Shirota, Yuichiro

[["dc.bibliographiccitation.firstpage","1244"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Brain Stimulation"],["dc.bibliographiccitation.lastpage","1252"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Halawa, I."],["dc.contributor.author","Shirota, Y."],["dc.contributor.author","Neef, A."],["dc.contributor.author","Sommer, M."],["dc.contributor.author","Paulus, W."],["dc.date.accessioned","2020-12-10T14:22:48Z"],["dc.date.available","2020-12-10T14:22:48Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1016/j.brs.2019.04.012"],["dc.identifier.issn","1935-861X"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/71740"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Neuronal tuning: Selective targeting of neuronal populations via manipulation of pulse width and directionality"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","109"],["dc.bibliographiccitation.journal","Neuroscience Letters"],["dc.bibliographiccitation.lastpage","113"],["dc.bibliographiccitation.volume","650"],["dc.contributor.author","Shirota, Yuichiro"],["dc.contributor.author","Dhaka, Suman"],["dc.contributor.author","Paulus, Walter J."],["dc.contributor.author","Sommer, Martin"],["dc.date.accessioned","2018-11-07T10:23:41Z"],["dc.date.available","2018-11-07T10:23:41Z"],["dc.date.issued","2017"],["dc.description.abstract","Background: Transcranial magnetic stimulation (TMS) with different current directions can activate different sets of neurons. Current direction can also affect the results of repetitive TMS. Objective: : To test the influence of uni-directional intermittent theta burst stimulation (iTBS) using different current directions, namely posteroanterior (PA) and anteroposterior (AP), on motor behaviour. Methods: In a cross-over design, PA- and AP-iTBS was applied over the left primary motor cortex in 19 healthy, right-handed volunteers. Performance of a finger-tapping task was recorded before and 0,10,20, and 30 min after the iTBS. The task was conducted with the right and left hands separately at each time point. As a control, AP-iTBS with reduced intensity was applied to 14 participants in a separate session (AP(weak) condition). Results: The finger-tapping count with the left hand was decreased after PA-iTBS. Neither AP-nor AP(weak)- iTBS altered the performance. Conclusions: Current direction had a significant impact on the after-effects of iTBS. (C) 2017 Elsevier B.V. All rights reserved."],["dc.description.sponsorship","Alexander von Humboldt Foundation; DAAD-DFG fellowship Program"],["dc.identifier.doi","10.1016/j.neulet.2017.04.032"],["dc.identifier.isi","000402359100018"],["dc.identifier.pmid","28435045"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/42511"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Elsevier Ireland Ltd"],["dc.relation.issn","1872-7972"],["dc.relation.issn","0304-3940"],["dc.title","Current direction-dependent modulation of human hand motor function by intermittent theta burst stimulation (iTBS)"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","755"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Brain Stimulation"],["dc.bibliographiccitation.lastpage","761"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Shirota, Yuichiro"],["dc.contributor.author","Sommer, Martin"],["dc.contributor.author","Paulus, Walter J."],["dc.date.accessioned","2018-11-07T10:09:43Z"],["dc.date.available","2018-11-07T10:09:43Z"],["dc.date.issued","2016"],["dc.description.abstract","Background: Paired-pulse protocols have played a pivotal role in neuroscience research using transcranial magnetic stimulation (TMS). Stimulus parameters have been optimized over the years. More recently, pulse width (PW) has been introduced to this field as a new parameter, which may further fine-tune paired-pulse protocols. The relationship between the PW and effectiveness of a stimulus is known as the \"strength-duration relationship\". Objective: To test the \"strength-duration relationship\", so as to improve paired-pulse TMS protocols, and to apply the results to develop new repetitive TMS (rTMS) methods. Methods: Four protocols were investigated separately: short-interval intracortical inhibition (SICI), intracortical facilitation (ICF), short-interval intracortical facilitation (SICF) and long-interval intracortical inhibition (LICI). First, various stimulus parameters were tested to identify those yielding the largest facilitation or inhibition of the motor evoked potential (MEP) in each participant. Using these parameters, paired-pulse stimulations were repeated every five seconds for 30 minutes (repetitive paired-pulse stimulation, rPPS). The after-effects of rPPS were measured using MEP amplitude as an index of motor-cortical excitability. Results: Altogether, the effect of changing PW was similar to that of changing the stimulus intensity in the conventional settings. The best parameters were different for each participant. When these parameters were used, rPPS based on either SICF or ICF induced an increase in MEP amplitude. Conclusions: PW was introduced as a new parameter in paired-pulse TMS. Modulation of PW influenced the results of paired-pulse protocols. rPPS using facilitatory protocols can be a good candidate to induce enhancement of motor-cortical excitability. (C) 2016 Elsevier Inc. All rights reserved."],["dc.identifier.doi","10.1016/j.brs.2016.04.019"],["dc.identifier.isi","000382499100013"],["dc.identifier.pmid","27234142"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/39705"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.relation.issn","1876-4754"],["dc.relation.issn","1935-861X"],["dc.title","Strength-Duration Relationship in Paired-pulse Transcranial Magnetic Stimulation (TMS) and Its Implications for Repetitive TMS"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Frontiers in Behavioral Neuroscience"],["dc.bibliographiccitation.volume","11"],["dc.contributor.author","Shirota, Yuichiro"],["dc.contributor.author","Terney, Daniella"],["dc.contributor.author","Antal, Andrea"],["dc.contributor.author","Paulus, Walter"],["dc.date.accessioned","2020-12-10T18:44:30Z"],["dc.date.available","2020-12-10T18:44:30Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.3389/fnbeh.2017.00169"],["dc.identifier.eissn","1662-5153"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/17008"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78479"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Influence of Concurrent Finger Movements on Transcranial Direct Current Stimulation (tDCS)-Induced Aftereffects"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","618"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Brain Stimulation"],["dc.bibliographiccitation.lastpage","619"],["dc.bibliographiccitation.volume","7"],["dc.contributor.author","Shirota, Yuichiro"],["dc.contributor.author","Hewitt, Manuel"],["dc.contributor.author","Paulus, Walter J."],["dc.date.accessioned","2018-11-07T09:38:03Z"],["dc.date.available","2018-11-07T09:38:03Z"],["dc.date.issued","2014"],["dc.identifier.doi","10.1016/j.brs.2014.01.061"],["dc.identifier.isi","000339984300018"],["dc.identifier.pmid","24685516"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/32979"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.relation.issn","1876-4754"],["dc.relation.issn","1935-861X"],["dc.title","Neuroscientists Do Not Use Non-invasive Brain Stimulation on Themselves for Neural Enhancement"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.subtype","letter_note"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","358"],["dc.bibliographiccitation.firstpage","1"],["dc.bibliographiccitation.journal","Frontiers in Neuroscience"],["dc.bibliographiccitation.lastpage","12"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Halawa, Islam"],["dc.contributor.author","Goldental, Amir"],["dc.contributor.author","Shirota, Yuichiro"],["dc.contributor.author","Kanter, Ido"],["dc.contributor.author","Paulus, Walter"],["dc.date.accessioned","2018-10-10T09:39:17Z"],["dc.date.available","2018-10-10T09:39:17Z"],["dc.date.issued","2018"],["dc.description.abstract","Introduction: rTMS has been proven effective in the treatment of neuropsychiatric conditions, with class A (definite efficacy) evidence for treatment of depression and pain (Lefaucheur et al., 2014). The efficacy in stimulation protocols is, however, quite heterogeneous. Saturation of neuronal firing by HFrTMS without allowing time for recovery may lead to neuronal response failures (NRFs) that compromise the efficacy of stimulation with higher frequencies. Objectives: To examine the efficacy of different rTMS temporal stimulation patterns focusing on a possible upper stimulation limit related to response failures. Protocol patterns were derived from published clinical studies on therapeutic rTMS for depression and pain. They were compared with conduction failures in cell cultures. Methodology: From 57 papers using protocols rated class A for depression and pain (Lefaucheur et al., 2014) we extracted Inter-train interval (ITI), average frequency, total duration and total number of pulses and plotted them against the percent improvement on the outcome scale. Specifically, we compared 10 Hz trains with ITIs of 8 s (protocol A) and 26 s (protocol B) in vitro on cultured cortical neurons. Results: In the in vitro experiments, protocol A with 8-s ITIs resulted in more frequent response failures, while practically no response failures occurred with protocol B (26-s intervals). The HFrTMS protocol analysis exhibited no significant effect of ITIs on protocol efficiency. Discussion: In the neuronal culture, longer ITIs appeared to allow the neuronal response to recover. In the available human dataset on both depression and chronic pain, data concerning shorter ITIs is does not allow a significant conclusion. Significance: NRF may interfere with the efficacy of rTMS stimulation protocols when the average stimulation frequency is too high, proposing ITIs as a variable in rTMS protocol efficacy. Clinical trials are necessary to examine effect of shorter ITIs on the clinical outcome in a controlled setting."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2018"],["dc.identifier.doi","10.3389/fnins.2018.00358"],["dc.identifier.pmid","29910706"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/15266"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/15935"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","final"],["dc.publisher","Frontiers Media S.A."],["dc.relation.eissn","1662-453X"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Less Might Be More"],["dc.title.subtitle","Conduction Failure as a Factor Possibly Limiting the Efficacy of Higher Frequencies in rTMS Protocols"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1096"],["dc.bibliographiccitation.journal","Journal of the Neurological Sciences"],["dc.bibliographiccitation.volume","381"],["dc.contributor.author","Shirota, Y."],["dc.contributor.author","Sommer, M."],["dc.contributor.author","Paulus, W."],["dc.date.accessioned","2020-12-10T14:25:15Z"],["dc.date.available","2020-12-10T14:25:15Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1016/j.jns.2017.08.3093"],["dc.identifier.issn","0022-510X"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/72499"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Making use of paired-pulse transcranial magnetic stimulation (TMS) for plasticity induction by repetitive TMS"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]