Methods] Measurements with 3-D accelerometers and gyroscopes were compared to video analysis with marker positions tracked by a six-camera optoelectronic system (VICON 460, Oxford Metrics). Data were recorded using the 3D-kinematic system. [Results] The results of both gait analysis systems were significantly correlated. Five parameters were significantly different between the knee OA and control groups. To overcome time spent in expensive post-processing routines, spectral analysis was performed for fast differentiation between normal gait and pathological gait signals using the 3D-kinematic system. [Conclusions] The 3D-kinematic system is objective, inexpensive, accurate and portable, and allows long-term recordings in clinical, sport as well as ergonomic or functional capacity evaluation (FCE) settings. For fast post-processing, spectral analysis of the recorded data is recommended."],["dc.identifier.doi","10.1589/jpts.26.997"],["dc.identifier.fs","608275"],["dc.identifier.isi","000339626700010"],["dc.identifier.pmid","25140082"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/10645"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/93379"],["dc.language","eng"],["dc.language.iso","en"],["dc.notes.intern","Migrated from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Soc Physical Therapy Science"],["dc.relation.issn","0915-5287"],["dc.relation.issn","2187-5626"],["dc.rights","CC BY-NC-ND 3.0"],["dc.rights.access","openAccess"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc-nd/3.0"],["dc.subject","Accelerometer; Gait; Gyroscope"],["dc.title","Accelerometer and gyroscope based gait analysis using spectral analysis of patients with osteoarthritis of the knee."],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","60"],["dc.bibliographiccitation.journal","Journal of Cardiovascular Magnetic Resonance"],["dc.bibliographiccitation.volume","16"],["dc.contributor.author","Kowallick, Johannes Tammo"],["dc.contributor.author","Kutty, Shelby"],["dc.contributor.author","Edelmann, Frank"],["dc.contributor.author","Chiribiri, Amedeo"],["dc.contributor.author","Villa, Adriana"],["dc.contributor.author","Steinmetz, Michael"],["dc.contributor.author","Sohns, Jan Martin"],["dc.contributor.author","Staab, Wieland"],["dc.contributor.author","Bettencourt, Nuno"],["dc.contributor.author","Unterberg-Buchwald, Christina"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Schuster, Andreas"],["dc.date.accessioned","2017-09-07T11:45:39Z"],["dc.date.available","2017-09-07T11:45:39Z"],["dc.date.issued","2014"],["dc.description.abstract","Background: Cardiovascular Magnetic Resonance myocardial feature tracking (CMR-FT) is a quantitative technique tracking tissue voxel motion on standard steady-state free precession (SSFP) cine images to assess ventricular myocardial deformation. The importance of left atrial (LA) deformation assessment is increasingly recognized and can be assessed with echocardiographic speckle tracking. However atrial deformation quantification has never previously been demonstrated with CMR. We sought to determine the feasibility and reproducibility of CMR-FT for quantitative derivation of LA strain and strain rate (SR) myocardial mechanics. Methods: 10 healthy volunteers, 10 patients with hypertrophic cardiomyopathy (HCM) and 10 patients with heart failure and preserved ejection fraction (HFpEF) were studied at 1.5 Tesla. LA longitudinal strain and SR parameters were derived from SSFP cine images using dedicated CMR-FT software (2D CPA MR, TomTec, Germany). LA performance was analyzed using 4- and 2-chamber views including LA reservoir function (total strain [epsilon(s)], peak positive SR [SRs]), LA conduit function (passive strain [epsilon(e)], peak early negative SR [SRe]) and LA booster pump function (active strain [epsilon(a)], late peak negative SR [SRa]). Results: In all subjects LA strain and SR parameters could be derived from SSFP images. There was impaired LA reservoir function in HCM and HFpEF (epsilon(s) [%]: HCM 22.1 +/- 5.5, HFpEF 16.3 +/- 5.8, Controls 29.1 +/- 5.3, p < 0.01; SRs [s(-1)]: HCM 0.9 +/- 0.2, HFpEF 0.8 +/- 0.3, Controls 1.1 +/- 0.2, p < 0.05) and impaired LA conduit function as compared to healthy controls (epsilon(e) [%]: HCM 10.4 +/- 3.9, HFpEF 11.9 +/- 4.0, Controls 21.3 +/- 5.1, p < 0.001; SRe [s(-1)]: HCM -0.5 +/- 0.2, HFpEF -0.6 +/- 0.1, Controls -1.0 +/- 0.3, p < 0.01). LA booster pump function was increased in HCM while decreased in HFpEF (epsilon(a) [%]: HCM 11.7 +/- 4.0, HFpEF 4.5 +/- 2.9, Controls 7.8 +/- 2.5, p < 0.01; SRa [s(-1)]: HCM -1.2 +/- 0.4, HFpEF -0.5 +/- 0.2, Controls -0.9 +/- 0.3, p < 0.01). Observer variability was excellent for all strain and SR parameters on an intra- and inter-observer level as determined by Bland-Altman, coefficient of variation and intraclass correlation coefficient analyses. Conclusions: CMR-FT based atrial performance analysis reliably quantifies LA longitudinal strain and SR from standard SSFP cine images and discriminates between patients with impaired left ventricular relaxation and healthy controls. CMR-FT derived atrial deformation quantification seems a promising novel approach for the study of atrial performance and physiology in health and disease states."],["dc.identifier.doi","10.1186/s12968-014-0060-6"],["dc.identifier.gro","3142077"],["dc.identifier.isi","000341846700001"],["dc.identifier.pmid","25196447"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/10814"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/4289"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Biomed Central Ltd"],["dc.relation.eissn","1532-429X"],["dc.relation.issn","1097-6647"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Quantification of left atrial strain and strain rate using Cardiovascular Magnetic Resonance myocardial feature tracking: a feasibility study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1"],["dc.bibliographiccitation.journal","IJC Heart & Vasculature"],["dc.bibliographiccitation.lastpage","7"],["dc.bibliographiccitation.volume","10"],["dc.contributor.author","Kowallick, Johannes Tammo"],["dc.contributor.author","Steinmetz, Michael"],["dc.contributor.author","Schuster, Andreas"],["dc.contributor.author","Unterberg-Buchwald, Christina"],["dc.contributor.author","Nguyen, Thuy-Trang"],["dc.contributor.author","Fasshauer, Martin"],["dc.contributor.author","Staab, Wieland"],["dc.contributor.author","Hösch, Olga"],["dc.contributor.author","Rosenberg, Christina"],["dc.contributor.author","Paul, Thomas"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Sohns, Jan Martin"],["dc.date.accessioned","2019-07-09T11:42:04Z"],["dc.date.available","2019-07-09T11:42:04Z"],["dc.date.issued","2016"],["dc.description.abstract","Aim To compare estimated pressure gradients from routine follow-up cardiovascular phase-contrast magnetic resonance (PC-MR) with those from Doppler echocardiography and invasive catheterization in patients with congenital heart disease (CHD) and pulmonary outflow tract obstruction. Methods In 75 patients with pulmonary outflow tract obstruction maximal and mean PC-MR gradients were compared to maximal and mean Doppler gradients. Additionally, in a subgroup of 31 patients maximal and mean PC-MR and Doppler pressure gradients were compared to catheter peak-to-peak pressure gradients (PPG). Results Maximal and mean PC-MR gradients underestimated pulmonary outflow tract obstruction as compared to Doppler (max gradient: bias = + 8.4 mm Hg (+ 47.6%), r = 0.89, p < 0.001; mean gradient: + 4.3 mm Hg (+ 49.0%), r = 0.88, p < 0.001). However, in comparison to catheter PPG, maximal PC-MR gradients (bias = + 1.8 mm Hg (+ 8.8%), r = 0.90, p = 0.14) and mean Doppler gradients (bias = − 2.3 mm Hg (− 11.2%), r = 0.87, p = 0.17) revealed best agreement. Mean PC-MR gradients underestimated (bias = − 7.7 mm Hg (− 55.6%), r = 0.90, p < 0.001) while maximal Doppler gradients systematically overestimated catheter PPG (bias = + 13.9 mm Hg (+ 56.5%), r = 0.88, p < 0.001). Conclusions Estimated maximal PC-MR pressure gradients from routine CHD follow-up agree well with invasively assessed peak-to-peak pressure gradients. Estimated maximal Doppler pressure gradients tend to overestimate, while Doppler mean gradients agree better with catheter PPG. Therefore, our data provide reasonable arguments to either apply maximal PC-MR gradients or mean Doppler gradients to non-invasively evaluate the severity of pulmonary outflow tract obstruction in the follow-up of CHD."],["dc.identifier.doi","10.1016/j.ijcha.2015.11.001"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/12765"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/58581"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","2352-9067"],["dc.rights","CC BY-NC-ND 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc-nd/4.0"],["dc.title","Non-invasive estimation of pulmonary outflow tract obstruction: A comparative study of cardiovascular phase contrast magnetic resonance and Doppler echocardiography versus cardiac catheterization"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","E91"],["dc.bibliographiccitation.firstpage","E91-1"],["dc.bibliographiccitation.issue","Suppl 1"],["dc.bibliographiccitation.journal","Journal of Cardiovascular Magnetic Resonance"],["dc.bibliographiccitation.lastpage","E91-2"],["dc.bibliographiccitation.volume","15"],["dc.contributor.author","Steinmetz, Michael"],["dc.contributor.author","Sohns, Jan M."],["dc.contributor.author","Schulte, Christina"],["dc.contributor.author","Preuss, Christoph H."],["dc.contributor.author","Zapf, Antonia"],["dc.contributor.author","Staab, Wieland"],["dc.contributor.author","Kowallick, Johannes T."],["dc.contributor.author","Unterberg-Buchwald, Christina"],["dc.contributor.author","Paul, Thomas"],["dc.contributor.author","Lotz, Joachim"],["dc.date.accessioned","2013-04-17T07:14:16Z"],["dc.date.accessioned","2021-10-27T13:20:01Z"],["dc.date.available","2013-04-17T07:14:16Z"],["dc.date.available","2021-10-27T13:20:01Z"],["dc.date.issued","2013"],["dc.description.abstract","Patients with corrected Tetralogy of Fallot (cTOF) can develop supraventricular arrhythmias. So far, right atrial (RA) volume in TOF has not been evaluated in the context of arrhythmia. The aim of this study was to evaluate if right atrial (RA) volume in TOF correlates with the occurrence of supraventricular arrhythmias. To identify other risk factors for arrhythmias additional parameters were included in the analysis: anthropomorphic parameters (BMI, age, gender), previous shunt, high right ventricular (RV) volumes and pulmonary regurgitation (PR)."],["dc.identifier.doi","10.1186/1532-429X-15-S1-E91"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/8914"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/91930"],["dc.language.iso","en"],["dc.notes.intern","Migrated from goescholar"],["dc.relation.issn","1532-429X"],["dc.relation.orgunit","Universitätsmedizin Göttingen"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Right atrial volume and body mass index in corrected tetralogy of Fallot correlate with the incidence of supraventricular arrhythmia - an MRI study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]