Wolf, Katrin

[["dc.bibliographiccitation.firstpage","232"],["dc.bibliographiccitation.issue","3-4"],["dc.bibliographiccitation.journal","Cytogenetic and Genome Research"],["dc.bibliographiccitation.lastpage","244"],["dc.bibliographiccitation.volume","121"],["dc.contributor.author","Rzymski, T."],["dc.contributor.author","Grzmil, Pawel"],["dc.contributor.author","Meinhardt, Andreas"],["dc.contributor.author","Wolf, S."],["dc.contributor.author","Burfeind, Peter"],["dc.date.accessioned","2018-11-07T11:19:47Z"],["dc.date.available","2018-11-07T11:19:47Z"],["dc.date.issued","2008"],["dc.description.abstract","PHF5A is a highly conserved protein from yeast to man, and based on studies in yeast, it was suggested that the homologous protein RDS3P in S. cerevisiae takes part in the organization of U2 snRNP particles. By using the yeast two-hybrid assay we could demonstrate that PHF5A interacted both with ATP-dependent helicases EP400 and DDX1 and with arginine-serine (RS)-rich domains of splicing factors U2AF1 and SFRS5 in mouse. Furthermore, domain interaction studies revealed that PHF5A interaction with EP400 and DDX1 is restricted to the N-terminal part of PHF5A, whereas the C-terminal region of PHF5A was found to be responsible for the association with U2AF1 and SFRS5. By using the yeast three-hybrid assay, we could further show that both EP400 and DDX1 interacted only indirectly with U2AF1 and SFRS5 proteins via the bridge protein PHF5A. The subcellular localization of a PHF5A-GFP fusion protein was predominantly observed in the nucleus and, in addition, PHF5A co-localized with both U2AF1 and SFRS5 proteins in nuclear speckles of NIH3T3 cells. Moreover, expression analyses demonstrated that PHF5A and U2AF1 gene expression coincided in spermatocytes during murine spermatogenesis and interaction between these proteins was also detectable in the spermatocyte-specific cell line GC-4spc by using in vivo co-immunoprecipitation studies. Taken together, our results indicate that PHF5A resembles a protein which interacts with splicing factors U2AF1 and SFRS5 and helicases EP400 and DDX1 and functions as a bridge protein between these proteins. Copyright (c) 2008 S. Karger AG, Basel."],["dc.description.sponsorship","Deutsche Forschungsgemeinschaft [SFB 271]"],["dc.identifier.doi","10.1159/000138890"],["dc.identifier.isi","000259032000010"],["dc.identifier.pmid","18758164"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/9352"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/55369"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Karger"],["dc.relation.issn","1424-8581"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","PHF5A represents a bridge protein between splicing proteins and ATP-dependent helicases and is differentially expressed during mouse spermatogenesis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","A62"],["dc.bibliographiccitation.journal","Astronomy and Astrophysics"],["dc.bibliographiccitation.volume","552"],["dc.contributor.author","Mosoni, L."],["dc.contributor.author","Sipos, N."],["dc.contributor.author","Abraham, P."],["dc.contributor.author","Moor, A."],["dc.contributor.author","Kospal, A."],["dc.contributor.author","Henning, T. H."],["dc.contributor.author","Juhasz, A."],["dc.contributor.author","Kun, M."],["dc.contributor.author","Leinert, Ch."],["dc.contributor.author","Quanz, S. P."],["dc.contributor.author","Ratzka, Th."],["dc.contributor.author","Schegerer, Alexander A."],["dc.contributor.author","van Boekel, R."],["dc.contributor.author","Wolf, S."],["dc.date.accessioned","2018-11-07T09:26:22Z"],["dc.date.available","2018-11-07T09:26:22Z"],["dc.date.issued","2013"],["dc.description.abstract","Context. It is hypothesized that low-mass young stellar objects undergo eruptive phases during their early evolution. These eruptions are thought to be caused by highly increased mass accretion from the disk onto the star, and therefore play an important role in the early evolution of Sun-like stars, of their circumstellar disks (structure, dust composition), and in the formation of their planetary systems. The outburst of V1647 Ori between 2003 and 2006 offered a rare opportunity to investigate such an accretion event. Aims. By means of our interferometry observing campaign during this outburst, supplemented by other observations, we investigate the temporal evolution of the inner circumstellar structure of V1647 Ori, the region where Earth-like planets could be born. We also study the role of the changing extinction in the brightening of the object and separate it from the accretional brightening. Methods. We observed V1647 Ori with MIDI on the VLTI at two epochs in this outburst. First, during the slowly fading plateau phase (2005 March) and second, just before the rapid fading of the object (2005 September), which ended the outburst. We used the radiative transfer code MC3D to fit the interferometry data and the spectral energy distributions from five different epochs at different stages of the outburst. The comparison of these models allowed us to trace structural changes in the system on AU-scales. We also considered qualitative alternatives for the interpretation of our data. Results. We found that the disk and the envelope are similar to those of non-eruptive young stars and that the accretion rate varied during the outburst. We also found evidence for the increase of the inner radii of the circumstellar disk and envelope at the beginning of the outburst. Furthermore, the change of the interferometric visibilities indicates structural changes in the circumstellar material. We test a few scenarios to interpret these data. We also speculate that the changes are caused by the fading of the central source, which is not immediately followed by the fading of the outer regions. Conclusions. We found that most of our results fit in the canonical picture of young eruptive stars. Our study provided dynamical information from the regions of the innermost few AU of the system: changes of the inner radii of the disk and envelope. However, if the delay in the fading of the disk is responsible for the changes seen in the MIDI data, the effect should be confirmed by dynamical modeling."],["dc.identifier.doi","10.1051/0004-6361/201218770"],["dc.identifier.isi","000317912000062"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/10130"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/30283"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Edp Sciences S A"],["dc.relation","info:eu-repo/grantAgreement/EC/FP7/226604/EU//OPTICON"],["dc.relation.issn","0004-6361"],["dc.relation.orgunit","Fakultät für Physik"],["dc.title","Dynamics during outburst VLTI observations of the young eruptive star V1647 Orionis during its 2003-2006 outburst"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","A11"],["dc.bibliographiccitation.journal","Astronomy and Astrophysics"],["dc.bibliographiccitation.volume","555"],["dc.contributor.author","Eiroa, C."],["dc.contributor.author","Marshall, J. P."],["dc.contributor.author","Mora, A."],["dc.contributor.author","Montesinos, B."],["dc.contributor.author","Absil, O."],["dc.contributor.author","Augereau, J. Ch."],["dc.contributor.author","Bayo, A."],["dc.contributor.author","Bryden, G."],["dc.contributor.author","Danchi, W."],["dc.contributor.author","del Burgo, C."],["dc.contributor.author","Ertel, Suitbert"],["dc.contributor.author","Fridlund, M."],["dc.contributor.author","Heras, A. M."],["dc.contributor.author","Krivov, A. V."],["dc.contributor.author","Launhardt, R."],["dc.contributor.author","Liseau, R."],["dc.contributor.author","Loehne, T."],["dc.contributor.author","Maldonado, J."],["dc.contributor.author","Pilbratt, G. L."],["dc.contributor.author","Roberge, A."],["dc.contributor.author","Rodmann, Jens"],["dc.contributor.author","Sanz-Forcada, J."],["dc.contributor.author","Solano, E."],["dc.contributor.author","Stapelfeldt, K."],["dc.contributor.author","Thebault, P."],["dc.contributor.author","Wolf, S."],["dc.contributor.author","Ardila, D."],["dc.contributor.author","Arevalo, M."],["dc.contributor.author","Beichmann, C."],["dc.contributor.author","Faramaz, V."],["dc.contributor.author","Gonzalez-Garcia, B. M."],["dc.contributor.author","Gutierrez, R- A."],["dc.contributor.author","Lebreton, J."],["dc.contributor.author","Martinez-Arnaiz, R."],["dc.contributor.author","Meeus, G."],["dc.contributor.author","Montes, D."],["dc.contributor.author","Olofsson, G."],["dc.contributor.author","Su, K. Y. L."],["dc.contributor.author","White, G. J."],["dc.contributor.author","Barrado, D."],["dc.contributor.author","Fukagawa, M."],["dc.contributor.author","Gruen, E."],["dc.contributor.author","Kamp, I."],["dc.contributor.author","Lorente, R."],["dc.contributor.author","Morbidelli, A."],["dc.contributor.author","Mueller, S."],["dc.contributor.author","Mutschke, H."],["dc.contributor.author","Nakagawa, T."],["dc.contributor.author","Ribas, I."],["dc.contributor.author","Walker, H."],["dc.date.accessioned","2018-11-07T09:22:46Z"],["dc.date.available","2018-11-07T09:22:46Z"],["dc.date.issued","2013"],["dc.description.abstract","Context. Debris discs are a consequence of the planet formation process and constitute the fingerprints of planetesimal systems. Their solar system counterparts are the asteroid and Edgeworth-Kuiper belts. Aims. The DUNES survey aims at detecting extra-solar analogues to the Edgeworth-Kuiper belt around solar-type stars, putting in this way the solar system into context. The survey allows us to address some questions related to the prevalence and properties of planetesimal systems. Methods. We used Herschel/PACS to observe a sample of nearby FGK stars. Data at 100 and 160 mu m were obtained, complemented in some cases with observations at 70 mu m, and at 250, 350 and 500 mu m using SPIRE. The observing strategy was to integrate as deep as possible at 100 mu m to detect the stellar photosphere. Results. Debris discs have been detected at a fractional luminosity level down to several times that of the Edgeworth-Kuiper belt. The incidence rate of discs around the DUNES stars is increased from a rate of similar to 12.1% +/- 5% before Herschel to similar to 20.2% +/- 2%. A significant fraction (similar to 52%) of the discs are resolved, which represents an enormous step ahead from the previously known resolved discs. Some stars are associated with faint far-IR excesses attributed to a new class of cold discs. Although it cannot be excluded that these excesses are produced by coincidental alignment of background galaxies, statistical arguments suggest that at least some of them are true debris discs. Some discs display peculiar SEDs with spectral indexes in the 70-160 mu m range steeper than the Rayleigh-Jeans one. An analysis of the debris disc parameters suggests that a decrease might exist of the mean black body radius from the F-type to the K-type stars. In addition, a weak trend is suggested for a correlation of disc sizes and an anticorrelation of disc temperatures with the stellar age."],["dc.identifier.doi","10.1051/0004-6361/201321050"],["dc.identifier.fs","605000"],["dc.identifier.isi","000322008600011"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/10655"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/29427"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Edp Sciences S A"],["dc.relation.issn","1432-0746"],["dc.relation.orgunit","Fakultät für Physik"],["dc.title","DUst around NEarby Stars. The survey observational results"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","469"],["dc.bibliographiccitation.issue","1-3"],["dc.bibliographiccitation.journal","Biogeochemistry"],["dc.bibliographiccitation.lastpage","483"],["dc.bibliographiccitation.volume","111"],["dc.contributor.author","Wolf, Katrin"],["dc.contributor.author","Flessa, Heiner"],["dc.contributor.author","Veldkamp, Edzo"],["dc.date.accessioned","2017-09-07T11:43:38Z"],["dc.date.available","2017-09-07T11:43:38Z"],["dc.date.issued","2011"],["dc.identifier.doi","10.1007/s10533-011-9681-0"],["dc.identifier.gro","3150182"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/8839"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/6918"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.relation.issn","0168-2563"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Atmospheric methane uptake by tropical montane forest soils and the contribution of organic layers"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.peerReviewed","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","A61"],["dc.bibliographiccitation.journal","Astronomy and Astrophysics"],["dc.bibliographiccitation.volume","544"],["dc.contributor.author","Ertel, Suitbert"],["dc.contributor.author","Wolf, S."],["dc.contributor.author","Rodmann, Jens"],["dc.date.accessioned","2018-11-07T09:07:34Z"],["dc.date.available","2018-11-07T09:07:34Z"],["dc.date.issued","2012"],["dc.description.abstract","Context. Debris disks are commonly considered to be a by-product of planet formation. Structures in debris disks induced by planet-disk interaction are promising to provide valuable constraints on the existence and properties of embedded planets. Aims. We investigate the observability of structures in debris disks induced by planet-disk interaction with future facilities in a systematic way. High-sensitivity, high angular resolution observations with large (sub-) mm interferometers and large space-based telescopes operating in the near-to mid-infrared wavelength range are considered. Methods. The observability of debris disks with the Atacama LargeMillimeter/submillimeter Array (ALMA) is studied on the basis of a simple analytical disk model. Furthermore, N-body simulations are used to model the spatial dust distribution in debris disks under the influence of planet-disk interaction. From these simulations, images at optical scattered light to millimeter thermal re-emission are computed. Available information about the expected capabilities of ALMA and the James Webb Space Telescope (JWST) are used to investigate the observability of characteristic disk structures with these facilities through spatially resolved imaging. Results. Our simulations show that planet-disk interaction can result in prominent structures in the whole considered wavelength range. The exact result depends on the configuration of the planet-disk system and on the observing wavelength which provides the opportunity of detecting and characterizing extrasolar planets in a range of masses and radial distances from the star that is not accessible to other techniques. Facilities that will be available in the near future at both considered wavelength ranges are shown to provide the capabilities to spatially resolve and characterize structures in debris disks that arise because of planet-disk interaction. Limitations are revealed and suggestions for possible instrument setups and observing strategies are given. In particular, ALMA is limited by its sensitivity to surface brightness, which requires a trade-off between sensitivity and spatial resolution. Space-based mid-infrared observations will be able to detect and spatially resolve regions in debris disks even at a distance of several tens of AU from the star, where the emission from debris disks in this wavelength range is expected to be low. Conclusions. Both ALMA and the planned space-based near-to mid-infrared telescopes will provide unprecedented capabilities to study planet-disk interaction in debris disks. In particular, a combination of observations at both wavelengths will provide very strong constraints on the planetary/planetesimal systems."],["dc.identifier.doi","10.1051/0004-6361/201219236"],["dc.identifier.fs","596751"],["dc.identifier.isi","000308290100061"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/9611"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/25826"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Edp Sciences S A"],["dc.relation.issn","0004-6361"],["dc.relation.orgunit","Fakultät für Physik"],["dc.title","Observing planet-disk interaction in debris disks"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","186"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Cytogenetic and Genome Research"],["dc.bibliographiccitation.lastpage","200"],["dc.bibliographiccitation.volume","125"],["dc.contributor.author","Grzmil, Pawel"],["dc.contributor.author","Konietzko, J."],["dc.contributor.author","Boehm, D."],["dc.contributor.author","Hoelter, Sabine M."],["dc.contributor.author","Aguilar, A."],["dc.contributor.author","Javaheri, A."],["dc.contributor.author","Kalaydjiev, S."],["dc.contributor.author","Adler, Thure"],["dc.contributor.author","Bolle, I."],["dc.contributor.author","Adham, Ibrahim M."],["dc.contributor.author","Dixkens, C."],["dc.contributor.author","Wolf, S."],["dc.contributor.author","Fuchs, H."],["dc.contributor.author","Gailus-Durne, V."],["dc.contributor.author","Wurst, Wolfgang"],["dc.contributor.author","Ollert, Markus W."],["dc.contributor.author","Busch, D."],["dc.contributor.author","Schulz, H."],["dc.contributor.author","de Angelis, Martin Hrabe"],["dc.contributor.author","Burfeind, Peter"],["dc.date.accessioned","2018-11-07T08:34:19Z"],["dc.date.available","2018-11-07T08:34:19Z"],["dc.date.issued","2009"],["dc.description.abstract","The non-imprinted in Prader-Willi/Angelman syndrome (NIPA) proteins are highly conserved receptors or transporters. Translocation of NIPA genes were found in patients with Prader-Willi syndrome, and loss-of-function of the NIPA1 gene was identified in hereditary spastic paraplegia. The family of NIPA-like domain containing (NPAL) proteins is closely related to the NIPA proteins, but to date nothing is known about their function. Here, we could demonstrate that both human NPAL3 and mouse Npal3 are ubiquitously expressed and encode highly conserved proteins. To further elucidate the function of the Npal3 gene, knockout (Npal3(-/-)) mice were generated. Intensive phenotypic analyses revealed that disruption of the Npal3 gene results in a pleiotropic phenotype. The function of the nervous system was impaired in both mutant males and females which could be demonstrated in behavioral tests. In addition, in Npal3 mutants the number of NK cells was decreased and changes in IgM, IgG(2), and IgA were observed, indicating that the immune system is also affected. Interestingly, increased IgE levels as well as impaired lung functions were observed in mutant males but not in mutant females. It should be noted that the human NPAL3 gene is located at 1p36.12 -> p35.1, and atopic diseases were previously linked to this genomic region. Thus, the Npal3(-/-) mice could serve as a valuable model system for studying atopic diseases. Copyright (C) 2009 S. Karger AG, Basel"],["dc.identifier.doi","10.1159/000230003"],["dc.identifier.isi","000269572100003"],["dc.identifier.pmid","19738379"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/9315"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/17783"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Karger"],["dc.relation.issn","1424-8581"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Targeted Disruption of the Mouse Npal3 Gene Leads to Deficits in Behavior, Increased IgE Levels, and Impaired Lung Function"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]