Now showing 1 - 4 of 4
  • 2015Journal Article
    [["dc.bibliographiccitation.artnumber","215"],["dc.bibliographiccitation.journal","Frontiers in Neurology"],["dc.bibliographiccitation.volume","6"],["dc.contributor.author","Primassin, Annika"],["dc.contributor.author","Scholtes, Nina"],["dc.contributor.author","Heim, Stefan"],["dc.contributor.author","Huber, Walter"],["dc.contributor.author","Neuschaefer, Martina"],["dc.contributor.author","Binkofski, Ferdinand"],["dc.contributor.author","Werner, Cornelius J."],["dc.date.accessioned","2018-11-07T09:50:17Z"],["dc.date.available","2018-11-07T09:50:17Z"],["dc.date.issued","2015"],["dc.description.abstract","Despite intensive research on mechanisms of recovery of function after stroke, surprisingly little is known about determinants of concurrent recovery of language and motor functions in single patients. The alternative hypotheses are that the two functions might either \"fight for resources\" or use the same mechanisms in the recovery process. Here, we present follow-up data of four exemplary patients with different base levels of motor and language abilities. We assessed functional scales and performed exact lesion analysis to examine the connection between lesion parameters and recovery potential in each domain. Results confirm that preservation of the corticospinal tracts (CSTs) is a neural predictor for good motor recovery while preservation of the arcuate fasciculus (AF) is important for a good language recovery. However, results further indicate that even patients with large lesions in CST, AF, and superior longitudinal fasciculus, respectively, are able to recover their motor/language abilities during intensive therapy. We further found some indicators of a facilitating interaction between motor and language recovery. Patients with positive improvement of motor skills after therapy also improved in language skills, while the patients with no motor improvements were not able to gain any language recovery."],["dc.identifier.doi","10.3389/fneur.2015.00215"],["dc.identifier.isi","000363935800001"],["dc.identifier.pmid","26500606"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/12619"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/35682"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Frontiers Media Sa"],["dc.relation.issn","1664-2295"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Determinants of concurrent motor and language recovery during intensive therapy in chronic stroke patients: four single-case studies"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
    Details DOI PMID PMC WOS
  • 2015Journal Article
    [["dc.bibliographiccitation.artnumber","374"],["dc.bibliographiccitation.journal","Frontiers in Cellular Neuroscience"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Ambrus, Geza Gergely"],["dc.contributor.author","Pisoni, Alberto"],["dc.contributor.author","Primassin, Annika"],["dc.contributor.author","Turi, Zsolt"],["dc.contributor.author","Paulus, Walter J."],["dc.contributor.author","Antal, Andrea"],["dc.date.accessioned","2018-11-07T09:51:30Z"],["dc.date.available","2018-11-07T09:51:30Z"],["dc.date.issued","2015"],["dc.description.abstract","High frequency oscillations in the hippocampal structures recorded during sleep have been proved to be essential for long-term episodic memory consolidation in both animals and in humans. The aim of this study was to test if transcranial Alternating Current Stimulation (tACS) of the dorsolateral prefrontal cortex (DLPFC) in the hippocampal ripple range, applied bi-frontally during encoding, could modulate declarative memory performance, measured immediately after encoding, and after a night's sleep. An associative word-pair learning test was used. During an evening encoding phase, participants received 1 mA 140 Hz tACS or sham stimulation over both DLPFCs for 10 min while being presented twice with a list of word-pairs. Cued recall performance was investigated 10 min after training and the morning following the training session. Forgetting from evening to morning was observed in the sham condition, but not in the 140 Hz stimulation condition. 140 Hz tACS during encoding may have an effect on the consolidation of declarative material."],["dc.description.sponsorship","Open-Access Publikationsfonds 2015"],["dc.identifier.doi","10.3389/fncel.2015.00374"],["dc.identifier.isi","000361694300001"],["dc.identifier.pmid","26441544"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/12165"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/35932"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Frontiers Media Sa"],["dc.relation.issn","1662-5102"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Bi-frontal transcranial alternating current stimulation in the ripple range reduced overnight forgetting"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
    Details DOI PMID PMC WOS
  • 2021Journal Article
    [["dc.bibliographiccitation.artnumber","S1053811921010089"],["dc.bibliographiccitation.firstpage","118736"],["dc.bibliographiccitation.journal","NeuroImage"],["dc.bibliographiccitation.volume","245"],["dc.contributor.author","Korzeczek, Alexandra"],["dc.contributor.author","Primaßin, Annika"],["dc.contributor.author","Wolff von Gudenberg, Alexander"],["dc.contributor.author","Dechent, Peter"],["dc.contributor.author","Paulus, Walter"],["dc.contributor.author","Sommer, Martin"],["dc.contributor.author","Neef, Nicole E."],["dc.date.accessioned","2021-12-01T09:23:04Z"],["dc.date.available","2021-12-01T09:23:04Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.1016/j.neuroimage.2021.118736"],["dc.identifier.pii","S1053811921010089"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/94553"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-478"],["dc.relation.issn","1053-8119"],["dc.title","Fluency shaping increases integration of the command-to-execution and the auditory-to-motor pathways in persistent developmental stuttering"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
    Details DOI
  • 2022Journal Article Research Paper
    [["dc.bibliographiccitation.journal","Human Brain Mapping"],["dc.contributor.author","Neef, Nicole E."],["dc.contributor.author","Korzeczek, Alexandra"],["dc.contributor.author","Primaßin, Annika"],["dc.contributor.author","Wolff von Gudenberg, Alexander"],["dc.contributor.author","Dechent, Peter"],["dc.contributor.author","Riedel, Christian Heiner"],["dc.contributor.author","Paulus, Walter"],["dc.contributor.author","Sommer, Martin"],["dc.date.accessioned","2022-05-02T08:02:09Z"],["dc.date.available","2022-05-02T08:02:09Z"],["dc.date.issued","2022"],["dc.description.abstract","Persistent stuttering is a prevalent neurodevelopmental speech disorder, which presents with involuntary speech blocks, sound and syllable repetitions, and sound prolongations. Affected individuals often struggle with negative feelings, elevated anxiety, and low self-esteem. Neuroimaging studies frequently link persistent stuttering with cortical alterations and dysfunctional cortico-basal ganglia-thalamocortical loops; dMRI data also point toward connectivity changes of the superior longitudinal fasciculus (SLF) and the frontal aslant tract (FAT). Both tracts are involved in speech and language functions, and the FAT also supports inhibitory control and conflict monitoring. Whether the two tracts are involved in therapy-associated improvements and how they relate to therapeutic outcomes is currently unknown. Here, we analyzed dMRI data of 22 patients who participated in a fluency-shaping program, 18 patients not participating in therapy, and 27 fluent control participants, measured 1 year apart. We used diffusion tractography to segment the SLF and FAT bilaterally and to quantify their microstructural properties before and after a fluency-shaping program. Participants learned to speak with soft articulation, pitch, and voicing during a 2-week on-site boot camp and computer-assisted biofeedback-based daily training for 1 year. Therapy had no impact on the microstructural properties of the two tracts. Yet, after therapy, stuttering severity correlated positively with left SLF fractional anisotropy, whereas relief from the social–emotional burden to stutter correlated negatively with right FAT fractional anisotropy. Thus, posttreatment, speech motor performance relates to the left dorsal stream, while the experience of the adverse impact of stuttering relates to the structure recently associated with conflict monitoring and action inhibition."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2022"],["dc.identifier.doi","10.1002/hbm.25853"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/107245"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-561"],["dc.relation.eissn","1097-0193"],["dc.relation.issn","1065-9471"],["dc.rights","CC BY-NC-ND 4.0"],["dc.rights.uri","http://creativecommons.org/licenses/by-nc-nd/4.0/"],["dc.title","White matter tract strength correlates with therapy outcome in persistent developmental stuttering"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]
    Details DOI