Schneider, Heike E.

[["dc.bibliographiccitation.firstpage","33"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Clinical Research in Cardiology"],["dc.bibliographiccitation.lastpage","42"],["dc.bibliographiccitation.volume","102"],["dc.contributor.author","Schneider, Heike E."],["dc.contributor.author","Steinmetz, Michael"],["dc.contributor.author","Krause, Ulrich J."],["dc.contributor.author","Kriebel, Thomas"],["dc.contributor.author","Ruschewski, Wolfgang"],["dc.contributor.author","Paul, Thomas"],["dc.date.accessioned","2018-11-07T09:30:45Z"],["dc.date.available","2018-11-07T09:30:45Z"],["dc.date.issued","2013"],["dc.description.abstract","Left cardiac sympathetic denervation (LCSD) may be a therapeutic adjunct for young patients with catecholaminergic polymorphic ventricular tachycardia (CPVT) and long QT syndrome (LQTS) who are not fully protected by beta-blockade. The objective of this analysis was to report our institutional experience with LSCD in young patients for the management of life-threatening ventricular arrhythmias in CPVT and LQTS. Ten young patients with CPVT and LQTS underwent transaxillary LSCD at our institution. Mean age at surgery was 14.0 (range 3.9-42) years, mean body weight was 45.7 (range 15.5-90) kg. Five patients had the clinical diagnosis of CPVT, three were genotype positive for a mutation in the ryanodine-receptor-2-gene. Four of five LQTS patients were genotype positive. Indications for LCSD were recurrent syncope, symptomatic episodes of ventricular tachycardias and/or internal cardioverter-defibrillator (ICD) discharges, and aborted cardiac arrest despite high doses of beta-blockers. LCSD was performed via the transaxillary approach. No significant complications were observed. Two patients already had an ICD, 6 patients received an ICD at the same operation or shortly thereafter. Median length of follow-up after LCSD was 2.3 (range 0.6-3.9) years. After LCSD a marked reduction in arrhythmia burden and cardiac events was observed in all patients while medication was continued. None of the patients had any further ICD discharge for sustained VT. After LCSD, arrhythmia burden could significantly be reduced in all our young patients with CPVT and LQTS."],["dc.identifier.doi","10.1007/s00392-012-0492-7"],["dc.identifier.isi","000313070900004"],["dc.identifier.pmid","22821214"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/8805"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/31382"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","Heidelberg"],["dc.relation.issn","1861-0684"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Left cardiac sympathetic denervation for the management of life-threatening ventricular tachyarrhythmias in young patients with catecholaminergic polymorphic ventricular tachycardia and long QT syndrome"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","459"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Pediatric Cardiology"],["dc.bibliographiccitation.lastpage","464"],["dc.bibliographiccitation.volume","37"],["dc.contributor.author","Dieks, Jana-Katharina"],["dc.contributor.author","Mueller, Matthias J."],["dc.contributor.author","Schneider, Heike E."],["dc.contributor.author","Krause, Ulrich J."],["dc.contributor.author","Steinmetz, Michael"],["dc.contributor.author","Paul, Thomas"],["dc.contributor.author","Kriebel, Thomas"],["dc.date.accessioned","2018-11-07T10:17:25Z"],["dc.date.available","2018-11-07T10:17:25Z"],["dc.date.issued","2016"],["dc.description.abstract","Experience of catheter ablation of pediatric focal atrial tachycardia (FAT) is still limited. There are data which were gathered prior to the introduction of modern 3D mapping and navigation systems into the clinical routine. Accordingly, procedures were associated with significant fluoroscopy and low success rates. The aim of this study was to present clinical and electrophysiological details of catheter ablation of pediatric FAT using modern mapping systems. Since March 2003, 17 consecutive patients < 20 years underwent electrophysiological study (EPS) for FAT using the NavX(A (R)) system (n = 7), the non-contact mapping system (n = 6) or the LocaLisa(A (R)) system (n = 4), respectively. Radiofrequency was the primary energy source; cryoablation was performed in selected patients with a focus close to the AV node. In 16 patients, a total number of 19 atrial foci (right-sided n = 13, left-sided n = 6) could be targeted. In the remaining patient, FAT was not present/inducible during EPS. On an intention-to-treat basis, acute success was achieved in 14/16 patients (87.5 %) with a median number of 11 (1-31) energy applications. Ablation was unsuccessful in two patients due to an epicardial location of a right atrial focus (n = 1) and a focus close to the His bundle (n = 1), respectively. Median procedure time was 210 (84-332) min, and median fluoroscopy time was 13.1 (4.5-22.5) min. In pediatric patients with FAT, 3D mapping and catheter ablation provided improved clinical quality of care. Catheter ablation may be considered early in the course of treatment of this tachyarrhythmia in symptomatic patients."],["dc.identifier.doi","10.1007/s00246-015-1299-x"],["dc.identifier.isi","000373308800004"],["dc.identifier.pmid","26538211"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/41220"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","1432-1971"],["dc.relation.issn","0172-0643"],["dc.title","Catheter Ablation of Pediatric Focal Atrial Tachycardia: Ten-Year Experience Using Modern Mapping Systems"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","701"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Journal of Cardiovascular Electrophysiology"],["dc.bibliographiccitation.lastpage","707"],["dc.bibliographiccitation.volume","24"],["dc.contributor.author","Schneider, Heike E."],["dc.contributor.author","Stahl, Maja"],["dc.contributor.author","Kriebel, Thomas"],["dc.contributor.author","Schillinger, Wolfgang"],["dc.contributor.author","Schill, Manfred"],["dc.contributor.author","Jakobi, Johannes"],["dc.contributor.author","Paul, Thomas"],["dc.date.accessioned","2018-11-07T09:24:09Z"],["dc.date.available","2018-11-07T09:24:09Z"],["dc.date.issued","2013"],["dc.description.abstract","Modified Cryoenergy at Growing Myocardium Introduction Data on radiofrequency current application (RFA) at growing myocardium suggest that coronary artery stenosis may occur with a low incidence. Cryoenergy has emerged as an effective alternative to RFA. Although already used in clinical practice, experience with cryoenergy is low due to lack of data concerning effects of a modified double cryoenergy application, a freeze-thaw-freeze cycle, at growing myocardium. Purpose of the study was to assess lesion volume (efficacy) and risk of coronary artery damage (safety) early, 48hours, after modified double cryoenergy application in a piglet model. Methods and Results In 5 piglets, following selective coronary angiography, two sequential cycles of cryoenergy were delivered at -75 degrees C for 4 minutes, interrupted by thawing for one minute, at the atrioventricular groove. Piglets were restudied after 48hours by coronary angiography and intracoronary ultrasound (ICUS). Ablation lesions were examined morphologically and lesion volume was determined by 3-dimensional morphometric analysis. Lesion volume was 109.21 +/- 39.61mm3 for atrial and 150.30 +/- 53.21mm3 (P= 0.02) for ventricular lesions. Lesion depth was not significantly different for atrial, 3.07 +/- 1.08mm, versus ventricular lesions, 3.56 +/- 1.3mm. Cryoenergy induced minor coronary artery damage with medial and adventitial necrosis but a preserved intimal layer was present in 2/31 lesions, which had not been detected by coronary angiography or ICUS. Conclusion Early after double cryoenergy application, subclinical minor changes of the coronary artery wall could be detected occasionally whereas the intimal layer remained intact. These findings may have implications on efficacy and safety when cryoenergy is applied for tachycardia substrates in pediatric patients."],["dc.description.sponsorship","German Heart Foundation/German Foundation of Heart Research"],["dc.identifier.doi","10.1111/jce.12085"],["dc.identifier.isi","000319898500016"],["dc.identifier.pmid","23470208"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/29751"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1045-3873"],["dc.title","Double Cryoenergy Application (Freeze-Thaw-Freeze) at Growing Myocardium: Lesion Volume and Effects on Coronary Arteries Early After Energy Application. Implications for Efficacy and Safety in Pediatric Patients"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","731"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Heart Rhythm"],["dc.bibliographiccitation.lastpage","739"],["dc.bibliographiccitation.volume","7"],["dc.contributor.author","Schneider, Heike E."],["dc.contributor.author","Kriebel, Thomas"],["dc.contributor.author","Jung, Klaus"],["dc.contributor.author","Gravenhorst, Verena D."],["dc.contributor.author","Paul, Thomas"],["dc.date.accessioned","2018-11-07T08:42:45Z"],["dc.date.available","2018-11-07T08:42:45Z"],["dc.date.issued","2010"],["dc.description.abstract","BACKGROUND Idiopathic ventricular tachycardia (VT) in children with a structurally normal heart can cause significant morbidity, and although rare, mortality. Conventional activation and pace mapping may be limited by nonsustained tachycardia or unstable hemodynamics. OBJECTIVE The aim of this study was to assess feasibility of catheter ablation of idiopathic VT in the pediatric population guided by noncontact mapping. METHODS Twenty consecutive pediatric patients with idiopathic VT underwent electrophysiologic study with the intention to use the noncontact mapping system EnSite 3000 (EnSite Array, St. Jude Medical Inc., Minneapolis, Minnesota). The multielectrode balloon array was introduced into the left or right ventricle, respectively, and tachycardia was analyzed using color-coded isopotential maps as well as reconstructed unipolar electrograms on the virtual geometry. The region of origin was identified in all of them, and the site of earliest activation with a QS pattern of the unipolar electrograms was guided for sites of ablation. RESULTS Idiopathic VT originated from the right ventricular outflow tract in 6 patients, from the left ventricle in 8, and from the aortic sinus cusp in 6 in this cohort with a median age of 14.4 (range: 4.8 to 20.9) years. Ablation was attempted in 18 of 20 children, and was acutely successful in 17 of these 18 (94%). During a mean follow-up of 2.3 +/- 1.7 years, VT recurred in 3, 2 of them have been treated with a second procedure, resulting in an overall intermediate-term success in 16 of 18 (89%) children with idiopathic VT. CONCLUSION Noncontact mapping can safely and effectively be used to map and guide catheter ablation of the tachycardia substrate of idiopathic VT in pediatric patients."],["dc.identifier.doi","10.1016/j.hrthm.2010.02.031"],["dc.identifier.isi","000278608300002"],["dc.identifier.pmid","20193776"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6219"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/19771"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.relation.issn","1547-5271"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Catheter ablation of idiopathic left and right ventricular tachycardias in the pediatric population using noncontact mapping"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1197"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","Pacing and Clinical Electrophysiology"],["dc.bibliographiccitation.lastpage","1202"],["dc.bibliographiccitation.volume","32"],["dc.contributor.author","Kriebel, Thomas"],["dc.contributor.author","Hermann, Hans-Peter"],["dc.contributor.author","Schneider, Heike"],["dc.contributor.author","Kroll, Maja"],["dc.contributor.author","Selle, Jakob"],["dc.contributor.author","Overwaul, Anna"],["dc.contributor.author","Sigler, Matthias"],["dc.contributor.author","Paul, Thomas"],["dc.date.accessioned","2021-11-22T14:31:49Z"],["dc.date.available","2021-11-22T14:31:49Z"],["dc.date.issued","2009"],["dc.description.abstract","BACKGROUND: Animal studies and clinical observations have demonstrated that radiofrequency current application at growing myocardium may result in coronary artery obstruction. Recently, cryoenergy has emerged as an effective alternative to radiofrequency ablation of arrhythmogenic substrates in pediatric patients. Up to now, there has been a lack of experimental data concerning the effects of cryoenergy application at growing myocardium. METHODS: During general anesthesia, selective coronary angiography of the right and left coronary artery was performed in 10 piglets (age: 6 weeks, body weight: 14-18 kg). Subsequently, cryoenergy was delivered at -75 degrees C for 4 minutes using a 7-F catheter with a 6-mm-tip electrode at the atrial aspect of the tricuspid valve annulus in a posterior and lateral position. Additional cryoenergy lesions were induced via a retrograde approach at the lateral and posterior atrial and ventricular aspect of the mitral valve annulus, respectively. Five animals were restudied after 48 hours by coronary angiography and intracoronary ultrasound and in the remaining five piglets after 3 and 6 months, respectively. RESULTS: Selective coronary angiography and intracoronary ultrasound studies did not demonstrate any evidence for coronary artery obstruction after 48 hours, 3 months, or 6 months after cryoenergy application. In addition, histological examinations of the cryolesions after 48 hours and after 6 months did not demonstrate any intimal proliferations of the coronary arteries, respectively. CONCLUSIONS: By means of the present study, we did not observe any affection of the coronary arteries after cryoenergy application at growing myocardium in young piglets."],["dc.description.abstract","Methods: During general anesthesia, selective coronary angiography of the right and left coronary artery was performed in 10 piglets (age: 6 weeks, body weight: 14-18 kg). Subsequently, cryoenergy was delivered at -75 degrees C for 4 minutes using a 7-F catheter with a 6-mm-tip electrode at the atrial aspect of the tricuspid valve annulus in a posterior and lateral position. Additional cryoenergy lesions were induced via a retrograde approach at the lateral and posterior atrial and ventricular aspect of the mitral valve annulus, respectively. Five animals were restudied after 48 hours by coronary angiography and intracoronary ultrasound and in the remaining five piglets after 3 and 6 months, respectively. Results: Selective coronary angiography and intracoronary ultrasound studies did not demonstrate any evidence for coronary artery obstruction after 48 hours, 3 months, or 6 months after cryoenergy application. In addition, histological examinations of the cryolesions after 48 hours and after 6 months did not demonstrate any intimal proliferations of the coronary arteries, respectively. Conclusions: By means of the present study, we did not observe any affection of the coronary arteries after cryoenergy application at growing myocardium in young piglets. (PACE 2009; 32:1197-1202)."],["dc.identifier.doi","10.1111/j.1540-8159.2009.02465.x"],["dc.identifier.isi","000269390500015"],["dc.identifier.pmid","19719499"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6288"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/93405"],["dc.language.iso","en"],["dc.notes.intern","Migrated from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell Publishing, Inc"],["dc.relation.issn","1540-8159"],["dc.rights.access","closedAccess"],["dc.subject.ddc","610"],["dc.subject.mesh","Animals"],["dc.subject.mesh","Coronary Artery Disease"],["dc.subject.mesh","Coronary Stenosis"],["dc.subject.mesh","Coronary Vessels"],["dc.subject.mesh","Cryosurgery"],["dc.subject.mesh","Risk Assessment"],["dc.subject.mesh","Swine"],["dc.title","Cryoablation at growing myocardium: no evidence of coronary artery obstruction or intimal plaque formation early and late after energy application."],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2162"],["dc.bibliographiccitation.issue","22"],["dc.bibliographiccitation.journal","Journal of the American College of Cardiology"],["dc.bibliographiccitation.lastpage","2168"],["dc.bibliographiccitation.volume","50"],["dc.contributor.author","Kriebel, Thomas"],["dc.contributor.author","Saul, J. Philip"],["dc.contributor.author","Schneider, Heike"],["dc.contributor.author","Sigler, Matthias"],["dc.contributor.author","Paul, Thomas"],["dc.date.accessioned","2018-11-07T10:51:31Z"],["dc.date.available","2018-11-07T10:51:31Z"],["dc.date.issued","2007"],["dc.description.abstract","Objectives The goal of this work was to assess efficacy of radiofrequency (RF) ablation of fast ventricular tachycardia (VT) in patients after surgical repair of tetralogy of Fallot (TOF) guided by noncontact mapping. Background Ventricular tachycardias after repair of TOF are associated with significant morbidity and mortality. Methods Ten patients after surgical repair of TOF underwent electrophysiological study for hemodynamically unstable VT using the noncontact mapping system. Dynamic substrate mapping was performed and activation was recorded during basic rhythm and induced VT (mean cycle length 269 ms) using color-coded isopotential maps and reconstructed unipolar electrograms. Results A total of 13 VTs were induced in the 10 patients. In 11 of 13 VTs, a macro-re-entrant mechanism was identified; 2 had a focal origin. For macro-re-entrant VT, RF current lesion lines were created between areas of residual conduction; in 2 patients, no RF current was delivered due to high risk of atrioventricular block. Focal applications were performed for the focal VTs. Ventricular tachycardia was not inducible after RF application in the 8 patients in whom ablation was attempted (100%, 80% of all patients). An internal cardioverter-defibrillator had already been implanted in 2 patients and was recommended to the rest of the group. During follow-up (mean 35.4 months), 6 of 8 patients with a successful procedure were still free of VT, and 2 patients had recurrence of VT with a different cycle length. Conclusions In patients with fast and unstable VT after surgical repair of TOF, noncontact mapping helped to identify the tachycardia substrate and allowed for effective and safe treatment by RF ablation."],["dc.identifier.doi","10.1016/j.jacc.2007.07.074"],["dc.identifier.isi","000251281900011"],["dc.identifier.pmid","18036455"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/48912"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.relation.issn","0735-1097"],["dc.title","Noncontact mapping and radiofrequency catheter ablation of fast and hemodynamically unstable ventricular tachycardia after surgical repair of tetralogy of Fallot"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","990"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Clinical Research in Cardiology"],["dc.bibliographiccitation.lastpage","997"],["dc.bibliographiccitation.volume","104"],["dc.contributor.author","Krause, Ulrich J."],["dc.contributor.author","Backhoff, David"],["dc.contributor.author","Klehs, Sophia"],["dc.contributor.author","Kriebel, Thomas"],["dc.contributor.author","Paul, Thomas"],["dc.contributor.author","Schneider, Heike E."],["dc.date.accessioned","2018-11-07T09:49:40Z"],["dc.date.available","2018-11-07T09:49:40Z"],["dc.date.issued","2015"],["dc.description.abstract","AV nodal reentrant tachycardia (AVNRT) is commonly encountered in pediatric patients. Definite treatment can be achieved by catheter ablation. The purpose of the study was to evaluate the efficacy and safety of AVNRT ablation focusing on children with a body weight a parts per thousand currency sign25 kg. Catheter ablation of AVNRT was attempted in 253 patients. Median age was 12.5 years; median body weight was 48.7 kg. 25 (9.9 %) children had a body weight a parts per thousand currency sign25 kg. Congenital heart disease was present in 6 patients (2.4 %). Procedural success was achieved in 98 % using radiofrequency, in 100 % using cryoenergy alone, and in 94 % using both energy sources. In patients with a body weight a parts per thousand currency sign25 kg, success was achieved in 96 %. In patients a parts per thousand currency sign25 kg, fluoroscopy and procedure duration did not differ from those > 25 kg. The rate of major complications was significantly higher in the patients a parts per thousand currency sign25 kg (12 vs. 2.2 %, p = 0.04). Permanent AV block after RF ablation occurred in 2 patients with congenital heart disease and one infant with a body weight of 8.7 kg. Catheter ablation of AVNRT in children and adolescents was safe and effective. Infants and small children with a body weight a parts per thousand currency sign25 kg had a higher prevalence of serious complications. This should alert physicians in decision making toward catheter ablation in these patients. In patients with congenital heart disease and different anatomy of the cardiac conduction system, operators must be aware of an increased risk for AV block."],["dc.identifier.doi","10.1007/s00392-015-0868-6"],["dc.identifier.isi","000363866600010"],["dc.identifier.pmid","25982591"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/35551"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","Heidelberg"],["dc.relation.issn","1861-0692"],["dc.relation.issn","1861-0684"],["dc.title","Catheter ablation of pediatric AV nodal reentrant tachycardia: results in small children"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","892"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Pediatric Cardiology"],["dc.bibliographiccitation.lastpage","898"],["dc.bibliographiccitation.volume","37"],["dc.contributor.author","Backhoff, David"],["dc.contributor.author","Klehs, Sophia"],["dc.contributor.author","Mueller, Matthias J."],["dc.contributor.author","Schneider, Heike"],["dc.contributor.author","Kriebel, Thomas"],["dc.contributor.author","Paul, Thomas"],["dc.contributor.author","Krause, Ulrich J."],["dc.date.accessioned","2018-11-07T10:13:27Z"],["dc.date.available","2018-11-07T10:13:27Z"],["dc.date.issued","2016"],["dc.description.abstract","Accessory atrioventricular pathways (AP) are the most common substrate for paroxysmal supraventricular tachycardia in infants and small children. Up-to-date data on AP ablation in infants and small children are limited. The aim of the present study was to gain additional insight into radiofrequency (RF) catheter ablation of AP in infants and toddlers focusing on efficacy and safety in patients with a body weight of a parts per thousand currency sign 15 kg. Since 10/2002, RF ablation of AP was performed in 281 children in our institution. Indications, procedural data as well as success and complication rates in children with a body weight a parts per thousand currency sign 15 kg (n = 22) were compared with children > 15 kg (n = 259). Prevalence of structural heart anomalies was significantly higher among children a parts per thousand currency sign 15 kg (27 vs. 5.7 %; p = 0.001). Procedure duration (median 262 vs. 177 min; p = 0.001) and fluoroscopy time (median 20.6 vs. 14.0 min; p = 0.007) were significantly longer among patients a parts per thousand currency sign 15 kg. Procedural success rate did not differ significantly between the two groups (82 vs. 90 %). More RF lesions were required for AP ablation in the smaller patients (median 12 vs. 7; p = 0.019). Major complication rate was significantly higher in children a parts per thousand currency sign 15 kg (9 vs. 1.1 %; p = 0.05) with femoral vessel occlusion being the only major adverse event in patients a parts per thousand currency sign 15 kg. Catheter ablation of AP in children was effective irrespective of body weight. In children a parts per thousand currency sign 15 kg, however, procedures were more challenging and time-consuming. Complication rate and number of RF lesions in smaller children were higher when compared to older children."],["dc.identifier.doi","10.1007/s00246-016-1365-z"],["dc.identifier.isi","000377722400012"],["dc.identifier.pmid","26961570"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/40437"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","1432-1971"],["dc.relation.issn","0172-0643"],["dc.title","Radiofrequency Catheter Ablation of Accessory Atrioventricular Pathways in Infants and Toddlers a parts per thousand currency sign 15 kg"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","461"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Heart Rhythm"],["dc.bibliographiccitation.lastpage","467"],["dc.bibliographiccitation.volume","6"],["dc.contributor.author","Schneider, Heike E."],["dc.contributor.author","Kriebel, Thomas"],["dc.contributor.author","Gravenhorst, Verena D."],["dc.contributor.author","Paul, Thomas"],["dc.date.accessioned","2018-11-07T08:31:06Z"],["dc.date.available","2018-11-07T08:31:06Z"],["dc.date.issued","2009"],["dc.description.abstract","BACKGROUND Several case reports have documented coronary artery stenosis or even occlusion after radiofrequency energy ablation (RFA) in children and adults. Coronary involvement early and (ate after RFA has also been described in animal models. OBJECTIVE The purpose of this study was to assess prospectively the incidence of coronary artery injury early after catheter ablation for supraventricular tachycardias (SVT) in children. METHODS From October 2002 to January 2008, 212 consecutive patients younger than 21. years with SVT underwent selective coronary angiography before and 30 minutes after RFA or cryoablation. RESULTS Median patient age was 12 years (range 0.3-20.4 years), and median body weight was 47 kg (range 5.5-130 kg). An accessory pathway was diagnosed in 112 patients, AV nodal reentrant tachycardia (AVNRT) in 84 patients, and both an accessory pathway and AVNRT in 16 patients. Congenital heart disease was present in 31 patients. In 2 of 117 patients who had RFA for an accessory pathway, an acute reduction in luminal diameter of the coronary artery adjacent to the ablation site was observed. These two patients with a structurally normal heart showed ST-segment changes with normalization of the ECG within 1 week. Both were clinically asymptomatic, and two-dimensional echocardiography documented normal ventricular function. Noninvasive testing did not reveal any evidence of persistent myocardial ischemia. No coronary artery damage was noted after ablation for AVNRT or after ablation with cryoenergy. CONCLUSION Coronary artery narrowing adjacent to the RFA site was noted in 2 of 117 patients with an accessory pathway and occurred only in patients with a posteroseptal pathway. Coronary angiography could be helpful in avoiding coronary lesions in these settings."],["dc.identifier.doi","10.1016/j.hrthm.2009.01.029"],["dc.identifier.isi","000264919500004"],["dc.identifier.pmid","19324303"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6217"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/17044"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.relation.issn","1547-5271"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Incidence of coronary artery injury immediately after catheter ablation for supraventricular tachycardias in infants and children"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1319"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","Pacing and Clinical Electrophysiology"],["dc.bibliographiccitation.lastpage","1325"],["dc.bibliographiccitation.volume","29"],["dc.contributor.author","Kriebel, Thomas"],["dc.contributor.author","Ruschewski, Wolfgang"],["dc.contributor.author","Gonzalez Y Gonzalez, Maria"],["dc.contributor.author","Walter, Katharina"],["dc.contributor.author","Kroll, Johannes"],["dc.contributor.author","Kampmann, Christoph"],["dc.contributor.author","Heinemann, Markus"],["dc.contributor.author","Schneider, Heike"],["dc.contributor.author","Paul, Thomas"],["dc.date.accessioned","2018-11-07T08:55:26Z"],["dc.date.available","2018-11-07T08:55:26Z"],["dc.date.issued","2006"],["dc.description.abstract","Background: There is no clear methodology for implantation of an internal cardioverter-defibrillator (ICD) in infants and small children. The aim of this study was to assess efficacy and safety of an extracardiac ICD implantation technique in pediatric patients. Patients and Methods: An extracardiac ICD system was implanted in eight patients (age: 0.3-8 years; body weight: 4-29 kg). Under fluoroscopic guidance a defibrillator lead was tunneled subcutaneously starting from the anterior axillar line along the course of the 6th rib until almost reaching the vertebral column. After a partial inferior sternotomy, bipolar steroid-eluting sensing and pacing leads were sutured to the atrial wall (n = 2) and to the anterior wall of the right ventricle (n = 8). The ICD device was implanted as \"active can\" in the upper abdomen. Sensing, pacing, and defibrillation thresholds (DFTs) as well as impedances were verified intraoperatively and 3 months later, respectively. Results: In seven of eight patients, intraoperative DFT between subcutaneous lead and device was <15 J. In the eighth patient ICD implantation was technically not feasible due to a DFT >20 J. During follow-up (mean 14.5 months) appropriate and effective ICD discharges were noted in two patients. DFT remained stable after 3 months in four of six patients retested. A revision was required in one patient due to lead migration and in another patient due to a lead break. Conclusions: In infants and small children, extracardiac ICD implantation was technically feasible. Experience and follow-up are still limited. The course of the DFT is unknown, facing further growth of the patients."],["dc.identifier.doi","10.1111/j.1540-8159.2006.00542.x"],["dc.identifier.isi","000243530800001"],["dc.identifier.pmid","17201837"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/22902"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Blackwell Publishing"],["dc.relation.issn","0147-8389"],["dc.title","ICD implantation in infants and small children: The extracardiac technique"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]