Kauffels-Sprenger, Anne

[["dc.bibliographiccitation.firstpage","2039"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Clinical Oral Investigations"],["dc.bibliographiccitation.lastpage","2045"],["dc.bibliographiccitation.volume","22"],["dc.contributor.author","Schmalz, Gerhard"],["dc.contributor.author","Meisel, Anja"],["dc.contributor.author","Kollmar, Otto"],["dc.contributor.author","Kauffels, Anne"],["dc.contributor.author","Slotta, Jan E."],["dc.contributor.author","Kottmann, Tanja"],["dc.contributor.author","Haak, Rainer"],["dc.contributor.author","Ziebolz, Dirk"],["dc.date.accessioned","2021-06-01T10:49:16Z"],["dc.date.available","2021-06-01T10:49:16Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1007/s00784-017-2298-5"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/86222"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.relation.eissn","1436-3771"],["dc.relation.issn","1432-6981"],["dc.title","Oral health-related quality of life depending on dental and periodontal health in different patients before and after liver transplantation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Transplantation Journal"],["dc.bibliographiccitation.volume","99"],["dc.contributor.author","Slotta, Jan Erik"],["dc.contributor.author","Kauffels, Anne"],["dc.contributor.author","Gruenhage, Frank"],["dc.contributor.author","Lammert, Frank"],["dc.contributor.author","Kollmar, Otto"],["dc.date.accessioned","2018-11-07T09:54:49Z"],["dc.date.available","2018-11-07T09:54:49Z"],["dc.date.issued","2015"],["dc.format.extent","302"],["dc.identifier.isi","000368626500745"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/36614"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Lippincott Williams & Wilkins"],["dc.publisher.place","Philadelphia"],["dc.relation.conference","21st Annual International Congress of the International-Liver-Transplant-Society (ILTS)"],["dc.relation.eventlocation","Chicago, IL"],["dc.relation.issn","1534-6080"],["dc.relation.issn","0041-1337"],["dc.title","Outcome After Marginal Donor Liver Transplantation at a Low-Volume Center"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","745"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Clinical Oral Investigations"],["dc.bibliographiccitation.lastpage","752"],["dc.bibliographiccitation.volume","21"],["dc.contributor.author","Ziebolz, Dirk"],["dc.contributor.author","Schmalz, Gerhard"],["dc.contributor.author","Kauffels, Anne"],["dc.contributor.author","Widmer, Florian"],["dc.contributor.author","Widmer, Katja"],["dc.contributor.author","Slotta, Jan Erik"],["dc.contributor.author","Mausberg, Rainer F."],["dc.contributor.author","Kollmar, Otto"],["dc.date.accessioned","2018-11-07T10:25:33Z"],["dc.date.available","2018-11-07T10:25:33Z"],["dc.date.issued","2017"],["dc.description.abstract","The aim of this single-center cross-sectional study was to detect the prevalence of selected periodontal pathogenic bacteria and active matrix metalloproteinase-8 (aMMP-8) level in patients before (preLTx) and after liver transplantation (postLTx). Periodontal pocket depth (PPD) and clinical attachment loss (CAL) were assessed. Subgingival biofilm samples were analyzed using polymerase chain reaction (PCR) to detect 11 common periodontal pathogens. Gingival crevicular fluid (GCF) samples were analyzed with enzyme-linked immunosorbent assay (ELISA) to determine aMMP-8 level and assigned to a scoring system: score 0: 0-8 ng/ml, score 1: 8-20 ng/ml, and score 2: > 20 ng/ml. The following were used for the statistical analysis: t test, Mann-Whitney U test, Fishers test (alpha = 5 %). In total, 110 patients (preLTx: n = 35, postLTx: n = 75) could be included in the study. Periodontal findings were not significantly different between groups. In microbiological analysis, a significantly higher prevalence of Campylobacter rectus in preLTx group was detected (p = 0.03). Significantly more patients with score 0 in postLTx group (p = 0.024) and significantly more patients with score 1 in preLTx group were found (p = 0.004). Furthermore, aMMP-8 concentrations for patients with moderate periodontitis were significantly lower in postLTx group compared to preLTx group (p = 0.045). Additionally, in postLTx group, aMMP-8 concentration was significantly higher in patients with severe periodontitis compared to those with no/mild periodontitis (p = 0.016). LTx appears to affect aMMP-8 level, but not bacterial findings in patients after LTx. Determination of aMMP-8 level in patients after LTx with immunosuppressive medication might lead to wrong interpretation of the results."],["dc.identifier.doi","10.1007/s00784-016-1821-4"],["dc.identifier.isi","000398710700003"],["dc.identifier.pmid","27074844"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/42876"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Springer"],["dc.publisher.place","Heidelberg"],["dc.relation.issn","1436-3771"],["dc.relation.issn","1432-6981"],["dc.title","Periodontal pathogenic bacteria and aMMP-8 findings depending on periodontal conditions of patients before and after liver transplantation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","72"],["dc.bibliographiccitation.journal","BMC Oral Health"],["dc.bibliographiccitation.volume","16"],["dc.contributor.author","Schmalz, Gerhard"],["dc.contributor.author","Kauffels, Anne"],["dc.contributor.author","Kollmar, Otto"],["dc.contributor.author","Slotta, Jan Erik"],["dc.contributor.author","Vasko, Radovan"],["dc.contributor.author","Mueller, Georg Anton"],["dc.contributor.author","Haak, Rainer"],["dc.contributor.author","Ziebolz, Dirk"],["dc.date.accessioned","2018-11-07T10:10:08Z"],["dc.date.available","2018-11-07T10:10:08Z"],["dc.date.issued","2016"],["dc.description.abstract","Background: Aim of this single center cross-sectional study was to investigate oral behavior, dental, periodontal and microbiological findings in patients undergoing hemodialysis (HD) and after kidney transplantation (KT). Methods: Patients undergoing HD for end-stage renal failure and after KT were investigated. Oral health behavior was recorded using a standardized questionnaire, e.g. dental behavior, tooth brushing, oral hygiene aids. Oral investigation included screening of oral mucosa, dental findings (DMF-T) and periodontal situation (Papilla bleeding index [PBI] periodontal probing depth [PPD] and clinical attachment loss [CAL]). Additionally, microbiological analysis of subgingival biofilm samples (PCR) was performed. Statistical analysis: Student's t-test or Mann-Whitney-U-test, Fisher's exact test (a = 5 %). Results: A total of 70 patients (HD: n = 35, KT: n = 35) with a mean age of 56.4 +/- 11.1 (HD) and 55.8 +/- 10.9 (KT) years were included. Lack in use of additional oral hygiene (dental floss, inter-dental brush) was found. KT group presented significantly more gingivial overgrowth (p = 0.01). DMF-T was 19.47 +/- 5.84 (HD) and 17.61 +/- 5.81 (KT; p = 0. 21). Majority of patients had clinically moderate and severe periodontitis; showing a need for periodontal treatment of 57 % (HD) and 71 % (KT; p = 0.30). Significantly higher prevalence of Parvimonas micra and Capnocytophaga species in the HD group were found (p < 0.01). Conclusion: Periodontal treatment need and lack in oral behavior for both groups indicate the necessity of an improved early treatment and prevention of dental and periodontal disease, e.g. in form of special care programs. Regarding microbiological findings, no major differences between KT and HD patients were found."],["dc.identifier.doi","10.1186/s12903-016-0274-0"],["dc.identifier.isi","000381734000003"],["dc.identifier.pmid","27531498"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/13871"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/39797"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Biomed Central Ltd"],["dc.relation.issn","1472-6831"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Oral behavior, dental, periodontal and microbiological findings in patients undergoing hemodialysis and after kidney transplantation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Transplantation Journal"],["dc.bibliographiccitation.volume","99"],["dc.contributor.author","Kauffels, Anne"],["dc.contributor.author","Kollmar, Otto"],["dc.contributor.author","Widmer, Florian"],["dc.contributor.author","Bader, Oliver"],["dc.contributor.author","Ziebolz, Dirk"],["dc.contributor.author","Slotta, Jan Erik"],["dc.date.accessioned","2018-11-07T09:54:47Z"],["dc.date.available","2018-11-07T09:54:47Z"],["dc.date.issued","2015"],["dc.format.extent","150"],["dc.identifier.isi","000368626500212"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/36611"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Lippincott Williams & Wilkins"],["dc.publisher.place","Philadelphia"],["dc.relation.conference","21st Annual International Congress of the International-Liver-Transplant-Society (ILTS)"],["dc.relation.eventlocation","Chicago, IL"],["dc.relation.issn","1534-6080"],["dc.relation.issn","0041-1337"],["dc.title","Influence of Immunosuppressive Medication After Liver Transplantation On Oral Health, Periodontitis and Dental Status-A Cross-Sectional Study"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","244"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","International Dental Journal"],["dc.bibliographiccitation.lastpage","251"],["dc.bibliographiccitation.volume","67"],["dc.contributor.author","Kauffels, Anne"],["dc.contributor.author","Schmalz, Gerhard"],["dc.contributor.author","Kollmar, Otto"],["dc.contributor.author","Slotta, Jan E."],["dc.contributor.author","Weig, Michael"],["dc.contributor.author","Groß, Uwe"],["dc.contributor.author","Bader, Oliver"],["dc.contributor.author","Ziebolz, Dirk"],["dc.date.accessioned","2020-12-10T18:28:50Z"],["dc.date.available","2020-12-10T18:28:50Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1111/idj.12290"],["dc.identifier.issn","0020-6539"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/76426"],["dc.language.iso","fr"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Oral findings and dental behaviour before and after liver transplantation – a single-centre cross-sectional study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","409"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","JOURNAL OF CARDIOVASCULAR SURGERY"],["dc.bibliographiccitation.lastpage","415"],["dc.bibliographiccitation.volume","56"],["dc.contributor.author","Shayesteh-Kheslat, R."],["dc.contributor.author","Kauffels, Anne"],["dc.contributor.author","Rubie, C."],["dc.contributor.author","Frick, V. O."],["dc.contributor.author","Wagner, M."],["dc.contributor.author","Kollmar, Otto"],["dc.contributor.author","Schilling, Martin Karl"],["dc.date.accessioned","2018-11-07T09:56:41Z"],["dc.date.available","2018-11-07T09:56:41Z"],["dc.date.issued","2015"],["dc.description.abstract","Aim. Stenotic peripheral and dilatative arteriosclerotic diseases have different pathomechanism although associations between both diseases are well known. The adhesion molecule MUC18 is a cell membrane glycoprotein also known as the melanoma cell adhesion molecule. As MUC18 has proangiogenic potency in melanoma and prostate cancer this study investigated the role of MUC18 in patients with stenotic or dilatative arteriosclerotic disease as a putative biochemical marker. Methods. Using qRT-PCR, Western Blot and immunohistochemistry techniques, the expression of MUC18 in arteriosclerotic arteries from major lower limb amputates (AP, N.=15) as well as specimen from femoral endarterectomies (TEA, N.=20) and in dilatative aortic diseases using abdominal aortic aneurysms (AAA, N.=13) was evaluated. Human visceral arteries without macroscopic arteriosclerosis from liver transplants served as controls (AN, N.=19). Results. MUC18 mRNA and protein expression could be found in AN, AP, TEA and AAA tissues. Immunohistochemical analysis showed that a complete and intact intima was the predominant location of MUC18 expression. Although in stenotic arteriosclerotic disease (AP and TEA) the intima was widely calcified, qRT-PCR analysis showed overexpression compared to normal tissue. Interestingly, MUC18 expression was significantly down-regulated in dilatative compared to stenotic arteriosclerotic disease and normal arteries. Conclusion. In peripheral stenotic arteriosclerotic disease the proangiogenic potency of MUC18 may play a role in angiogenesis of collaterals, whereas in dilatative aortic diseases the induction of collaterals is typically not evident. The results support the hypothesis of a role in angiogenesis of MUC18 in stenotic arteriosclerotic disease."],["dc.identifier.isi","000355362400011"],["dc.identifier.pmid","25729916"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/37013"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Edizioni Minerva Medica"],["dc.relation.issn","1827-191X"],["dc.relation.issn","0021-9509"],["dc.title","Proangiogenic potency of MUC18 in arteriosclerotic disease"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]