Schneider, Heike E.

[["dc.bibliographiccitation.journal","Journal of Interventional Cardiac Electrophysiology"],["dc.contributor.author","Krause, Ulrich"],["dc.contributor.author","Müller, Matthias J."],["dc.contributor.author","Schneider, Heike E."],["dc.contributor.author","Paul, Thomas"],["dc.date.accessioned","2022-05-02T08:09:42Z"],["dc.date.available","2022-05-02T08:09:42Z"],["dc.date.issued","2022"],["dc.description.abstract","Abstract Background Prevalence of atrial fibrillation (AF) is increasing in adult patients with congenital heart disease (CHD). Experience using the cryoballoon to achieve pulmonary vein isolation (PVI) in adult CHD patients is limited. The aim of the present study was to assess the value of PVI by cryoballoon in adult CHD patients and to evaluate the significance of additional radiofrequency (RF) ablation of atrial tachycardia (AT). Patients and methods Prospective data analysis; all patients with CHD and AF and PVI using the cryoballoon from January 2017 through November 2021 were included. Results Nineteen patients with various types of CHD were included. Median age was 58 (IQR 47–63) years. A total of 12/19 (63%) patients had had RF ablation of right atrial AT before. Median procedure duration was 225 (IQR 196–261) min. Median fluoroscopy time was 12.3 (IQR 5.2–19.5) min and median freeze time was 32 (IQR 28–36.3) min. Procedural success was achieved in all patients. Additional RF catheter ablation of intraatrial reentrant tachycardia within the left atrium was performed in 3/19 (16%) subjects and within the right atrium in 6/19 (32%) patients. Median follow-up was 26 (IQR 9–49) months. Excluding a 90-day blanking period, recurrence of AF was observed in 6/19 subjects (32%). After one redo procedure deploying RF energy only, 84% of all patients remained free from recurrence. Phrenic nerve palsy was observed in 1 subject. Conclusion Results after PVI using the cryoballoon plus additional RF ablation of AT were promising (84% success including one redo procedure). Success of AF ablation was unsatisfactory in all patients who had no additional AT ablation. Ablation of any AT in these patients should therefore be considered in addition to PVI."],["dc.description.abstract","Abstract Background Prevalence of atrial fibrillation (AF) is increasing in adult patients with congenital heart disease (CHD). Experience using the cryoballoon to achieve pulmonary vein isolation (PVI) in adult CHD patients is limited. The aim of the present study was to assess the value of PVI by cryoballoon in adult CHD patients and to evaluate the significance of additional radiofrequency (RF) ablation of atrial tachycardia (AT). Patients and methods Prospective data analysis; all patients with CHD and AF and PVI using the cryoballoon from January 2017 through November 2021 were included. Results Nineteen patients with various types of CHD were included. Median age was 58 (IQR 47–63) years. A total of 12/19 (63%) patients had had RF ablation of right atrial AT before. Median procedure duration was 225 (IQR 196–261) min. Median fluoroscopy time was 12.3 (IQR 5.2–19.5) min and median freeze time was 32 (IQR 28–36.3) min. Procedural success was achieved in all patients. Additional RF catheter ablation of intraatrial reentrant tachycardia within the left atrium was performed in 3/19 (16%) subjects and within the right atrium in 6/19 (32%) patients. Median follow-up was 26 (IQR 9–49) months. Excluding a 90-day blanking period, recurrence of AF was observed in 6/19 subjects (32%). After one redo procedure deploying RF energy only, 84% of all patients remained free from recurrence. Phrenic nerve palsy was observed in 1 subject. Conclusion Results after PVI using the cryoballoon plus additional RF ablation of AT were promising (84% success including one redo procedure). Success of AF ablation was unsatisfactory in all patients who had no additional AT ablation. Ablation of any AT in these patients should therefore be considered in addition to PVI."],["dc.description.sponsorship","Georg-August-Universität Göttingen"],["dc.identifier.doi","10.1007/s10840-022-01213-0"],["dc.identifier.pii","1213"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/107443"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-561"],["dc.relation.eissn","1572-8595"],["dc.relation.issn","1383-875X"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Catheter ablation of atrial fibrillation using 2nd-generation cryoballoon in congenital heart disease patients — significance of RF ablation of additional atrial macro-reentrant tachycardia"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","33"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Clinical Research in Cardiology"],["dc.bibliographiccitation.lastpage","42"],["dc.bibliographiccitation.volume","102"],["dc.contributor.author","Schneider, Heike E."],["dc.contributor.author","Steinmetz, Michael"],["dc.contributor.author","Krause, Ulrich J."],["dc.contributor.author","Kriebel, Thomas"],["dc.contributor.author","Ruschewski, Wolfgang"],["dc.contributor.author","Paul, Thomas"],["dc.date.accessioned","2018-11-07T09:30:45Z"],["dc.date.available","2018-11-07T09:30:45Z"],["dc.date.issued","2013"],["dc.description.abstract","Left cardiac sympathetic denervation (LCSD) may be a therapeutic adjunct for young patients with catecholaminergic polymorphic ventricular tachycardia (CPVT) and long QT syndrome (LQTS) who are not fully protected by beta-blockade. The objective of this analysis was to report our institutional experience with LSCD in young patients for the management of life-threatening ventricular arrhythmias in CPVT and LQTS. Ten young patients with CPVT and LQTS underwent transaxillary LSCD at our institution. Mean age at surgery was 14.0 (range 3.9-42) years, mean body weight was 45.7 (range 15.5-90) kg. Five patients had the clinical diagnosis of CPVT, three were genotype positive for a mutation in the ryanodine-receptor-2-gene. Four of five LQTS patients were genotype positive. Indications for LCSD were recurrent syncope, symptomatic episodes of ventricular tachycardias and/or internal cardioverter-defibrillator (ICD) discharges, and aborted cardiac arrest despite high doses of beta-blockers. LCSD was performed via the transaxillary approach. No significant complications were observed. Two patients already had an ICD, 6 patients received an ICD at the same operation or shortly thereafter. Median length of follow-up after LCSD was 2.3 (range 0.6-3.9) years. After LCSD a marked reduction in arrhythmia burden and cardiac events was observed in all patients while medication was continued. None of the patients had any further ICD discharge for sustained VT. After LCSD, arrhythmia burden could significantly be reduced in all our young patients with CPVT and LQTS."],["dc.identifier.doi","10.1007/s00392-012-0492-7"],["dc.identifier.isi","000313070900004"],["dc.identifier.pmid","22821214"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/8805"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/31382"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","Heidelberg"],["dc.relation.issn","1861-0684"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Left cardiac sympathetic denervation for the management of life-threatening ventricular tachyarrhythmias in young patients with catecholaminergic polymorphic ventricular tachycardia and long QT syndrome"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","179"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Klinische Pädiatrie"],["dc.bibliographiccitation.lastpage","182"],["dc.bibliographiccitation.volume","224"],["dc.contributor.author","Krause, Ulrich J."],["dc.contributor.author","Schneider, Heike E."],["dc.contributor.author","Webel, Martin"],["dc.contributor.author","Paul, Thomas"],["dc.date.accessioned","2018-11-07T09:10:35Z"],["dc.date.available","2018-11-07T09:10:35Z"],["dc.date.issued","2012"],["dc.description.abstract","Background: Aortic thrombosis is rarely observed in neonates and infants. Underlying conditions include the presence of umbilical artery catheters, thrombosed aneurysm of the ductus arteriosus, sepsis and different states of inherited thrombophilia. Treatment options include anticoagulation, thrombolytic therapy and thrombectomy. Due to the lack of large studies, neither diagnosis nor treatment of neonatal aortic thrombosis are standardized. Patients: From 2008-2010, 1 neonate and 1 infant were admitted to our hospital with symptomatic aortic thrombosis. Methods and Results: In both patients, diagnosis was made by Doppler ultrasound. Both patients were effectively treated with recombinant tissuetype plasminogen activator. Diagnosis and treatment of 2 infants with symptomatic aortic thrombosis are discussed and the literature is reviewed. Conclusions: Since aortic thrombosis is a life-threatening condition, early diagnosis by Doppler ultrasound is mandatory to initiate treatment without delay. Thrombolytic therapy is a safe measure to treat this condition if administered with caution and if the patient has not suffered from serious complications such as mesenteric infarction or renal failure prior to begin of therapy."],["dc.identifier.doi","10.1055/s-0031-1295421"],["dc.identifier.isi","000305171500013"],["dc.identifier.pmid","22377739"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/26525"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Georg Thieme Verlag Kg"],["dc.relation.issn","0300-8630"],["dc.title","Thrombosis of the Aorta Abdominalis in Infants - Diagnosis and Thrombolytic Therapy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","292"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Catheterization and Cardiovascular Interventions"],["dc.bibliographiccitation.lastpage","295"],["dc.bibliographiccitation.volume","91"],["dc.contributor.author","Schneider, Heike E."],["dc.contributor.author","Gravenhorst, Verena"],["dc.contributor.author","Paul, Thomas"],["dc.contributor.author","Jacobshagen, Claudius"],["dc.date.accessioned","2021-06-01T10:49:45Z"],["dc.date.available","2021-06-01T10:49:45Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1002/ccd.27445"],["dc.identifier.issn","1522-1946"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/86404"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.relation.issn","1522-1946"],["dc.title","Insufficiency of a Damus-Kaye-Stansel anastomosis in a Fontan patient: Transfemoral implantation of an Edwards Sapien 3 valve"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","459"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Pediatric Cardiology"],["dc.bibliographiccitation.lastpage","464"],["dc.bibliographiccitation.volume","37"],["dc.contributor.author","Dieks, Jana-Katharina"],["dc.contributor.author","Mueller, Matthias J."],["dc.contributor.author","Schneider, Heike E."],["dc.contributor.author","Krause, Ulrich J."],["dc.contributor.author","Steinmetz, Michael"],["dc.contributor.author","Paul, Thomas"],["dc.contributor.author","Kriebel, Thomas"],["dc.date.accessioned","2018-11-07T10:17:25Z"],["dc.date.available","2018-11-07T10:17:25Z"],["dc.date.issued","2016"],["dc.description.abstract","Experience of catheter ablation of pediatric focal atrial tachycardia (FAT) is still limited. There are data which were gathered prior to the introduction of modern 3D mapping and navigation systems into the clinical routine. Accordingly, procedures were associated with significant fluoroscopy and low success rates. The aim of this study was to present clinical and electrophysiological details of catheter ablation of pediatric FAT using modern mapping systems. Since March 2003, 17 consecutive patients < 20 years underwent electrophysiological study (EPS) for FAT using the NavX(A (R)) system (n = 7), the non-contact mapping system (n = 6) or the LocaLisa(A (R)) system (n = 4), respectively. Radiofrequency was the primary energy source; cryoablation was performed in selected patients with a focus close to the AV node. In 16 patients, a total number of 19 atrial foci (right-sided n = 13, left-sided n = 6) could be targeted. In the remaining patient, FAT was not present/inducible during EPS. On an intention-to-treat basis, acute success was achieved in 14/16 patients (87.5 %) with a median number of 11 (1-31) energy applications. Ablation was unsuccessful in two patients due to an epicardial location of a right atrial focus (n = 1) and a focus close to the His bundle (n = 1), respectively. Median procedure time was 210 (84-332) min, and median fluoroscopy time was 13.1 (4.5-22.5) min. In pediatric patients with FAT, 3D mapping and catheter ablation provided improved clinical quality of care. Catheter ablation may be considered early in the course of treatment of this tachyarrhythmia in symptomatic patients."],["dc.identifier.doi","10.1007/s00246-015-1299-x"],["dc.identifier.isi","000373308800004"],["dc.identifier.pmid","26538211"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/41220"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","1432-1971"],["dc.relation.issn","0172-0643"],["dc.title","Catheter Ablation of Pediatric Focal Atrial Tachycardia: Ten-Year Experience Using Modern Mapping Systems"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","European Journal of Pediatrics"],["dc.bibliographiccitation.volume","170"],["dc.contributor.author","Schneider, Heike E."],["dc.contributor.author","Kriebel, TA"],["dc.contributor.author","Schill, Manfred"],["dc.contributor.author","Stahl, M."],["dc.contributor.author","Paul, Thomas"],["dc.date.accessioned","2018-11-07T08:59:28Z"],["dc.date.available","2018-11-07T08:59:28Z"],["dc.date.issued","2011"],["dc.format.extent","270"],["dc.identifier.isi","000286334200053"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/23905"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","New york"],["dc.relation.issn","0340-6199"],["dc.title","Intracoronary ultrasound and selective coronary artery angiography early and late after a new modified cryoenergy application at growing myocardium"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","663"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Pediatric Cardiology"],["dc.bibliographiccitation.lastpage","668"],["dc.bibliographiccitation.volume","38"],["dc.contributor.author","Krause, Ulrich"],["dc.contributor.author","Abreu da Cunha, Filipe D."],["dc.contributor.author","Backhoff, David"],["dc.contributor.author","Jacobshagen, Claudius"],["dc.contributor.author","Klehs, Sophia"],["dc.contributor.author","Schneider, Heike E."],["dc.contributor.author","Paul, Thomas"],["dc.date.accessioned","2018-11-07T10:25:38Z"],["dc.date.available","2018-11-07T10:25:38Z"],["dc.date.issued","2017"],["dc.description.abstract","To improve long-term outcome after cryoablation of substrates of supraventricular tachycardia, application of two and three consecutive freeze-thaw cycles has been performed. The effect of triple freeze-thaw cycles on lesion formation within developing myocardium and coronary arteries, however, has not been studied yet. In eight piglets (mean age 15 weeks, weight 15-20 kg), 30 cryolesions (three consecutive freeze-thaw cycles) were applied to the atrial aspect of both AV valve annuli (n = 18) as well as to ventricular myocardium below the valves (n = 12). Coronary angiography was performed before and after cryoenergy application. The animals were reevaluated by coronary angiography and intracoronary ultrasound (ICUS) after 48 h. All hearts were removed for histological examination of the lesions subsequently. After staining (hematoxylin-eosin, desmin immunohistochemistry), lesions was measured by planimetry with a digital virtual miscroscope analysis system and volumes of the cryolesions were calculated. Mean atrial lesion volume was 190.68 +/- 167.53 mm(3) (n = 18), and mean ventricular lesion volume was 184.34 +/- 107.42 mm(3) (n = 12). Compared with previously reported data on lesion volumes after single and double freeze-thaw cycles, lesions were significantly larger. Coronary arteries were unaffected on coronary angiography as well as on ICUS. No affection of coronary arteries was found on histological examination. Application of three consecutive freeze-thaw cycles resulted in increased lesion volume compared with single and double freeze-thaw cycles. No affection of the coronary arteries was evident. To evaluate the clinical benefit and safety of triple cryoenergy application for catheter ablation, prospective randomized trials are required."],["dc.identifier.doi","10.1007/s00246-016-1564-7"],["dc.identifier.isi","000399219800004"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/42893"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.relation.issn","1432-1971"],["dc.relation.issn","0172-0643"],["dc.title","Effects of Triple Cryoenergy Application on Lesion Formation and Coronary Arteries in the Developing Myocardium"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","701"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Journal of Cardiovascular Electrophysiology"],["dc.bibliographiccitation.lastpage","707"],["dc.bibliographiccitation.volume","24"],["dc.contributor.author","Schneider, Heike E."],["dc.contributor.author","Stahl, Maja"],["dc.contributor.author","Kriebel, Thomas"],["dc.contributor.author","Schillinger, Wolfgang"],["dc.contributor.author","Schill, Manfred"],["dc.contributor.author","Jakobi, Johannes"],["dc.contributor.author","Paul, Thomas"],["dc.date.accessioned","2018-11-07T09:24:09Z"],["dc.date.available","2018-11-07T09:24:09Z"],["dc.date.issued","2013"],["dc.description.abstract","Modified Cryoenergy at Growing Myocardium Introduction Data on radiofrequency current application (RFA) at growing myocardium suggest that coronary artery stenosis may occur with a low incidence. Cryoenergy has emerged as an effective alternative to RFA. Although already used in clinical practice, experience with cryoenergy is low due to lack of data concerning effects of a modified double cryoenergy application, a freeze-thaw-freeze cycle, at growing myocardium. Purpose of the study was to assess lesion volume (efficacy) and risk of coronary artery damage (safety) early, 48hours, after modified double cryoenergy application in a piglet model. Methods and Results In 5 piglets, following selective coronary angiography, two sequential cycles of cryoenergy were delivered at -75 degrees C for 4 minutes, interrupted by thawing for one minute, at the atrioventricular groove. Piglets were restudied after 48hours by coronary angiography and intracoronary ultrasound (ICUS). Ablation lesions were examined morphologically and lesion volume was determined by 3-dimensional morphometric analysis. Lesion volume was 109.21 +/- 39.61mm3 for atrial and 150.30 +/- 53.21mm3 (P= 0.02) for ventricular lesions. Lesion depth was not significantly different for atrial, 3.07 +/- 1.08mm, versus ventricular lesions, 3.56 +/- 1.3mm. Cryoenergy induced minor coronary artery damage with medial and adventitial necrosis but a preserved intimal layer was present in 2/31 lesions, which had not been detected by coronary angiography or ICUS. Conclusion Early after double cryoenergy application, subclinical minor changes of the coronary artery wall could be detected occasionally whereas the intimal layer remained intact. These findings may have implications on efficacy and safety when cryoenergy is applied for tachycardia substrates in pediatric patients."],["dc.description.sponsorship","German Heart Foundation/German Foundation of Heart Research"],["dc.identifier.doi","10.1111/jce.12085"],["dc.identifier.isi","000319898500016"],["dc.identifier.pmid","23470208"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/29751"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1045-3873"],["dc.title","Double Cryoenergy Application (Freeze-Thaw-Freeze) at Growing Myocardium: Lesion Volume and Effects on Coronary Arteries Early After Energy Application. Implications for Efficacy and Safety in Pediatric Patients"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","361"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Pediatric Cardiology"],["dc.bibliographiccitation.lastpage","369"],["dc.bibliographiccitation.volume","42"],["dc.contributor.author","Dieks, Jana-K."],["dc.contributor.author","Backhoff, David"],["dc.contributor.author","Schneider, Heike E."],["dc.contributor.author","Müller, Matthias J."],["dc.contributor.author","Krause, Ulrich"],["dc.contributor.author","Paul, Thomas"],["dc.date.accessioned","2021-04-14T08:32:13Z"],["dc.date.available","2021-04-14T08:32:13Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1007/s00246-020-02491-z"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/83848"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1432-1971"],["dc.relation.issn","0172-0643"],["dc.title","Lone Atrial Flutter in Children and Adolescents: Is It Really “Lone”?"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","Clinical Research in Cardiology"],["dc.bibliographiccitation.volume","100"],["dc.contributor.author","Schneider, Heike E."],["dc.contributor.author","Kriebel, TA"],["dc.contributor.author","Steinmetz, M."],["dc.contributor.author","Ruschewski, Wolfgang"],["dc.contributor.author","Paul, Thomas"],["dc.date.accessioned","2018-11-07T08:52:34Z"],["dc.date.available","2018-11-07T08:52:34Z"],["dc.date.issued","2011"],["dc.format.extent","823"],["dc.identifier.isi","000294690900032"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/22198"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","Heidelberg"],["dc.relation.issn","1861-0684"],["dc.title","Left cardiac sympathetic denervation for the management of life-threatening ventricular tachyarrhythmias in young patients with catecholaminergic polymorphic ventricular tachycardia and long QT syndrome"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]