Stadelmann-Nessler, Christine

[["dc.bibliographiccitation.firstpage","62"],["dc.bibliographiccitation.journal","Parkinsonism & Related Disorders"],["dc.bibliographiccitation.lastpage","65"],["dc.bibliographiccitation.volume","101"],["dc.contributor.author","Bukhari, Syed A."],["dc.contributor.author","Nudelman, Kelly N.H."],["dc.contributor.author","Rumbaugh, Malia"],["dc.contributor.author","Richeson, Pema"],["dc.contributor.author","Fox, Edward J."],["dc.contributor.author","Montine, Kathleen S."],["dc.contributor.author","Aldecoa, Iban"],["dc.contributor.author","Garrido, Alicia"],["dc.contributor.author","Franz, Jonas"],["dc.contributor.author","Stadelmann, Christine"],["dc.contributor.author","Montine, Thomas J."],["dc.date.accessioned","2022-09-01T09:49:46Z"],["dc.date.available","2022-09-01T09:49:46Z"],["dc.date.issued","2022"],["dc.description.sponsorship"," http://dx.doi.org/10.13039/100000864 Michael J. Fox Foundation for Parkinson's Research"],["dc.identifier.doi","10.1016/j.parkreldis.2022.06.017"],["dc.identifier.pii","S1353802022002139"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/113527"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-597"],["dc.relation.issn","1353-8020"],["dc.rights.uri","https://www.elsevier.com/tdm/userlicense/1.0/"],["dc.title","Parkinson's Progression Markers Initiative brain autopsy program"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","168"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Nature Neuroscience"],["dc.bibliographiccitation.lastpage","175"],["dc.bibliographiccitation.volume","24"],["dc.contributor.author","Meinhardt, Jenny"],["dc.contributor.author","Radke, Josefine"],["dc.contributor.author","Dittmayer, Carsten"],["dc.contributor.author","Franz, Jonas"],["dc.contributor.author","Thomas, Carolina"],["dc.contributor.author","Mothes, Ronja"],["dc.contributor.author","Laue, Michael"],["dc.contributor.author","Schneider, Julia"],["dc.contributor.author","Brünink, Sebastian"],["dc.contributor.author","Greuel, Selina"],["dc.contributor.author","Lehmann, Malte"],["dc.contributor.author","Hassan, Olga"],["dc.contributor.author","Aschman, Tom"],["dc.contributor.author","Schumann, Elisa"],["dc.contributor.author","Chua, Robert Lorenz"],["dc.contributor.author","Conrad, Christian"],["dc.contributor.author","Eils, Roland"],["dc.contributor.author","Stenzel, Werner"],["dc.contributor.author","Windgassen, Marc"],["dc.contributor.author","Rößler, Larissa"],["dc.contributor.author","Goebel, Hans-Hilmar"],["dc.contributor.author","Gelderblom, Hans R."],["dc.contributor.author","Martin, Hubert"],["dc.contributor.author","Nitsche, Andreas"],["dc.contributor.author","Schulz-Schaeffer, Walter J."],["dc.contributor.author","Hakroush, Samy"],["dc.contributor.author","Winkler, Martin S."],["dc.contributor.author","Tampe, Björn"],["dc.contributor.author","Scheibe, Franziska"],["dc.contributor.author","Körtvélyessy, Péter"],["dc.contributor.author","Reinhold, Dirk"],["dc.contributor.author","Siegmund, Britta"],["dc.contributor.author","Kühl, Anja A."],["dc.contributor.author","Elezkurtaj, Sefer"],["dc.contributor.author","Horst, David"],["dc.contributor.author","Oesterhelweg, Lars"],["dc.contributor.author","Tsokos, Michael"],["dc.contributor.author","Ingold-Heppner, Barbara"],["dc.contributor.author","Stadelmann, Christine"],["dc.contributor.author","Drosten, Christian"],["dc.contributor.author","Corman, Victor Max"],["dc.contributor.author","Radbruch, Helena"],["dc.contributor.author","Heppner, Frank L."],["dc.date.accessioned","2021-04-14T08:27:03Z"],["dc.date.available","2021-04-14T08:27:03Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1038/s41593-020-00758-5"],["dc.identifier.pmid","33257876"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/82152"],["dc.identifier.url","https://mbexc.uni-goettingen.de/literature/publications/97"],["dc.identifier.url","https://rdp.sfb274.de/literature/publications/10"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation","EXC 2067: Multiscale Bioimaging"],["dc.relation","TRR 274: Checkpoints of Central Nervous System Recovery"],["dc.relation","TRR 274 | B01: The role of inflammatory cytokine signaling for efficient remyelination in multiple sclerosis"],["dc.relation.eissn","1546-1726"],["dc.relation.issn","1097-6256"],["dc.relation.workinggroup","RG Stadelmann-Nessler"],["dc.title","Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","887"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","Nature Neuroscience"],["dc.bibliographiccitation.lastpage","899"],["dc.bibliographiccitation.volume","25"],["dc.contributor.author","Merlini, Arianna"],["dc.contributor.author","Haberl, Michael"],["dc.contributor.author","Strauß, Judith"],["dc.contributor.author","Hildebrand, Luisa"],["dc.contributor.author","Genc, Nafiye"],["dc.contributor.author","Franz, Jonas"],["dc.contributor.author","Chilov, Dmitri"],["dc.contributor.author","Alitalo, Kari"],["dc.contributor.author","Flügel-Koch, Cassandra"],["dc.contributor.author","Stadelmann, Christine"],["dc.contributor.author","Flügel, Alexander"],["dc.contributor.author","Odoardi, Francesca"],["dc.date.accessioned","2022-08-19T08:14:13Z"],["dc.date.available","2022-08-19T08:14:13Z"],["dc.date.issued","2022-07"],["dc.description.abstract","The meninges, comprising the leptomeninges (pia and arachnoid layers) and the pachymeninx (dura layer), participate in central nervous system (CNS) autoimmunity, but their relative contributions remain unclear. Here we report on findings in animal models of CNS autoimmunity and in patients with multiple sclerosis, where, in acute and chronic disease, the leptomeninges were highly inflamed and showed structural changes, while the dura mater was only marginally affected. Although dural vessels were leakier than leptomeningeal vessels, effector T cells adhered more weakly to the dural endothelium. Furthermore, local antigen-presenting cells presented myelin and neuronal autoantigens less efficiently, and the activation of autoreactive T cells was lower in dural than leptomeningeal layers, preventing local inflammatory processes. Direct antigen application was required to evoke a local inflammatory response in the dura. Together, our data demonstrate an uneven involvement of the meningeal layers in CNS autoimmunity, in which effector T cell trafficking and activation are functionally confined to the leptomeninges, while the dura remains largely excluded from CNS autoimmune processes."],["dc.identifier.doi","10.1038/s41593-022-01108-3"],["dc.identifier.pmid","35773544"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/113030"],["dc.identifier.url","https://rdp.sfb274.de/literature/publications/71"],["dc.identifier.url","https://mbexc.uni-goettingen.de/literature/publications/510"],["dc.language.iso","en"],["dc.relation","TRR 274: Checkpoints of Central Nervous System Recovery"],["dc.relation","TRR 274 | A03: Checkpoints determining recovery from acute autoimmune CNS grey matter lesions"],["dc.relation","TRR 274 | A04: The role of the meninges in the resolution of acute autoimmune CNS lesions"],["dc.relation","EXC 2067: Multiscale Bioimaging"],["dc.relation.eissn","1546-1726"],["dc.relation.issn","1097-6256"],["dc.relation.workinggroup","RG Flügel"],["dc.relation.workinggroup","RG Odoardi (Echtzeitdarstellung neuroimmunologischer Prozesse)"],["dc.relation.workinggroup","RG Stadelmann-Nessler"],["dc.title","Distinct roles of the meningeal layers in CNS autoimmunity"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]