Now showing 1 - 7 of 7
  • 2016Journal Article
    [["dc.bibliographiccitation.firstpage","31"],["dc.bibliographiccitation.journal","International Journal of Women's Health"],["dc.contributor.author","Hijazi, Sameh"],["dc.contributor.author","Leitsmann, Conrad"],["dc.date.accessioned","2021-06-01T10:48:33Z"],["dc.date.available","2021-06-01T10:48:33Z"],["dc.date.issued","2016"],["dc.identifier.doi","10.2147/IJWH.S94956"],["dc.identifier.eissn","1179-1411"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/85973"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.relation.eissn","1179-1411"],["dc.title","Clinical significance of video-urodynamic in female recurrent urinary tract infections"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2016Journal Article
    [["dc.bibliographiccitation.firstpage","66"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Urology Annals"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Hijazi, Sameh"],["dc.contributor.author","Echtle, Dieter"],["dc.contributor.author","Hasselhof, ViktoriaM"],["dc.contributor.author","Trojan, Lutz"],["dc.contributor.author","Heinrich, Elmar"],["dc.date.accessioned","2020-12-10T18:47:43Z"],["dc.date.available","2020-12-10T18:47:43Z"],["dc.date.issued","2016"],["dc.identifier.doi","10.4103/0974-7796.163795"],["dc.identifier.issn","0974-7796"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78862"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Metal telescopic and Amplatz sheath dilation in nephrolithotomy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2015Conference Abstract
    [["dc.bibliographiccitation.firstpage","S163"],["dc.bibliographiccitation.journal","European Journal of Nuclear Medicine and Molecular Imaging"],["dc.bibliographiccitation.lastpage","S164"],["dc.bibliographiccitation.volume","42"],["dc.contributor.author","Meller, Birgit"],["dc.contributor.author","Sahlmann, Carsten-Oliver"],["dc.contributor.author","Hijazi, Sameh"],["dc.contributor.author","Bouter, Caroline"],["dc.contributor.author","Trojan, Lutz"],["dc.contributor.author","Meller, J."],["dc.contributor.author","Thelen, Paul"],["dc.date.accessioned","2018-11-07T09:50:50Z"],["dc.date.available","2018-11-07T09:50:50Z"],["dc.date.issued","2015"],["dc.identifier.isi","000363013201287"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/35785"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","New york"],["dc.relation.conference","28th Annual Congress of the European-Association-of-Nuclear-Medicine (EANM)"],["dc.relation.eventlocation","Hamburg, GERMANY"],["dc.relation.issn","1619-7089"],["dc.relation.issn","1619-7070"],["dc.title","Increase of PSMA Expression by Androgen Deprivation"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2017Journal Article
    [["dc.bibliographiccitation.firstpage","625"],["dc.bibliographiccitation.journal","International Journal of Women's Health"],["dc.bibliographiccitation.lastpage","630"],["dc.bibliographiccitation.volume","Volume 9"],["dc.contributor.author","Hijazi, Sameh"],["dc.contributor.author","Echtle, Dieter"],["dc.contributor.author","Aboumarzouk, Omar M"],["dc.contributor.author","Heinrich, Elmar"],["dc.date.accessioned","2021-06-01T10:48:32Z"],["dc.date.available","2021-06-01T10:48:32Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.2147/IJWH.S134239"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/85972"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.relation.eissn","1179-1411"],["dc.title","Abdominal sacrocolpopexy with Pelvicol xenograft and concomitant Burch colposuspension"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2015Journal Article
    [["dc.bibliographiccitation.firstpage","1934"],["dc.bibliographiccitation.issue","16"],["dc.bibliographiccitation.journal","The Prostate"],["dc.bibliographiccitation.lastpage","1940"],["dc.bibliographiccitation.volume","75"],["dc.contributor.author","Hijazi, Sameh"],["dc.contributor.author","Meller, Birgit"],["dc.contributor.author","Leitsmann, Conrad"],["dc.contributor.author","Strauss, A."],["dc.contributor.author","Meller, J."],["dc.contributor.author","Ritter, Christian Oliver"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Schildhaus, H.-U."],["dc.contributor.author","Trojan, Lutz"],["dc.contributor.author","Sahlmann, Carsten-Oliver"],["dc.date.accessioned","2018-11-07T09:48:43Z"],["dc.date.available","2018-11-07T09:48:43Z"],["dc.date.issued","2015"],["dc.description.abstract","BACKGROUNDThe first evaluation of pelvic extended lymph node dissection (pLND) in oligometastatic prostate cancer (PCa) detected by Ga-68-PSMA PET/CT. METHODSRetrospective analysis of 35 PCa patients underwent Ga-68-PSMA PET/CT affected by biochemical recurrence (BCR) after curative treatment (n=23) or before primary therapy of high-risk PCa (n=12). We performed pLND associated with pathologic imaging in 17 men with nodal oligometastatic PCa. RESULTSIndicative lesions for PCa in PET/CT were detected in 91.4% (32 of 35) of patients. Nodal, bone, visceral (pulmonary), and within the prostate suspected disease were detected in 72% (23 of 32), 16% (5 of 32), 6% (2 of 32), and 47% (15 of 32) of patients, respectively. Median serum PSA in patients with pathological radiotracer uptake in recurrent and high-risk PCa patients was 2.9ng/ml (range 0.18-30) and 19.5ng/ml (range 6-90), respectively. The median number of removed lymph nodes with pLND in recurrent and high-risk PCa was 10 (range 4-17) and 12 (range 8-29) per patient and the median number of positive lymph nodes was 1 (range 1-2) and 3 (2-3) per patient, respectively. In total, two false positive and one false-negative lymph node were found. Diagnostic accuracies per nodal lesion in total of 213 removed nodes: sensitivity, 94%; specificity, 99%; positive predictive value (PPV), 89%, and negative predictive value (NPV), 99.5%. After pLND, 53% (9 of 17) of patients received androgen deprivation therapy and/or radiation therapy and hormonal therapy, while 47% (8 of 17) of patients remained free of any post-surgery therapy. Follow-up PSA remained less than 0.2ng/ml in 82% (14 of 17) of patients. After pLND, immediate BCR (PSA never measured less than 0.2ng/ml) in 18% (3 of 17) of patients was recorded. CONCLUSIONSThis represents the first study of pLND in the setting of nodal oligometastatic PCa detected by Ga-68-PSMA PET/CT. The use of Ga-68-PSMA PET/CT could be to improve the accuracy for the detection of nodal micrometastases. These promising findings need validation in larger studies. Prostate 75:1934-1940, 2015. (c) 2015 Wiley Periodicals, Inc."],["dc.identifier.doi","10.1002/pros.23091"],["dc.identifier.isi","000363219300013"],["dc.identifier.pmid","26356236"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/35365"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","1097-0045"],["dc.relation.issn","0270-4137"],["dc.title","Pelvic lymph node dissection for nodal oligometastatic prostate cancer detected by Ga-68-PSMA-positron emission tomography/computerized tomography"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]
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  • 2016Journal Article
    [["dc.bibliographiccitation.firstpage","776"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","The Prostate"],["dc.bibliographiccitation.lastpage","780"],["dc.bibliographiccitation.volume","76"],["dc.contributor.author","Hijazi, Sameh"],["dc.contributor.author","Meller, Birgit"],["dc.contributor.author","Leitsmann, Conrad"],["dc.contributor.author","Strauss, Arne"],["dc.contributor.author","Ritter, Christian"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Meller, Johannis"],["dc.contributor.author","Trojan, Lutz"],["dc.contributor.author","Sahlmann, Carsten-Oliver"],["dc.date.accessioned","2018-11-07T10:14:00Z"],["dc.date.available","2018-11-07T10:14:00Z"],["dc.date.issued","2016"],["dc.description.abstract","BACKGROUNDOur study is the first evaluation of nodal metastatic prostate cancer (PCa) to mesorectal lymph nodes (MLN) detected by Ga-68-PSMA-PET/CT. METHODSWe retrospectively analyzed 76 consecutive PCa patients who underwent Ga-68-PSMA-PET/CT: 61 PCa patients with biochemical recurrence (BCR) after curative treatment and 15 high-risk PCa before primary therapy. We assessed PET-positive MLN, which are indicative for PCa. RESULTSWe detected PET-positive lesions for PCa in Ga-68-PSMA-PET/CT in 66 of 76 (87%) patients. Nodal disease was imaged in 47 of 66 (71%) patients. Indicative mesorectal nodal lesions for PCa were detected in 12 of 76 (15.8%) patients. The median number of PET-positive MLN was one per patient. Seven of twelve patients had recurrent PCa after radical prostatectomy with a median PSA value of 1.84ng/ml (range 0.31-13). Five of twelve patients had untreated first diagnosed high-risk PCa with median PSA value of 90ng/ml (range 4.6-93) at PET/CT, respectively. For all PET positive MLN a morphological correlate was found in CT (shortest diameter median 4mm [range 4-21]; longest diameter median 7.5mm [range 5-25]). After PET/CT, four patients with recurrent PCa received hormonal therapy, one patient was treated with directed radiation therapy of MLN, one patient received chemotherapy, and one patient was treated with pelvic lymph node dissection. Three high-risk PCa patients received hormonal therapy, and two patients were treated with adjuvant hormonal therapy after radical prostatectomy. CONCLUSIONSDetection and exact location of nodal metastasis for PCa is crucial for the choice of treatment and the patient's prognosis. Ga-68-PSMA-PET/CT seems to improve the detection of nodal metastasis in PCa, especially concerning mesorectal lymph nodes. Prostate 76:776-780, 2016. (c) 2016 Wiley Periodicals, Inc."],["dc.identifier.doi","10.1002/pros.23168"],["dc.identifier.isi","000374860200008"],["dc.identifier.pmid","26880517"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/40540"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1097-0045"],["dc.relation.issn","0270-4137"],["dc.title","See the unseen: Mesorectal lymph node metastases in prostate cancer"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2016Journal Article
    [["dc.bibliographiccitation.firstpage","898"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","European Journal of Nuclear Medicine and Molecular Imaging"],["dc.bibliographiccitation.lastpage","905"],["dc.bibliographiccitation.volume","43"],["dc.contributor.author","Sahlmann, Carsten-Oliver"],["dc.contributor.author","Meller, Birgit"],["dc.contributor.author","Bouter, Caroline"],["dc.contributor.author","Ritter, Christian Oliver"],["dc.contributor.author","Stroebel, Philipp"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Trojan, Lutz"],["dc.contributor.author","Meller, Johannes"],["dc.contributor.author","Hijazi, Sameh"],["dc.date.accessioned","2018-11-07T10:15:18Z"],["dc.date.available","2018-11-07T10:15:18Z"],["dc.date.issued","2016"],["dc.description.abstract","Purpose Binding of Ga-68-PSMA-HBED-CC (Ga-68-PSMA) at prostate cancer (PC) cells increases over time. A biphasic protocol may help separating benign from tumor lesions. The aim of this study was the retrospective evaluation of a diagnostic incremental value of a dual-time point (biphasic) Ga-68-PSMA-PET/CT in patients with prostate cancer. Methods Retrospective analysis of 35 consecutive patients (49-78 years, median 71) with newly diagnosed PC (12/35) or recurrence of PC (23/35). PET/CT (Gemini TF16, Philips) was acquired 1 h and 3 h p. i. of 140-392 MBq (300 MBq median) Ga-68-PSMA, followed by a diagnostic contrast CT. PET findings were correlated with histology or unequivocal CT findings. Semiquantitative PET data (SUVmax, SUV mean) were acquired and target-to-background-ratios (T/B-ratio) were calculated for benign and malign lesions for both time points. Size of lymph nodes (LN) on diagnostic CT was recorded. Statistical analysis was performed for assessment of significant changes of semiquantitative PET-parameters over time and for correlation of size and uptake of lymph nodes. Results One hundred and four lesions were evaluated. Sixty lesions were referenced by histology or unequivocal CT findings, including eight (13.3 %) histopathologically benign lymph nodes, 12 (20 %) histopathologically lymph node metastases, 12 (20 %) primary tumors, three (5 %) local recurrences, and 25 (41.7 %) bone metastases. Forty-four lesions were axillary LN with normal CT-appearance. Benign lesions had significantly lower SUVmax and T/B-ratios compared with malignant findings. Malign lesions showed a significant increase of both parameters over time compared to benign findings. There was no correlation between LN size and SUVmax. The sensitivity, specificity, the positive predictive value and negative predictive value of PET/CT regarding pelvic LN was 94 %, 99 %, 89 %, and 99.5 %, respectively. Conclusions In contrast to benign tissues, the uptake of proven tumor lesions increases on Ga-68-PSMA-PET/CT over time. A biphasic PET-study may lead to a better detection of tumor lesions in unequivocal findings."],["dc.identifier.doi","10.1007/s00259-015-3251-y"],["dc.identifier.isi","000373306800012"],["dc.identifier.pmid","26563122"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/40786"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","1619-7089"],["dc.relation.issn","1619-7070"],["dc.title","Biphasic Ga-68-PSMA-HBED-CC-PET/CT in patients with recurrent and high-risk prostate carcinoma"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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