Robotic Radiosurgery for Brain Metastases Diagnosed With Either SPACE or MPRAGE Sequence (CYBER-SPACE)-A Single-Center Prospective Randomized Trial

ISSN
0148-396X
Date Issued
2019
Author(s)
Paul, Angela
Bernhardt, Denise
Lang, Kristin
Welzel, Thomas
Sprave, Tanja
Hommertgen, Adriane
Krisam, Johannes
Schmitt, Daniela
Klüter, Sebastian
Schubert, Kai
Klose, Christina
Kieser, Meinhard
Debus, Jürgen
DOI
10.1093/neuros/nyy026
Abstract
Stereotactic radiosurgery (SRS) of brain metastases (BM) is recommended in oligometastatic scenarios as a less toxic treatment alternative to whole-brain radiotherapy. Recent findings support SRS for patients with multiple (>3) BM. Furthermore, advances in MR imaging have facilitated the detection of very small BM, as advances in SRS technology have facilitated the highly conformal and simultaneous treatment of multiple target lesions.