Pre-Operative Versus Post-Operative Radiosurgery of Brain Metastases-Volumetric and Dosimetric Impact of Treatment Sequence and Margin Concept

ISSN
2072-6694
Date Issued
2019-03-01
Author(s)
Tonndorf-Martini, Eric
Schmitt, Daniela
Weber, Dorothea
Celik, Aylin
Dresel, Thorsten
Bernhardt, Denise
Lang, Kristin
Hoegen, Philipp
Adeberg, Sebastian
Paul, Angela
Debus, Jürgen
DOI
10.3390/cancers11030294
Abstract
Pre-operative radiosurgery (SRS) preceding the resection of brain metastases promises to circumvent limitations of post-operative cavity SRS. It minimizes uncertainties regarding delineation and safety margins and could reduce dose exposure of the healthy brain (HB).