Now showing 1 - 10 of 11
  • 2005Conference Abstract
    [["dc.bibliographiccitation.firstpage","525"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","Das Gesundheitswesen"],["dc.bibliographiccitation.lastpage","526"],["dc.bibliographiccitation.volume","67"],["dc.contributor.author","Schmidt, Constanze"],["dc.contributor.author","Kohlmann, Thomas"],["dc.contributor.author","Lange, K."],["dc.contributor.author","Pfingsten, M."],["dc.contributor.author","Hasenbring, M."],["dc.contributor.author","Basler, H.-D."],["dc.contributor.author","Eich, W."],["dc.contributor.author","Raspe, H."],["dc.date.accessioned","2018-11-07T09:11:24Z"],["dc.date.available","2018-11-07T09:11:24Z"],["dc.date.issued","2005"],["dc.identifier.isi","000231627100081"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/26712"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Georg Thieme Verlag Kg"],["dc.publisher.place","Stuttgart"],["dc.title","Graduated back pains and the demands for medical acomplishments - Results of the DFRS back pain study"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]
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  • 2005Conference Paper
    [["dc.bibliographiccitation.firstpage","227"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Journal of Neuropsychiatry"],["dc.bibliographiccitation.lastpage","231"],["dc.bibliographiccitation.volume","17"],["dc.contributor.author","Kropp, Silke"],["dc.contributor.author","Kern, V."],["dc.contributor.author","Lange, K."],["dc.contributor.author","Degner, Detlef"],["dc.contributor.author","Hajak, Goran"],["dc.contributor.author","Kornhuber, Johannes"],["dc.contributor.author","Ruther, Eckart"],["dc.contributor.author","Emrich, H. M."],["dc.contributor.author","Schneider, Udo"],["dc.contributor.author","Bleich, Stefan"],["dc.date.accessioned","2018-11-07T11:20:37Z"],["dc.date.available","2018-11-07T11:20:37Z"],["dc.date.issued","2005"],["dc.description.abstract","Neurotoxicity of first-generation antipsychotics: (FGAs) may be involved in lipid peroxidation, which is the pathogenesis of extrapyramidal symptoms, including tardive dyskinesia (TD). Blood samples at day 0, 7, and 21 drawn from patients taking antipsychotics were analyzed for malondialdehyde (MDA) in plasma, a marker of lipid peroxidation, by high-performance liquid chromatography. Of 115 patients enrolled, 92 patients completed the study. Most MDA levels were within normal ranges (<1.0 mu mol/liter). Malondialdehyde levels in patients receiving clozapine (p = 0.002), quetiapine (p = 0.003), amisulpride (p = 0.008), and risperidone (p = 0.008) were significantly lower than within the first generation antipsychotic group. The authors conclude that lipid peroxidation is significantly higher in treatment with FGAs."],["dc.identifier.doi","10.1176/appi.neuropsych.17.2.227"],["dc.identifier.isi","000229541000014"],["dc.identifier.pmid","15939978"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/55581"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Psychiatric Publishing, Inc"],["dc.publisher.place","Arlington"],["dc.relation.conference","Annual Meeting of the Nordic-Association-for-Psychiatric-Epidemiology"],["dc.relation.eventlocation","REYKJAVIK, ICELAND"],["dc.relation.issn","1545-7222"],["dc.relation.issn","0895-0172"],["dc.title","Oxidative stress during treatment with first- and second-generation antipsychotics"],["dc.type","conference_paper"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2013Journal Article
    [["dc.bibliographiccitation.firstpage","103"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","European Journal of Vascular and Endovascular Surgery"],["dc.bibliographiccitation.lastpage","109"],["dc.bibliographiccitation.volume","46"],["dc.contributor.author","Nagy, G. Cs."],["dc.contributor.author","Wunsch, M."],["dc.contributor.author","Jordan, A."],["dc.contributor.author","Lange, K."],["dc.date.accessioned","2018-11-07T09:23:00Z"],["dc.date.available","2018-11-07T09:23:00Z"],["dc.date.issued","2013"],["dc.description.abstract","Objective: We describe and present the results of our novel technique for eversion endarterectomy of the external iliac artery (EIA). Methods: For our prospective follow-up study, antegrade eversion endarterectomy (AEEA) of the EIA was mostly performed as a bail-out procedure, it (endovascular-assisted) remote endarterectomy from the groin had failed. Postoperative clinical and hemodynamic changes were reported according to the recommendations of the Society for Vascular Surgery. To evaluate the data, we used the Kaplan-Meier product limit method. Results: Thirty patients (mean age 65.5 years) underwent AEEA on 33 El As for atherosclerotic occlusive disease over a 10-year period. The mean follow-up was 50 months. The primary technical success rate was 100%. The 30-day mortality was 0. There were no early occlusions. Two patients required redo surgery for retroperitoneal haematomas. Postoperative improvement was marked in 30%, moderate in 64% and minimal in 6%, explained by 21 (64%) concomitant occlusions of the superficial femoral arteries. The 1-, 3- and 5-year primary patency rates were 100%, 96% and 90%, and primary assisted patency rates were 100%, 96% and 96% respectively. Fourteen patients (47%) died during the long follow-up period from unrelated causes. Conclusion: AEEA is a safe autologous surgical technique with promising results. (C) 2013 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved."],["dc.identifier.doi","10.1016/j.ejvs.2013.03.029"],["dc.identifier.isi","000321883200019"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/29476"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","W B Saunders Co Ltd"],["dc.relation.issn","1532-2165"],["dc.relation.issn","1078-5884"],["dc.title","Antegrade Eversion Endarterectomy of the External Iliac Artery"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2002Journal Article
    [["dc.bibliographiccitation.firstpage","163"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Leukemia Research"],["dc.bibliographiccitation.lastpage","168"],["dc.bibliographiccitation.volume","26"],["dc.contributor.author","Mueller, A."],["dc.contributor.author","Lange, K."],["dc.contributor.author","Gaiser, T."],["dc.contributor.author","Hofmann, M."],["dc.contributor.author","Bartels, H."],["dc.contributor.author","Feller, A. C."],["dc.contributor.author","Merz, H."],["dc.date.accessioned","2018-11-07T10:32:17Z"],["dc.date.available","2018-11-07T10:32:17Z"],["dc.date.issued","2002"],["dc.description.abstract","Apart from endothelial cells, the receptor tyrosine kinase TEK/Tie-2 is also expressed by primitive hematopoietic stem cells. While the role of this receptor and its ligand angiopoietin-1 (ang-1) during angiogenesis has been intensively studied before, little is known about their function in normal or malignant hematopoiesis. Recently several studies suggested that TEK plays an important role in the proliferation of primitive hematopoietic cells. We. therefore, analyzed blood cells of healthy donors and leukemia patients for expression of TEK and ang-1 by semiquantitative reverse transcription-polymerase chain reaction (RT-PCR) and Northern blotting. We found an increased expression of the receptor and its ligand in 11 of 17 cases of acute and chronic myeloid leukemia (CML) but not in four lymphocytic leukemias or five myeloid leukemias in remission. Abundant ang-1 message could also be detected in 4/6 myeloid and 1/9 cell lines of lymphocytic origin, but only one cell line co-expressed the TEK receptor. suggesting that ang-1 and TEK were probably expressed by different subsets of cells in the leukemic samples. Recently, several studies have indicated that angiogenic factors like ang-1 and vascular endothelial growth factor can enhance the proliferation of normal and malignant hematopoietic cells. The expression of both the TEK receptor and its ligand in acute myeloid leukemia (AML) and CML patients might, therefore, suggest an involvement of these genes in the pathogenesis of myeloproliferative disorders. (C) 2002 Elsevier Science Ltd. All rights reserved."],["dc.identifier.doi","10.1016/S0145-2126(01)00110-2"],["dc.identifier.isi","000173774400005"],["dc.identifier.pmid","11755466"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/44315"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Pergamon-elsevier Science Ltd"],["dc.relation.issn","0145-2126"],["dc.title","Expression of angiopoietin-1 and its receptor TEK in hematopoietic cells from patients with myeloid leukemia"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2002Conference Abstract
    [["dc.bibliographiccitation.journal","European Heart Journal"],["dc.bibliographiccitation.volume","23"],["dc.contributor.author","Ferrari, M."],["dc.contributor.author","Hellige, Gerhard"],["dc.contributor.author","Schlosser, M."],["dc.contributor.author","Lang, K."],["dc.contributor.author","Frerichs, Inez"],["dc.contributor.author","Mueller, E."],["dc.contributor.author","Eisold, G."],["dc.contributor.author","Figulla, H. R."],["dc.date.accessioned","2018-11-07T10:12:56Z"],["dc.date.available","2018-11-07T10:12:56Z"],["dc.date.issued","2002"],["dc.format.extent","156"],["dc.identifier.isi","000179753300583"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/40331"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","W B Saunders Co Ltd"],["dc.publisher.place","London"],["dc.relation.conference","Congress of the European-Society-of-Cardiology"],["dc.relation.eventlocation","BERLIN, GERMANY"],["dc.relation.issn","0195-668X"],["dc.title","Percutaneous aortic valve replacement with a self-expanding stent - First animal results"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2018Journal Article
    [["dc.bibliographiccitation.firstpage","224"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Der Diabetologe"],["dc.bibliographiccitation.lastpage","230"],["dc.bibliographiccitation.volume","14"],["dc.contributor.author","Böttcher, I."],["dc.contributor.author","von dem Berge, T."],["dc.contributor.author","Lange, K."],["dc.contributor.author","Marquardt, E."],["dc.contributor.author","Freiberg, C."],["dc.contributor.author","Galuschka, L."],["dc.contributor.author","Müller, I."],["dc.contributor.author","Roloff, F."],["dc.contributor.author","Semler, K."],["dc.contributor.author","Hermann, J."],["dc.contributor.author","Aschemeier, B."],["dc.contributor.author","Danne, T."],["dc.contributor.author","Kordonouri, O."],["dc.date.accessioned","2020-12-10T14:12:00Z"],["dc.date.available","2020-12-10T14:12:00Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1007/s11428-018-0345-8"],["dc.identifier.eissn","1860-9724"],["dc.identifier.issn","1860-9716"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/71275"],["dc.language.iso","de"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Vermeidung erkrankungsspezifischer Komplikationen bei Kindern"],["dc.title.alternative","Avoiding disease-specific complications in children. The Fr1dolin study in Lower Saxony"],["dc.title.subtitle","Früherkennungsprojekt: Fr1dolin-Studie in Niedersachsen"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2013Journal Article
    [["dc.bibliographiccitation.firstpage","228"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Journal of Oral Rehabilitation"],["dc.bibliographiccitation.lastpage","237"],["dc.bibliographiccitation.volume","40"],["dc.contributor.author","Rinke, Sven"],["dc.contributor.author","Schäfer, S."],["dc.contributor.author","Lange, K."],["dc.contributor.author","Gersdorff, Nikolaus"],["dc.contributor.author","Roediger, Matthias"],["dc.date.accessioned","2018-11-07T09:27:57Z"],["dc.date.available","2018-11-07T09:27:57Z"],["dc.date.issued","2013"],["dc.description.abstract","This practice-based study evaluates the clinical performance of conventionally luted metalceramic and zirconia molar crowns fabricated with pronounced anatomical core design and a prolonged cooling period of the veneering porcelain. Fifty-three patients were treated from 07/2008 until 07/2009 with either metalceramic crowns (MCC) (high-noble alloy+low-fusing porcelain) or zirconia crowns (Cercon System, DeguDent, Germany). Forty-nine patients (30 women/19 men) with 100 restorations (metalceramic: 48/zirconia: 52, mean observational period: 36 center dot 5 +/- 6months) participated in a clinical follow-up examination and were included in the study. Time-dependent survival (in situ criteria), success (event-free restorations) and chipping rates (defects of the veneering ceramics) were calculated according to the KaplanMeier method and analysed in relation to the crown fabrication technique, using a Cox regression model (P<0 center dot 05). Three complete failures (metalceramic: 1, zirconia: 2) were recorded (survival rate after 3years: metalceramic: 97 center dot 6%, zirconia: 95 center dot 2%). Of the metalceramic restorations, 90 center dot 9% remained event-free (two ceramic fractures, one endodontic treatment), whereas the success rate for the zirconia was 86 center dot 8% (two ceramic fractures, one endodontic treatment, one secondary caries). No significant differences in survival (P=0 center dot 53), success (P=0 center dot 49) and ceramic fracture rates (P=0 center dot 57) were detected. The combination of a pronounced anatomical core design and a modified firing of the veneering porcelain for the fabrication of zirconia molar crowns resulted in a 3-year survival, success and chipping rate comparable to MCC."],["dc.description.sponsorship","DeguDent GmbH; Dentsply DeTrey"],["dc.identifier.doi","10.1111/joor.12018"],["dc.identifier.isi","000314470100010"],["dc.identifier.pmid","23211063"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/30657"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","0305-182X"],["dc.title","Practice-based clinical evaluation of metalceramic and zirconia molar crowns: 3-year results"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]
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  • 2012Journal Article
    [["dc.bibliographiccitation.firstpage","1090"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Computational Statistics & Data Analysis"],["dc.bibliographiccitation.lastpage","1102"],["dc.bibliographiccitation.volume","56"],["dc.contributor.author","Konietschke, Frank"],["dc.contributor.author","Harrar, S. W."],["dc.contributor.author","Lange, K."],["dc.contributor.author","Brunner, E."],["dc.date.accessioned","2018-11-07T09:11:01Z"],["dc.date.available","2018-11-07T09:11:01Z"],["dc.date.issued","2012"],["dc.description.abstract","Nonparametric methods for matched pairs with data missing completely at random are considered. It is not assumed that the observations are coming from distribution functions belonging to a certain parametric or semi-parametric family. In particular, the distributions can have different shapes under the null hypothesis. Hence, the so-called nonparametric Behrens-Fisher problem for matched pairs with missing data is considered. Moreover, a new approach for confidence intervals for nonparametric effects is presented. In particular, no restriction on the ratio of the number of complete and incomplete cases is required to derive the asymptotic results. Simulations show that for arbitrary settings of complete data and missing values, the resulting confidence intervals maintain the pre-assigned coverage probability quite accurately. Regarding the power, none of the proposed tests is uniformly superior to the other. A real data set illustrates the application. (C) 2011 Elsevier B.V. All rights reserved."],["dc.description.sponsorship","German Research Foundation [Br-655/16-1]"],["dc.identifier.doi","10.1016/j.csda.2011.03.022"],["dc.identifier.isi","000301688100010"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/26628"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Bv"],["dc.relation.issn","0167-9473"],["dc.title","Ranking procedures for matched pairs with missing data - Asymptotic theory and a small sample approximation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2010Journal Article
    [["dc.bibliographiccitation.firstpage","581"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","International Endodontic Journal"],["dc.bibliographiccitation.lastpage","589"],["dc.bibliographiccitation.volume","43"],["dc.contributor.author","Roedig, Tina"],["dc.contributor.author","Sedghi, M."],["dc.contributor.author","Konietschke, Frank"],["dc.contributor.author","Lange, K."],["dc.contributor.author","Ziebolz, Dirk"],["dc.contributor.author","Huelsmann, Micbael"],["dc.date.accessioned","2018-11-07T08:41:44Z"],["dc.date.available","2018-11-07T08:41:44Z"],["dc.date.issued","2010"],["dc.description.abstract","P>Aim To compare of the efficacy of syringe irrigation, RinsEndo (R) (Durr Dental, Bietigheim, Germany) and passive ultrasonic irrigation (PUI) in the removal of dentinal debris from simulated irregularities in root canals with different apical sizes. Methodology Thirty extracted human pre-molars were randomly divided into three groups (n = 10) followed by root canal preparation with rotary FlexMaster (R) NiTi instruments (VDW, Munich, Germany) to size 30, 0.02 taper (group 1), size 40, 0.02 taper (group 2) or size 50, 0.02 taper (group 3). The teeth were split longitudinally, and a standard groove and three hemispherical-shaped cavities were cut into the root canal halves. Grooves and cavities were filled with dentinal debris before each irrigation procedure and the root halves were reassembled. In all groups three different irrigation procedures were performed with 30 mL NaOCl (1%) and (i) syringe, (ii) RinsEndo (R) and (iii) PUI. The amount of remaining debris was evaluated under a microscope with 30x magnification and a four score system. The data were analysed with a non-parametric analysis of covariance and multiple comparisons using the Tukey adjustment (P = 0.05). Results Passive ultrasonic irrigation removed debris significantly better from the artificial canal irregularities than RinsEndo (R) and syringe irrigation irrespective of the root canal diameter. Only in group 1 (30, 0.02 taper) the difference between PUI and RinsEndo (R) was not statistically significant (P = 0.99). RinsEndo (R) demonstrated significantly better results than syringe irrigation in all groups (P < 0.001). Conclusions Ultrasonic irrigation is more effective than syringe irrigation or RinsEndo (R) in removing debris from artificial extensions in straight root canals."],["dc.identifier.doi","10.1111/j.1365-2591.2010.01721.x"],["dc.identifier.isi","000278566500006"],["dc.identifier.pmid","20636517"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/19533"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","0143-2885"],["dc.relation.orgunit","Poliklinik für Präventive Zahnmedizin, Parodontologie und Kariologie"],["dc.title","Efficacy of syringe irrigation, RinsEndo (R) and passive ultrasonic irrigation in removing debris from irregularities in root canals with different apical sizes"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2017Journal Article
    [["dc.bibliographiccitation.firstpage","3509"],["dc.bibliographiccitation.issue","14"],["dc.bibliographiccitation.journal","Biogeosciences"],["dc.bibliographiccitation.lastpage","3524"],["dc.bibliographiccitation.volume","14"],["dc.contributor.author","Matson, Amanda L."],["dc.contributor.author","Corre, Marife D."],["dc.contributor.author","Langs, Kerstin"],["dc.contributor.author","Veldkamp, Edzo"],["dc.date.accessioned","2019-07-09T11:44:36Z"],["dc.date.available","2019-07-09T11:44:36Z"],["dc.date.issued","2017"],["dc.description.abstract","Tropical lowland forest soils are significant sources and sinks of trace gases. In order to model soil trace gas flux for future climate scenarios, it is necessary to be able to predict changes in soil trace gas fluxes along natural gradients of soil fertility and climatic characteristics. We quantified trace gas fluxes in lowland forest soils at five locations in Panama, which encompassed orthogonal precipitation and soil fertility gradients. Soil trace gas fluxes were measured monthly for 1 (NO) or 2 (CO2, CH4, N2O) years (2010–2012) using vented dynamic (for NO only) or static chambers with permanent bases. Across the five sites, annual fluxes ranged from 8.0 to 10.2 Mg CO2-C, −2.0 to −0.3 kg CH4-C, 0.4 to 1.3 kg N2O-N and −0.82 to −0.03 kg NO-N ha−1 yr−1. Soil CO2 emissions did not differ across sites, but they did exhibit clear seasonal differences and a parabolic pattern with soil moisture across sites. All sites were CH4 sinks; within-site fluxes were largely controlled by soil moisture, whereas fluxes across sites were positively correlated with an integrated index of soil fertility. Soil N2O fluxes were low throughout the measurement years, but the highest emissions occurred at a mid-precipitation site with high soil N availability. Net negative NO fluxes at the soil surface occurred at all sites, with the most negative fluxes at the low-precipitation site closest to Panama City; this was likely due to high ambient NO concentrations from anthropogenic sources. Our study highlights the importance of both short-term (climatic) and long-term (soil and site characteristics) factors in predicting soil trace gas fluxes."],["dc.identifier.doi","10.5194/bg-14-3509-2017"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14837"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/59048"],["dc.language.iso","en"],["dc.relation.issn","1726-4189"],["dc.subject.ddc","570"],["dc.title","Soil trace gas fluxes along orthogonal precipitation and soil fertility gradients in tropical lowland forests of Panama"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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