Orientation Contrast Enhancement Modulated by Differential Long-Range Interactions in Visual Cortex

Recently Sillito and coworkers18,12 demonstrated that Stimulation beyond the classical receptive field (RF) can not only modulate, but radically change a neuron\’s response to oriented stimuli. They revealed that patch-suppressed cells when stimulated with contrasting orientations inside and outside their classical RF can strongly respond to stimuli oriented orthogonal to their nominal preferred orientation.