Schmelting, Barthel

[["dc.bibliographiccitation.firstpage","S348"],["dc.bibliographiccitation.journal","European Neuropsychopharmacology"],["dc.bibliographiccitation.volume","18"],["dc.contributor.author","Fuchs, E."],["dc.contributor.author","Corbach-Söhle, S."],["dc.contributor.author","Schmelting, B."],["dc.contributor.author","Mocaer, E."],["dc.contributor.author","Millan, M.J."],["dc.contributor.author","Gabriel-Gracia, C."],["dc.date.accessioned","2022-10-06T13:33:57Z"],["dc.date.available","2022-10-06T13:33:57Z"],["dc.date.issued","2008"],["dc.identifier.doi","10.1016/S0924-977X(08)70488-7"],["dc.identifier.pii","S0924977X08704887"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/115783"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.issn","0924-977X"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","P.2.d.006 Effects of agomelatine and S32006, a selective 5-HT2C receptor antagonist, in chronically-stressed tree shrews"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","369"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","MULTIPLE SCLEROSIS"],["dc.bibliographiccitation.lastpage","374"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Merkler, Doron"],["dc.contributor.author","Schmelting, Barthel"],["dc.contributor.author","Czeh, Boldizsar"],["dc.contributor.author","Fuchs, E."],["dc.contributor.author","Stadelmann, Christine"],["dc.contributor.author","Brueck, Wolfgang"],["dc.date.accessioned","2018-11-07T09:30:14Z"],["dc.date.available","2018-11-07T09:30:14Z"],["dc.date.issued","2006"],["dc.description.abstract","Pathomorphological studies described pathological heterogeneity in patients with multiple sclerosis (MS). Different effector mechanisms might therefore be responsible for lesion formation in MS. The present report shows that myelin oligodendrocyte glycoprotein (MOG)-induced experimental autoimmune encephalomyelitis (EAE) in common marmoset monkeys reflects one specific lesional subtype of MS, namely MS pattern 11 lesions with antibody/complement-mediated damage. MOG-induced EAE in marmoset monkeys will, therefore, provide an ideal model for therapeutic approaches directed against B-cell/antibody/complement in MS."],["dc.identifier.doi","10.1191/1352458506ms1290oa"],["dc.identifier.isi","000239431200002"],["dc.identifier.pmid","16900750"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/31257"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Sage Publications Ltd"],["dc.relation.issn","1352-4585"],["dc.title","Myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis in the common marmoset reflects the immunopathology of pattern II multiple sclerosis lesions"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2527"],["dc.bibliographiccitation.issue","1600"],["dc.bibliographiccitation.journal","Proceedings of the Royal Society B: Biological Sciences"],["dc.bibliographiccitation.lastpage","2533"],["dc.bibliographiccitation.volume","273"],["dc.contributor.author","Lutermann, Heike"],["dc.contributor.author","Schmelting, Barthel"],["dc.contributor.author","Radespiel, Ute"],["dc.contributor.author","Ehresmann, Petra"],["dc.contributor.author","Zimmermann, Elke"],["dc.date.accessioned","2022-10-06T13:35:35Z"],["dc.date.available","2022-10-06T13:35:35Z"],["dc.date.issued","2006"],["dc.description.abstract","It is widely accepted that natal philopatry is a prerequisite for the evolution of sociality. The life-history hypothesis maintains that longevity of adults results in extended territory tenure and thus limits breeding vacancies for offspring, which makes natal philopatry more likely. Here, we tested the importance of longevity for natal philopatry in females of a basal primate, the grey mouse lemur (\n Microcebus murinus\n ). This species is regarded as being solitary due to its foraging habits but while males disperse, female offspring in this species forgo dispersal and form long-term sleeping groups with their mothers. We tested whether high adult survival could be a cause for natal philopatry of female offspring. In addition, we assessed costs and benefits associated with space sharing between mothers and daughters and whether mothers actively increase survival of daughters by beqeauthal of territories, information transfer about resources or thermoregulation. Contrary to our predictions, adult females had low-survival rates. Space sharing appeared to improve survival of both, mothers and daughters. This could be a result of information transfer about sleeping sites and thermoregulatory benefits. Our results cast doubt on the idea that longevity predisposes species for social traits and provide support for benefits of philopatry."],["dc.identifier.doi","10.1098/rspb.2006.3603"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/116133"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.eissn","1471-2954"],["dc.relation.issn","0962-8452"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","The role of survival for the evolution of female philopatry in a solitary forager, the grey mouse lemur (\n Microcebus murinus\n )"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","67"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Neuropsychopharmacology"],["dc.bibliographiccitation.lastpage","79"],["dc.bibliographiccitation.volume","30"],["dc.contributor.author","Czeh, Boldizsár"],["dc.contributor.author","Simon, Mária"],["dc.contributor.author","van der Hart, Marieke GC"],["dc.contributor.author","Schmelting, Barthel"],["dc.contributor.author","Hesselink, Mayke B"],["dc.contributor.author","Fuchs, Eberhard"],["dc.date.accessioned","2022-10-06T13:34:21Z"],["dc.date.available","2022-10-06T13:34:21Z"],["dc.date.issued","2004"],["dc.identifier.doi","10.1038/sj.npp.1300581"],["dc.identifier.pii","BF1300581"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/115888"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.eissn","1740-634X"],["dc.relation.issn","0893-133X"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","Chronic Stress Decreases the Number of Parvalbumin-Immunoreactive Interneurons in the Hippocampus: Prevention by Treatment with a Substance P Receptor (NK1) Antagonist"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","S17"],["dc.bibliographiccitation.journal","International Clinical Psychopharmacology"],["dc.bibliographiccitation.lastpage","S20"],["dc.bibliographiccitation.volume","21"],["dc.contributor.author","Fuchs, E."],["dc.contributor.author","Simon, Maria"],["dc.contributor.author","Schmelting, Barthel"],["dc.date.accessioned","2018-11-07T10:22:38Z"],["dc.date.available","2018-11-07T10:22:38Z"],["dc.date.issued","2006"],["dc.description.abstract","The limitations of current antidepressant medications merit the exploration of alternative agents with novel antidepressant mechanisms of action. The established clinical finding that desynchronization of internal rhythms plays an important role in the pathophysiology of depressive disorders has stimulated the idea that resetting normal circadian rhythms may have antidepressant potential. Recent experiments using the novel melatonin receptor agonist and serotonin 2 (5-HT2c) receptor antagonist agomelatine (S20098; N[2-(7-methoxy-1-naphthyl)ethyl]acetamide) revealed a notable chronobiotic activity and clear antidepressant-like effects in a variety of preclinical models. Binding studies performed in vitro proved that agomelatine is a high-affinity agonist at both the melatonin MT1 and MT2 receptor types. In addition, these studies revealed that agomelatine, in contrast to melatonin, blocks 5-HT2c receptors with significant affinity. Antagonism of 5-HT2c receptors is reported for various established antidepressant compounds. The antidepressant properties of agomelatine are thus based on its melatonergic actions and 5-HT2c receptor antagonism."],["dc.identifier.doi","10.1097/01.yic.0000199456.39552.c7"],["dc.identifier.isi","000235686900003"],["dc.identifier.pmid","16436935"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/42313"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Lippincott Williams & Wilkins"],["dc.publisher.place","Philadelphia"],["dc.relation.conference","Satellite Symposium on Acting on Melatonergic Receptors held at the 18th ECNP Congress"],["dc.relation.eventlocation","Amsterdam, NETHERLANDS"],["dc.relation.issn","0268-1315"],["dc.title","Pharmacology of a new antidepressant: benefit of the implication of the melatonergic system"],["dc.type","conference_paper"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","MULTIPLE SCLEROSIS"],["dc.bibliographiccitation.volume","11"],["dc.contributor.author","Merkler, Doron"],["dc.contributor.author","Schmelting, Barthel"],["dc.contributor.author","Czeh, Boldizsar"],["dc.contributor.author","Fuchs, E."],["dc.contributor.author","Bruck, Wolfgang W."],["dc.contributor.author","Stadelmann, Christine"],["dc.date.accessioned","2018-11-07T10:56:29Z"],["dc.date.available","2018-11-07T10:56:29Z"],["dc.date.issued","2005"],["dc.format.extent","S44"],["dc.identifier.isi","000232249900160"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/50021"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Hodder Arnold, Hodder Headline Plc"],["dc.publisher.place","London"],["dc.relation.conference","21st Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis/10th Annual Meeting of Rehabilitation in MS"],["dc.relation.eventlocation","Thessaloniki, GREECE"],["dc.relation.issn","1352-4585"],["dc.title","MOG-induced EAE in the common marmoset shows extensive cortical demyelination"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","S364"],["dc.bibliographiccitation.journal","European Neuropsychopharmacology"],["dc.bibliographiccitation.lastpage","S365"],["dc.bibliographiccitation.volume","17"],["dc.contributor.author","Corbach, S."],["dc.contributor.author","Schmelting, B."],["dc.contributor.author","Fuchs, E."],["dc.contributor.author","Mocaer, E."],["dc.date.accessioned","2022-10-06T13:33:56Z"],["dc.date.available","2022-10-06T13:33:56Z"],["dc.date.issued","2007"],["dc.identifier.doi","10.1016/S0924-977X(07)70534-5"],["dc.identifier.pii","S0924977X07705345"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/115780"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.issn","0924-977X"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","P.2.d.005 Comparison of agomelatine and melatonin for effects in chronically stressed tree shrews, an animal model of depression"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","3707"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Investigative Opthalmology & Visual Science"],["dc.bibliographiccitation.lastpage","3714"],["dc.bibliographiccitation.volume","49"],["dc.contributor.author","Diem, Ricarda"],["dc.contributor.author","Demmer, Iris"],["dc.contributor.author","Boretius, Susann"],["dc.contributor.author","Merkler, Doron"],["dc.contributor.author","Schmelting, Barthel"],["dc.contributor.author","Williams, Sarah K."],["dc.contributor.author","Sättler, Muriel B."],["dc.contributor.author","Bähr, Mathias"],["dc.contributor.author","Michaelis, Thomas"],["dc.contributor.author","Frahm, Jens"],["dc.contributor.author","Brück, Wolfgang"],["dc.contributor.author","Fuchs, Eberhard"],["dc.date.accessioned","2017-09-07T11:45:29Z"],["dc.date.available","2017-09-07T11:45:29Z"],["dc.date.issued","2008"],["dc.description.abstract","purpose. To assess the use of visual evoked potentials (VEPs) for the in vivo detection of impaired visual function in a marmoset model of multiple sclerosis. The sensitivity of the VEP recordings was determined by comparison with magnetic resonance imaging (MRI) and histopathology.methods. Baseline VEPs were recorded in six healthy marmoset monkeys in response to light-flash stimulation. Experimental autoimmune encephalomyelitis (EAE) was induced in four of the six monkeys. Clinical scores were assessed daily, and VEPs were recorded every second week. In vivo MRI and subsequent histopathology of the brains and optic nerves were performed at the end of the study.results. After induction of EAE, all four marmosets exhibited clinical signs between day 26 and 38 after immunization. VEPs were normal during the induction phase of the disease, but deteriorated in amplitude with the occurrence of clinical symptoms in all animals. MRI revealed bilateral optic neuritis and signal alterations in the optic tracts and occipital subcortical white matter in two of the animals. In the remaining two animals, MRI detected signal alterations in the occipital subcortical white matter. Histopathologic results were concordant with the MRI findings.conclusions. VEPs are an easily accessible noninvasive tool for measuring visual function and diagnosing impairment of the visual pathway in a marmoset EAE model."],["dc.identifier.doi","10.1167/iovs.08-1896"],["dc.identifier.gro","3150371"],["dc.identifier.pmid","18450589"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/7128"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.issn","1552-5783"],["dc.title","Autoimmune Optic Neuritis in the Common Marmoset Monkey: Comparison of Visual Evoked Potentials with MRI and Histopathology"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Acta Neuropathologica"],["dc.bibliographiccitation.volume","110"],["dc.contributor.author","Merkler, Doron"],["dc.contributor.author","Schmelting, Barthel"],["dc.contributor.author","Czeh, Boldizsar"],["dc.contributor.author","Fuchs, E."],["dc.contributor.author","Bruck, Wolfgang W."],["dc.contributor.author","Stadelmann, Christine"],["dc.date.accessioned","2018-11-07T10:55:50Z"],["dc.date.available","2018-11-07T10:55:50Z"],["dc.date.issued","2005"],["dc.format.extent","333"],["dc.identifier.isi","000232160500064"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/49876"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","New york"],["dc.relation.conference","50th Annual Meeting of the German-Society-of-Neuropathology-and-Neuroanatomy"],["dc.relation.eventlocation","Graz, AUSTRIA"],["dc.relation.issn","0001-6322"],["dc.title","Extensive cortical demyelination in MOG-induced EAE in the common marmoset"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","95"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Mammalian Biology"],["dc.bibliographiccitation.lastpage","105"],["dc.bibliographiccitation.volume","75"],["dc.contributor.author","Ferner, Kirsten"],["dc.contributor.author","Zeller, Ulrich"],["dc.contributor.author","Schmelting, Barthel"],["dc.contributor.author","Fuchs, Eberhard"],["dc.date.accessioned","2022-10-06T13:33:14Z"],["dc.date.available","2022-10-06T13:33:14Z"],["dc.date.issued","2010"],["dc.identifier.doi","10.1016/j.mambio.2009.03.004"],["dc.identifier.pii","S1616504709000366"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/115581"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.issn","1616-5047"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","Ontogenetic and lung development in Tupaia belangeri during the early postnatal period"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]