Fernandes dos Reis, Micael

[["dc.bibliographiccitation.artnumber","e25520"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","PLoS One"],["dc.bibliographiccitation.volume","6"],["dc.contributor.author","Reis, Micael"],["dc.contributor.author","Vieira, Cristina P."],["dc.contributor.author","Morales-Hojas, Ramiro"],["dc.contributor.author","Aguiar, Bruno"],["dc.contributor.author","Rocha, Hélder"],["dc.contributor.author","Schlötterer, Christian"],["dc.contributor.author","Vieira, Jorge"],["dc.date.accessioned","2020-06-29T06:54:33Z"],["dc.date.available","2020-06-29T06:54:33Z"],["dc.date.issued","2011"],["dc.description.abstract","The molecular basis of short term cold resistance (indexed as chill-coma recovery time) has been mostly addressed in D. melanogaster, where candidate genes (Dca (also known as smp-30) and Frost (Fst)) have been identified. Nevertheless, in Drosophila, the ability to tolerate short term exposure to low temperatures evolved several times independently. Therefore, it is unclear whether variation in the same candidate genes is also responsible for short term cold resistance in distantly related Drosophila species. It should be noted that Dca is a candidate gene for cold resistance in the Sophophora subgenus only, since there is no orthologous gene copy in the Drosophila subgenus. Here we show that, in D. americana (Drosophila subgenus), there is a north-south gradient for a variant at the 5' non-coding region of regucalcin (a Dca-like gene; in D. melanogaster the proteins encoded by the two genes share 71.9% amino acid identities) but in our D. americana F2 association experiment there is no association between this polymorphism and chill-coma recovery times. Moreover, we found no convincing evidence that this gene is up-regulated after cold shock in both D. americana and D. melanogaster. Size variation in the Fst PEST domain (putatively involved in rapid protein degradation) is observed when comparing distantly related Drosophila species, and is associated with short term cold resistance differences in D. americana. Nevertheless, this effect is likely through body size variation. Moreover, we show that, even at two hours after cold shock, when up-regulation of this gene is maximal in D. melanogaster (about 48 fold expression change), in D. americana this gene is only moderately up-regulated (about 3 fold expression change). Our work thus shows that there are important differences regarding the molecular basis of cold resistance in distantly related Drosophila species."],["dc.identifier.doi","10.1371/journal.pone.0025520"],["dc.identifier.pmid","21991316"],["dc.identifier.scopus","2-s2.0-80053451103"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/66757"],["dc.identifier.url","http://www.scopus.com/inward/record.url?eid=2-s2.0-80053451103&partnerID=MN8TOARS"],["dc.language.iso","en"],["dc.relation.eissn","1932-6203"],["dc.relation.issn","1932-6203"],["dc.title","A comparative study of the short term cold resistance response in distantly related Drosophila species: The role of regucalcin and Frost"],["dc.type","journal_article"],["dc.type.internalPublication","no"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","3152"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","Genome Biology and Evolution"],["dc.bibliographiccitation.lastpage","3166"],["dc.bibliographiccitation.volume","10"],["dc.contributor.author","Reis, Micael"],["dc.contributor.author","Vieira, Cristina P."],["dc.contributor.author","Lata, Rodrigo"],["dc.contributor.author","Posnien, Nico"],["dc.contributor.author","Vieira, Jorge"],["dc.date.accessioned","2019-08-09T07:10:34Z"],["dc.date.accessioned","2020-06-25T10:16:52Z"],["dc.date.available","2019-08-09T07:10:34Z"],["dc.date.available","2020-06-25T10:16:52Z"],["dc.date.issued","2018"],["dc.description.abstract","In Drosophila, large variations in rearrangement rate have been reported among different lineages and among Muller's elements. Nevertheless, the mechanisms that are involved in the generation of inversions, their increase in frequency, as well as their impact on the genome are not completely understood. This is in part due to the lack of comparative studies on species distantly related to Drosophila melanogaster. Therefore, we sequenced and assembled the genomes of two species of the virilis phylad (Drosophila novamexicana [15010-1031.00] and Drosophila americana [SF12]), which are diverging from D. melanogaster for more than 40 Myr. Based on these data, we identified the precise location of six novel inversion breakpoints. A molecular characterization provided clear evidence that DAIBAM (a miniature inverted-repeat transposable element) was involved in the generation of eight out of the nine inversions identified. In contrast to what has been previously reported for D. melanogaster and close relatives, ectopic recombination is thus the prevalent mechanism of generating inversions in species of the virilis phylad. Using pool-sequencing data for three populations of D. americana, we also show that common polymorphic inversions create a high degree of genetic differentiation between populations for chromosomes X, 4, and 5 over large physical distances. We did not find statistically significant differences in expression levels between D. americana (SF12) and D. novamexicana (15010-1031.00) strains for the three genes surveyed (CG9588, Fig 4, and fab1) flanking three inversion breakpoints."],["dc.identifier.doi","10.1093/gbe/evy239"],["dc.identifier.pmid","30376068"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/16345"],["dc.identifier.scopus","2-s2.0-85060237162"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/62355"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/66745"],["dc.identifier.url","http://www.scopus.com/inward/record.url?eid=2-s2.0-85060237162&partnerID=MN8TOARS"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","final"],["dc.relation.eissn","1759-6653"],["dc.relation.issn","1759-6653"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Origin and Consequences of Chromosomal Inversions in the virilis Group of Drosophila"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","573"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Heredity"],["dc.bibliographiccitation.lastpage","578"],["dc.bibliographiccitation.volume","102"],["dc.contributor.author","Morales-Hojas, R."],["dc.contributor.author","Vieira, C. P."],["dc.contributor.author","Reis, M."],["dc.contributor.author","Vieira, J."],["dc.date.accessioned","2020-06-29T06:59:37Z"],["dc.date.available","2020-06-29T06:59:37Z"],["dc.date.issued","2009"],["dc.description.abstract","Five immunity-related genes previously reported to be evolving under positive selection in Drosophila melanogaster and D. simulans have been analysed across the Drosophila genus using two types of approaches, random-site and branch-site likelihood models as well as the proportion of synonymous and non-synonymous variation within and between species. Different selective pressures have been detected in the sample of genes, one showing evidence for adaptive evolution across the phylogeny of Drosophila and two showing lineage-specific positive selection. Furthermore, amino-acid sites identified as being under positive selection in the melanogaster and the virilis groups are different, suggesting that the evolution of the proteins in these two divergent groups may have been shaped by different pathogens."],["dc.identifier.doi","10.1038/hdy.2009.11"],["dc.identifier.scopus","2-s2.0-67349177764"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/66759"],["dc.identifier.url","http://www.scopus.com/inward/record.url?eid=2-s2.0-67349177764&partnerID=MN8TOARS"],["dc.language.iso","en"],["dc.relation.issn","0018-067X"],["dc.relation.issn","1365-2540"],["dc.title","Comparative analysis of five immunity-related genes reveals different levels of adaptive evolution in the virilis and melanogaster groups of Drosophila"],["dc.type","journal_article"],["dc.type.internalPublication","no"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1549"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Journal of Evolutionary Biology"],["dc.bibliographiccitation.lastpage","1561"],["dc.bibliographiccitation.volume","27"],["dc.contributor.author","Sillero, N."],["dc.contributor.author","Reis, Micael"],["dc.contributor.author","Vieira, C. P."],["dc.contributor.author","Vieira, J."],["dc.contributor.author","Morales-Hojas, R."],["dc.date.accessioned","2020-06-25T10:07:27Z"],["dc.date.available","2020-06-25T10:07:27Z"],["dc.date.issued","2014"],["dc.description.abstract","The study of ecological niche evolution is fundamental for understanding how the environment influences species' geographical distributions and their adaptation to divergent environments. Here, we present a study of the ecological niche, demographic history and thermal performance (locomotor activity, developmental time and fertility/viability) of the temperate species Drosophila americana and its two chromosomal forms. Temperature is the environmental factor that contributes most to the species' and chromosomal forms' ecological niches, although precipitation is also important in the model of the southern populations. The past distribution model of the species predicts a drastic reduction in the suitable area for the distribution of the species during the last glacial maximum (LGM), suggesting a strong bottleneck. However, DNA analyses did not detect a bottleneck signature during the LGM. These contrasting results could indicate that D. americana niche preference evolves with environmental change, and thus, there is no evidence to support niche conservatism in this species. Thermal performance experiments show no difference in the locomotor activity across a temperature range of 15 to 38 °C between flies from the north and the south of its distribution. However, we found significant differences in developmental time and fertility/viability between the two chromosomal forms at the model's optimal temperatures for the two forms. However, results do not indicate that they perform better for the traits studied here in their respective optimal niche temperatures. This suggests that behaviour plays an important role in thermoregulation, supporting the capacity of this species to adapt to different climatic conditions across its latitudinal distribution."],["dc.identifier.doi","10.1111/jeb.12400"],["dc.identifier.pmid","24835376"],["dc.identifier.scopus","2-s2.0-84904423388"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/66741"],["dc.identifier.url","http://www.scopus.com/inward/record.url?eid=2-s2.0-84904423388&partnerID=MN8TOARS"],["dc.language.iso","en"],["dc.relation.eissn","1420-9101"],["dc.relation.issn","1010-061X"],["dc.title","Niche evolution and thermal adaptation in the temperate species Drosophila americana"],["dc.type","journal_article"],["dc.type.internalPublication","no"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","48"],["dc.bibliographiccitation.issue","1-2"],["dc.bibliographiccitation.journal","Gene"],["dc.bibliographiccitation.lastpage","55"],["dc.bibliographiccitation.volume","425"],["dc.contributor.author","Reis, Micael"],["dc.contributor.author","Vieira, C. P."],["dc.contributor.author","Morales-Hojas, R."],["dc.contributor.author","Vieira, J."],["dc.date.accessioned","2020-06-25T10:20:38Z"],["dc.date.available","2020-06-25T10:20:38Z"],["dc.date.issued","2008"],["dc.description.abstract","In Drosophila, at the population and species level, fixation of a TE insertion is an unlikely fate. Of the few reported fixations at the species level most involve non-LTR retroelements. In this work we report the fixation of a non-LTR retroelement in five species (Drosophila littoralis, Drosophila virilis, Drosophila lummei, Drosophila americana and Drosophila novamexicana) of the virilis group of Drosophila. In most species, this TE insertion is being lost through the accumulation of small deletions, but there is also evidence for the accumulation of large deletions. In the americana lineage an insertion of about 900 bp of the non-LTR retroelement is a marker for the Xc inversion. This insertion is, at most, 80 kb away from the basal Xc inversion breakpoint. The presence of a bilbo-like element in D. littoralis but not in D. kanekoi, suggests that D. littoralis is more closely related to species of the virilis phylad than to species of the montana phylad, which is in contrast with the traditional view. Nevertheless, the phylogenetic analyses here performed using a 7 gene dataset suggest that D. littoralis is indeed more closely related to species of the virilis phylad than to species of the montana phylad. The re-evaluation of the phylogenetic relationship of the species of the virilis group, under the assumption of a relaxed molecular clock, results in an estimated age of the bilbo-like element insertion of at least 7.5 Mya."],["dc.identifier.doi","10.1016/j.gene.2008.08.010"],["dc.identifier.scopus","2-s2.0-53149089756"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/66747"],["dc.identifier.url","http://www.scopus.com/inward/record.url?eid=2-s2.0-53149089756&partnerID=MN8TOARS"],["dc.language.iso","en"],["dc.relation.issn","0378-1119"],["dc.title","An old bilbo-like non-LTR retroelement insertion provides insight into the relationship of species of the virilis group"],["dc.type","journal_article"],["dc.type.internalPublication","no"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e0138758"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","PLoS One"],["dc.bibliographiccitation.volume","10"],["dc.contributor.author","Reis, Micael"],["dc.contributor.author","Valer, Felipe B."],["dc.contributor.author","Vieira, Cristina P."],["dc.contributor.author","Vieira, Jorge"],["dc.date.accessioned","2020-06-29T06:52:28Z"],["dc.date.available","2020-06-29T06:52:28Z"],["dc.date.issued","2015"],["dc.description.abstract","Diapause is a period of arrested development which is controlled physiologically, preprogrammed environmentally and characterized by metabolic depression that can occur during any stage of insect development. Nevertheless, in the genus Drosophila, diapause is almost always associated with the cessation of ovarian development and reproductive activity in adult females. In this work, we show that, in D. americana (a temperate species of the virilis group), diapause is a genetically determined delay in ovarian development that is triggered by temperature and/or photoperiod. Moreover, we show that in this species diapause incidence increases with latitude, ranging from 13% in the southernmost to 91% in the northernmost range of the distribution. When exposed to diapause inducing conditions, both diapausing and non-diapausing females show a 10% increase in lifespan, that is further increased by 18.6% in diapausing females, although senescence is far from being negligible.ActinD1 expression levels suggest that diapausing females are biologically much younger than their chronological age, and that the fly as a whole, rather than the ovarian developmental one, which is phenotypically more evident, is delayed by diapause. Therefore, diapause candidate genes that show expression levels that are compatible with flies younger than their chronological age may not necessarily play a role in reproductive diapause and in adaptation to seasonally varying environmental conditions [corrected]."],["dc.identifier.doi","10.1371/journal.pone.0138758"],["dc.identifier.pmid","26398836"],["dc.identifier.scopus","2-s2.0-84946949500"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/66756"],["dc.identifier.url","http://www.scopus.com/inward/record.url?eid=2-s2.0-84946949500&partnerID=MN8TOARS"],["dc.language.iso","en"],["dc.relation.eissn","1932-6203"],["dc.relation.issn","1932-6203"],["dc.title","Drosophila Americana diapausing females show features typical of young flies"],["dc.type","journal_article"],["dc.type.internalPublication","no"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","492"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","Genes"],["dc.bibliographiccitation.volume","10"],["dc.contributor.author","Buchberger, Elisa"],["dc.contributor.author","Reis, Micael"],["dc.contributor.author","Lu, Ting-Hsuan"],["dc.contributor.author","Posnien, Nico"],["dc.date.accessioned","2019-08-09T06:52:58Z"],["dc.date.accessioned","2020-06-25T10:15:54Z"],["dc.date.available","2019-08-09T06:52:58Z"],["dc.date.available","2020-06-25T10:15:54Z"],["dc.date.issued","2019"],["dc.description.abstract","Research in various fields of evolutionary biology has shown that divergence in gene expression is a key driver for phenotypic evolution. An exceptional contribution of cis-regulatory divergence has been found to contribute to morphological diversification. In the light of these findings, the analysis of genome-wide expression data has become one of the central tools to link genotype and phenotype information on a more mechanistic level. However, in many studies, especially if general conclusions are drawn from such data, a key feature of gene regulation is often neglected. With our article, we want to raise awareness that gene regulation and thus gene expression is highly context dependent. Genes show tissue- and stage-specific expression. We argue that the regulatory context must be considered in comparative expression studies."],["dc.identifier.doi","10.3390/genes10070492"],["dc.identifier.pmid","31261769"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/16344"],["dc.identifier.scopus","2-s2.0-85069647849"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/62354"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/66744"],["dc.identifier.url","http://www.scopus.com/inward/record.url?eid=2-s2.0-85069647849&partnerID=MN8TOARS"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","final"],["dc.relation.issn","2073-4425"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Cloudy with a Chance of Insights: Context Dependent Gene Regulation and Implications for Evolutionary Studies"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Pharmacopsychiatry"],["dc.bibliographiccitation.volume","55"],["dc.contributor.author","Eichentopf, L."],["dc.contributor.author","Hiemke, C."],["dc.contributor.author","Conca, A."],["dc.contributor.author","Engelmann, J."],["dc.contributor.author","Gerlach, M."],["dc.contributor.author","Havemann-Reinecke, U."],["dc.contributor.author","Hefner, G."],["dc.contributor.author","Florio, V."],["dc.contributor.author","Kuzin, M."],["dc.contributor.author","Lieb, K."],["dc.contributor.author","Reis, M."],["dc.contributor.author","Riemer, T.G."],["dc.contributor.author","Seretti, A."],["dc.contributor.author","Schoretsanitis, G."],["dc.contributor.author","Zernig, G."],["dc.contributor.author","Gründer, G."],["dc.contributor.author","Hart, X. M."],["dc.date.accessioned","2022-09-01T09:50:18Z"],["dc.date.available","2022-09-01T09:50:18Z"],["dc.date.issued","2022"],["dc.identifier.doi","10.1055/s-0042-1747647"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/113674"],["dc.notes.intern","DOI-Import GROB-597"],["dc.publisher","Georg Thieme Verlag KG"],["dc.relation.conference","XIVth Symposium of the Task Force Therapeutic Drug Monitoring of\r\n the AGNP"],["dc.relation.eventend","2022-06-24"],["dc.relation.eventlocation","Mannheim, Germany"],["dc.relation.eventstart","2022-06-22"],["dc.title","Escitalopram: Drug monitoring for dose titration? Systematic\r\n literature review on the therapeutic and the dose-related reference\r\n range"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e17512"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","PLoS One"],["dc.bibliographiccitation.volume","6"],["dc.contributor.author","Reis, Micael"],["dc.contributor.author","Sousa-Guimarães, Sofia"],["dc.contributor.author","Vieira, Cristina P."],["dc.contributor.author","Sunkel, Cláudio E."],["dc.contributor.author","Vieira, Jorge"],["dc.date.accessioned","2020-06-29T07:14:33Z"],["dc.date.available","2020-06-29T07:14:33Z"],["dc.date.issued","2011"],["dc.description.abstract","Using a phylogenetic approach, the examination of 33 meiosis/meiosis-related genes in 12 Drosophila species, revealed nine independent gene duplications, involving the genes cav, mre11, meiS332, polo and mtrm. Evidence is provided that at least eight out of the nine gene duplicates are functional. Therefore, the rate at which Drosophila meiosis/meiosis-related genes are duplicated and retained is estimated to be 0.0012 per gene per million years, a value that is similar to the average for all Drosophila genes. It should be noted that by using a phylogenetic approach the confounding effect of concerted evolution, that is known to lead to overestimation of the duplication and retention rate, is avoided. This is an important issue, since even in our moderate size sample, evidence for long-term concerted evolution (lasting for more than 30 million years) was found for the meiS332 gene pair in species of the Drosophila subgenus. Most striking, in contrast to theoretical expectations, is the finding that genes that encode proteins that must follow a close stoichiometric balance, such as polo, mtrm and meiS332 have been found duplicated. The duplicated genes may be examples of gene neofunctionalization. It is speculated that meiosis duration may be a trait that is under selection in Drosophila and that it has different optimal values in different species."],["dc.identifier.doi","10.1371/journal.pone.0017512"],["dc.identifier.scopus","2-s2.0-79952523294"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/66762"],["dc.identifier.url","http://www.scopus.com/inward/record.url?eid=2-s2.0-79952523294&partnerID=MN8TOARS"],["dc.language.iso","en"],["dc.relation.issn","1932-6203"],["dc.title","Drosophila genes that affect meiosis duration are among the meiosis related genes that are more often found duplicated"],["dc.type","journal_article"],["dc.type.internalPublication","no"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1841"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","G3: Genes, Genomes, Genetics"],["dc.bibliographiccitation.lastpage","1851"],["dc.bibliographiccitation.volume","6"],["dc.contributor.author","Reis, Micael"],["dc.contributor.author","Silva, A. C."],["dc.contributor.author","Vieira, C. P."],["dc.contributor.author","Vieira, J."],["dc.date.accessioned","2020-06-25T10:18:44Z"],["dc.date.available","2020-06-25T10:18:44Z"],["dc.date.issued","2016"],["dc.description.abstract","Mucins have been implicated in many different biological processes, such as protection from mechanical damage, microorganisms, and toxic molecules, as well as providing a luminal scaffold during development. Nevertheless, it is conceivable that mucins have the potential to modulate food absorption as well, and thus contribute to the definition of several important phenotypic traits. Here we show that the Drosophila melanogaster Muc68E gene is 40- to 60-million-yr old, and is present in Drosophila species of the subgenus Sophophora only. The central repeat region of this gene is fast evolving, and shows evidence for repeated expansions/contractions. This and/or frequent gene conversion events lead to the homogenization of its repeats. The amino acid pattern P[ED][ED][ST][ST][ST] is found in the repeat region of Muc68E proteins from all Drosophila species studied, and can occur multiple times within a single conserved repeat block, and thus may have functional significance. Muc68E is a nonessential gene under laboratory conditions, but Muc68E mutant flies are smaller and lighter than controls at birth. However, at 4 d of age, Muc68E mutants are heavier, recover faster from chill-coma, and are more resistant to starvation than control flies, although they have the same percentage of lipids as controls. Mutant flies have enlarged abdominal size 1 d after chill-coma recovery, which is associated with higher lipid content. These results suggest that Muc68E has a role in metabolism modulation, food absorption, and/or feeding patterns in larvae and adults, and under normal and stress conditions. Such biological function is novel for mucin genes."],["dc.identifier.doi","10.1534/g3.116.029934"],["dc.identifier.pmid","27172221"],["dc.identifier.scopus","2-s2.0-84978388450"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/66746"],["dc.identifier.url","http://www.scopus.com/inward/record.url?eid=2-s2.0-84978388450&partnerID=MN8TOARS"],["dc.language.iso","en"],["dc.relation.eissn","2160-1836"],["dc.relation.issn","2160-1836"],["dc.title","The Drosophila melanogaster Muc68E mucin gene influences adult size, starvation tolerance, and cold recovery"],["dc.type","journal_article"],["dc.type.internalPublication","no"],["dspace.entity.type","Publication"]]