Now showing 1 - 5 of 5
  • 2019Journal Article
    [["dc.bibliographiccitation.journal","European Journal of Soil Science"],["dc.contributor.author","Xiao, M."],["dc.contributor.author","Zang, H."],["dc.contributor.author","Ge, T."],["dc.contributor.author","Chen, A."],["dc.contributor.author","Zhu, Z."],["dc.contributor.author","Zhou, P."],["dc.contributor.author","Atere, C. T."],["dc.contributor.author","Wu, J."],["dc.contributor.author","Su, Y."],["dc.contributor.author","Kuzyakov, Y."],["dc.date.accessioned","2020-12-10T18:28:32Z"],["dc.date.available","2020-12-10T18:28:32Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1111/ejss.12811"],["dc.identifier.eissn","1365-2389"],["dc.identifier.issn","1351-0754"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/76357"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Effect of nitrogen fertilizer on rice photosynthate allocation and Carbon input in paddy soil"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2014Journal Article Research Paper
    [["dc.bibliographiccitation.artnumber","5263"],["dc.bibliographiccitation.firstpage","1"],["dc.bibliographiccitation.journal","Nature Communications"],["dc.bibliographiccitation.lastpage","6"],["dc.bibliographiccitation.volume","5"],["dc.contributor.author","Ge, Yan"],["dc.contributor.author","Draycheva, Albena"],["dc.contributor.author","Bornemann, Thomas"],["dc.contributor.author","Rodnina, Marina V."],["dc.contributor.author","Wintermeyer, Wolfgang"],["dc.date.accessioned","2017-09-07T11:45:28Z"],["dc.date.available","2017-09-07T11:45:28Z"],["dc.date.issued","2014"],["dc.description.abstract","Proteins are co-translationally inserted into the bacterial plasma membrane via the SecYEG translocon by lateral release of hydrophobic transmembrane segments into the phospholipid bilayer. The trigger for lateral opening of the translocon is not known. Here we monitor lateral opening by photo-induced electron transfer (PET) between two fluorophores attached to the two SecY helices at the rim of the gate. In the resting translocon, the fluorescence is quenched, consistent with a closed conformation. Ribosome binding to the translocon diminishes PET quenching, indicating opening of the gate. The effect is larger with ribosomes exposing hydrophobic transmembrane segments and vanishes at low temperature. We propose a temperature-dependent dynamic equilibrium between closed and open conformations of the translocon that is shifted towards partially and fully open by ribosome binding and insertion of a hydrophobic peptide, respectively. The combined effects of ribosome and peptide binding allow for co-translational membrane insertion of successive transmembrane segments."],["dc.identifier.doi","10.1038/ncomms6263"],["dc.identifier.gro","3142041"],["dc.identifier.isi","000343985700002"],["dc.identifier.pmid","25314960"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/3889"],["dc.language.iso","en"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.relation.issn","2041-1723"],["dc.title","Lateral opening of the bacterial translocon on ribosome binding and signal peptide insertion"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dspace.entity.type","Publication"]]
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  • 2022Journal Article
    [["dc.bibliographiccitation.firstpage","369"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Biophysical Reviews"],["dc.bibliographiccitation.lastpage","379"],["dc.bibliographiccitation.volume","14"],["dc.contributor.author","Li, Amy"],["dc.contributor.author","Campbell, K."],["dc.contributor.author","Lal, S."],["dc.contributor.author","Ge, Y."],["dc.contributor.author","Keogh, A."],["dc.contributor.author","Macdonald, P. S."],["dc.contributor.author","Lau, P."],["dc.contributor.author","Lai, John"],["dc.contributor.author","Linke, W. A."],["dc.contributor.author","Van der Velden, J."],["dc.contributor.author","dos Remedios, Cristobal"],["dc.date.accessioned","2022-04-01T10:01:32Z"],["dc.date.available","2022-04-01T10:01:32Z"],["dc.date.issued","2022"],["dc.description.abstract","Abstract In this review, we present our current understanding of peripartum cardiomyopathy (PPCM) based on reports of the incidence, diagnosis and current treatment options. We summarise opinions on whether PPCM is triggered by vascular and/or hormonal causes and examine the influence of comorbidities such as preeclampsia. Two articles published in 2021 strongly support the hypothesis that PPCM may be a familial disease. Using large cohorts of PPCM patients, they summarised the available genomic DNA sequence data that are expressed in human cardiomyocytes. While PPCM is considered a disease predominately affecting the left ventricle, there are data to suggest that some cases also involve right ventricular failure. Finally, we conclude that there is sufficient evidence to warrant an RNAseq investigation and that this would be most informative if performed at the cardiomyocytes level rather than analysing genomic DNA from the peripheral circulation. Given the rarity of PPCM, the combined resources of international human heart tissue biobanks have assembled 30 ventricular tissue samples from PPCM patients, and we are actively seeking to enlarge this patient base by collaborating with human heart tissue banks and research laboratories who would like to join this endeavour."],["dc.description.sponsorship","La Trobe University"],["dc.identifier.doi","10.1007/s12551-022-00930-0"],["dc.identifier.pii","930"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/105686"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-530"],["dc.relation.eissn","1867-2469"],["dc.relation.issn","1867-2450"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Peripartum cardiomyopathy: a global effort to find the cause and cure for the rare and little understood disease"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2016Journal Article
    [["dc.bibliographiccitation.firstpage","1223"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","American Journal of Neuroradiology"],["dc.bibliographiccitation.lastpage","1230"],["dc.bibliographiccitation.volume","37"],["dc.contributor.author","Wuerfel, J."],["dc.contributor.author","Brisset, J.- C."],["dc.contributor.author","Liu, S."],["dc.contributor.author","Haacke, E. M."],["dc.contributor.author","Ge, Y."],["dc.contributor.author","Chawla, Sanjeev"],["dc.contributor.author","Kister, Ilya"],["dc.contributor.author","Sinnecker, Tim"],["dc.contributor.author","Dusek, Petr"],["dc.contributor.author","Paul, Friedemann"],["dc.date.accessioned","2020-12-10T18:44:05Z"],["dc.date.available","2020-12-10T18:44:05Z"],["dc.date.issued","2016"],["dc.description.abstract","Twenty-one patients with MS and 21 patients with neuromyelitis optica underwent 7T high-resolution 2D-gradient-echo-T2 and 3D-susceptibility-weighted imaging. An in-house-developed algorithm was used to reconstruct quantitative susceptibility mapping from SWI. Of the patients with MS, 19 (90.5%) demonstrated at least 1 quantitative susceptibility mapping-hyperintense lesion, and 11/21 (52.4%) had iron-laden lesions. No quantitative susceptibility mapping-hyperintense or iron-laden lesions were observed in any patients with neuromyelitis optica. The authors conclude that ultra-high-field MR imaging may be useful in distinguishing MS from neuromyelitis optica. BACKGROUND AND PURPOSE: Characterization of iron deposition associated with demyelinating lesions of multiple sclerosis and neuromyelitis optica has not been well studied. Our aim was to investigate the potential of ultra-high-field MR imaging to distinguish MS from neuromyelitis optica and to characterize tissue injury associated with iron pathology within lesions. MATERIALS AND METHODS: Twenty-one patients with MS and 21 patients with neuromyelitis optica underwent 7T high-resolution 2D-gradient-echo-T2 and 3D-susceptibility-weighted imaging. An in-house-developed algorithm was used to reconstruct quantitative susceptibility mapping from SWI. Lesions were classified as iron-laden if they demonstrated hypointensity on gradient-echo-T2 -weighted images and/or SWI and hyperintensity on quantitative susceptibility mapping. Lesions were considered non-iron-laden if they were hyperintense on gradient-echo-T2 and isointense or hyperintense on quantitative susceptibility mapping. RESULTS: Of 21 patients with MS, 19 (90.5%) demonstrated at least 1 quantitative susceptibility mapping-hyperintense lesion, and 11/21 (52.4%) had iron-laden lesions. No quantitative susceptibility mapping-hyperintense or iron-laden lesions were observed in any patients with neuromyelitis optica. Iron-laden and non-iron-laden lesions could each be further characterized into 2 distinct patterns based on lesion signal and morphology on gradient-echo-T2 /SWI and quantitative susceptibility mapping. In MS, most lesions (n = 262, 75.9% of all lesions) were hyperintense on gradient-echo T2 and isointense on quantitative susceptibility mapping (pattern A), while a small minority (n = 26, 7.5% of all lesions) were hyperintense on both gradient-echo-T2 and quantitative susceptibility mapping (pattern B). Iron-laden lesions (n = 57, 16.5% of all lesions) were further classified as nodular (n = 22, 6.4%, pattern C) or ringlike (n = 35, 10.1%, pattern D). CONCLUSIONS: Ultra-high-field MR imaging may be useful in distinguishing MS from neuromyelitis optica. Different patterns related to iron and noniron pathology may provide in vivo insight into the pathophysiology of lesions in MS."],["dc.identifier.doi","10.3174/ajnr.A4729"],["dc.identifier.eissn","1936-959X"],["dc.identifier.isi","000380362600006"],["dc.identifier.issn","0195-6108"],["dc.identifier.pmid","27012298"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78324"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Soc Neuroradiology"],["dc.relation.issn","1936-959X"],["dc.relation.issn","0195-6108"],["dc.title","Iron and Non-Iron-Related Characteristics of Multiple Sclerosis and Neuromyelitis Optica Lesions at 7T MRI"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2015Conference Abstract
    [["dc.bibliographiccitation.journal","Multiple Sclerosis Journal"],["dc.bibliographiccitation.volume","21"],["dc.contributor.author","Schumacher, Sophie"],["dc.contributor.author","Pache, Florence"],["dc.contributor.author","Behrens, J."],["dc.contributor.author","Dusek, Petr"],["dc.contributor.author","Harms, L."],["dc.contributor.author","Ruprecht, Klemens"],["dc.contributor.author","Nytrova, P."],["dc.contributor.author","Chawla, Sanjeev"],["dc.contributor.author","Niendorf, T."],["dc.contributor.author","Kister, Ilya"],["dc.contributor.author","Paul, Friedemann"],["dc.contributor.author","Ge, Y."],["dc.contributor.author","Wuerfel, J."],["dc.contributor.author","Sinnecker, Tim"],["dc.date.accessioned","2018-11-07T09:52:01Z"],["dc.date.available","2018-11-07T09:52:01Z"],["dc.date.issued","2015"],["dc.format.extent","185"],["dc.identifier.isi","000365729400327"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/36032"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Sage Publications Ltd"],["dc.publisher.place","London"],["dc.relation.conference","31st Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS)"],["dc.relation.eventlocation","Barcelona, SPAIN"],["dc.relation.issn","1477-0970"],["dc.relation.issn","1352-4585"],["dc.title","Periventricular venous density is normal in neuromyelitis optica - preliminary data from a 7T MRI study"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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