Buergers, Ralf

[["dc.bibliographiccitation.issue","32"],["dc.bibliographiccitation.journal","International Journal of Implant Dentistry"],["dc.bibliographiccitation.volume","3"],["dc.contributor.author","Wassmann, Torsten"],["dc.contributor.author","Kreis, Stefan"],["dc.contributor.author","Behr, Michael"],["dc.contributor.author","Buergers, Ralf"],["dc.date.accessioned","2019-07-09T11:44:25Z"],["dc.date.available","2019-07-09T11:44:25Z"],["dc.date.issued","2017"],["dc.description.abstract","This study aims to investigate bacterial adhesion on different titanium and ceramic implant surfaces, to correlate these findings with surface roughness and surface hydrophobicity, and to define the predominant factor for bacterial adhesion for each material. Zirconia and titanium specimens with different surface textures and wettability (5.0 mm in diameter, 1.0 mm in height) were prepared. Surface roughness was measured by perthometer (R a ) and atomic force microscopy, and hydrophobicity according to contact angles by computerized image analysis. Bacterial suspensions of Streptococcus sanguinis and Staphylococcus epidermidis were incubated for 2 h at 37 °C with ten test specimens for each material group and quantified with fluorescence dye CytoX-Violet and an automated multi-detection reader. Variations in surface roughness (R a ) did not lead to any differences in adhering S. epidermidis, but higher R a resulted in increased S. sanguinis adhesion. In contrast, higher bacterial adhesion was observed on hydrophobic surfaces than on hydrophilic surfaces for S. epidermidis but not for S. sanguinis. The potential to adhere S. sanguinis was significantly higher on ceramic surfaces than on titanium surfaces; no such preference could be found for S. epidermidis. Both surface roughness and wettability may influence the adhesion properties of bacteria on biomaterials; in this context, the predominant factor is dependent on the bacterial species. Wettability was the predominant factor for S. epidermidis and surface texture for S. sanguinis. Zirconia did not show any lower bacterial colonization potential than titanium. Arithmetical mean roughness values R a (measured by stylus profilometer) are inadequate for describing surface roughness with regard to its potential influence on microbial adhesion."],["dc.identifier.doi","10.1186/s40729-017-0093-3"],["dc.identifier.pmid","28714053"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14756"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/59009"],["dc.notes.intern","Merged from goescholar"],["dc.notes.intern","In goescholar not merged with http://resolver.sub.uni-goettingen.de/purl?gs-1/15179 but duplicate"],["dc.rights","CC BY 4.0"],["dc.rights.access","openAccess"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","The influence of surface texture and wettability on initial bacterial adhesion on titanium and zirconium oxide dental implants"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2109"],["dc.bibliographiccitation.issue","24"],["dc.bibliographiccitation.journal","Spine"],["dc.bibliographiccitation.lastpage","2115"],["dc.bibliographiccitation.volume","35"],["dc.contributor.author","Devito, Dennis P."],["dc.contributor.author","Kaplan, Leon"],["dc.contributor.author","Dietl, Rupert"],["dc.contributor.author","Pfeiffer, Michael"],["dc.contributor.author","Horne, Dale"],["dc.contributor.author","Silberstein, Boris"],["dc.contributor.author","Hardenbrook, Mitchell"],["dc.contributor.author","Kiriyanthan, George"],["dc.contributor.author","Barzilay, Yair"],["dc.contributor.author","Bruskin, Alexander"],["dc.contributor.author","Sackerer, Dieter"],["dc.contributor.author","Alexandrovsky, Vitali"],["dc.contributor.author","Stueer, Carsten"],["dc.contributor.author","Burger, Ralf"],["dc.contributor.author","Maeurer, Johannes"],["dc.contributor.author","Gordon, Donald G."],["dc.contributor.author","Schoenmayr, Robert"],["dc.contributor.author","Friedlander, Alon"],["dc.contributor.author","Knoller, Nachshon"],["dc.contributor.author","Schmieder, Kirsten"],["dc.contributor.author","Pechlivanis, Ioannis"],["dc.contributor.author","Kim, In-Se"],["dc.contributor.author","Meyer, Bernhard"],["dc.contributor.author","Shoham, Moshe"],["dc.date.accessioned","2018-11-07T08:36:56Z"],["dc.date.available","2018-11-07T08:36:56Z"],["dc.date.issued","2010"],["dc.description.abstract","Study Design. Retrospective, multicenter study of robotically-guided spinal implant insertions. Clinical acceptance of the implants was assessed by intraoperative radiograph, and when available, postoperative computed tomography (CT) scans were used to determine placement accuracy. Objective. To verify the clinical acceptance and accuracy of robotically-guided spinal implants and compare to those of unguided free-hand procedures. Summary of Background Data. SpineAssist surgical robot has been used to guide implants and guide-wires to predefined locations in the spine. SpineAssist which, to the best of the authors' knowledge, is currently the sole robot providing surgical assistance in positioning tools in the spine, guided over 840 cases in 14 hospitals, between June 2005 and June 2009. Methods. Clinical acceptance of 3271 pedicle screws and guide-wires inserted in 635 reported cases was assessed by intraoperative fluoroscopy, where placement accuracy of 646 pedicle screws inserted in 139 patients was measured using postoperative CT scans. Results. Screw placements were found to be clinically acceptable in 98% of the cases when intraoperatively assessed by fluoroscopic images. Measurements derived from postoperative CT scans demonstrated that 98.3% of the screws fell within the safe zone, where 89.3% were completely within the pedicle and 9% breached the pedicle by up to 2 mm. The remaining 1.4% of the screws breached between 2 and 4 mm, while only 2 screws (0.3%) deviated by more than 4 mm from the pedicle wall. Neurologic deficits were observed in 4 cases yet, following revisions, no permanent nerve damage was encountered, in contrast to the 0.6% to 5% of neurologic damage reported in the literature. Conclusion. SpineAssist offers enhanced performance in spinal surgery when compared to free-hand surgeries, by increasing placement accuracy and reducing neurologic risks. In addition, 49% of the cases reported herein used a percutaneous approach, highlighting the contribution of SpineAssist in procedures without anatomic landmarks."],["dc.identifier.doi","10.1097/BRS.0b013e3181d323ab"],["dc.identifier.isi","000284265100002"],["dc.identifier.pmid","21079498"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/18423"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Lippincott Williams & Wilkins"],["dc.relation.issn","0362-2436"],["dc.title","Clinical Acceptance and Accuracy Assessment of Spinal Implants Guided With SpineAssist Surgical Robot Retrospective Study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","371"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","The International Journal of Prosthodontics"],["dc.bibliographiccitation.lastpage","373"],["dc.bibliographiccitation.volume","28"],["dc.contributor.author","Papavasileiou, Dimitrios"],["dc.contributor.author","Behr, Michael"],["dc.contributor.author","Gosau, Martin"],["dc.contributor.author","Gerlach, Till"],["dc.contributor.author","Buergers, Ralf"],["dc.date.accessioned","2018-11-07T09:54:57Z"],["dc.date.available","2018-11-07T09:54:57Z"],["dc.date.issued","2015"],["dc.description.abstract","This study investigated subgingival pen-implant biofilm formation on four luting agents (Kerr Temp Bond, Harvard Dental Harvard Cement, 3M ESPE RelyX Unicem, and Kuraray Panavia F 2.0) under realistic in situ conditions. Samples of the luting agents were positioned in the subgingival area of healing abutments, and the biofilm accumulation on the samples at the interface between luting agent and titanium and on the smooth titanium surface was investigated using scanning electron microscopy. In comparison to plane titanium surfaces, interfaces between implant abutment, cement, and suprastructure showed an increased bacterial accumulation and should therefore be regarded as predisposing substrates for pen-implant biofilm formation."],["dc.identifier.isi","000359510400007"],["dc.identifier.pmid","26218019"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/36648"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Quintessence Publishing Co Inc"],["dc.relation.issn","1942-4426"],["dc.relation.issn","0893-2174"],["dc.title","Pen-implant Biofilm Formation on Luting Agents Used for Cementing Implant-Supported Fixed Restorations: A Preliminary In Vivo Study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","118"],["dc.bibliographiccitation.journal","Annals of Anatomy"],["dc.bibliographiccitation.lastpage","124"],["dc.bibliographiccitation.volume","217"],["dc.contributor.author","Krohn, Sebastian"],["dc.contributor.author","Brockmeyer, Phillipp"],["dc.contributor.author","Kubein-Meesenburg, Dietmar"],["dc.contributor.author","Kirschneck, Christian"],["dc.contributor.author","Buergers, Ralf"],["dc.date.accessioned","2020-12-10T14:14:50Z"],["dc.date.available","2020-12-10T14:14:50Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1016/j.aanat.2018.01.007"],["dc.identifier.issn","0940-9602"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/71517"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Elongated styloid process in patients with temporomandibular disorders — Is there a link?"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2225"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","European Journal of Radiology"],["dc.bibliographiccitation.lastpage","2230"],["dc.bibliographiccitation.volume","85"],["dc.contributor.author","Krohn, Sebastian"],["dc.contributor.author","Gersdorff, Nikolaus"],["dc.contributor.author","Wassmann, Torsten"],["dc.contributor.author","Merboldt, Klaus-Dietmar"],["dc.contributor.author","Joseph, Arun A."],["dc.contributor.author","Buergers, Ralf"],["dc.contributor.author","Frahm, Jens"],["dc.date.accessioned","2018-11-07T10:05:09Z"],["dc.date.available","2018-11-07T10:05:09Z"],["dc.date.issued","2016"],["dc.description.abstract","The purpose of this study was to develop and evaluate a novel method for real-time MRI of TMJ function at high temporal resolution and with two different contrasts. Real-time MRI was based on undersampled radial fast low angle shot (FLASH) acquisitions with iterative image reconstruction by regularized nonlinear inversion. Real-time MRI movies with T1 contrast were obtained with use of a radiofrequency-spoiled FLASH sequence, while movies with T2/T1 contrast employed a gradient-refocused FLASH version. TMJ function was characterized in 40 randomly selected volunteers by sequential 20 s acquisitions of both the right and left joint during voluntary opening and closing of the mouth (in a medial, central and lateral oblique sagittal section perpendicular to the long axis of the condylar head). All studies were performed on a commercial MRI system at 3 T using the standard head coil, while online reconstruction was achieved with a bypass computer fully integrated into the MRI system. As a first result, real-time MRI studies of the right and left TMJ were successfully performed in all 40 subjects (80 joints) within a total examination time per subject of only 15 min. Secondly, at an in-plane resolution of 0.75 mm and 5 mm section thickness, the achieved temporal resolution was 66.7 ms per image or 15 frames per second. Thirdly, both T1-weighted and T2/T1-weighted real-time MRI movies provided information about TMJ function such as disc position, condyle mobility and disc-condyle relationship. While T1 contrast offers a better delineation of structures during rapid jaw movements, T2/T1 contrast was rated superior for characterizing the articular disc. In conclusion, the proposed real-time MRI method may become a robust and efficient tool for the clinical assessment of TMJ function. (C) 2016 Elsevier Ireland Ltd. All rights reserved."],["dc.identifier.doi","10.1016/j.ejrad.2016.10.020"],["dc.identifier.isi","000389511400011"],["dc.identifier.pmid","27842671"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/38846"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Ireland Ltd"],["dc.relation.issn","1872-7727"],["dc.relation.issn","0720-048X"],["dc.title","Real-time MRI of the temporomandibular joint at 15 frames per second-A feasibility study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","655"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Acta Neurochirurgica"],["dc.bibliographiccitation.lastpage","661"],["dc.bibliographiccitation.volume","152"],["dc.contributor.author","Kantelhardt, Sven Rainer"],["dc.contributor.author","Bock, Hans Christoph"],["dc.contributor.author","Siam, Laila"],["dc.contributor.author","Larsen, Joerg"],["dc.contributor.author","Burger, Ralf"],["dc.contributor.author","Schillinger, Wolfgang"],["dc.contributor.author","Bockermann, Volker"],["dc.contributor.author","Rohde, Veit"],["dc.contributor.author","Giese, Alf"],["dc.date.accessioned","2018-11-07T08:44:14Z"],["dc.date.available","2018-11-07T08:44:14Z"],["dc.date.issued","2010"],["dc.description.abstract","In contrast to other regions of the human spine, dorsal fixation with rods and pedicle screws is comparatively rarely performed in the cervical spine. Although this technique provides a higher mechanical strength than the more frequently used lateral mass screws, many surgeons fear the relatively high rate of misplacements. This higher incidence is mainly due to the complex vertebral anatomy in this spinal segment. For correct screw placement, the availability of an immediate and efficient intra-operative imaging tool to ascertain the accuracy of the pedicle screw hole position would be beneficial. We have previously investigated the usefulness of an intraspinal, specifically, intra-osseous ultrasound technique in the lumbar spine. In this study its accuracy as a means of controlling intrapedicular screw hole positioning has been evaluated in the cervical spine. An endovascular ultrasound transducer was used for the intra-luminal scanning of 54 pedicle screw holes in cadaveric human spine specimens. Twenty-three of these had been intentionally misplaced (cortex breached). The resulting image files were assessed by three investigators blinded to both the procedure and the corresponding CT findings. The investigators differentiated correctly between adequately and poorly placed pedicle screw holes in 96% of cases. False negatives and false positives both occurred in no more than 1.8% of cases. Intrapedicular ultrasonography of pedicle screw holes in the cervical spine is a promising technique for the intra-operative assessment of bore hole placement and may increase operative safety and postoperative outcome in posterior cervical fusion surgery."],["dc.identifier.doi","10.1007/s00701-009-0447-6"],["dc.identifier.isi","000275945600013"],["dc.identifier.pmid","19597760"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?goescholar/4182"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/20152"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","Wien"],["dc.relation.issn","0001-6268"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Intra-osseous ultrasound for pedicle screw positioning in the subaxial cervical spine: an experimental study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","672"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Brain Pathology"],["dc.bibliographiccitation.lastpage","677"],["dc.bibliographiccitation.volume","21"],["dc.contributor.author","Gutenberg, Angelika"],["dc.contributor.author","Brandis, Almuth"],["dc.contributor.author","Hong, Bujung"],["dc.contributor.author","Gunawan, Bastian"],["dc.contributor.author","Enders, Christina"],["dc.contributor.author","Schaefer, Inga-Marie"],["dc.contributor.author","Burger, Ralf"],["dc.contributor.author","Ostertag, Helmut"],["dc.contributor.author","Gaab, Michael"],["dc.contributor.author","Krauss, Joachim K."],["dc.contributor.author","Fuezesi, Laszlo"],["dc.date.accessioned","2018-11-07T08:50:20Z"],["dc.date.available","2018-11-07T08:50:20Z"],["dc.date.issued","2011"],["dc.description.abstract","Primary papillary tumors of the central nervous system and particularly the pineal region are rare. Papillary tumor of the pineal region (PTPR) is a recently described neoplasm that has been formally recognized in the 2007 World Health Organization Classification of Tumors of the Nervous System. Because of their rarity, further pheno- and genotypical observations as well as therapeutic experience are necessary to differentiate PTPR from other primary or secondary papillary tumors of this region. We herein present three cases of PTPR characterized by local recurrence in two of them. Primary and recurrent tumors were analyzed by immunohistochemistry and comparative genomic hybridization (CGH). From our results clonal chromosomal aberrations can be postulated which seem to be a feasible tool to differentiate PTPRs from other primary or secondary papillary tumors of this region."],["dc.identifier.doi","10.1111/j.1750-3639.2011.00493.x"],["dc.identifier.isi","000296907600007"],["dc.identifier.pmid","21470326"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/21671"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1015-6305"],["dc.title","Common Molecular Cytogenetic Pathway in Papillary Tumors of the Pineal Region (PTPR)"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1081"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Cellular and Molecular Life Sciences"],["dc.bibliographiccitation.lastpage","1096"],["dc.bibliographiccitation.volume","71"],["dc.contributor.author","Schminke, Boris"],["dc.contributor.author","Muhammad, Hayat"],["dc.contributor.author","Bode, Christa"],["dc.contributor.author","Sadowski, Boguslawa"],["dc.contributor.author","Gerter, Regina"],["dc.contributor.author","Gersdorff, Nikolaus"],["dc.contributor.author","Buergers, Ralf"],["dc.contributor.author","Monsonego-Ornan, Efrat"],["dc.contributor.author","Rosen, Vicki"],["dc.contributor.author","Miosge, Nicolai"],["dc.date.accessioned","2018-11-07T09:43:22Z"],["dc.date.available","2018-11-07T09:43:22Z"],["dc.date.issued","2014"],["dc.description.abstract","Discoidin domain receptor 1 (DDR-1)-deficient mice exhibited a high incidence of osteoarthritis (OA) in the temporomandibular joint (TMJ) as early as 9 weeks of age. They showed typical histological signs of OA, including surface fissures, loss of proteoglycans, chondrocyte cluster formation, collagen type I upregulation, and atypical collagen fibril arrangements. Chondrocytes isolated from the TMJs of DDR-1-deficient mice maintained their osteoarthritic characteristics when placed in culture. They expressed high levels of runx-2 and collagen type I, as well as low levels of sox-9 and aggrecan. The expression of DDR-2, a key factor in OA, was increased. DDR-1-deficient chondrocytes from the TMJ were positively influenced towards chondrogenesis by a three-dimensional matrix combined with a runx-2 knockdown or stimulation with extracellular matrix components, such as nidogen-2. Therefore, the DDR-1 knock-out mouse can serve as a novel model for temporomandibular disorders, such as OA of the TMJ, and will help to develop new treatment options, particularly those involving tissue regeneration."],["dc.identifier.doi","10.1007/s00018-013-1436-8"],["dc.identifier.isi","000331653900010"],["dc.identifier.pmid","23912900"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/34171"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","Basel"],["dc.relation.issn","1420-9071"],["dc.relation.issn","1420-682X"],["dc.title","A discoidin domain receptor 1 knock-out mouse as a novel model for osteoarthritis of the temporomandibular joint"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","579"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Clinical Oral Investigations"],["dc.bibliographiccitation.lastpage","587"],["dc.bibliographiccitation.volume","21"],["dc.contributor.author","Rödiger, Matthias"],["dc.contributor.author","Heinitz, Arthur"],["dc.contributor.author","Bürgers, Ralf"],["dc.contributor.author","Rinke, Sven"],["dc.date.accessioned","2018-10-09T07:49:18Z"],["dc.date.available","2018-10-09T07:49:18Z"],["dc.date.issued","2017-03"],["dc.description.abstract","This study focused on the clinical investigation of the internal and marginal fit of CAD/CAM-fabricated zirconia single crowns produced via conventional and digital impression techniques.In a private practice, 20 molar teeth, one from each of 20 patients, were prepared with a circumferential 1.0-mm deep chamfer and an occlusal reduction of 1.5 mm. Conventional impression (CI) taking with a polyvinylsiloxane material (Aquasil Monophase + Aquasil XLV; Dentsply, Konstanz, Germany) and intraoral scanning (IS) (Cara TRIOS; Heraeus, Hanau, Germany) of each of the preparations was performed, and then two respective zirconia copings per tooth were produced (20 crowns per group). The marginal and internal fit of the restorations was evaluated employing a replica technique. For statistical analysis, a pairwise comparison (Wilcoxon rank test) was performed. Zirconia single crowns produced with the IS technique revealed a statistically significant better precision of internal fit only in specific areas (chamfer area/occlusal area). The evaluation of marginal fit showed no significant differences between the two groups. All restorations of both groups offered internal and marginal gaps within the postulated clinical tolerance ranges. CAD/CAM-fabricated zirconia single crowns produced with CI and IS techniques offer adequate marginal and internal precision. However, the IS technique provides lower internal gaps in some specific areas. The clinical precision of fit of restorations produced with a CI and an IS technique appeared to be equivalent. Therefore, the IS technique can be rated as a suitable alternative for the manufacturing of single crowns."],["dc.fs.pkfprnr","67999"],["dc.identifier.doi","10.1007/s00784-016-1924-y"],["dc.identifier.fs","626847"],["dc.identifier.pmid","27469102"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/15900"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.eissn","1436-3771"],["dc.title","Fitting accuracy of zirconia single crowns produced via digital and conventional impressions - a clinical comparative study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1453"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","Journal of Cranio-Maxillofacial Surgery"],["dc.bibliographiccitation.lastpage","1462"],["dc.bibliographiccitation.volume","44"],["dc.contributor.author","Ettl, Tobias"],["dc.contributor.author","Weindler, Janet"],["dc.contributor.author","Gosau, Martin"],["dc.contributor.author","Mueller, Steffen"],["dc.contributor.author","Hautmann, Matthias"],["dc.contributor.author","Zeman, Florian"],["dc.contributor.author","Koller, Michael T."],["dc.contributor.author","Papavasileiou, Dimitrios"],["dc.contributor.author","Buergers, Ralf"],["dc.contributor.author","Driemel, Oliver"],["dc.contributor.author","Schneider, Isabel"],["dc.contributor.author","Klingelhoeffer, Christoph"],["dc.contributor.author","Meier, Johannes"],["dc.contributor.author","Wahlmann, Ulrich"],["dc.contributor.author","Reichert, Torsten E."],["dc.date.accessioned","2018-11-07T10:09:21Z"],["dc.date.available","2018-11-07T10:09:21Z"],["dc.date.issued","2016"],["dc.description.abstract","Purpose: To study implant-based prosthetic rehabilitation of head and neck cancer patients with focus on implant survival and quality of life. Materials and methods: The prospective observational study presents preliminary results of 29 edentulous head neck cancer patients (20 patients after radiotherapy) with 165 OsseoSpeed implants. Implant success after 1-year follow-up was evaluated by means of the Albrektsson criteria. Quality of life was analysed with the EORTC QLQ-C30, QLQ-H&N35, and OHIP 14 questionnaires. Results: The overall implant survival rate after 1 year was 95.2% (157/165). Implant success measured by the Albrektsson criteria showed a lower success rate of 86.7% (143/165), mainly because of peri-implant marginal bone loss with a mean of 0.8 mm after 1 year. Xerostomia (p = 0.008), implant insertion within the radiation target volume (p = 0.09), implantation in transplanted bone (p = 0.05), and smoking (p = 0.041) were the main reasons for implant failure, followed by D4 bone quality, maxillary implant site, and insufficient primary stability. Speaking, swallowing, eating, as well as social integration and individual self-confidence had considerably improved 1 year after denture placement compared to before treatment. Conclusion: Implant-based prosthetic rehabilitation of head and neck cancer patients is possible at a calculable risk and significantly improves patients' quality of life. (C) 2016 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved."],["dc.description.sponsorship","DENTSPLY Implants, Molndal, Sweden [D-2008-44]"],["dc.identifier.doi","10.1016/j.jcms.2016.07.016"],["dc.identifier.isi","000384776400051"],["dc.identifier.pmid","27519660"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/39635"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Churchill Livingstone"],["dc.relation.issn","1878-4119"],["dc.relation.issn","1010-5182"],["dc.title","Impact of radiotherapy on implant-based prosthetic rehabilitation in patients with head and neck cancer: A prospective observational study on implant survival and quality of life-Preliminary results"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]