Müller, Nadine Erika

[["dc.bibliographiccitation.firstpage","120"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Aggressive Behavior"],["dc.bibliographiccitation.lastpage","128"],["dc.bibliographiccitation.volume","45"],["dc.contributor.author","Paschek, Nicole"],["dc.contributor.author","Müller, Nadine"],["dc.contributor.author","Heistermann, Michael"],["dc.contributor.author","Ostner, Julia"],["dc.contributor.author","Schülke, Oliver"],["dc.date.accessioned","2022-10-06T13:32:22Z"],["dc.date.available","2022-10-06T13:32:22Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1002/ab.21801"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/115354"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.issn","0096-140X"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","Subtypes of aggression and their relation to anxiety in Barbary macaques"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","120"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Aggressive Behavior"],["dc.bibliographiccitation.lastpage","128"],["dc.bibliographiccitation.volume","45"],["dc.contributor.author","Paschek, Nicole"],["dc.contributor.author","Müller, Nadine"],["dc.contributor.author","Heistermann, Michael"],["dc.contributor.author","Ostner, Julia"],["dc.contributor.author","Schülke, Oliver"],["dc.date.accessioned","2020-12-10T14:06:31Z"],["dc.date.available","2020-12-10T14:06:31Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1002/ab.v45.2"],["dc.identifier.issn","0096-140X"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/69928"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Subtypes of aggression and their relation to anxiety in Barbary macaques"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","41973"],["dc.bibliographiccitation.journal","Scientific Reports"],["dc.bibliographiccitation.volume","7"],["dc.contributor.author","Müller, Nadine"],["dc.contributor.author","Heistermann, Michael"],["dc.contributor.author","Strube, Christina"],["dc.contributor.author","Schülke, Oliver"],["dc.contributor.author","Ostner, Julia"],["dc.date.accessioned","2017-09-07T11:54:37Z"],["dc.date.available","2017-09-07T11:54:37Z"],["dc.date.issued","2017"],["dc.description.abstract","Studying host parasite interactions and their implications for evolution and ecology recently received increasing attention, particularly with regard to host physiology and immunity. Here we assess variation of urinary neopterin (uNEO), a marker of cellular immune activation and iummunosenescence, in response to age and anthelmintic treatment in semi-free ranging Barbary macaques (Macaca sylvanus). Urinary NEO levels were measured via enzyme-immunoassay from 179 urine samples of 43 individuals between 5–29 years of age. Efficiency of treatment was assessed by Mc Master flotation on repeated faecal samples, including 18 untreated individuals as control group. We used linear mixed models with age and parasite status as main effects, controlling for sex and physical condition, assessed through urinary C-Peptide-levels, with social group and ID as random factors. Urinary NEO levels significantly increased with age, suggesting that changes in aging Barbary macaque immune responses are consistent with immunosenescence described in human and nonhuman primates and can be detected via uNEO measurements. Anthelmintic treatment, however, had no influence on uNEO levels, potentially due to quick reinfections or attenuated immune responses in repeated infections. We conclude that uNEO is a potential non-invasive marker for immune function and particularly immunosenescence in wildlife."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2017"],["dc.identifier.doi","10.1038/srep41973"],["dc.identifier.gro","3151449"],["dc.identifier.pmid","28155915"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14334"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/8251"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","final"],["dc.notes.submitter","chake"],["dc.relation.issn","2045-2322"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Age, but not anthelmintic treatment, is associated with urinary neopterin levels in semi-free ranging Barbary macaques"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.peerReviewed","no"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","230"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","American Journal of Primatology"],["dc.bibliographiccitation.lastpage","238"],["dc.bibliographiccitation.volume","76"],["dc.contributor.author","Müller, Nadine"],["dc.contributor.author","Ostner, Julia"],["dc.contributor.author","Schülke, Oliver"],["dc.contributor.author","Walter, Lutz"],["dc.date.accessioned","2017-09-07T11:54:39Z"],["dc.date.available","2017-09-07T11:54:39Z"],["dc.date.issued","2013"],["dc.description.abstract","The major histocompatibility complex (MHC) plays an important role in the immune response and may thus crucially affect an individual's fitness, relevant also for studies on evolutionary ecology and wildlife conservation. Detailed knowledge on the genomic organization, polymorphism and diversity of the MHC has a narrow taxonomic focus though and among macaques is only available for rhesus and long-tailed macaques—the species most commonly kept for biomedical research. The lack of data on wild populations is largely due to the difficulty of obtaining blood or tissue samples necessary for genotyping approaches. Here, we aimed at analyzing MHC-DRB from non-invasively collected fecal samples in wild Assamese macaques (Macaca assamensis), utilizing the MHC-DRB-STR (D6S2878) microsatellite marker. Due to the fecal DNA source incomplete genotypes occurred, which may be improved in the future by method refinement. We detected 28 distinct DRB-STR lengths in 43 individuals with individual genotypes containing 1–9 MHC-DRB-STRs and defined four haplotypes segregating between families in Mendelian fashion. Our results indicate that variability and diversity of MHC-DRB in Assamese macaques is comparable to that of other macaque species and importantly, that fecal samples can be used for non-invasive analysis of MHC genes after refinement of the applied methods, opening a number of opportunities for MHC research on natural populations."],["dc.identifier.doi","10.1002/ajp.22225"],["dc.identifier.gro","3151473"],["dc.identifier.pmid","24151109"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/8278"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.notes.submitter","chake"],["dc.relation.issn","0275-2565"],["dc.title","Towards the non-invasive assessment of MHC genotype in wild primates: Analysis of wild assamese macaqueMHC-DRBfrom fecal samples"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.peerReviewed","no"],["dspace.entity.type","Publication"]]