Radical cyclizations terminated by Ir-catalyzed hydrogen atom transfer

ISSN
0002-7863
Date Issued
2011-01-26
Author(s)
Gansäuer, Andreas
Shi, Lei
DOI
10.1021/ja109362m
Abstract
A system for coupling catalytic radical cyclization and Ir-catalyzed hydrogen atom transfer (HAT) is described. It is essential that the HAT catalyst activates H(2) quickly and is not a hydrogenation catalyst. Vaska's complex was found to fulfill both purposes efficiently.