Gross, Uwe

[["dc.bibliographiccitation.firstpage","728"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz"],["dc.bibliographiccitation.lastpage","734"],["dc.bibliographiccitation.volume","54"],["dc.contributor.author","Alter, T."],["dc.contributor.author","Bereswill, S."],["dc.contributor.author","Gluender, G."],["dc.contributor.author","Haag, L.-M."],["dc.contributor.author","Haenel, I."],["dc.contributor.author","Heimesaat, Markus M."],["dc.contributor.author","Lugert, Raimond"],["dc.contributor.author","Rautenschlein, Silke"],["dc.contributor.author","Weber, R. M."],["dc.contributor.author","Zautner, Andreas Erich"],["dc.contributor.author","Gross, U."],["dc.date.accessioned","2018-11-07T08:55:46Z"],["dc.date.available","2018-11-07T08:55:46Z"],["dc.date.issued","2011"],["dc.description.abstract","Over the last few years, infections with Campylobacter have significantly increased in Europe and Germany and these bacteria have even surpassed Salmonella as the most prevalent bacteria, causing gastroenteritis. Especially contamination during the handling and consumption of meat products seems to be the most important risk factor which plays a prominent role for transmission to man. In addition, contact with pets and other animals, drinking raw or improperly pasteurized milk, and the tenacity of Campylobacter in different environments, especially water, have also to be considered for an adequate risk assessment. Besides gastroenteritis, arthralgia, and Guillain-Barre syndrome are important clinical complications of Campylobacter infections in man. At the same time, it is mostly unclear why the course of infection in man and in reservoir animals differs significantly, especially as only a few classical bacterial virulence factors have been identified so far. For these reasons, the development of efficient prevention strategies is of utmost importance in order to control campylobacteriosis."],["dc.identifier.doi","10.1007/s00103-011-1289-y"],["dc.identifier.isi","000292038500010"],["dc.identifier.pmid","21626378"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/22983"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","1436-9990"],["dc.title","Campylobacteriosis of man. Livestock as reservoir for Campylobacter species"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","91"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Journal of Food Safety and Food Quality"],["dc.bibliographiccitation.lastpage","101"],["dc.bibliographiccitation.volume","61"],["dc.contributor.author","Zautner, Andreas Erich"],["dc.contributor.author","Herrmann, Sahra"],["dc.contributor.author","Gross, Uwe"],["dc.date.accessioned","2018-11-07T08:43:22Z"],["dc.date.available","2018-11-07T08:43:22Z"],["dc.date.issued","2010"],["dc.description.abstract","In recent years Campylobacter jejuni replaced Salmonella spp. as the most common bacterial cause of food-borne gastroenteritis worldwide. Noticeable is the fact that no classical enterotoxins are known for C. jejuni. The sequencing of the complete genome revealed that C. jejuni possesses one single trimeric cytotoxin, called cytolethal distending toxin (CdtABC). Other previously suspected toxins could not be confirmed by sequence analysis. However, a number of alternative virulence-associated factors have been identified so far. The multidrug efflux pump CmeABC faciliates, by \"neutralization\" of bile salts, the survival of C. jejuni in the avian as well as in the human intestine. Furthermore it is responsible for resistance to heavy metal ions and to certain antibiotics. The flagellum of C. jejuni mediates not only the targeted motility directed by three families of chemo- and aerotaxis receptors. A homologue of a type-III-secretion-system integrated in the flagellar apparatus is functionally involved in the cell-invasion process. Thus, a whole group of proteins termed Campylobacter invasion antigens (Cia) is injected into the host cell via the flagellar transport mechanism during the process of host cell invasion. Further pathogenicity-associated determinants are the polysaccharide capsule and specific glycosylation of the lipooligosaccharide (LOS). It has been shown that C. jejuni strains with sialylation of the lipooligosaccharide display increased invasiveness. These strains are also responsible for the development of the Guillain-Barre-syndrome, through molecular mimicry with gangliosides of the central nervous system. In the past, many colonization-related factors have been identified with the help of transposon-induced mutagenesis and chicken colonization models. Using this and other modern molecular biology methods, combined with appropriate animal models such as gnotobiotic mice in which symptomatic campylobacteriosis can be established, it is hoped to identify additional virulence-associated factors."],["dc.identifier.doi","10.2376/0003-925X-61-91"],["dc.identifier.isi","000280167900003"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/19946"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","M H Schaper Gmbh Co Kg"],["dc.relation.issn","0003-925X"],["dc.title","Campylobacter jejuni - The Search for virulence-associated factors"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Mycoses"],["dc.bibliographiccitation.volume","55"],["dc.contributor.author","Bader, Oliver"],["dc.contributor.author","Schwarz, A."],["dc.contributor.author","Kraneveld, Eefje A."],["dc.contributor.author","Tangwattanachuleeporn, Marut"],["dc.contributor.author","Schmidt, P."],["dc.contributor.author","Jacobsen, Mette D."],["dc.contributor.author","Gross, U."],["dc.contributor.author","de Groot, Piet W. J."],["dc.contributor.author","Weig, Michael S."],["dc.date.accessioned","2018-11-07T09:09:43Z"],["dc.date.available","2018-11-07T09:09:43Z"],["dc.date.issued","2012"],["dc.format.extent","143"],["dc.identifier.isi","000305069800445"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/26326"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.issn","0933-7407"],["dc.title","Karyotypic and phenotypic plasticity of the Candida glabrata strain CBS138/ATCC2001"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","11215"],["dc.bibliographiccitation.issue","17"],["dc.bibliographiccitation.journal","Analytical Chemistry"],["dc.bibliographiccitation.lastpage","11222"],["dc.bibliographiccitation.volume","91"],["dc.contributor.author","Garg, Monika"],["dc.contributor.author","Stern, Daniel"],["dc.contributor.author","Groß, Uwe"],["dc.contributor.author","Seeberger, Peter H."],["dc.contributor.author","Seeber, Frank"],["dc.contributor.author","Varón Silva, Daniel"],["dc.date.accessioned","2020-12-10T15:22:30Z"],["dc.date.available","2020-12-10T15:22:30Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1021/acs.analchem.9b02154"],["dc.identifier.eissn","1520-6882"],["dc.identifier.issn","0003-2700"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/73425"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Detection of Anti- Toxoplasma gondii Antibodies in Human Sera Using Synthetic Glycosylphosphatidylinositol Glycans on a Bead-Based Multiplex Assay"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","517"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Antimicrobial Agents and Chemotherapy"],["dc.bibliographiccitation.lastpage","521"],["dc.bibliographiccitation.volume","54"],["dc.contributor.author","Bajohr, Lara Liv"],["dc.contributor.author","Ma, Ling"],["dc.contributor.author","Platte, Christian"],["dc.contributor.author","Liesenfeld, Oliver"],["dc.contributor.author","Tietze, Lutz Friedjan"],["dc.contributor.author","Gross, Uwe"],["dc.contributor.author","Bohne, Wolfgang"],["dc.date.accessioned","2018-11-07T08:47:00Z"],["dc.date.available","2018-11-07T08:47:00Z"],["dc.date.issued","2010"],["dc.description.abstract","1-Hydroxy-2-dodecyl-4(1H) quinolone (HDQ) was recently identified as a Toxoplasma gondii inhibitor. We describe here two novel 1-hydroxyquinolones, which displayed 50% inhibitory concentrations 10- and 5-fold lower than that of HDQ. In a mouse model of acute toxoplasmosis, these two compounds and HDQ reduced the percentages of infected peritoneal cells and decreased the parasite loads in lungs and livers. Compound B showed a tendency toward lowering parasite loads in brains in a mouse model of toxoplasmic encephalitis."],["dc.identifier.doi","10.1128/AAC.01001-09"],["dc.identifier.isi","000272931200069"],["dc.identifier.pmid","19884369"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/20837"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Soc Microbiology"],["dc.relation.issn","0066-4804"],["dc.title","In Vitro and In Vivo Activities of 1-Hydroxy-2-Alkyl-4(1H)Quinolone Derivatives against Toxoplasma gondii"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1035"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","Clinical Infectious Diseases"],["dc.bibliographiccitation.lastpage","1036"],["dc.bibliographiccitation.volume","54"],["dc.contributor.author","Bader, Oliver"],["dc.contributor.author","Weig, Michael S."],["dc.contributor.author","Gross, Uwe"],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Mempel, Martin"],["dc.contributor.author","Buhl, Timo"],["dc.date.accessioned","2018-11-07T09:11:58Z"],["dc.date.available","2018-11-07T09:11:58Z"],["dc.date.issued","2012"],["dc.identifier.doi","10.1093/cid/cir943"],["dc.identifier.isi","000301296200029"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/26841"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press Inc"],["dc.relation.issn","1058-4838"],["dc.title","A 32-Year-Old Man With Ulcerative Mucositis, Skin Lesions, and Nail Dystrophy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.subtype","letter_note"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Frontiers in Microbiology"],["dc.bibliographiccitation.volume","13"],["dc.contributor.author","Taverne-Ghadwal, Liliane"],["dc.contributor.author","Kuhns, Martin"],["dc.contributor.author","Buhl, Timo"],["dc.contributor.author","Schulze, Marco H."],["dc.contributor.author","Mbaitolum, Weina Joseph"],["dc.contributor.author","Kersch, Lydia"],["dc.contributor.author","Weig, Michael"],["dc.contributor.author","Bader, Oliver"],["dc.contributor.author","Groß, U."],["dc.date.accessioned","2022-04-01T10:00:45Z"],["dc.date.available","2022-04-01T10:00:45Z"],["dc.date.issued","2022"],["dc.description.abstract","Oral candidiasis remains a common problem in HIV-infected individuals, especially in sub-Saharan Africa. Here, we performed the first study in Chad on the prevalence of oral yeasts carriage and oral candidiasis in HIV-positive subjects from southern Chad and analyzed the influence of HAART, CD4 + T-cell numbers, and antimycotics in 589 patients. These patients were recruited from a specialized medical center for HIV patients in Sarh and from a rural medical health dispensary in the vicinity, including a total of 384 HIV-positive and 205 HIV-negative individuals. Yeasts obtained from oral specimen were identified by MALDI-TOF MS and their antifungal susceptibility profiles determined. The overall prevalence of yeast colonization and symptomatic oral candidiasis in HIV-infected patients was 25.1%. The prevalence of oral candidiasis was higher in untreated than in HAART-treated HIV-positive patients (16% vs. 2%; p  < 0.01). Oral candidiasis was furthermore associated with high fungal burdens of Candida albicans and a CD4 + T-cell number <200/μl. A shift toward non -albicans Candida species was observed under nucleoside-based HAART therapy. Azole antifungal drug resistance was only observed for the intrinsically resistant species Candida krusei and Candida glabrata . Prevalence of oral candidiasis in the studied area was very low. The species distribution was similar to other countries around the world, with C. albicans being dominant. Candida dubliniensis was not isolated. Nucleoside-based HAART therapy significantly reduced oral colonization as well as occurrence of oral candidiasis caused by C. albicans and led to a species shift toward non- albicans species. Antifungal resistance was not yet a concern in Chad."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2022"],["dc.identifier.doi","10.3389/fmicb.2022.844069"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/105503"],["dc.notes.intern","DOI-Import GROB-530"],["dc.relation.eissn","1664-302X"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0/"],["dc.title","Epidemiology and Prevalence of Oral Candidiasis in HIV Patients From Chad in the Post-HAART Era"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","916"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Emerging Infectious Diseases"],["dc.bibliographiccitation.lastpage","919"],["dc.bibliographiccitation.volume","24"],["dc.contributor.author","Janssen, Hauke"],["dc.contributor.author","Janssen, Iryna"],["dc.contributor.author","Cooper, Paul"],["dc.contributor.author","Kainyah, Clemens"],["dc.contributor.author","Pellio, Theresia"],["dc.contributor.author","Quintel, Michael"],["dc.contributor.author","Monnheimer, Mathieu"],["dc.contributor.author","Groß, Uwe"],["dc.contributor.author","Schulze, Marco H."],["dc.date.accessioned","2020-12-10T18:44:07Z"],["dc.date.available","2020-12-10T18:44:07Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.3201/eid2405.171506"],["dc.identifier.eissn","1080-6059"],["dc.identifier.issn","1080-6040"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78338"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Antimicrobial-Resistant Bacteria in Infected Wounds, Ghana, 20141"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","105"],["dc.bibliographiccitation.journal","International Journal of Medical Microbiology"],["dc.bibliographiccitation.lastpage","106"],["dc.bibliographiccitation.volume","293"],["dc.contributor.author","Keller, Peter"],["dc.contributor.author","Goebel, S."],["dc.contributor.author","Fischer, S. F."],["dc.contributor.author","Hacker, G."],["dc.contributor.author","Gross, U."],["dc.contributor.author","Luder, C. G. K."],["dc.date.accessioned","2018-11-07T10:50:40Z"],["dc.date.available","2018-11-07T10:50:40Z"],["dc.date.issued","2004"],["dc.identifier.isi","000222589900164"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/48707"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Urban & Fischer Verlag"],["dc.publisher.place","Jena"],["dc.relation.conference","21st Congress of the German-Society-of-Parasitology"],["dc.relation.eventlocation","Univ Wurzburg, Wurzburg, GERMANY"],["dc.relation.issn","1438-4221"],["dc.title","Inhibition of caspase activity by Toxoplasma gondii in a cell-free system indicates novel mechanisms of interference with host cell apoptosis"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Tropical Medicine & International Health"],["dc.bibliographiccitation.volume","20"],["dc.contributor.author","Deutschmann, S."],["dc.contributor.author","Bohne, Wolfgang"],["dc.contributor.author","Mujuni, F."],["dc.contributor.author","Kalluvya, S."],["dc.contributor.author","Mshana, Stephen E."],["dc.contributor.author","Gross, U."],["dc.contributor.author","Mueller, A."],["dc.date.accessioned","2018-11-07T09:52:27Z"],["dc.date.available","2018-11-07T09:52:27Z"],["dc.date.issued","2015"],["dc.format.extent","287"],["dc.identifier.isi","000360758801298"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/36128"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.issn","1365-3156"],["dc.relation.issn","1360-2276"],["dc.title","Low prevalence of Neisseria gonorrhoeae infections and no evidence of resistance against third generation cephalosporins in a cohort of HIV positive patients from a tertiary hospital in Tanzania"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]