Atypical Anorexia in a Male Patient Accompanied by Strong Obsessive-compulsive Symptoms Successfully Treated with Naltrexone

We present a patient diagnosed with atypical anorexia accompanied by mainly food intake-related OCD-like symptoms who failed to respond to clomipramine, risperidone, fluoxetine and olanzapine treatment, cognitive behavioural therapy (CBT) and psychodynamic psychotherapy. Naltrexone at a dose of 50 mg/d was added to the current medication consisting of fluoxetine and olanzapine, which resulted in a significant reduction of obsessive-compulsive symptoms as measured by Yale-Brown obsessive-compulsive scale (Y-BOCS) after 8 weeks into naltrexone treatment. The patient's eating behaviour normalised, resulting in an increased body mass index and substantial improvement in his quality of life.