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Response to Comment on "Principles of connectivity among morphologically defined cell types in adult neocortex"
ISSN
0036-8075
Date Issued
2016
Author(s)
Jiang, Xiaolong
Shen, Shan
Reimer, Jacob
Cadwell, Cathryn R.
Berens, Philipp
Patel, Saumil
Denfield, George H.
Froudarakis, Emmanouil
Li, Shuang
Walker, Edgar
Tolias, Andreas S.
DOI
10.1126/science.aaf6102
Abstract
The critique of Barth et al centers on three points: (i) the completeness of our study is overstated; (ii) the connectivity matrix we describe is biased by technical limitations of our brain-slicing and multipatching methods; and (iii) our cell classification scheme is arbitrary and we have simply renamed previously identified interneuron types. We address these criticisms in our Response.