Werner, Gerald

[["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Journal of the American College of Cardiology"],["dc.bibliographiccitation.volume","35"],["dc.contributor.author","Werner, Gerald"],["dc.contributor.author","Richartz, B. M."],["dc.contributor.author","Schunemann, S."],["dc.date.accessioned","2018-11-07T10:41:58Z"],["dc.date.available","2018-11-07T10:41:58Z"],["dc.date.issued","2000"],["dc.format.extent","536A"],["dc.identifier.isi","000085209702039"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/46668"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.publisher.place","New york"],["dc.relation.issn","0735-1097"],["dc.title","Determinants of acute and long-term survival in 245 patients with infective endocarditis"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","The FASEB Journal"],["dc.bibliographiccitation.volume","19"],["dc.contributor.author","Neu, E."],["dc.contributor.author","Michailov, Michael Ch."],["dc.contributor.author","Welscher, Ursula"],["dc.contributor.author","Werner, Gerald"],["dc.date.accessioned","2018-11-07T11:17:23Z"],["dc.date.available","2018-11-07T11:17:23Z"],["dc.date.issued","2005"],["dc.format.extent","A215"],["dc.identifier.isi","000227610701355"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/54793"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Federation Amer Soc Exp Biol"],["dc.publisher.place","Bethesda"],["dc.relation.conference","Experimental Biology 2005 Meeting/35th International Congress of Physiological Sciences"],["dc.relation.eventlocation","San Diego, CA"],["dc.relation.issn","0892-6638"],["dc.title","On comparative physiology of oscillations in vascular myocytes"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","European Heart Journal"],["dc.bibliographiccitation.volume","35"],["dc.contributor.author","Yilmaz, A."],["dc.contributor.author","Maier, Lars. S."],["dc.contributor.author","Schroeder, S."],["dc.contributor.author","Fleischmann, Claus"],["dc.contributor.author","Werner, Gerald"],["dc.contributor.author","Pfafferott, C."],["dc.contributor.author","Haimerl, J."],["dc.contributor.author","Elsaesser, Albrecht"],["dc.contributor.author","Ott, R."],["dc.contributor.author","Scholz, Karl Heinrich"],["dc.date.accessioned","2018-11-07T09:35:35Z"],["dc.date.available","2018-11-07T09:35:35Z"],["dc.date.issued","2014"],["dc.format.extent","724"],["dc.identifier.isi","000343001304275"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/32418"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press"],["dc.publisher.place","Oxford"],["dc.relation.eventlocation","Barcelona, SPAIN"],["dc.relation.issn","1522-9645"],["dc.relation.issn","0195-668X"],["dc.title","Beneficial effect of thrombusaspiration in patients with STEMI - Results from the FITT-STEMI multicenter trial"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Journal of the Neurological Sciences"],["dc.bibliographiccitation.volume","357"],["dc.contributor.author","Neu, E."],["dc.contributor.author","Traub, M."],["dc.contributor.author","Michailov, Michael Ch."],["dc.contributor.author","Schumitz, H."],["dc.contributor.author","Dahlheim, H."],["dc.contributor.author","Werner, Gerald"],["dc.contributor.author","Foltinova, Janka"],["dc.contributor.author","Birkenbihl, P."],["dc.contributor.author","Danler-Oppl, H."],["dc.contributor.author","Senn, T. N."],["dc.contributor.author","Welscher, Ursula"],["dc.contributor.author","Moro, N."],["dc.date.accessioned","2018-11-07T09:50:10Z"],["dc.date.available","2018-11-07T09:50:10Z"],["dc.date.issued","2015"],["dc.format.extent","E206"],["dc.identifier.doi","10.1016/j.jns.2015.08.709"],["dc.identifier.isi","000384634801073"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/35654"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Bv"],["dc.publisher.place","Amsterdam"],["dc.relation.eventlocation","Santiago, CHILE"],["dc.relation.issn","1878-5883"],["dc.relation.issn","0022-510X"],["dc.title","On neuro-vascular factors of idiopathic hypertension including cerebral apoplexy"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Journal of the American College of Cardiology"],["dc.bibliographiccitation.volume","43"],["dc.contributor.author","Ferrari, M."],["dc.contributor.author","Hellige, Gerhard"],["dc.contributor.author","Schlosser, M."],["dc.contributor.author","Werner, Gerald"],["dc.contributor.author","Frerichs, Inez"],["dc.contributor.author","Damm, C."],["dc.contributor.author","Guyenot, V."],["dc.contributor.author","Figulla, H. R."],["dc.date.accessioned","2018-11-07T10:50:24Z"],["dc.date.available","2018-11-07T10:50:24Z"],["dc.date.issued","2004"],["dc.identifier.doi","10.1016/S0735-1097(04)91833-5"],["dc.identifier.isi","000189388501836"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/48640"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.publisher.place","New york"],["dc.relation.conference","54th Annual Scientific Session of the American-College-of-Cardiology"],["dc.relation.eventlocation","New Orleans, LA"],["dc.relation.eventstart","2004"],["dc.title","Percutaneous aortic valve replacement with a self-expandable stent-valve in the beating heart: In vivo stress testing in an animal model"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","The Journal of Physiological Sciences"],["dc.bibliographiccitation.volume","59"],["dc.contributor.author","Michailov, Michael Ch."],["dc.contributor.author","Neu, Eva"],["dc.contributor.author","Welscher, Ursula"],["dc.contributor.author","Werner, Gerald"],["dc.contributor.author","Foltinova, Janka"],["dc.contributor.author","Senn, Tatjana"],["dc.contributor.author","Seidenbusch, Walter"],["dc.date.accessioned","2018-11-07T08:34:56Z"],["dc.date.available","2018-11-07T08:34:56Z"],["dc.date.issued","2009"],["dc.format.extent","168"],["dc.identifier.isi","000271023101080"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/17942"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","Tokyo"],["dc.relation.issn","1880-6546"],["dc.title","ON MECHANISMS OF GENUINE (IDIOPATHIC) HYPERTENSION AND ARTERIAL MOTOR OSCILLATIONS"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","102"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Herz"],["dc.bibliographiccitation.lastpage","109"],["dc.bibliographiccitation.volume","33"],["dc.contributor.author","Scholz, Karl Heinrich"],["dc.contributor.author","von Knobelsdorff, Georg"],["dc.contributor.author","Ahlersmann, Dorothe"],["dc.contributor.author","Keating, Friederike K."],["dc.contributor.author","Jung, Jens"],["dc.contributor.author","Werner, Gerald"],["dc.contributor.author","Nitsche, Rolf"],["dc.contributor.author","Duwald, Holger"],["dc.contributor.author","Hilgers, Reinhard"],["dc.date.accessioned","2018-11-07T11:17:42Z"],["dc.date.available","2018-11-07T11:17:42Z"],["dc.date.issued","2008"],["dc.description.abstract","Rapid revascularization of the infarct-related artery importantly affects prognosis in the treatment of acute ST elevation myocardial infarction (STEMI).Treatment results can be improved significantly when a STEMI-specific structure of care is created and when systematic quality improvement measures are implemented. The necessary structural measures include establishing or participating in myocardial infarction networks. When local hospitals collaborate in a network, it becomes feasible to offer round-the-clock primary coronary intervention to patients of those participating hospitals that do not have a catheterization laboratory on site. Another important structural step is to acquire and install prehospital twelve-lead ECG systems capable of remote telemetric transmission. This provides a solid basis for diagnosing STEMI with speed and accuracy and can prove to be highly effective in anchoring the chain of alert and treatment. As a consequence, two important goals can be realized: (1) intentionally bypassing the noninterventional hospital, and (2) systematically bypassing the emergency room of the interventional center. Both of these measures entail important time savings. An efficient instrument for improving treatment times is the implementation of a standardized quality improvement process with formalized data collection and analysis as well as with systematic data feedback to all systems and individuals involved in the early phase of treating STEMI patients within the hospital network including the emergency medical responder systems. The positive effect of such data feedback on treatment quality is contingent on the perception by all those involved that the data obtained for each patient are absolutely valid. Thus, those data need to be verifiable and an independent monitoring process should be created. Furthermore, the systematic use of standardized risk scores should be promoted in an effort to compare and adjust patient risk when analyzing network data. It is critically important that all appropriate patients - including those with a high risk of mortality- have access to rapid interventional treatment. Only when the individual risk of treated patients is taken into account will it be possible to compare quality of care and mortality rates. In general,the comparison between different hospitals, systems and regions is highly problematic and not feasible without considering local factors. It harbors the danger of inducing changes in practice in order to compete rather than in order to advance patient care, and thus it may be counterproductive when such a comparison leads to the implication that treatment may have been inferior. Therefore, the comparison of results (e.g.,treatment times and mortality rates) should be undertaken as much as possible within an established system, with the use of a \"before and after\" design. Quality, then, will be defined as a documented consistent effort to improve results, and this approach will be distinctly productive. It is of fundamental importance that the involved hospitals, physicians and emergency staff perceive themselves as a team. The structures and processes outlined above can and should be applied broadly. The necessary resources will need to be provided through political and societal consensus. The multicenter FITT-STEMI project (,,Feedback Intervention and Treatment Times in ST-Elevation Myocardial Infarction\") is currently pursuing such an approach."],["dc.identifier.doi","10.1007/s00059-008-3094-4"],["dc.identifier.isi","000254245400003"],["dc.identifier.pmid","18344028"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/54869"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Urban & Vogel"],["dc.relation.issn","0340-9937"],["dc.title","Optimizing systems of care for patients with acute myocardial infarction. STEMI networks, telemetry ECG, and standardized quality improvement with systematic data feedback"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1326"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Heart"],["dc.bibliographiccitation.lastpage","1331"],["dc.bibliographiccitation.volume","90"],["dc.contributor.author","Ferrari, M."],["dc.contributor.author","Figulla, H. R."],["dc.contributor.author","Schlosser, M."],["dc.contributor.author","Tenner, I."],["dc.contributor.author","Frerichs, Inez"],["dc.contributor.author","Damm, C."],["dc.contributor.author","Guyenot, V."],["dc.contributor.author","Werner, Gerald"],["dc.contributor.author","Hellige, Gerhard"],["dc.date.accessioned","2018-11-07T10:44:17Z"],["dc.date.available","2018-11-07T10:44:17Z"],["dc.date.issued","2004"],["dc.description.abstract","Objectives: To evaluate the feasibility of percutaneous aortic valve replacement without cardiac arrest in animal experiments. Methods: A self expanding nitinol stent, containing pulmonary valves from pigs in its proximal part, was implanted in six pigs (94-118 kg) by means of a 25 French catheter through the left subclavian artery under guidance of fluoroscopy and transoesophageal echocardiography. During stent deployment the original aortic valve was pushed against the aortic wall by the self expanding force of the stent while the new valve was expanded. Results: It was possible to replace the aortic valve in the beating heart in four pigs (67%) with no complication or relevant drop in blood pressure. The procedure failed in two pigs (33%) due to dysfunction of the catheter device in one case and to problems with correct positioning in the left ventricular outflow tract in the other. After successful stent valve implantation, dopamine was infused in doses of 5 mug/kg/min, 10 mug/kg/min, and 15 mug/kg/min. Cardiac output increased from 4.4 to 8.8 l/min and the mean arterial pressure rose from 79 to 105 mm Hg. The maximum peak to peak pressure gradient across the valve carrying stent reached a maximum of 8 mm Hg under dopamine infusion. All pigs were killed six hours after transvascular aortic valve replacement. The chest was opened, and the left ventricle and the ascending aorta were carefully inspected. There were no signs of malfunction of the implant, of damage of the aortic vessel wall, or of obstruction of the coronary ostia. Conclusions: Percutaneous aortic valve replacement with a self expanding nitinol stent in the beating heart is possible. The device was safe under pharmacological stress test. After successful chronic animal experiments, this concept may become a feasible option for treating patients with relevant aortic valve disease but where open heart surgery would be risky."],["dc.identifier.doi","10.1136/hrt.2003.028951"],["dc.identifier.isi","000224477000019"],["dc.identifier.pmid","15486135"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/47235"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","1355-6037"],["dc.title","Transarterial aortic valve replacement with a self expanding stent in pigs"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","848"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","JACC Cardiovascular Interventions"],["dc.bibliographiccitation.lastpage","857"],["dc.bibliographiccitation.volume","5"],["dc.contributor.author","Scholz, Karl Heinrich"],["dc.contributor.author","Maier, Sebastian K. G."],["dc.contributor.author","Jung, Jens"],["dc.contributor.author","Fleischmann, Claus"],["dc.contributor.author","Werner, Gerald"],["dc.contributor.author","Olbrich, Hans G."],["dc.contributor.author","Ahlersmann, Dorothe"],["dc.contributor.author","Keating, Friederike K."],["dc.contributor.author","Jacobshagen, Claudius"],["dc.contributor.author","Moehlis, Hiller"],["dc.contributor.author","Hilgers, Reinhard"],["dc.contributor.author","Maier, Lars. S."],["dc.date.accessioned","2018-11-07T09:07:36Z"],["dc.date.available","2018-11-07T09:07:36Z"],["dc.date.issued","2012"],["dc.description.abstract","Objectives This study sought to evaluate the effect of systematic data analysis and standardized feedback on treatment times and outcome in a prospective multicenter trial. Background Formalized data feedback may reduce treatment times in ST-segment elevation myocardial infarction (STEMI). Methods Over a 15-month period, 1,183 patients presenting with STEMI were enrolled. Six primary percutaneous coronary intervention hospitals in Germany and 29 associated nonpercutaneous coronary intervention hospitals participated. Data from patient contact to balloon inflation were collected and analyzed. Pre-defined quality indicators, including the percentage of patients with pre-announced STEMI, direct handoff in the catheterization laboratory, contact-to-balloon time <90 min, door-to-balloon time <60 min, and door-to-balloon time <30 min were discussed with staff on a quarterly basis. Results Median door-to-balloon time decreased from 71 to 58 min and contact-to-balloon time from 129 to 103 min between the first and the fifth quarter (p < 0.05 for both). Contributing were shorter stays in the emergency department, more direct handoffs from ambulances to the catheterization laboratory (from 22% to 38%, p < 0.05), and a slight increase in the number of patients transported directly to the percutaneous coronary intervention facility (primary transport). One-year mortality was reduced in the total group of patients and in the subgroup of patients with primary transport (p < 0.05). The sharpest fall in mortality was observed in patients with primary transport and TIMI (Thrombolysis In Myocardial Infarction) risk score >= 3 (n = 521) with a decrease in 30-day mortality from 23.1% to 13.3% (p < 0.05) and in 1-year mortality from 25.6% to 16.7% (p < 0.05). Conclusions Formalized data feedback is associated with a reduction in treatment times for STEMI and with an improved prognosis, which is most pronounced in high-risk patients. (Feedback Intervention and Treatment Times in ST-Elevation Myocardial Infarction [ FITT-STEMI]; NCT00794001) (J Am Coll Cardiol Intv 2012; 5: 848-57) (C) 2012 by the American College of Cardiology Foundation"],["dc.identifier.doi","10.1016/j.jcin.2012.04.012"],["dc.identifier.isi","000308071000008"],["dc.identifier.pmid","22917457"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/25837"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.relation.issn","1936-8798"],["dc.title","Reduction in Treatment Times Through Formalized Data Feedback Results From a Prospective Multicenter Study of ST-Segment Elevation Myocardial Infarction"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","European Heart Journal"],["dc.bibliographiccitation.volume","34"],["dc.contributor.author","Koeth, O."],["dc.contributor.author","Maier, Sebastian K. G."],["dc.contributor.author","Fleischmann, Claus"],["dc.contributor.author","Werner, Gerald"],["dc.contributor.author","Maier, Lars. S."],["dc.contributor.author","Olbrich, Hans G."],["dc.contributor.author","Jung, J."],["dc.contributor.author","Scholz, Karl Heinrich"],["dc.date.accessioned","2018-11-07T09:21:32Z"],["dc.date.available","2018-11-07T09:21:32Z"],["dc.date.issued","2013"],["dc.format.extent","75"],["dc.identifier.isi","000327744600265"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/29130"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press"],["dc.publisher.place","Oxford"],["dc.relation.conference","Congress of the European-Society-of-Cardiology (ESC)"],["dc.relation.eventlocation","Amsterdam, NETHERLANDS"],["dc.relation.issn","1522-9645"],["dc.relation.issn","0195-668X"],["dc.title","Current use and clinical benefit of intraaortic balloon support in patients with ST-elevation myocardial infarction complicated by cardiogenic shock"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]