Endophenazines A similar to D, new phenazine antibiotics from the athropod associated endosymbiont Streptomyces anulatus II. Structure elucidation

A detailed screening of the secondary metabolite pattern produced by different athropod associated strains of the species Streptomyces anulatus resulted in the isolation and structure elucidation of the endophenazines Asimilar toD (2, 4similar to6). The structures were assigned by spectroscopic methods and chemical transformations. 4 represents a chromophoric system based on a phenazin-7-one, 5 and 6 are new 5, 10-dihydrophenazine derivatives.