Moser, Norman

[["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Clinical Case Reports"],["dc.bibliographiccitation.volume","10"],["dc.contributor.author","Geisenhainer, Katharina"],["dc.contributor.author","Klenke, Daniela"],["dc.contributor.author","Moser, Norman"],["dc.contributor.author","Kurbad, Oliver"],["dc.contributor.author","Bremmer, Felix"],["dc.contributor.author","Kauffmann, Philipp"],["dc.contributor.author","Schliephake, H."],["dc.contributor.author","Brockmeyer, Phillipp"],["dc.date.accessioned","2022-02-01T10:32:02Z"],["dc.date.available","2022-02-01T10:32:02Z"],["dc.date.issued","2022"],["dc.description.sponsorship","Open-Access-Publikationsfonds 2022"],["dc.description.sponsorship","Open-Access-Publikationsfonds 2022"],["dc.identifier.doi","10.1002/ccr3.5268"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/99006"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-517"],["dc.relation.eissn","2050-0904"],["dc.relation.issn","2050-0904"],["dc.rights","CC BY 4.0"],["dc.rights.uri","http://creativecommons.org/licenses/by-nc/4.0/"],["dc.title","Desmoid fibromatosis in the pharyngeal wall: A case report and literature review"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1223"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Clinical Oral Investigations"],["dc.bibliographiccitation.lastpage","1234"],["dc.bibliographiccitation.volume","22"],["dc.contributor.author","Moser, Norman"],["dc.contributor.author","Goldstein, Jan"],["dc.contributor.author","Kauffmann, Philipp"],["dc.contributor.author","Epple, Matthias"],["dc.contributor.author","Schliephake, Henning"],["dc.date.accessioned","2018-06-25T07:45:51Z"],["dc.date.available","2018-06-25T07:45:51Z"],["dc.date.issued","2018-04"],["dc.description.abstract","(1) Objectives: The aim of the present study was to test the hypothesis that the ratio of angiogenic and osteogenic signaling affects ectopic bone formation when delivered in different amounts. (2) Materials and methods: Porous composite PDLLA/CaCO3 scaffolds were loaded with rhBMP2 and rhVEGF in different dosage combinations and implanted into the gluteal muscles of 120 adult male Wistar rats. Bone formation and expression of alkaline phosphatase and Runx2 were quantified by histomorphometry. Spatial distribution across the scaffolds was assessed by using a grid that discriminated between the periphery and center of the scaffolds. (3) Results: The evaluation showed that the combined delivery of bone morphogenetic protein BMP2 and VEGF in different dosage combinations did not enhance the overall quantity of ectopic bone formation compared to the delivery of BMP2 alone. The addition of VEGF generally upregulated Runx2 after 4 weeks, which may have retarded terminal osteogenic differentiation. However, slow combined delivery of 1.5–2.0 μg BMP2 combined with 50 ng VEGF165 over a period of 5 weeks supported a more even distribution of bone formation across the implanted scaffolds whereas higher amounts of VEGF did not elicit this effect. (4) Conclusions: The findings suggest that structural organization rather than the quantity of ectopic bone formation is affected by the dosage and the ratio of BMP2 and VEGF levels at the observed intervals. Clinical relevance The development of carriers for dual growth factor delivery has to take into account the necessity to carefully balance the ratio of growth release."],["dc.identifier.doi","10.1007/s00784-017-2202-3"],["dc.identifier.pmid","28936783"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/15134"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.eissn","1436-3771"],["dc.title","Experimental variation of the level and the ratio of angiogenic and osteogenic signaling affects the spatiotemporal expression of bone-specific markers and organization of bone formation in ectopic sites"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","347"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","International Journal of Oral and Maxillofacial Surgery"],["dc.bibliographiccitation.lastpage","354"],["dc.bibliographiccitation.volume","48"],["dc.contributor.author","Quast, A."],["dc.contributor.author","Santander, P."],["dc.contributor.author","Witt, D."],["dc.contributor.author","Damm, A."],["dc.contributor.author","Moser, N."],["dc.contributor.author","Schliephake, H."],["dc.contributor.author","Meyer-Marcotty, P."],["dc.date.accessioned","2020-12-10T14:24:37Z"],["dc.date.available","2020-12-10T14:24:37Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1016/j.ijom.2018.09.001"],["dc.identifier.issn","0901-5027"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/72307"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Traditional face-bow transfer versus three-dimensional virtual reconstruction in orthognathic surgery"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","201"],["dc.bibliographiccitation.issue","Pt A"],["dc.bibliographiccitation.journal","Journal of controlled release : official journal of the Controlled Release Society"],["dc.bibliographiccitation.lastpage","209"],["dc.bibliographiccitation.volume","220"],["dc.contributor.author","Lohse, N."],["dc.contributor.author","Moser, N."],["dc.contributor.author","Backhaus, S."],["dc.contributor.author","Annen, T."],["dc.contributor.author","Epple, M."],["dc.contributor.author","Schliephake, H."],["dc.date.accessioned","2018-06-25T07:52:25Z"],["dc.date.available","2018-06-25T07:52:25Z"],["dc.date.issued","2015"],["dc.description.abstract","The aim of the present study was to test the hypothesis that different amounts of vascular endothelial growth factor and bone morphogenic protein differentially affect bone formation when applied for repair of non-healing defects in the rat mandible. Porous composite PDLLA/CaCO3 carriers were fabricated as slow release carriers and loaded with rhBMP2 and rhVEGF165 in 10 different dosage combinations using gas foaming with supercritical carbon dioxide. They were implanted in non-healing defects of the mandibles of 132 adult Wistar rats with additional lateral augmentation. Bone formation was assessed both radiographically (bone volume) and by histomorphometry (bone density). The use of carriers with a ratio of delivery of VEGF/BMP between 0.7 and 1.2 was significantly related to the occurrence of significant increases in radiographic bone volume and/or histologic bone density compared to the use of carriers with a ratio of delivery of ≤ 0.5 when all intervals and all outcome parameters were considered. Moreover, simultaneous delivery at this ratio helped to \"save\" rhBMP2 as both bone volume and bone density after 13 weeks were reached/surpassed using half the dosage required for rhBMP2 alone. It is concluded, that the combined delivery of rhVEGF165 and rhBMP2 for repair of critical size mandibular defects can significantly enhance volume and density of bone formation over delivery of rhBMP2 alone. It appears from the present results that continuous simultaneous delivery of rhVEGF165 and rhBMP2 at a ratio of approximately 1 is favourable for the enhancement of bone formation."],["dc.identifier.doi","10.1016/j.jconrel.2015.10.032"],["dc.identifier.pmid","26485046"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/15136"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.eissn","1873-4995"],["dc.title","Continuous delivery of rhBMP2 and rhVEGF165 at a certain ratio enhances bone formation in mandibular defects over the delivery of rhBMP2 alone--An experimental study in rats"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1618"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery"],["dc.bibliographiccitation.lastpage","1629"],["dc.bibliographiccitation.volume","44"],["dc.contributor.author","Troeltzsch, Markus"],["dc.contributor.author","Troeltzsch, Matthias"],["dc.contributor.author","Kauffmann, Philipp"],["dc.contributor.author","Gruber, Rudolph"],["dc.contributor.author","Brockmeyer, Phillipp"],["dc.contributor.author","Moser, Norman"],["dc.contributor.author","Rau, Anna"],["dc.contributor.author","Schliephake, Henning"],["dc.date.accessioned","2018-06-25T07:48:54Z"],["dc.date.available","2018-06-25T07:48:54Z"],["dc.date.issued","2016-10"],["dc.description.abstract","To evaluate the efficacy of grafting materials in lateral and vertical ridge augmentations."],["dc.identifier.doi","10.1016/j.jcms.2016.07.028"],["dc.identifier.pmid","27622971"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/15135"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.eissn","1878-4119"],["dc.title","Clinical efficacy of grafting materials in alveolar ridge augmentation: A systematic review"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","162"],["dc.bibliographiccitation.journal","European Cells and Materials"],["dc.bibliographiccitation.lastpage","179"],["dc.bibliographiccitation.volume","34"],["dc.contributor.author","Moser, N"],["dc.contributor.author","Lohse, N"],["dc.contributor.author","Goldstein, J"],["dc.contributor.author","Kauffmann, P"],["dc.contributor.author","Sven, B"],["dc.contributor.author","Epple, M"],["dc.contributor.author","Schliephake, H"],["dc.contributor.authorgroup","Department of Oral and Maxillofacial Surgery, George-Augusta-University, Robert-Koch-Str. 40, 37075 Göttingen, Germany"],["dc.date.accessioned","2021-06-01T10:48:39Z"],["dc.date.available","2021-06-01T10:48:39Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.22203/eCM.v034a11"],["dc.identifier.pmid","28980278"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/17007"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/86006"],["dc.notes.intern","DOI-Import GROB-425"],["dc.notes.intern","Merged from goescholar"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Do we need retarded delivery of bone growth factors in facial bone repair? An experimental study in rats"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Clinical Oral Investigations"],["dc.contributor.author","Quast, Anja"],["dc.contributor.author","Santander, Petra"],["dc.contributor.author","Leding, Johanna"],["dc.contributor.author","Klenke, Daniela"],["dc.contributor.author","Moser, Norman"],["dc.contributor.author","Schliephake, Henning"],["dc.contributor.author","Meyer-Marcotty, Philipp"],["dc.date.accessioned","2021-04-14T08:30:47Z"],["dc.date.available","2021-04-14T08:30:47Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1007/s00784-020-03730-6"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/83373"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1436-3771"],["dc.relation.issn","1432-6981"],["dc.title","Orthodontic incisor decompensation in orthognathic therapy—success and efficiency in three dimensions"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","617"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","QUINTESSENCE INTERNATIONAL"],["dc.bibliographiccitation.lastpage","621"],["dc.bibliographiccitation.volume","47"],["dc.contributor.author","Santander, Petra"],["dc.contributor.author","Sievers, Denise"],["dc.contributor.author","Moser, Norman"],["dc.date.accessioned","2018-11-07T10:11:49Z"],["dc.date.available","2018-11-07T10:11:49Z"],["dc.date.issued","2016"],["dc.description.abstract","Non-restorative sleep has considerable consequences for daily life. A sleep disorder is recognized by symptoms such as daytime fatigue and performance or concentration disorders. Furthermore, it increases the risk of developing cardiovascular, metabolic, and neurologic diseases. The diagnosis and therapy of sleep disorders is not only in the sleep medicine doctor's hands. A multidisciplinary approach reflects the affected patients' choice. Dentists can make an important contribution, especially to the therapy of sleep-related breathing disorder."],["dc.identifier.doi","10.3290/j.qi.a36172"],["dc.identifier.isi","000383362000010"],["dc.identifier.pmid","27319815"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/40120"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Quintessence Publishing Co Inc"],["dc.relation.issn","1936-7163"],["dc.relation.issn","0033-6572"],["dc.title","Sleep-related breathing disorders and dentistry: What is the relationship?"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Head & Face Medicine"],["dc.bibliographiccitation.volume","16"],["dc.contributor.author","Santander, Petra"],["dc.contributor.author","Quast, Anja"],["dc.contributor.author","Olbrisch, Carolin"],["dc.contributor.author","Rose, Marius"],["dc.contributor.author","Moser, Norman"],["dc.contributor.author","Schliephake, Henning"],["dc.contributor.author","Meyer-Marcotty, Philipp"],["dc.date.accessioned","2021-04-14T08:32:08Z"],["dc.date.available","2021-04-14T08:32:08Z"],["dc.date.issued","2020"],["dc.description.sponsorship","Open-Access-Publikationsfonds 2021"],["dc.identifier.doi","10.1186/s13005-020-00245-z"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/17690"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/83821"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.notes.intern","Merged from goescholar"],["dc.relation.eissn","1746-160X"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Comprehensive 3D analysis of condylar morphology in adults with different skeletal patterns – a cross-sectional study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","668"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","Oral Oncology"],["dc.bibliographiccitation.lastpage","673"],["dc.bibliographiccitation.volume","51"],["dc.contributor.author","Kramer, Franz-Josef"],["dc.contributor.author","Böhrnsen, Florian"],["dc.contributor.author","Moser, Norman"],["dc.contributor.author","Schliephake, Henning"],["dc.date.accessioned","2018-06-26T06:55:52Z"],["dc.date.available","2018-06-26T06:55:52Z"],["dc.date.issued","2015"],["dc.description.abstract","The submental island flap has become increasingly popular in the treatment of intraoral defects following tumor ablation. However, there was concern that the elevation of the pedicled flap might interfere with the efficiency of level I-lymph node dissection and decrease the oncologic prognosis of the patients."],["dc.identifier.doi","10.1016/j.oraloncology.2015.03.011"],["dc.identifier.pmid","25962940"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/15147"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.eissn","1879-0593"],["dc.title","The submental island flap for the treatment of intraoral tumor-related defects: No effect on recurrence rates"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]