Frischkorn, Sebastian

[["dc.bibliographiccitation.firstpage","1"],["dc.bibliographiccitation.journal","Journal of Biomolecular NMR"],["dc.bibliographiccitation.lastpage","9"],["dc.contributor.author","Reddy, Jithender G."],["dc.contributor.author","Pratihar, Supriya"],["dc.contributor.author","Frischkorn, Sebastian"],["dc.contributor.author","Becker, Stefan"],["dc.contributor.author","Griesinger, Christian"],["dc.contributor.author","Lee, Donghan"],["dc.date.accessioned","2018-01-17T11:30:39Z"],["dc.date.available","2018-01-17T11:30:39Z"],["dc.date.issued","2017"],["dc.description.abstract","Molecular dynamics play a significant role in how molecules perform their function. A critical method that provides information on dynamics, at the atomic level, is NMR-based relaxation dispersion (RD) experiments. RD experiments have been utilized for understanding multiple biological processes occurring at micro-to-millisecond time, such as enzyme catalysis, molecular recognition, ligand binding and protein folding. Here, we applied the recently developed high-power RD concept to the Carr-Purcell-Meiboom-Gill sequence (extreme CPMG; E-CPMG) for the simultaneous detection of fast and slow dynamics. Using a fast folding protein, gpW, we have shown that previously inaccessible kinetics can be accessed with the improved precision and efficiency of the measurement by using this experiment."],["dc.identifier.doi","10.1007/s10858-017-0155-0"],["dc.identifier.pmid","29188417"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/11678"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.eissn","1573-5001"],["dc.title","Simultaneous determination of fast and slow dynamics in molecules using extreme CPMG relaxation dispersion experiments"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]