Kraus, Cornelia

[["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","BMC Evolutionary Biology"],["dc.bibliographiccitation.volume","20"],["dc.contributor.author","Eckhardt, Falk"],["dc.contributor.author","Pauliny, Angela"],["dc.contributor.author","Rollings, Nicky"],["dc.contributor.author","Mutschmann, Frank"],["dc.contributor.author","Olsson, Mats"],["dc.contributor.author","Kraus, Cornelia"],["dc.contributor.author","Kappeler, Peter M."],["dc.date.accessioned","2021-04-14T08:32:23Z"],["dc.date.available","2021-04-14T08:32:23Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1186/s12862-020-01724-2"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/17689"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/83903"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.notes.intern","Merged from goescholar"],["dc.relation.eissn","1471-2148"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Stress-related changes in leukocyte profiles and telomere shortening in the shortest-lived tetrapod, Furcifer labordi"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","JDDG Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.volume","11"],["dc.contributor.author","Hofmann, L."],["dc.contributor.author","Brauns, B."],["dc.contributor.author","Kraus, S."],["dc.contributor.author","Wolff, Christian"],["dc.contributor.author","Thoms, K-M"],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Emmert, Steffen"],["dc.contributor.author","Kretschmer, Lutz"],["dc.contributor.author","Haenssle, Holger Andreas"],["dc.date.accessioned","2018-11-07T09:20:50Z"],["dc.date.available","2018-11-07T09:20:50Z"],["dc.date.issued","2013"],["dc.format.extent","927"],["dc.identifier.isi","000323202300082"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/28966"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.issn","1610-0379"],["dc.title","The in vivo confocal Laser-scanning Microscopy increases the pre-operative diagnostic Accuracy in cutaneous Neoplasia"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","229"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Neurogenetics"],["dc.bibliographiccitation.lastpage","238"],["dc.bibliographiccitation.volume","5"],["dc.contributor.author","Mannan, Ashraf U."],["dc.contributor.author","Roussa, Eleni"],["dc.contributor.author","Kraus, Cornelia"],["dc.contributor.author","Rickmann, Michael"],["dc.contributor.author","Maenner, Joerg"],["dc.contributor.author","Nayernia, K."],["dc.contributor.author","Krieglstein, Kerstin"],["dc.contributor.author","Reis, A."],["dc.contributor.author","Engel, Wolfgang"],["dc.date.accessioned","2018-11-07T10:43:34Z"],["dc.date.available","2018-11-07T10:43:34Z"],["dc.date.issued","2004"],["dc.description.abstract","We report a novel spontaneous mutation named nax in mice, which exhibit delayed hair appearance and ataxia in a homozygote state. Histological analyses of nax brain revealed an overall impairment of the cerebellar cortex. The classical cortical cytoarchitecture was disrupted, the inner granule cell layer was not obvious, the Purkinje cells were not aligned as a Purkinje cell layer, and Bergmann glias did not span the molecular layer. Furthermore, histological analyses of skin showed that the hair follicles were also abnormal. We mapped the nax locus between marker D2Mit158 and D2Mit100 within a region of 800 kb in the middle of chromosome 2 and identified a missense mutation (Gly244Glu) in Acp2, a lysosomal monoesterase. The Glu244 mutation does not affect the stability of the Acp2 transcript, however it renders the enzyme inactive. Ultrastructural analysis of nax cerebellum showed lysosomal storage bodies in nucleated cells, suggesting progressive degeneration as the underlying mechanism. Identification of Acp2 as the gene mutated in nax mice provides a valuable model system for studying the role of Acp2 in cerebellum and skin homeostasis."],["dc.identifier.doi","10.1007/s10048-004-0197-9"],["dc.identifier.isi","000226285100005"],["dc.identifier.pmid","15503243"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/47086"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","1364-6745"],["dc.title","Mutation in the gene encoding lysosomal acid phosphatase (Acp2) causes cerebellum and skin malformation in mouse"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","54"],["dc.bibliographiccitation.journal","Experimental Gerontology"],["dc.bibliographiccitation.lastpage","61"],["dc.bibliographiccitation.volume","61"],["dc.contributor.author","Hamalainen, Anni"],["dc.contributor.author","Dammhahn, Melanie"],["dc.contributor.author","Aujard, Fabienne"],["dc.contributor.author","Kraus, Cornelia"],["dc.date.accessioned","2018-11-07T10:03:59Z"],["dc.date.available","2018-11-07T10:03:59Z"],["dc.date.issued","2015"],["dc.description.abstract","Muscle strength reflects physical functioning, declines at old age and predicts health and survival in humans and laboratory animals. Age-associated muscle deterioration causes loss of strength and may impair fitness of wild animals. However, the effects of age and life-history characteristics on muscle strength in wild animals are unknown. We investigated environment-and sex-specific patterns of physical functioning by measuring grip strength in wild and captive gray mouse lemurs. We expected more pronounced strength senescence in captivity due to condition-dependent, extrinsic mortality found in nature. Males were predicted to be stronger but potentially experience more severe senescence than females as predicted by life history theory. We found similar senescent declines in captive males and females as well as wild females, whereas wild males showed little decline, presumably due to their early mortality. Captive animals were generally weaker and showed earlier declines than wild animals. Unexpectedly, females tended to be stronger than males, especially in the reproductive season. Universal intrinsic mechanisms (e. g. sarcopenia) likely cause the similar patterns of strength loss across settings. The female advantage in muscle strength merits further study; it may follow higher reproductive investment by males, or be an adaptation associated with female social dominance. (C) 2014 Elsevier Inc. All rights reserved."],["dc.identifier.doi","10.1016/j.exger.2014.11.017"],["dc.identifier.isi","000347468500008"],["dc.identifier.pmid","25446501"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/38595"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Pergamon-elsevier Science Ltd"],["dc.relation.issn","1873-6815"],["dc.relation.issn","0531-5565"],["dc.title","Losing grip: Senescent decline in physical strength in a small-bodied primate in captivity and in the wild"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1635"],["dc.bibliographiccitation.issue","1643"],["dc.bibliographiccitation.journal","Proceedings of the Royal Society B: Biological Sciences"],["dc.bibliographiccitation.lastpage","1644"],["dc.bibliographiccitation.volume","275"],["dc.contributor.author","Kraus, Cornelia"],["dc.contributor.author","Eberle, Manfred"],["dc.contributor.author","Kappeler, Peter"],["dc.date.accessioned","2017-09-07T11:48:57Z"],["dc.date.available","2017-09-07T11:48:57Z"],["dc.date.issued","2008"],["dc.description.abstract","Male excess mortality is widespread among mammals and frequently interpreted as a cost of sexually selected traits that enhance male reproductive success. Sex differences in the propensity to engage in risky behaviours are often invoked to explain the sex gap in survival. Here, we aim to isolate and quantify the survival consequences of two potentially risky male behavioural strategies in a small sexually monomorphic primate, the grey mouse lemur Microcebus murinus: (i) most females hibernate during a large part of the austral winter, whereas most males remain active and (ii) during the brief annual mating season males roam widely in search of receptive females. Using a 10-year capture-mark-recapture dataset from a population of M. murinus in Kirindy Forest, western Madagascar, we statistically modelled sex-specific seasonal survival probabilities. Surprisingly, we did not find any evidence for direct survival benefits of hibernation-winter survival did not differ between males and females. By contrast, during the breeding season males survived less well than females (sex gap: 16%). Consistent with the 'risky male behaviour' hypothesis, the period for lowered male survival was restricted to the short mating season. Thus, sex differences in survival in a promiscuous mammal can be substantial even in the absence of sexual dimorphism."],["dc.identifier.doi","10.1098/rspb.2008.0200"],["dc.identifier.gro","3150910"],["dc.identifier.pmid","18426751"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/7710"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.issn","0962-8452"],["dc.title","The costs of risky male behaviour: sex differences in seasonal survival in a small sexually monomorphic primate"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.peerReviewed","no"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1392"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","British Journal of Cancer"],["dc.bibliographiccitation.lastpage","1397"],["dc.bibliographiccitation.volume","112"],["dc.contributor.author","Kratz, Christian P."],["dc.contributor.author","Franke, L."],["dc.contributor.author","Peters, H."],["dc.contributor.author","Kohlschmidt, N."],["dc.contributor.author","Kazmierczak, B."],["dc.contributor.author","Finckh, U."],["dc.contributor.author","Bier, Andrea"],["dc.contributor.author","Eichhorn, B."],["dc.contributor.author","Blank, C."],["dc.contributor.author","Kraus, Cornelia"],["dc.contributor.author","Kohlhase, Juergen"],["dc.contributor.author","Pauli, Silke"],["dc.contributor.author","Wildhardt, G."],["dc.contributor.author","Kutsche, Kerstin"],["dc.contributor.author","Auber, Bernd"],["dc.contributor.author","Christmann, A."],["dc.contributor.author","Bachmann, N."],["dc.contributor.author","Mitter, D."],["dc.contributor.author","Cremer, F. W."],["dc.contributor.author","Mayer, K."],["dc.contributor.author","Daumer-Haas, C."],["dc.contributor.author","Nevinny-Stickel-Hinzpeter, C."],["dc.contributor.author","Oeffner, Frank"],["dc.contributor.author","Schlueter, G."],["dc.contributor.author","Gencik, M."],["dc.contributor.author","Ueberlacker, B."],["dc.contributor.author","Lissewski, Christina"],["dc.contributor.author","Schanze, I."],["dc.contributor.author","Greene, M. H."],["dc.contributor.author","Spix, C."],["dc.contributor.author","Zenker, Martin"],["dc.date.accessioned","2018-11-07T09:58:32Z"],["dc.date.available","2018-11-07T09:58:32Z"],["dc.date.issued","2015"],["dc.description.abstract","Background: Somatic mutations affecting components of the Ras-MAPK pathway are a common feature of cancer, whereas germline Ras pathway mutations cause developmental disorders including Noonan, Costello, and cardio-facio-cutaneous syndromes. These 'RASopathies' also represent cancer-prone syndromes, but the quantitative cancer risks remain unknown. Methods: We investigated the occurrence of childhood cancer including benign and malignant tumours of the central nervous system in a group of 735 individuals with germline mutations in Ras signalling pathway genes by matching their information with the German Childhood Cancer Registry. Results: We observed 12 cases of cancer in the entire RASopathy cohort vs 1.12 expected (based on German population-based incidence rates). This corresponds to a 10.5-fold increased risk of all childhood cancers combined (standardised incidence ratio (SIR) = 10.5, 95% confidence interval = 5.4-18.3). The specific cancers included juvenile myelomonocytic leukaemia = 4; brain tumour = 3; acute lymphoblastic leukaemia = 2; rhabdomyosarcoma = 2; and neuroblastoma = 1. The childhood cancer SIR in Noonan syndrome patients was 8.1, whereas that for Costello syndrome patients was 42.4. Conclusions: These data comprise the first quantitative evidence documenting that the germline mutations in Ras signalling pathway genes are associated with increased risks of both childhood leukaemia and solid tumours."],["dc.identifier.doi","10.1038/bjc.2015.75"],["dc.identifier.isi","000352989900012"],["dc.identifier.pmid","25742478"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/37381"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Nature Publishing Group"],["dc.relation.issn","1532-1827"],["dc.relation.issn","0007-0920"],["dc.title","Cancer spectrum and frequency among children with Noonan, Costello, and cardio-facio-cutaneous syndromes"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","137"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Conservation Genetics"],["dc.bibliographiccitation.lastpage","148"],["dc.bibliographiccitation.volume","21"],["dc.contributor.author","Yordy, Jennifer"],["dc.contributor.author","Kraus, Cornelia"],["dc.contributor.author","Hayward, Jessica J."],["dc.contributor.author","White, Michelle E."],["dc.contributor.author","Shannon, Laura M."],["dc.contributor.author","Creevy, Kate E."],["dc.contributor.author","Promislow, Daniel E. L."],["dc.contributor.author","Boyko, Adam R."],["dc.date.accessioned","2020-12-10T14:11:27Z"],["dc.date.available","2020-12-10T14:11:27Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1007/s10592-019-01240-x"],["dc.identifier.eissn","1572-9737"],["dc.identifier.issn","1566-0621"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/71080"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Body size, inbreeding, and lifespan in domestic dogs"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","173"],["dc.bibliographiccitation.journal","Animal Behaviour"],["dc.bibliographiccitation.lastpage","181"],["dc.bibliographiccitation.volume","93"],["dc.contributor.author","Kraus, Cornelia"],["dc.contributor.author","van Waveren, Cornelia"],["dc.contributor.author","Huebner, Franziska"],["dc.date.accessioned","2018-11-07T09:38:13Z"],["dc.date.available","2018-11-07T09:38:13Z"],["dc.date.issued","2014"],["dc.description.abstract","Dogs, Canis familiaris, and other domestic species are more skilled than great apes at following human communicative gestures in object choice tasks. Several hypotheses differentially emphasizing the role of domestication, socialization and experience have been put forward to account for this discrepancy. Recently, it has been suggested that the performance gap between apes and domestic species could be due instead to inconsistent methodologies across studies. Apes have generally been tested with the containers directly in front of them, and the experimenter performing the communicative cue behind the containers (central set-up). In contrast, domestic animals are usually placed at a larger distance with the human experimenter performing the cue in their direct line of sight and the containers peripheral on both sides of the experimenter (peripheral set-up). The distraction hypothesis posits that the close proximity of the food-associated containers in the central set-up proves too distracting for the test subjects, leading to an indiscriminate choice behaviour. Consistent with this idea, great apes are able to solve the peripheral version of the object choice task. To evaluate the distraction hypothesis further, we tested domestic dogs and cats, Felis catus, in the central as well as the peripheral set-up. As predicted, dogs' performance dropped significantly when tested in the central version of the task compared with the peripheral one. Cats performed as well as dogs in the peripheral version, but, intriguingly, their success levels did not decline significantly in the central version. We speculate that this might be due to cats cuing into the movement part of the pointing gesture. These findings partly support the distraction hypothesis and add to the evidence that domestic species do not necessarily have superior skills in reading human communicative cues. (C) 2014 The Association for the Study of Animal Behaviour. Published by Elsevier Ltd. All rights reserved."],["dc.identifier.doi","10.1016/j.anbehav.2014.04.026"],["dc.identifier.isi","000338712900022"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/33025"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Academic Press Ltd- Elsevier Science Ltd"],["dc.relation.issn","1095-8282"],["dc.relation.issn","0003-3472"],["dc.title","Distractible dogs, constant cats ? A test of the distraction hypothesis in two domestic species"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","655"],["dc.bibliographiccitation.lastpage","684"],["dc.contributor.author","Kappeler, Peter"],["dc.contributor.author","Kraus, Cornelia"],["dc.contributor.editor","Kappeler, Peter"],["dc.date.accessioned","2017-09-07T11:48:55Z"],["dc.date.available","2017-09-07T11:48:55Z"],["dc.date.issued","2010"],["dc.description.abstract","The behaviour of animals is the result of adaptations and constraints. To what extent a particular behaviour pattern can be attributed to the relative strengths of these two forces is crucial with respect to understanding the evolution of behaviour. Moreover, in the still young history of the study of animal behaviour, different conceptual approaches have placed very different emphases on the residual behavioural variability beyond adaptations and constraints. In this chapter, we retrace some of these paradigm shifts, offer an overview of different hierarchical levels at which behavioural variability occurs and summarise some of the mechanisms that generate or constrain it. Above the species level, phylogenetic constraints often limit behavioural variability because of a functional relationship between taxonwide life history traits and behaviour, but the exact nature of their underlying mechanisms remains obscure. Phylogenetic constraints exist at different taxonomic levels, and, as several examples from studies of primate behaviour indicate, they are also common in animals with relatively advanced cognitive abilities in which social learning is common. We therefore emphasise the importance of acknowledging the existence of such constraints in behavioural analyses. We also decompose behavioural variability further into variation within species, among individuals and within individuals over time and highlight some of the mechanisms responsible for generating and maintaining this variability. Our review suggests that the specific evolutionary history of a taxon will set the stage at which levels variability can arise, and that cognitive abilities appear to create surprisingly little additional freedom for behavioural variability."],["dc.identifier.doi","10.1007/978-3-642-02624-9_21"],["dc.identifier.gro","3150899"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/7698"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.notes.submitter","chake"],["dc.publisher","Springer"],["dc.publisher.place","Berlin, Heidelberg"],["dc.relation.isbn","978-3-642-02623-2"],["dc.relation.ispartof","Animal Behaviour: Evolution and Mechanisms"],["dc.title","Levels and mechanisms of behavioural variability"],["dc.type","book_chapter"],["dc.type.internalPublication","unknown"],["dc.type.peerReviewed","no"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","41"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Amphibia-Reptilia"],["dc.bibliographiccitation.lastpage","54"],["dc.bibliographiccitation.volume","40"],["dc.contributor.author","Eckhardt, Falk"],["dc.contributor.author","Kraus, Cornelia"],["dc.contributor.author","Kappeler, Peter M."],["dc.date.accessioned","2020-12-10T18:38:11Z"],["dc.date.available","2020-12-10T18:38:11Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1163/15685381-20181039"],["dc.identifier.eissn","0173-5373"],["dc.identifier.eissn","1568-5381"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77215"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Life histories, demographies and population dynamics of three sympatric chameleon species (Furcifer spp.) from western Madagascar"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]