Options
Abd El Wahed, Ahmed
Loading...
Preferred name
Abd El Wahed, Ahmed
Official Name
Abd El Wahed, Ahmed
Alternative Name
Abd El Wahed, A.
Main Affiliation
ORCID
Now showing 1 - 10 of 55
2013Journal Article [["dc.bibliographiccitation.artnumber","e71642"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","PLoS ONE"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Abd El Wahed, Ahmed"],["dc.contributor.author","El-Deeb, Ayman"],["dc.contributor.author","El-Tholoth, Mohamed"],["dc.contributor.author","Abd El Kader, Hanaa"],["dc.contributor.author","Ahmed, Abeer"],["dc.contributor.author","Hassan, Sayed"],["dc.contributor.author","Hoffmann, Bernd"],["dc.contributor.author","Haas, Bernd"],["dc.contributor.author","Shalaby, Mohamed A."],["dc.contributor.author","Hufert, Frank T."],["dc.contributor.author","Weidmann, Manfred"],["dc.date.accessioned","2018-11-07T09:21:11Z"],["dc.date.available","2018-11-07T09:21:11Z"],["dc.date.issued","2013"],["dc.description.abstract","Foot-and-mouth disease (FMD) is a trans-boundary viral disease of livestock, which causes huge economic losses and constitutes a serious infectious threat for livestock farming worldwide. Early diagnosis of FMD helps to diminish its impact by adequate outbreak management. In this study, we describe the development of a real-time reverse transcription recombinase polymerase amplification (RT-RPA) assay for the detection of FMD virus (FMDV). The FMDV RT-RPA design targeted the 3D gene of FMDV and a 260 nt molecular RNA standard was used for assay validation. The RT-RPA assay was fast (4-10 minutes) and the analytical sensitivity was determined at 1436 RNA molecules detected by probit regression analysis. The FMDV RT-RPA assay detected RNA prepared from all seven FMDV serotypes but did not detect classical swine fever virus or swine vesicular disease virus. The FMDV RT-RPA assay was used in the field during the recent FMD outbreak in Egypt. In clinical samples, reverse transcription polymerase chain reaction (RT-PCR) and RT-RPA showed a diagnostic sensitivity of 100% and 98%, respectively. In conclusion, FMDV RT-RPA was quicker and much easier to handle in the field than real-time RT-PCR. Thus RT-RPA could be easily implemented to perform diagnostics at quarantine stations or farms for rapid spot-of-infection detection."],["dc.identifier.doi","10.1371/journal.pone.0071642"],["dc.identifier.isi","000324527300028"],["dc.identifier.pmid","23977101"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/10753"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/29055"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Public Library Science"],["dc.relation.issn","1932-6203"],["dc.rights","CC BY 3.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/3.0"],["dc.title","A Portable Reverse Transcription Recombinase Polymerase Amplification Assay for Rapid Detection of Foot-and-Mouth Disease Virus"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]Details DOI PMID PMC WOS2021Journal Article Research Paper [["dc.bibliographiccitation.firstpage","134"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","Veterinary Sciences"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Yehia, Nahed"],["dc.contributor.author","Eldemery, Fatma"],["dc.contributor.author","Arafa, Abdel-Satar"],["dc.contributor.author","Abd El Wahed, Ahmed"],["dc.contributor.author","El Sanousi, Ahmed"],["dc.contributor.author","Weidmann, Manfred"],["dc.contributor.author","Shalaby, Mohamed"],["dc.date.accessioned","2021-08-12T07:46:06Z"],["dc.date.available","2021-08-12T07:46:06Z"],["dc.date.issued","2021"],["dc.description.abstract","The H9N2 subtype of avian influenza A virus (aIAV) is circulating among birds worldwide, leading to severe economic losses. H9N2 cocirculation with other highly pathogenic aIAVs has the potential to contribute to the rise of new strains with pandemic potential. Therefore, rapid detection of H9 aIAVs infection is crucial to control virus spread. A qualitative reverse transcription recombinase polymerase amplification (RT-RPA) assay for the detection of aIAV subtype H9N2 was developed. All results were compared to the gold standard (real-time reverse transcription polymerase chain reaction (RT-PCR)). The RT-RPA assay was designed to detect the hemagglutinin (HA) gene of H9N2 by testing three pairs of primers and a probe. A serial concentration between 106 and 100 EID50 (50% embryo infective dose)/mL was applied to calculate the analytical sensitivity. The H9 RT-RPA assay was highly sensitive as the lowest concentration point of a standard range at one EID50/mL was detected after 5 to 8 min. The H9N2 RT-RPA assay was highly specific as nucleic acid extracted from H9 negative samples and from other avian pathogens were not cross detected. The diagnostic sensitivity when testing clinical samples was 100% for RT-RPA and RT-PCR. In conclusion, H9N2 RT-RPA is a rapid sensitive and specific assay that easily operable in a portable device for field diagnosis of aIAV H9N2."],["dc.description.abstract","The H9N2 subtype of avian influenza A virus (aIAV) is circulating among birds worldwide, leading to severe economic losses. H9N2 cocirculation with other highly pathogenic aIAVs has the potential to contribute to the rise of new strains with pandemic potential. Therefore, rapid detection of H9 aIAVs infection is crucial to control virus spread. A qualitative reverse transcription recombinase polymerase amplification (RT-RPA) assay for the detection of aIAV subtype H9N2 was developed. All results were compared to the gold standard (real-time reverse transcription polymerase chain reaction (RT-PCR)). The RT-RPA assay was designed to detect the hemagglutinin (HA) gene of H9N2 by testing three pairs of primers and a probe. A serial concentration between 106 and 100 EID50 (50% embryo infective dose)/mL was applied to calculate the analytical sensitivity. The H9 RT-RPA assay was highly sensitive as the lowest concentration point of a standard range at one EID50/mL was detected after 5 to 8 min. The H9N2 RT-RPA assay was highly specific as nucleic acid extracted from H9 negative samples and from other avian pathogens were not cross detected. The diagnostic sensitivity when testing clinical samples was 100% for RT-RPA and RT-PCR. In conclusion, H9N2 RT-RPA is a rapid sensitive and specific assay that easily operable in a portable device for field diagnosis of aIAV H9N2."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2021"],["dc.identifier.doi","10.3390/vetsci8070134"],["dc.identifier.pii","vetsci8070134"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/88619"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-448"],["dc.relation.eissn","2306-7381"],["dc.relation.orgunit","Abteilung Mikrobiologie und Tierhygiene"],["dc.rights","CC BY 4.0"],["dc.title","Reverse Transcription Recombinase Polymerase Amplification Assay for Rapid Detection of Avian Influenza Virus H9N2 HA Gene"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]Details DOI2020Journal Article [["dc.bibliographiccitation.journal","Frontiers in Veterinary Science"],["dc.bibliographiccitation.volume","7"],["dc.contributor.author","Roller, Marco"],["dc.contributor.author","Hansen, Sören"],["dc.contributor.author","Knauf-Witzens, Tobias"],["dc.contributor.author","Oelemann, Walter M. R."],["dc.contributor.author","Czerny, Claus-Peter"],["dc.contributor.author","Abd El Wahed, Ahmed"],["dc.contributor.author","Goethe, Ralph"],["dc.date.accessioned","2021-04-14T08:30:11Z"],["dc.date.available","2021-04-14T08:30:11Z"],["dc.date.issued","2020"],["dc.description.abstract","Mycobacterium avium subspecies paratuberculosis (MAP) is the causative agent of paratuberculosis (ParaTB or Johne's disease), a contagious, chronic and typically fatal enteric disease of domestic and non-domestic ruminants. Clinically affected animals present wasting and emaciation. However, MAP can also infect non-ruminant animal species with less specific signs. Zoological gardens harbor various populations of diverse animal species, which are managed on limited space at higher than natural densities. Hence, they are predisposed to endemic trans-species pathogen distribution. Information about the incidence and prevalence of MAP infections in zoological gardens and the resulting potential threat to exotic and endangered species are rare. Due to unclear pathogenesis, chronicity of disease as well as the unknown cross-species accuracy of diagnostic tests, diagnosis and surveillance of MAP and ParaTB is challenging. Differentiation between uninfected shedders of ingested bacteria; subclinically infected individuals; and preclinically diseased animals, which may subsequently develop clinical signs after long incubation periods, is crucial for the interpretation of positive test results in animals and the resulting consequences in their management. This review summarizes published data from the current literature on occurrence of MAP infection and disease in susceptible and affected zoo animal species as well as the applied diagnostic methods and measures. Clinical signs indicative for ParaTB, pathological findings and reports on detection, transmission and epidemiology in zoo animals are included. Furthermore, case reports were re-evaluated for incorporation into accepted consistent terminologies and case definitions."],["dc.identifier.doi","10.3389/fvets.2020.572724"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/83135"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.publisher","Frontiers Media S.A."],["dc.relation.eissn","2297-1769"],["dc.rights","http://creativecommons.org/licenses/by/4.0/"],["dc.title","Mycobacterium avium Subspecies paratuberculosis Infection in Zoo Animals: A Review of Susceptibility and Disease Process"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]Details DOI2019Journal Article [["dc.bibliographiccitation.firstpage","104764"],["dc.bibliographiccitation.journal","Data in Brief"],["dc.bibliographiccitation.volume","27"],["dc.contributor.author","Hansen, Sören"],["dc.contributor.author","Pessôa, Rodrigo"],["dc.contributor.author","Nascimento, Andrezza"],["dc.contributor.author","El-Tholoth, Mohamed"],["dc.contributor.author","Abd El Wahed, Ahmed"],["dc.contributor.author","Sanabani, Sabri S."],["dc.date.accessioned","2020-12-10T14:23:28Z"],["dc.date.available","2020-12-10T14:23:28Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1016/j.dib.2019.104764"],["dc.identifier.issn","2352-3409"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/16736"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/71937"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Dataset of the microbiome composition in skin lesions caused by lumpy skin disease virus via 16s rRNA massive parallel sequencing"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]Details DOI2013Journal Article [["dc.bibliographiccitation.journal","PLoS currents"],["dc.bibliographiccitation.volume","5"],["dc.contributor.author","Abd El Wahed, Ahmed"],["dc.contributor.author","Patel, Pranav"],["dc.contributor.author","Heidenreich, Doris"],["dc.contributor.author","Hufert, Frank T."],["dc.contributor.author","Weidmann, Manfred"],["dc.date.accessioned","2019-07-09T11:40:12Z"],["dc.date.available","2019-07-09T11:40:12Z"],["dc.date.issued","2013"],["dc.description.abstract","The emergence of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in the eastern Mediterranean and imported cases to Europe has alerted public health authorities. Currently, detection of MERS-CoV in patient samples is done by real-time RT-PCR. Samples collected from suspected cases are sent to highly-equipped centralized laboratories for screening. A rapid point-of-care test is needed to allow more widespread mobile detection of the virus directly from patient material. In this study, we describe the development of a reverse transcription isothermal Recombinase Polymerase Amplification (RT-RPA) assay for the identification of MERS-CoV. A partial nucleocapsid gene RNA molecular standard of MERS-coronavirus was used to determine the assay sensitivity. The isothermal (42°C) MERS-CoV RT-RPA was as sensitive as real-time RT-PCR (10 RNA molecules), rapid (3-7 minutes) and mobile (using tubescanner weighing 1kg). The MERS-CoV RT-RPA showed cross-detection neither of any of the RNAs of several coronaviruses and respiratory viruses affecting humans nor of the human genome. The developed isothermal real-time RT-RPA is ideal for rapid mobile molecular MERS-CoV monitoring in acute patients and may also facilitate the search for the animal reservoir of MERS-CoV."],["dc.identifier.doi","10.1371/currents.outbreaks.62df1c7c75ffc96cd59034531e2e8364"],["dc.identifier.fs","601231"],["dc.identifier.pmid","24459611"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/10752"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/58113"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","2157-3999"],["dc.rights","CC BY 3.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/3.0"],["dc.title","Reverse transcription recombinase polymerase amplification assay for the detection of middle East respiratory syndrome coronavirus."],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]Details DOI PMID PMC2017Journal Article [["dc.bibliographiccitation.firstpage","363"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","Viruses"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Schmitt, Anne"],["dc.contributor.author","Gan, Li"],["dc.contributor.author","Abd El Wahed, Ahmed"],["dc.contributor.author","Shi, Tingchuan"],["dc.contributor.author","Ellerbrok, Heinz"],["dc.contributor.author","Kaup, Franz-Josef"],["dc.contributor.author","Stahl-Hennig, Christiane"],["dc.contributor.author","Mätz-Rensing, Kerstin"],["dc.date.accessioned","2020-12-10T18:47:25Z"],["dc.date.available","2020-12-10T18:47:25Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.3390/v9120363"],["dc.identifier.eissn","1999-4915"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78756"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.publisher","MDPI"],["dc.relation.eissn","1999-4915"],["dc.rights","https://creativecommons.org/licenses/by/4.0/"],["dc.title","Dynamics of Pathological and Virological Findings During Experimental Calpox Virus Infection of Common Marmosets (Callithrix jacchus)"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]Details DOI2015Journal Article [["dc.bibliographiccitation.firstpage","45"],["dc.bibliographiccitation.journal","Journal of Virological Methods"],["dc.bibliographiccitation.lastpage","49"],["dc.bibliographiccitation.volume","223"],["dc.contributor.author","Yehia, Nahed"],["dc.contributor.author","Arafa, Abdel-Satar"],["dc.contributor.author","Abd El Wahed, Ahmed"],["dc.contributor.author","El-Sanousi, Ahmed A."],["dc.contributor.author","Weidmann, Manfred"],["dc.contributor.author","Shalaby, Mohamed A."],["dc.date.accessioned","2021-06-01T10:49:45Z"],["dc.date.available","2021-06-01T10:49:45Z"],["dc.date.issued","2015"],["dc.identifier.doi","10.1016/j.jviromet.2015.07.011"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/86399"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.relation.issn","0166-0934"],["dc.title","Development of reverse transcription recombinase polymerase amplification assay for avian influenza H5N1 HA gene detection"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]Details DOI2021Journal Article Research Paper [["dc.bibliographiccitation.firstpage","351"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Vaccines"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Eltom, Kamal H."],["dc.contributor.author","Althoff, Anna Christina"],["dc.contributor.author","Hansen, Sören"],["dc.contributor.author","Böhlken-Fascher, Susanne"],["dc.contributor.author","Yousif, Ausama"],["dc.contributor.author","El-Sheikh, Hussein A."],["dc.contributor.author","ElWakeel, Ahmed A."],["dc.contributor.author","Elgamal, Mahmoud A."],["dc.contributor.author","Mossa, Hadeer M."],["dc.contributor.author","Abd El Wahed, Ahmed"],["dc.contributor.author","Aboul-Soud, Emad A."],["dc.contributor.author","Wolff, Janika"],["dc.contributor.author","Korthase, Christian"],["dc.contributor.author","Hoffmann, Bernd"],["dc.contributor.author","Adam, Nabawia M."],["dc.contributor.author","Abdelaziz, Sanaa A."],["dc.contributor.author","Shalaby, Mohamed A."],["dc.date.accessioned","2021-06-01T09:42:43Z"],["dc.date.available","2021-06-01T09:42:43Z"],["dc.date.issued","2021"],["dc.description.abstract","The genus capripoxvirus (CaPV), family Poxviridae, includes three virus species: goatpox virus (GPV), sheeppox virus (SPV) and lumpy skin disease virus (LSDV). CaPV causes disease outbreaks with consequent economic losses in Africa and the Middle East. LSDV has recently spread to Southeast Europe. As CaPVs share 96–97% genetic similarity along the length of the entire genome and are difficult to distinguish using serological assays, simple, reliable and fast methods for diagnosis and species differentiation are crucial in cases of disease outbreak. The present study aimed to develop a field-applicable CaPV differentiation method. Nanopore technology was used for whole genome sequencing. A local database of complete CaPV genomes and partial sequences of three genes (RPO30, P32 and GPCR) was established for offline Basic Local Alignment Search Tool (BLAST). Specificities of 98.04% in whole genome and 97.86% in RPO30 gene runs were obtained among the three virus species, while other databases were less specific. The total run time was shortened to approximately 2 h. Functionality of the developed procedure was proved by samples with high host background sequences. Reliable differentiation options for the quality and capacity of hardware, and sample quality of suspected cases, were derived from these findings. The whole workflow can be performed rapidly with a mobile suitcase laboratory and mini-computer, allowing application at the point-of-need with limited resource settings."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2021"],["dc.identifier.doi","10.3390/vaccines9040351"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/85330"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.relation.eissn","2076-393X"],["dc.relation.orgunit","Abteilung Mikrobiologie und Tierhygiene"],["dc.rights","CC BY 4.0"],["dc.title","Differentiation of Capripox Viruses by Nanopore Sequencing"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]Details DOI2021Journal Article [["dc.bibliographiccitation.firstpage","2623"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","Microorganisms"],["dc.bibliographiccitation.volume","9"],["dc.contributor.affiliation","Ssekitoleko, Judah; 1College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala P. O. Box 7062, Uganda; jsekitoleko2810@gmail.com (J.S.); lonzyo@yahoo.com (L.O.); erujoseph@yahoo.com (J.E.)"],["dc.contributor.affiliation","Ojok, Lonzy; 1College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala P. O. Box 7062, Uganda; jsekitoleko2810@gmail.com (J.S.); lonzyo@yahoo.com (L.O.); erujoseph@yahoo.com (J.E.)"],["dc.contributor.affiliation","Abd El Wahed, Ahmed; 4Institute of Animal Hygiene and Veterinary Public Health, Leipzig University, D-04103 Leipzig, Germany"],["dc.contributor.affiliation","Erume, Joseph; 1College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala P. O. Box 7062, Uganda; jsekitoleko2810@gmail.com (J.S.); lonzyo@yahoo.com (L.O.); erujoseph@yahoo.com (J.E.)"],["dc.contributor.affiliation","Amanzada, Ahmad; 5Department of Gastroenterology and Gastrointestinal Oncology, University Medical Centre Goettingen, D-37075 Goettingen, Germany; ahmad.amanzada@med.uni-goettingen.de"],["dc.contributor.affiliation","Eltayeb, ElSagad; 6Ibn Sina Specialised Hospital, Mohammed Najeeb St., Khartoum 11560, Sudan; sagadgady@yahoo.com"],["dc.contributor.affiliation","Eltom, Kamal H.; 8Unit of Animal Health and Safety of Animal Products, Institute for Studies and Promotion of Animal Exports, University of Khartoum, Shambat, Khartoum North 13314, Sudan; keltom@daad-alumni.de"],["dc.contributor.affiliation","Okuni, Julius Boniface; 1College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala P. O. Box 7062, Uganda; jsekitoleko2810@gmail.com (J.S.); lonzyo@yahoo.com (L.O.); erujoseph@yahoo.com (J.E.)"],["dc.contributor.author","Ssekitoleko, Judah"],["dc.contributor.author","Ojok, Lonzy"],["dc.contributor.author","Abd El Wahed, Ahmed"],["dc.contributor.author","Erume, Joseph"],["dc.contributor.author","Amanzada, Ahmad"],["dc.contributor.author","Eltayeb, ElSagad"],["dc.contributor.author","Eltom, Kamal H."],["dc.contributor.author","Okuni, Julius Boniface"],["dc.contributor.editor","Dow, Coad Thomas"],["dc.date.accessioned","2022-01-11T14:08:04Z"],["dc.date.available","2022-01-11T14:08:04Z"],["dc.date.issued","2021"],["dc.date.updated","2022-02-09T13:19:52Z"],["dc.description.abstract","To propose a solution for control of Mycobacterium avium subsp. paratuberculosis (MAP) infections in animals as well as in humans, and develop effective prevention, diagnostic and treatment strategies, it is essential to understand the molecular mechanisms of MAP pathogenesis. In the present review, we discuss the mechanisms utilised by MAP to overcome the host defense system to achieve the virulence status. Putative MAP virulence genes are mentioned and their probable roles in view of other mycobacteria are discussed. This review provides information on MAP strain diversity, putative MAP virulence factors and highlights the knowledge gaps regarding MAP virulence mechanisms that may be important in control and prevention of paratuberculosis."],["dc.description.abstract","To propose a solution for control of Mycobacterium avium subsp. paratuberculosis (MAP) infections in animals as well as in humans, and develop effective prevention, diagnostic and treatment strategies, it is essential to understand the molecular mechanisms of MAP pathogenesis. In the present review, we discuss the mechanisms utilised by MAP to overcome the host defense system to achieve the virulence status. Putative MAP virulence genes are mentioned and their probable roles in view of other mycobacteria are discussed. This review provides information on MAP strain diversity, putative MAP virulence factors and highlights the knowledge gaps regarding MAP virulence mechanisms that may be important in control and prevention of paratuberculosis."],["dc.identifier.doi","10.3390/microorganisms9122623"],["dc.identifier.eissn","2076-2607"],["dc.identifier.pii","microorganisms9122623"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/97925"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-507"],["dc.publisher","MDPI"],["dc.relation.eissn","2076-2607"],["dc.rights","Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/)."],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0/"],["dc.title","Mycobacterium avium subsp. paratuberculosis Virulence: A Review"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]Details DOI2019Journal Article [["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Parasites & Vectors"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Khan, Md Anik Ashfaq"],["dc.contributor.author","Chowdhury, Rajashree"],["dc.contributor.author","Nath, Rupen"],["dc.contributor.author","Hansen, Sören"],["dc.contributor.author","Nath, Progga"],["dc.contributor.author","Maruf, Shomik"],["dc.contributor.author","Abd El Wahed, Ahmed"],["dc.contributor.author","Mondal, Dinesh"],["dc.date.accessioned","2020-12-10T18:39:05Z"],["dc.date.available","2020-12-10T18:39:05Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1186/s13071-019-3771-6"],["dc.identifier.eissn","1756-3305"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/16641"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77539"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0/"],["dc.title","Imported cutaneous leishmaniasis: molecular investigation unveils Leishmania major in Bangladesh"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]Details DOI