Myelinophagy: Schwann cells dine in

ISSN
1540-8140
0021-9525
Date Issued
2015
Author(s)
DOI
10.1083/jcb.201506039
Abstract
When nerve injury occurs, the axon and myelin fragments distal to the injury site have to be cleared away before repair. In this issue, Gomez-Sanchez et al. (2015; J. Cell Biol. http://dx.doi.org/10.1083/jcb.201503019) find that clearance of the damaged myelin within Schwann cells occurs not by phagocytosis but rather via selective autophagy, in a process they term "myelinophagy."
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