Schneider, Heike E.

[["dc.bibliographiccitation.firstpage","33"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Clinical Research in Cardiology"],["dc.bibliographiccitation.lastpage","42"],["dc.bibliographiccitation.volume","102"],["dc.contributor.author","Schneider, Heike E."],["dc.contributor.author","Steinmetz, Michael"],["dc.contributor.author","Krause, Ulrich J."],["dc.contributor.author","Kriebel, Thomas"],["dc.contributor.author","Ruschewski, Wolfgang"],["dc.contributor.author","Paul, Thomas"],["dc.date.accessioned","2018-11-07T09:30:45Z"],["dc.date.available","2018-11-07T09:30:45Z"],["dc.date.issued","2013"],["dc.description.abstract","Left cardiac sympathetic denervation (LCSD) may be a therapeutic adjunct for young patients with catecholaminergic polymorphic ventricular tachycardia (CPVT) and long QT syndrome (LQTS) who are not fully protected by beta-blockade. The objective of this analysis was to report our institutional experience with LSCD in young patients for the management of life-threatening ventricular arrhythmias in CPVT and LQTS. Ten young patients with CPVT and LQTS underwent transaxillary LSCD at our institution. Mean age at surgery was 14.0 (range 3.9-42) years, mean body weight was 45.7 (range 15.5-90) kg. Five patients had the clinical diagnosis of CPVT, three were genotype positive for a mutation in the ryanodine-receptor-2-gene. Four of five LQTS patients were genotype positive. Indications for LCSD were recurrent syncope, symptomatic episodes of ventricular tachycardias and/or internal cardioverter-defibrillator (ICD) discharges, and aborted cardiac arrest despite high doses of beta-blockers. LCSD was performed via the transaxillary approach. No significant complications were observed. Two patients already had an ICD, 6 patients received an ICD at the same operation or shortly thereafter. Median length of follow-up after LCSD was 2.3 (range 0.6-3.9) years. After LCSD a marked reduction in arrhythmia burden and cardiac events was observed in all patients while medication was continued. None of the patients had any further ICD discharge for sustained VT. After LCSD, arrhythmia burden could significantly be reduced in all our young patients with CPVT and LQTS."],["dc.identifier.doi","10.1007/s00392-012-0492-7"],["dc.identifier.isi","000313070900004"],["dc.identifier.pmid","22821214"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/8805"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/31382"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","Heidelberg"],["dc.relation.issn","1861-0684"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Left cardiac sympathetic denervation for the management of life-threatening ventricular tachyarrhythmias in young patients with catecholaminergic polymorphic ventricular tachycardia and long QT syndrome"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","731"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Heart Rhythm"],["dc.bibliographiccitation.lastpage","739"],["dc.bibliographiccitation.volume","7"],["dc.contributor.author","Schneider, Heike E."],["dc.contributor.author","Kriebel, Thomas"],["dc.contributor.author","Jung, Klaus"],["dc.contributor.author","Gravenhorst, Verena D."],["dc.contributor.author","Paul, Thomas"],["dc.date.accessioned","2018-11-07T08:42:45Z"],["dc.date.available","2018-11-07T08:42:45Z"],["dc.date.issued","2010"],["dc.description.abstract","BACKGROUND Idiopathic ventricular tachycardia (VT) in children with a structurally normal heart can cause significant morbidity, and although rare, mortality. Conventional activation and pace mapping may be limited by nonsustained tachycardia or unstable hemodynamics. OBJECTIVE The aim of this study was to assess feasibility of catheter ablation of idiopathic VT in the pediatric population guided by noncontact mapping. METHODS Twenty consecutive pediatric patients with idiopathic VT underwent electrophysiologic study with the intention to use the noncontact mapping system EnSite 3000 (EnSite Array, St. Jude Medical Inc., Minneapolis, Minnesota). The multielectrode balloon array was introduced into the left or right ventricle, respectively, and tachycardia was analyzed using color-coded isopotential maps as well as reconstructed unipolar electrograms on the virtual geometry. The region of origin was identified in all of them, and the site of earliest activation with a QS pattern of the unipolar electrograms was guided for sites of ablation. RESULTS Idiopathic VT originated from the right ventricular outflow tract in 6 patients, from the left ventricle in 8, and from the aortic sinus cusp in 6 in this cohort with a median age of 14.4 (range: 4.8 to 20.9) years. Ablation was attempted in 18 of 20 children, and was acutely successful in 17 of these 18 (94%). During a mean follow-up of 2.3 +/- 1.7 years, VT recurred in 3, 2 of them have been treated with a second procedure, resulting in an overall intermediate-term success in 16 of 18 (89%) children with idiopathic VT. CONCLUSION Noncontact mapping can safely and effectively be used to map and guide catheter ablation of the tachycardia substrate of idiopathic VT in pediatric patients."],["dc.identifier.doi","10.1016/j.hrthm.2010.02.031"],["dc.identifier.isi","000278608300002"],["dc.identifier.pmid","20193776"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6219"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/19771"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.relation.issn","1547-5271"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Catheter ablation of idiopathic left and right ventricular tachycardias in the pediatric population using noncontact mapping"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1197"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","Pacing and Clinical Electrophysiology"],["dc.bibliographiccitation.lastpage","1202"],["dc.bibliographiccitation.volume","32"],["dc.contributor.author","Kriebel, Thomas"],["dc.contributor.author","Hermann, Hans-Peter"],["dc.contributor.author","Schneider, Heike"],["dc.contributor.author","Kroll, Maja"],["dc.contributor.author","Selle, Jakob"],["dc.contributor.author","Overwaul, Anna"],["dc.contributor.author","Sigler, Matthias"],["dc.contributor.author","Paul, Thomas"],["dc.date.accessioned","2021-11-22T14:31:49Z"],["dc.date.available","2021-11-22T14:31:49Z"],["dc.date.issued","2009"],["dc.description.abstract","BACKGROUND: Animal studies and clinical observations have demonstrated that radiofrequency current application at growing myocardium may result in coronary artery obstruction. Recently, cryoenergy has emerged as an effective alternative to radiofrequency ablation of arrhythmogenic substrates in pediatric patients. Up to now, there has been a lack of experimental data concerning the effects of cryoenergy application at growing myocardium. METHODS: During general anesthesia, selective coronary angiography of the right and left coronary artery was performed in 10 piglets (age: 6 weeks, body weight: 14-18 kg). Subsequently, cryoenergy was delivered at -75 degrees C for 4 minutes using a 7-F catheter with a 6-mm-tip electrode at the atrial aspect of the tricuspid valve annulus in a posterior and lateral position. Additional cryoenergy lesions were induced via a retrograde approach at the lateral and posterior atrial and ventricular aspect of the mitral valve annulus, respectively. Five animals were restudied after 48 hours by coronary angiography and intracoronary ultrasound and in the remaining five piglets after 3 and 6 months, respectively. RESULTS: Selective coronary angiography and intracoronary ultrasound studies did not demonstrate any evidence for coronary artery obstruction after 48 hours, 3 months, or 6 months after cryoenergy application. In addition, histological examinations of the cryolesions after 48 hours and after 6 months did not demonstrate any intimal proliferations of the coronary arteries, respectively. CONCLUSIONS: By means of the present study, we did not observe any affection of the coronary arteries after cryoenergy application at growing myocardium in young piglets."],["dc.description.abstract","Methods: During general anesthesia, selective coronary angiography of the right and left coronary artery was performed in 10 piglets (age: 6 weeks, body weight: 14-18 kg). Subsequently, cryoenergy was delivered at -75 degrees C for 4 minutes using a 7-F catheter with a 6-mm-tip electrode at the atrial aspect of the tricuspid valve annulus in a posterior and lateral position. Additional cryoenergy lesions were induced via a retrograde approach at the lateral and posterior atrial and ventricular aspect of the mitral valve annulus, respectively. Five animals were restudied after 48 hours by coronary angiography and intracoronary ultrasound and in the remaining five piglets after 3 and 6 months, respectively. Results: Selective coronary angiography and intracoronary ultrasound studies did not demonstrate any evidence for coronary artery obstruction after 48 hours, 3 months, or 6 months after cryoenergy application. In addition, histological examinations of the cryolesions after 48 hours and after 6 months did not demonstrate any intimal proliferations of the coronary arteries, respectively. Conclusions: By means of the present study, we did not observe any affection of the coronary arteries after cryoenergy application at growing myocardium in young piglets. (PACE 2009; 32:1197-1202)."],["dc.identifier.doi","10.1111/j.1540-8159.2009.02465.x"],["dc.identifier.isi","000269390500015"],["dc.identifier.pmid","19719499"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6288"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/93405"],["dc.language.iso","en"],["dc.notes.intern","Migrated from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell Publishing, Inc"],["dc.relation.issn","1540-8159"],["dc.rights.access","closedAccess"],["dc.subject.ddc","610"],["dc.subject.mesh","Animals"],["dc.subject.mesh","Coronary Artery Disease"],["dc.subject.mesh","Coronary Stenosis"],["dc.subject.mesh","Coronary Vessels"],["dc.subject.mesh","Cryosurgery"],["dc.subject.mesh","Risk Assessment"],["dc.subject.mesh","Swine"],["dc.title","Cryoablation at growing myocardium: no evidence of coronary artery obstruction or intimal plaque formation early and late after energy application."],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","461"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Heart Rhythm"],["dc.bibliographiccitation.lastpage","467"],["dc.bibliographiccitation.volume","6"],["dc.contributor.author","Schneider, Heike E."],["dc.contributor.author","Kriebel, Thomas"],["dc.contributor.author","Gravenhorst, Verena D."],["dc.contributor.author","Paul, Thomas"],["dc.date.accessioned","2018-11-07T08:31:06Z"],["dc.date.available","2018-11-07T08:31:06Z"],["dc.date.issued","2009"],["dc.description.abstract","BACKGROUND Several case reports have documented coronary artery stenosis or even occlusion after radiofrequency energy ablation (RFA) in children and adults. Coronary involvement early and (ate after RFA has also been described in animal models. OBJECTIVE The purpose of this study was to assess prospectively the incidence of coronary artery injury early after catheter ablation for supraventricular tachycardias (SVT) in children. METHODS From October 2002 to January 2008, 212 consecutive patients younger than 21. years with SVT underwent selective coronary angiography before and 30 minutes after RFA or cryoablation. RESULTS Median patient age was 12 years (range 0.3-20.4 years), and median body weight was 47 kg (range 5.5-130 kg). An accessory pathway was diagnosed in 112 patients, AV nodal reentrant tachycardia (AVNRT) in 84 patients, and both an accessory pathway and AVNRT in 16 patients. Congenital heart disease was present in 31 patients. In 2 of 117 patients who had RFA for an accessory pathway, an acute reduction in luminal diameter of the coronary artery adjacent to the ablation site was observed. These two patients with a structurally normal heart showed ST-segment changes with normalization of the ECG within 1 week. Both were clinically asymptomatic, and two-dimensional echocardiography documented normal ventricular function. Noninvasive testing did not reveal any evidence of persistent myocardial ischemia. No coronary artery damage was noted after ablation for AVNRT or after ablation with cryoenergy. CONCLUSION Coronary artery narrowing adjacent to the RFA site was noted in 2 of 117 patients with an accessory pathway and occurred only in patients with a posteroseptal pathway. Coronary angiography could be helpful in avoiding coronary lesions in these settings."],["dc.identifier.doi","10.1016/j.hrthm.2009.01.029"],["dc.identifier.isi","000264919500004"],["dc.identifier.pmid","19324303"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6217"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/17044"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.relation.issn","1547-5271"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Incidence of coronary artery injury immediately after catheter ablation for supraventricular tachycardias in infants and children"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]