Import of Proteins into Peroxisomes

eroxisomes are organelles equipped with enzymes for lipid metabolism and hydrogen-peroxide-based respiration. Though many details of their metabolism are understood today, basic aspects concerning their biogenesis, including translocation of peroxisomal proteins into and through the peroxisomal membrane, still remain unknown. Nevertheless, the past years have brought forth a wealth of detailed information on the proteins required for proper biogenesis of peroxisomes. This review focuses on the basic principles and on recent developments in the field of peroxisome biogenesis. More comprehensive or specialized reviews can be found in the reference list.