Walliser, Karoline

[["dc.bibliographiccitation.firstpage","50"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Der Nervenarzt"],["dc.bibliographiccitation.lastpage","56"],["dc.bibliographiccitation.volume","92"],["dc.contributor.author","Zilles-Wegner, David"],["dc.contributor.author","Trost, Sarah"],["dc.contributor.author","Walliser, Karoline"],["dc.contributor.author","Saager, Leif"],["dc.contributor.author","Horn, Sebastian"],["dc.contributor.author","Ernst, Mareike"],["dc.date.accessioned","2021-04-14T08:24:49Z"],["dc.date.available","2021-04-14T08:24:49Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1007/s00115-020-00960-7"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/81434"],["dc.language.iso","de"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1433-0407"],["dc.relation.issn","0028-2804"],["dc.title","Elektrokonvulsionstherapie in der Schwangerschaft: Fallbericht und interdisziplinäre Behandlungsvorschläge"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","122"],["dc.bibliographiccitation.journal","Scandinavian Journal of Trauma Resuscitation and Emergency Medicine"],["dc.bibliographiccitation.volume","24"],["dc.contributor.author","Kunze-Szikszay, Nils"],["dc.contributor.author","Krack, Lennart A."],["dc.contributor.author","Wildenauer, Pauline"],["dc.contributor.author","Wand, Saskia"],["dc.contributor.author","Heyne, Tim"],["dc.contributor.author","Walliser, Karoline"],["dc.contributor.author","Spering, Christopher"],["dc.contributor.author","Bauer, Martin"],["dc.contributor.author","Quintel, Michael"],["dc.contributor.author","Roessler, Markus"],["dc.date.accessioned","2018-11-07T10:07:07Z"],["dc.date.available","2018-11-07T10:07:07Z"],["dc.date.issued","2016"],["dc.description.abstract","Background: Hyperfibrinolysis (HF) is a major contributor to coagulopathy and mortality in trauma patients. This study investigated (i) the rate of HF during the pre-hospital management of patients with multiple injuries and (ii) the effects of pre-hospital tranexamic acid (TxA) administration on the coagulation system. Methods: From 27 trauma patients with pre-hospital an estimated injury severity score (ISS) >= 16 points blood was obtained at the scene and on admission to the emergency department (ED). All patients received 1 g of TxA after the first blood sample was taken. Rotational thrombelastometry (ROTEM) was performed for both blood samples, and the results were compared. HF was defined as a maximum lysis (ML) >15 % in EXTEM. Results: The median (min-max) ISS was 17 points (4-50 points). Four patients (15 %) had HF diagnosed via ROTEM at the scene, and 2 patients (7.5 %) had HF diagnosed via ROTEM on admission to the ED. The median ML before TxA administration was 11 % (3-99 %) vs. 10 % after TxA administration (4-18 %; p > 0.05). TxA was administered 37 min (10-85 min) before ED arrival. The ROTEM results before and after TxA administration did not significantly differ. No adverse drug reactions were observed after TxA administration. Discussion: HF can be present in severely injured patients during pre-hospital care. Antifibrinolytic therapy administered at the scene is a significant time saver. Even in milder trauma fibrinogen can be decreased to critically low levels. Early administration of TxA cannot reverse or entirely stop this decrease. Conclusions: The pre-hospital use of TxA should be considered for severely injured patients to prevent the worsening of trauma-induced coagulopathy and unnecessarily high fibrinogen consumption."],["dc.identifier.doi","10.1186/s13049-016-0314-4"],["dc.identifier.isi","000384950400003"],["dc.identifier.pmid","27724970"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/13894"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/39223"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Biomed Central Ltd"],["dc.relation.issn","1757-7241"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","The pre-hospital administration of tranexamic acid to patients with multiple injuries and its effects on rotational thrombelastometry: a prospective observational study in pre-hospital emergency medicine"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Laryngo-Rhino-Otologie"],["dc.contributor.author","Bevis, Nicholas"],["dc.contributor.author","Walliser, Karoline"],["dc.contributor.author","Rödel, Ralph"],["dc.contributor.author","Beutner, Dirk"],["dc.contributor.author","Dombrowski, Tobias"],["dc.date.accessioned","2021-08-12T07:45:07Z"],["dc.date.available","2021-08-12T07:45:07Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.1055/a-1509-8965"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/88374"],["dc.language.iso","de"],["dc.notes.intern","DOI Import GROB-448"],["dc.relation.eissn","1438-8685"],["dc.relation.issn","0935-8943"],["dc.title","Indikation, Durchführung und Analyse der Drug-induced sleep endoscopy (DISE)"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","284"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Laboratory Animals"],["dc.bibliographiccitation.lastpage","291"],["dc.bibliographiccitation.volume","51"],["dc.contributor.author","Reupke, Verena"],["dc.contributor.author","Walliser, Karoline"],["dc.contributor.author","Perl, Thorsten"],["dc.contributor.author","Kimmina, Sarah"],["dc.contributor.author","Schraepler, Anke"],["dc.contributor.author","Quintel, Michael"],["dc.contributor.author","Kunze-Szikszay, Nils"],["dc.date.accessioned","2018-11-07T10:23:32Z"],["dc.date.available","2018-11-07T10:23:32Z"],["dc.date.issued","2017"],["dc.description.abstract","The aim of this study was to evaluate a total intravenous anaesthesia (TIVA) protocol using propofol and sufentanil without neuromuscular blocking agents (NBAs) for a non-recovery lung pathology study in rabbits including 10 h of pressure-controlled ventilation. TIVA was started with 20 mg/kg/h propofol and 0.5 mg/kg/h sufentanil. The depth of anaesthesia was assessed by reflex testing and monitoring of spontaneous movements or respiratory efforts. Vital parameters were monitored to assess the effects of the TIVA protocol. The infusion rates were increased whenever reflex testing indicated inadequate depth of anaesthesia, and were reduced when vital parameters indicated unnecessarily deep levels. Median infusion rates of 35 mg/kg/h propofol and 2.0 mg/kg/h sufentanil were needed to ensure an adequate depth of anaesthesia. This protocol suppressed spontaneous movements, breathing and palpebral reflexes, but was unable to suppress corneal and pedal withdrawal reflexes. Since significant drops in arterial blood pressure (ABP) were observed and the animals were not exposed to painful procedures, positive corneal and pedal withdrawal reflexes were tolerated. In conclusion, propofol and sufentanil is a suitable combination for long-term anaesthesia in non-recovery lung pathology models in rabbits without painful procedures. ABP must be monitored carefully because of the circulatory side-effects, but it is an inappropriate surrogate marker for depth of anaesthesia. Due to the lack of neuromuscular blockade this TIVA protocol allows the adjustment of infusion rates based on reflex testing. The resulting decreased risk of unnoticed awareness is a decisive refinement in anaesthesia for similar studies including long-term mechanical ventilation in rabbits."],["dc.description.sponsorship","Faculty of Medicine of the University of Gottingen"],["dc.identifier.doi","10.1177/0023677216660337"],["dc.identifier.isi","000401251400005"],["dc.identifier.pmid","27413175"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/42476"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Sage Publications Inc"],["dc.relation.issn","1758-1117"],["dc.relation.issn","0023-6772"],["dc.title","Total intravenous anaesthesia using propofol and sufentanil allows controlled long-term ventilation in rabbits without neuromuscular blocking agents"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","e234"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Critical Care Medicine"],["dc.bibliographiccitation.lastpage","e240"],["dc.bibliographiccitation.volume","47"],["dc.contributor.author","Kunze-Szikszay, Nils"],["dc.contributor.author","Walliser, Karoline"],["dc.contributor.author","Luther, Jakob"],["dc.contributor.author","Cambiaghi, Barbara"],["dc.contributor.author","Reupke, Verena"],["dc.contributor.author","Dullin, Christian"],["dc.contributor.author","Vautz, Wolfgang"],["dc.contributor.author","Bremmer, Felix"],["dc.contributor.author","Telgheder, Ursula"],["dc.contributor.author","Zscheppank, Cornelia"],["dc.contributor.author","Quintel, Michael"],["dc.contributor.author","Perl, Thorsten"],["dc.date.accessioned","2020-12-10T18:19:50Z"],["dc.date.available","2020-12-10T18:19:50Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1097/CCM.0000000000003573"],["dc.identifier.issn","0090-3493"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/75397"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Detecting Early Markers of Ventilator-Associated Pneumonia by Analysis of Exhaled Gas"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]