Buchhorn, Gottfried Hans

[["dc.bibliographiccitation.firstpage","992"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","Knee Surgery Sports Traumatology Arthroscopy"],["dc.bibliographiccitation.lastpage","998"],["dc.bibliographiccitation.volume","18"],["dc.contributor.author","Baums, Mike Herbert"],["dc.contributor.author","Geyer, Michael"],["dc.contributor.author","Bueschken, Meike"],["dc.contributor.author","Buchhorn, Gottfried Hans"],["dc.contributor.author","Spahn, Gunter"],["dc.contributor.author","Klinger, Hans-Michael"],["dc.date.accessioned","2018-11-07T08:41:52Z"],["dc.date.available","2018-11-07T08:41:52Z"],["dc.date.issued","2010"],["dc.description.abstract","The aim of the study was to evaluate the time-zero mechanical and footprint properties of a suture-bridge technique for rotator cuff repair in an animal model. Thirty fresh-frozen sheep shoulders were randomly assigned among three investigation groups: (1) cyclic loading, (2) load-to-failure testing, and (3) tendon-bone interface contact pressure measurement. Shoulders were cyclically loaded from 10 to 180 N and displacement to gap formation of 5- and 10-mm at the repair site. Cycles to failure were determined. Additionally, the ultimate tensile strength and stiffness were verified along with the mode of failure. The average contact pressure and pressure pattern were investigated using a pressure-sensitive film system. All of the specimens resisted against 3,000 cycles and none of them reached a gap formation of 10 mm. The number of cycles to 5-mm gap formation was 2,884.5 +/- A 96.8 cycles. The ultimate tensile strength was 565.8 +/- A 17.8 N and stiffness was 173.7 +/- A 9.9 N/mm. The entire specimen presented a unique mode of failure as it is well known in using high strength sutures by pulling them through the tendon. We observed a mean contact pressure of 1.19 +/- A 0.03 MPa, applied on the footprint area. The fundamental results of our study support the use of a suture-bridge technique for optimising the conditions of the healing biology of a reconstructed rotator cuff tendon. Nevertheless, an individual estimation has to be done if using the suture-bridge technique clinically. Further investigation is necessary to evaluate the cell biological healing process in order to achieve further sufficient advancements in rotator cuff repair."],["dc.identifier.doi","10.1007/s00167-009-0941-7"],["dc.identifier.isi","000278931500027"],["dc.identifier.pmid","19826786"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/4969"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/19563"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0942-2056"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Tendon-bone contact pressure and biomechanical evaluation of a modified suture-bridge technique for rotator cuff repair"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","525"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Neuroradiology"],["dc.bibliographiccitation.lastpage","529"],["dc.bibliographiccitation.volume","51"],["dc.contributor.author","Ernstberger, Thorsten"],["dc.contributor.author","Buchhorn, Gottfried"],["dc.contributor.author","Heidrich, Gabert"],["dc.date.accessioned","2018-11-07T08:27:28Z"],["dc.date.available","2018-11-07T08:27:28Z"],["dc.date.issued","2009"],["dc.description.abstract","Introduction Intervertebral spacers are made of different materials, which can affect the postfusion magnetic imaging (MRI) scans. Susceptibility artifacts especially for metallic implants can decrease the image quality. This study aimed to determine whether magnesium as a lightweight and biocompatible metal is suitable as a biomaterial for spinal implants based on its MRI artifacting behavior. Materials and methods To compare artifacting behaviors, we implanted into one porcine cadaveric spine different test spacers made of magnesium, titanium, and carbon-fiber-reinforced polymers (CFRP). All test spacers were scanned using two T1-TSE MRI sequences. The artifact dimensions were traced on all scans and statistically analyzed. Results The total artifact volume and median artifact area of the titanium spacers were statistically significantly larger than magnesium spacers (p<0.001), while magnesium and CFRP spacers produced almost identical artifacting behaviors (p>0.05). Conclusion Our results suggest that spinal implants made with magnesium alloys will behave more like CFRP devices in MRI scans. Given its osseoconductive potential as a metal, implant alloys made with magnesium would combine the advantages to the two principal spacer materials currently used but without their limitations, at least in terms of MRI artifacting."],["dc.identifier.doi","10.1007/s00234-009-0537-4"],["dc.identifier.isi","000269013900004"],["dc.identifier.pmid","19468722"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6176"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/16212"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0028-3940"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Artifacts in spine magnetic resonance imaging due to different intervertebral test spacers: an in vitro evaluation of magnesium versus titanium and carbon-fiber-reinforced polymers as biomaterials"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","145"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Toxicology"],["dc.bibliographiccitation.lastpage","154"],["dc.bibliographiccitation.volume","190"],["dc.contributor.author","Katzer, A."],["dc.contributor.author","Hockertz, S."],["dc.contributor.author","Buchhorn, Gottfried Hans"],["dc.contributor.author","Loehr, J. F."],["dc.date.accessioned","2018-11-07T10:36:53Z"],["dc.date.available","2018-11-07T10:36:53Z"],["dc.date.issued","2003"],["dc.description.abstract","Contact of wear particles with body fluids can result in widespread dissemination of extractable constituents from joint implants. The ann of this in vitro study is to clarify whether there is a mutagenic and/or carcinogenic risk from CoCrMo and Ti6Al wear particles. Particles of a representative size were produced by fretting; toxicity and mutagenicity were investigated using the salmonella/microsome test according to AMES and the V79-HGPRT Test (Chinese Hamster Fibroblasts). To obtain the greatest possible elution of all constituents the metallic wear particles were extracted with dimethylsulfoxyd and water and the resulting eluates mixed together. Neither the bacterial assay nor the mammalian cell system after repeated test series under standardised conditions produced evidence of a toxic or mutagenic effect in the concentration range under study. It is therefore not to be expected that CoCrMo or Ti6Al alloys initiate carcinogenesis in the human organism. (C) 2003 Elsevier Ireland Ltd. All rights reserved."],["dc.identifier.doi","10.1016/S0300-483X(03)00147-1"],["dc.identifier.isi","000185506000002"],["dc.identifier.pmid","12927371"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/45434"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","0300-483X"],["dc.title","In vitro toxicity and mutagenicity of CoCrMo and Ti6Al wear particles"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","e0243306"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","PLoS One"],["dc.bibliographiccitation.volume","15"],["dc.contributor.author","Frosch, Stephan"],["dc.contributor.author","Buchhorn, Gottfried"],["dc.contributor.author","Hawellek, Thelonius"],["dc.contributor.author","Walde, Tim Alexander"],["dc.contributor.author","Lehmann, Wolfgang"],["dc.contributor.author","Hubert, Jan"],["dc.contributor.editor","de Araújo, Gabriel"],["dc.date.accessioned","2021-04-14T08:31:45Z"],["dc.date.available","2021-04-14T08:31:45Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1371/journal.pone.0243306"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/17806"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/83704"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.notes.intern","Merged from goescholar"],["dc.relation.eissn","1932-6203"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Comparison of the double loop knot stitch and Kessler stitch for Achilles tendon repair: A biomechanical cadaver study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","412"],["dc.bibliographiccitation.journal","Acta Biomaterialia"],["dc.bibliographiccitation.lastpage","424"],["dc.bibliographiccitation.volume","31"],["dc.contributor.author","Schunck, Antje"],["dc.contributor.author","Kronz, Andreas"],["dc.contributor.author","Fischer, Cornelius"],["dc.contributor.author","Buchhorn, Gottfried Hans"],["dc.date.accessioned","2018-11-07T10:18:36Z"],["dc.date.available","2018-11-07T10:18:36Z"],["dc.date.issued","2016"],["dc.description.abstract","In a previous failure analysis performed on femoral components of cemented total hip replacements, we determined high volumes of abraded bone cement. Here, we describe the topography of the polished surface of polymethyl methacrylate (PMMA) bone cement containing zirconia radiopacifier, analyzed by scanning electron microscopy and vertical scanning interferometry. Zirconia spikes protruded about 300 nm from the PMMA matrix, with pits of former crystal deposition measuring about 400 nm in depth. We deduced that the characteristically mulberry-shaped agglomerates of zirconia crystals are ground and truncated into flat surfaces and finally torn out of the PMMA matrix. Additionally, evaluation of in vitro PMMA-on-PMMA articulation confirmed that crystal agglomerations of zirconia were exposed to grain pullout, fatigue, and abrasion. In great quantities, micron-sized PMMA wear and zirconia nanoparticles accumulate in the cement-bone interface and capsular tissues, thereby contributing to osteolysis. Dissemination of nanoparticles to distant lymph nodes and organs of storage has been reported. As sufficient information is lacking, foreign body reactions to accumulated nanosized zirconia in places of long-term storage should be investigated. Statement of Significance The production of wear particles of PMMA bone cement in the interface to joint replacement devices, presents a local challenge. The presence of zirconia particles results in frustrated digestion attempts by macrophages, liberation of inflammatory mediators, and necrosis leading to aseptic inflammation and osteolyses. Attempts to minimize wear of articulating joints reduced the attention to the deterioration of cement cuffs. We therefore investigated polished surfaces of retrieved cuffs to demonstrate their morphology and to measure surface roughness. Industrially admixed agglomerates of the radiopacifier are abraded to micron and nano-meter sized particles. The dissemination of zirconia particles in the reticulo-endothelial system to storage organs is a possible burden. Research to replace the actual contrast media by non-particulate material deserves more attention. (C) 2015 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved."],["dc.identifier.doi","10.1016/j.actbio.2015.11.044"],["dc.identifier.isi","000370086100037"],["dc.identifier.pmid","26612414"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/41478"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Sci Ltd"],["dc.relation.issn","1878-7568"],["dc.relation.issn","1742-7061"],["dc.title","Release of zirconia nanoparticles at the metal stem-bone cement interface in implant loosening of total hip replacements"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","106"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Clinical Biomechanics"],["dc.bibliographiccitation.lastpage","111"],["dc.bibliographiccitation.volume","22"],["dc.contributor.author","Klinger, Hans-Michael"],["dc.contributor.author","Steckel, Hanno"],["dc.contributor.author","Spahn, Gunter"],["dc.contributor.author","Buchhorn, Gottfried Hans"],["dc.contributor.author","Baums, Mike Herbert"],["dc.date.accessioned","2018-11-07T11:06:16Z"],["dc.date.available","2018-11-07T11:06:16Z"],["dc.date.issued","2007"],["dc.description.abstract","Background. In recent studies objective evaluations have demonstrated that arthroscopic rotator cuff repairs can have higher failure rates than open repairs. Thus, there is a need for a stronger tissue-holding stitch for arthroscopical repair. The purpose of this study was to compare the biomechanical properties of traditional open transosseous suture technique and modified Mason-Allen stitches versus double-loaded suture anchors and arthroscopic Mason-Allen stitches in rotator cuff repair. Methods. In 20 sheep shoulders the infraspinatus tendons were dissected from their insertion and were randomized to 2 repair groups: (1) repair with transosseous suture and modified Mason-Allen stitches, (2) repair with double loaded bioabsorbable suture anchors and arthroscopic Mason-Allen stitches: Both groups were coupled with braided, nonabsorbable polyester (Ethibond) suture sized USP No. 2. All repairs were cyclically loaded from 10 to 180 N with the use of a materials testing machine. The number of cycles to gap formation of 5 and 10 rum at the repair site and the mode of failure were recorded. Results. The number of cycles to 5-mm gap was mean 634 (SD 106) for group 1 and mean 750 (SD 107) for group 2 (P < 0.026). The corresponding values to 10-mm, gap were mean 1573 (SD 161) for group 1, and mean 1789 (SD 183 cycles) for group 2 (P < 0.012). In group 2 the mode of failure occurred by tissue pull-out, whereas in group 1 the failure occurred by a mixture of suture breakage and pull-out. Conclusions. This time-zero study demonstrates that the combination of bioabsorbable suture anchors and arthroscopic Mason-Allen stitches provides strength superior to that of the modified Mason-Allen transosseous suture technique under isometric cyclic loading conditions. However, additional evaluation is needed to examine the effects on the sustained strength of the repair throughout the healing process. (c) 2006 Elsevier Ltd. All rights reserved."],["dc.identifier.doi","10.1016/j.clinbiomech.2006.07.009"],["dc.identifier.isi","000243680700015"],["dc.identifier.pmid","16996666"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/52266"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Sci Ltd"],["dc.relation.issn","0268-0033"],["dc.title","Biomechanical comparison of double-loaded suture anchors using arthroscopic Mason-Allen Stitches versus traditional transosseous suture technique and modified Mason-Allen stitches for rotator cuff repair"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","263"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Acta Histochemica"],["dc.bibliographiccitation.lastpage","269"],["dc.bibliographiccitation.volume","104"],["dc.contributor.author","Hansen, Thomas C."],["dc.contributor.author","Otto, Markus"],["dc.contributor.author","Buchhorn, Gottfried Hans"],["dc.contributor.author","Scharnweber, Dieter"],["dc.contributor.author","Gaumann, A."],["dc.contributor.author","Delank, K. S."],["dc.contributor.author","Eckardt, A."],["dc.contributor.author","Willert, Hans-Georg"],["dc.contributor.author","Kriegsmann, J."],["dc.contributor.author","Kirkpatrick, C. J."],["dc.date.accessioned","2018-11-07T10:32:39Z"],["dc.date.available","2018-11-07T10:32:39Z"],["dc.date.issued","2002"],["dc.description.abstract","The most important long-term complication in total joint replacements is aseptic osteolysis. Wear particles such as polyethylene (PE) debris are considered to be one of the causes that play a central role. Several studies indicated that PE can be visualised in paraffin-embedded tissue sections not only by polarised light, but also after oil red staining. To determine whether oil red staining enables sensitive detection of PE, we examined staining of mechanically-produced PE particles by oil red. Furthermore, we studied oil red staining of paraffin-embedded tissue specimens of patients with failed uncemented and cemented total knee and hip prostheses. We applied double labelling of sections by immunohistochemistry using the macrophage marker anti-CD68 and oil red staining. We found that oil red stains both isolated PE particles and PE particles in paraffin-embedded tissue sections. Polymethylmethacrylate particles in failed cemented arthroplasties did not stain in paraffin sections. Double labelling showed strong colocalisation of CD68 and PE. We suggest that oil red staining is a sensitive method to detect PE particles. Oil red staining is particularly helpful in these cases which show a characteristic histological feature of aseptic prosthesis loosening without particles being detectable with routine microscopy and polarised light. We also established that immunohistochemical methods can be applied together with the oil red staining method."],["dc.identifier.doi","10.1078/0065-1281-00649"],["dc.identifier.isi","000178430800006"],["dc.identifier.pmid","12389740"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/44397"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Gmbh, Urban & Fischer Verlag"],["dc.relation.issn","0065-1281"],["dc.title","New aspects in the histological examination of polyethylene wear particles in failed total joint replacements"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","551"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Biomaterials"],["dc.bibliographiccitation.lastpage","561"],["dc.bibliographiccitation.volume","21"],["dc.contributor.author","Lohmann, Christoph H."],["dc.contributor.author","Schwartz, Z."],["dc.contributor.author","Koster, G."],["dc.contributor.author","Jahn, U."],["dc.contributor.author","Buchhorn, Gottfried Hans"],["dc.contributor.author","MacDougall, M. J."],["dc.contributor.author","Casasola, D."],["dc.contributor.author","Liu, Y."],["dc.contributor.author","Sylvia, V. L."],["dc.contributor.author","Dean, D. D."],["dc.contributor.author","Boyan, B. D."],["dc.date.accessioned","2018-11-07T08:58:43Z"],["dc.date.available","2018-11-07T08:58:43Z"],["dc.date.issued","2000"],["dc.description.abstract","Wear debris is considered to be one of the main factors responsible for aseptic loosening of orthopaedic endoprostheses. Whereas the response of cells in the monocytic lineage to foreign materials has been extensively studied, little is known about cells at the bone formation site. In the present study, we examined the hypothesis that the response of osteoblasts to wear debris depends on the chemical composition of the particles. We produced particles from commercially pure titanium (cpTi), Ti-6Al-4V (Ti-A), and cobalt-chrome (CoCr) and obtained ultrahigh molecular weight polyethylene (UHMWPE; GUR 4150) particles from a commercial sourer. The equivalent circle diameters of the particles were comparable: 1.0 +/- 0.96 mu m for UHMWPE; 0.84 +/- 0.12 mu m for cpTi; 1.35 +/- 0.09 mu m for Ti-A, and 1.21 +/- 0.16 mu m for CoCr, Confluent primary human osteoblasts and MG63 osteoblast-like cells were incubated in the presence of particles for 24 h. Harvested cultures were examined by transmission electron microscopy to determine if the cells had phagocytosed the particles. Particles were found intracellularly, primarily in the cytosol, in both the primary osteoblasts and MG63 cells. The chemical composition of the particles inside the cells was confirmed by energy-dispersive X-ray analysis. Morphologically, both cell types had extensive ruffled cell membranes, less-developed endoplasmic reticulum, swollen mitochondria, and vacuolic inclusions compared with untreated cells. CpTi, Ti-A, and CoCr particles were also added to cultures of MG63 cells to assess their effect on proliferation (cell number) and differentiation (alkaline phosphatase activity), and PGE(2) production. All three types of particles had effects on the cells. The effect on cell number was dependent on the chemical composition of the particles; Ti-A and CoCr caused a dose-dependent increase, while cpTi particles had a biphasic effect with a maximal increase in cell number observed at the 1 : 10 dilution. Alkaline phosphatase specific activity was also affected and cpTi was more inhibitory than Ti-A or CoCr. PGE(2) production was increased by all particles, but the magnitude of the effect was particle-dependent: CoCr > cpTi > Ti-A. This study demonstrates clearly that human osteoblast-like cells and MG63 cells can phagocytose small UHMWPE, CoCr, Ti-A, and cpTi particles. Phagocytosis of the particles is correlated with changes in morphology, and analysis of MG63 response shows that cell proliferation, differentiation, and prostanoid production are affected. This may have negative effects on bone formation adjacent to an orthopaedic implant and may initiate or contribute to the cellular events that cause aseptic loosening by inhibiting bone formation. The effects on alkaline phosphatase and PGE(2) release are dependent on the chemical composition of the particles, suggesting that both the type and concentration of wear debris at an implant site may be important in determining clinical outcome. (C) 2000 Elsevier Science Ltd. All rights reserved."],["dc.identifier.doi","10.1016/S0142-9612(99)00211-2"],["dc.identifier.isi","000085430300002"],["dc.identifier.pmid","10701456"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/23713"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Sci Ltd"],["dc.relation.issn","0142-9612"],["dc.title","Phagocytosis of wear debris by osteoblasts affects differentiation and local factor production in a manner dependent on particle composition"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Irish Journal of Medical Science (1971 -)"],["dc.bibliographiccitation.volume","184"],["dc.contributor.author","Ernstberger, Thorsten"],["dc.contributor.author","Buchhorn, G."],["dc.contributor.author","Heidrich, Gabert"],["dc.date.accessioned","2018-11-07T10:00:11Z"],["dc.date.available","2018-11-07T10:00:11Z"],["dc.date.issued","2015"],["dc.format.extent","263"],["dc.identifier.doi","10.1007/s11845-015-1266-9"],["dc.identifier.isi","000351840900035"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/37745"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","London"],["dc.relation.issn","1863-4362"],["dc.relation.issn","0021-1265"],["dc.title","Magnetic resonance imaging evaluation of intervertebral test spacers: an experimental comparison of magnesium versus titanium and carbon fiber reinforced polymers as biomaterials (Retraction of vol 179, pg 107, 2010)"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","244"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","ACTA ORTHOPAEDICA BELGICA"],["dc.bibliographiccitation.lastpage","249"],["dc.bibliographiccitation.volume","73"],["dc.contributor.author","Ernstberger, Thorsten"],["dc.contributor.author","Buchhorn, Gottfried"],["dc.contributor.author","Herbertbaums, Mike"],["dc.contributor.author","Heidrich, Gabert"],["dc.date.accessioned","2018-11-07T11:03:18Z"],["dc.date.available","2018-11-07T11:03:18Z"],["dc.date.issued","2007"],["dc.description.abstract","The purpose of this study was to investigate how different materials affect the magnetic resonance imaging (MRI) detectability of interbody test spacers (ITS). We evaluated the post-implantation MRI scans with T1 TSE sequences for three different ITS made of titanium, carbon fibre-reinforced polymers (CFRP) and titanium-coated CFRP, respectively. The main target variables were total artefact volume (TAV) and median artefact area (MAA). Additionally, implant volume (IV)/TAV and cross section (CS)/MAA ratio were determined. The t test and Newman-Keuls test for multiple comparisons were used for statistical analysis. TAV and MAA did not differ significantly between CFRP and titanium-coated CFRP, but were approximately twice as high for the titanium ITS (p < 0.001). MRI detectability was optimum for CFRP and titanium-coated CFRP, but was limited at the implant-bone interface of the titanium ITS. The material's susceptibility and the implant's dimensions affected MRI artefacting. Based on TAV, the volume of titanium surface coating in the ITS studied has no influence on susceptibility in MRI scans with T1 TSE sequences."],["dc.identifier.isi","000254244600016"],["dc.identifier.pmid","17515239"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/51585"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Acta Medica Belgica"],["dc.relation.issn","0001-6462"],["dc.title","In-vitro MRI detectability of interbody test spacers made of carbon fibre-reinforced polymers, titanium and titanium-coated carbon fibre-reinforced polymers"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]