Schaeper, Jannis Justus

[["dc.bibliographiccitation.firstpage","4142"],["dc.bibliographiccitation.issue","17"],["dc.bibliographiccitation.journal","Soft Matter"],["dc.bibliographiccitation.lastpage","4154"],["dc.bibliographiccitation.volume","16"],["dc.contributor.author","Komorowski, Karlo"],["dc.contributor.author","Sztucki, Michael"],["dc.contributor.author","Sharpnack, Lewis"],["dc.contributor.author","Brehm, Gerrit"],["dc.contributor.author","Köster, Sarah"],["dc.contributor.author","Salditt, Tim"],["dc.contributor.author","Schaeper, Jannis"],["dc.date.accessioned","2020-04-23T12:28:28Z"],["dc.date.available","2020-04-23T12:28:28Z"],["dc.date.issued","2020"],["dc.description.abstract","We have used time-resolved small-angle X-ray scattering (SAXS) to study the adhesion of lipid vesicles in the electrostatic strong-coupling regime induced by divalent ions. The bilayer structure and the interbilayer distance dw between adhered vesicles was studied for different DOPC:DOPS mixtures varying the surface charge density of the membrane, as well as for different divalent ions, such as Ca2+, Sr2+, and Zn2+. The results are in good agreement with the strong coupling theory predicting the adhesion state and the corresponding like-charge attraction based on ion-correlations. Using SAXS combined with the stopped-flow rapid mixing technique, we find that in highly charged bilayers the adhesion state is only of transient nature, and that the adhering vesicles subsequently transform to a phase of multilamellar vesicles, again with an inter-bilayer distance according to the theory of strong binding. Aside from the stopped-flow SAXS instrumentations used primarily for these results, we also evaluate microfluidic sample environments for vesicle SAXS in view of future extension of this work."],["dc.identifier.doi","10.1039/D0SM00259C"],["dc.identifier.pmid","32319505"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/64290"],["dc.identifier.url","https://mbexc.uni-goettingen.de/literature/publications/186"],["dc.identifier.url","https://sfb1286.uni-goettingen.de/literature/publications/72"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.relation","EXC 2067: Multiscale Bioimaging"],["dc.relation","SFB 1286: Quantitative Synaptologie"],["dc.relation","SFB 1286 | A02: Bestimmung der Struktur synaptischer Organellen durch Röntgenbeugungs- und Bildgebungsverfahren"],["dc.relation","SFB 1286 | B02: Ein in vitro-Verfahren zum Verständnis der struktur-organisierenden Rolle des Vesikel-Clusters"],["dc.relation.eissn","1744-6848"],["dc.relation.issn","1744-683X"],["dc.relation.orgunit","Institut für Röntgenphysik"],["dc.relation.workinggroup","RG Köster (Cellular Biophysics)"],["dc.relation.workinggroup","RG Salditt (Structure of Biomolecular Assemblies and X-Ray Physics)"],["dc.rights","CC BY-NC 3.0"],["dc.subject.gro","x-ray scattering"],["dc.subject.gro","membrane biophysics"],["dc.subject.gro","microfluidics"],["dc.title","Vesicle adhesion in the electrostatic strong-coupling regime studied by time-resolved small-angle X-ray scattering"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]