Now showing 1 - 10 of 94
  • 2021-09-16Journal Article Research Paper
    [["dc.bibliographiccitation.firstpage","798"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","BMC Musculoskeletal Disorders"],["dc.bibliographiccitation.volume","22"],["dc.contributor.author","Prediger, Barbara"],["dc.contributor.author","Tjardes, Thorsten"],["dc.contributor.author","Probst, Christian"],["dc.contributor.author","Heu-Parvaresch, Anahieta"],["dc.contributor.author","Glatt, Angelina"],["dc.contributor.author","Dos Anjos, Dominique Rodil"],["dc.contributor.author","Bouillon, Bertil"],["dc.contributor.author","Mathes, Tim"],["dc.date.accessioned","2021-10-27T14:32:36Z"],["dc.date.available","2021-10-27T14:32:36Z"],["dc.date.issued","2021-09-16"],["dc.description.abstract","We assessed predictive factors of patients with fractures of the lower extremities caused by trauma. We examined which factors are associated with an increased risk of failure. Furthermore, the predictive factors were set into context with other long-term outcomes, concrete pain and physical functioning."],["dc.identifier.doi","10.1186/s12891-021-04688-6"],["dc.identifier.pmid","34530793"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/92140"],["dc.language.iso","en"],["dc.relation.eissn","1471-2474"],["dc.title","Factors predicting failure of internal fixations of fractures of the lower limbs: a prospective cohort study"],["dc.type","journal_article"],["dc.type.internalPublication","no"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]
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  • 2021-06-11Journal Article Research Paper
    [["dc.bibliographiccitation.firstpage","403"],["dc.bibliographiccitation.issue","23"],["dc.bibliographiccitation.journal","Deutsches Ärzteblatt international"],["dc.bibliographiccitation.lastpage","404"],["dc.bibliographiccitation.volume","118"],["dc.contributor.author","Schwarz, Sarah Bettina"],["dc.contributor.author","Wollsching-Strobel, Maximilian"],["dc.contributor.author","Majorski, Daniel Sebastian"],["dc.contributor.author","Magnet, Friederike Sophie"],["dc.contributor.author","Mathes, Tim"],["dc.contributor.author","Windisch, Wolfram"],["dc.date.accessioned","2021-10-27T14:31:38Z"],["dc.date.available","2021-10-27T14:31:38Z"],["dc.date.issued","2021-06-11"],["dc.identifier.doi","10.3238/arztebl.m2021.0193"],["dc.identifier.pmid","34304756"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/92125"],["dc.language.iso","en"],["dc.relation.issn","1866-0452"],["dc.title","The Development of Inpatient Initiation and Follow-up of Home Mechanical Ventilation in Germany"],["dc.type","journal_article"],["dc.type.internalPublication","no"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]
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  • 2014-09Journal Article Research Paper
    [["dc.bibliographiccitation.firstpage","187"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Research Synthesis Methods"],["dc.bibliographiccitation.lastpage","199"],["dc.bibliographiccitation.volume","5"],["dc.contributor.author","Pieper, Dawid"],["dc.contributor.author","Antoine, Sunya-Lee"],["dc.contributor.author","Morfeld, Jana-Carina"],["dc.contributor.author","Mathes, Tim"],["dc.contributor.author","Eikermann, Michaela"],["dc.date.accessioned","2021-10-27T09:52:42Z"],["dc.date.available","2021-10-27T09:52:42Z"],["dc.date.issued","2014-09"],["dc.description.abstract","Overviews search for reviews rather than for primary studies. They might have the potential to support decision making within a shorter time frame by reducing production time. We aimed to summarize available instructions for authors intending to conduct overviews as well as the currently applied methodology of overviews in international Health Technology Assessment (HTA) agencies."],["dc.identifier.doi","10.1002/jrsm.1107"],["dc.identifier.pmid","26052845"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/91410"],["dc.language.iso","en"],["dc.relation.eissn","1759-2887"],["dc.relation.issn","1759-2879"],["dc.title","Methodological approaches in conducting overviews: current state in HTA agencies"],["dc.type","journal_article"],["dc.type.internalPublication","no"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]
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  • 2022Journal Article
    [["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","BMC Medical Research Methodology"],["dc.bibliographiccitation.volume","22"],["dc.contributor.author","Helbach, Jasmin"],["dc.contributor.author","Pieper, Dawid"],["dc.contributor.author","Mathes, Tim"],["dc.contributor.author","Rombey, Tanja"],["dc.contributor.author","Zeeb, Hajo"],["dc.contributor.author","Allers, Katharina"],["dc.contributor.author","Hoffmann, Falk"],["dc.date.accessioned","2022-09-01T09:50:54Z"],["dc.date.available","2022-09-01T09:50:54Z"],["dc.date.issued","2022"],["dc.description.abstract","Abstract\n \n Background\n Restrictions in systematic reviews (SRs) can lead to bias and may affect conclusions. Therefore, it is important to report whether and which restrictions were used. This study aims to examine the use of restrictions regarding language, publication period, and study type, as well as the transparency of reporting in SRs of effectiveness.\n \n \n Methods\n A retrospective observational study was conducted with a random sample of 535 SRs of effectiveness indexed in PubMed between 2000 and 2019. The use of restrictions and their reporting were analysed using descriptive statistics.\n \n \n Results\n Of the total 535 SRs included, four out of every ten (41.3%) lacked information on at least one of the three restrictions considered (language, publication period, or study type). Overall, 14.6% of SRs did not provide information on restrictions regarding publication period, 19.1% regarding study type, and 18.3% regarding language. Of all included SRs, language was restricted in 46.4%, and in more than half of the SRs with restricted language (130/248), it was unclear whether the restriction was applied during either the search or the screening process, or both. The restrictions were justified for publication period in 22.2% of the respective SRs (33/149), study type in 6.5% (28/433), and language in 3.2% (8/248). Differences in reporting were found between countries as well as between Cochrane and non-Cochrane reviews.\n \n \n Conclusions\n This study suggests that there is a lack of transparency in reporting on restrictions in SRs. Authors as well as editors and reviewers should be encouraged to improve the reporting and justification of restrictions to increase the transparency of SRs."],["dc.identifier.doi","10.1186/s12874-022-01710-w"],["dc.identifier.pii","1710"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/113830"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-597"],["dc.relation.eissn","1471-2288"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Restrictions and their reporting in systematic reviews of effectiveness: an observational study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2022Journal Article
    [["dc.bibliographiccitation.firstpage","e220625"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","JAMA Network Open"],["dc.bibliographiccitation.volume","5"],["dc.contributor.author","Karl, Vivien"],["dc.contributor.author","Thorn, Sophie"],["dc.contributor.author","Mathes, Tim"],["dc.contributor.author","Hess, Simone"],["dc.contributor.author","Maegele, Marc"],["dc.date.accessioned","2022-04-01T10:01:20Z"],["dc.date.available","2022-04-01T10:01:20Z"],["dc.date.issued","2022"],["dc.identifier.doi","10.1001/jamanetworkopen.2022.0625"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/105656"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-530"],["dc.relation.eissn","2574-3805"],["dc.title","Association of Tranexamic Acid Administration With Mortality and Thromboembolic Events in Patients With Traumatic Injury"],["dc.title.alternative","A Systematic Review and Meta-analysis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2013-05Journal Article Research Paper
    [["dc.bibliographiccitation.firstpage","1015"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Journal of the American College of Surgeons"],["dc.bibliographiccitation.lastpage","1025"],["dc.bibliographiccitation.volume","216"],["dc.contributor.author","Pieper, Dawid"],["dc.contributor.author","Mathes, Tim"],["dc.contributor.author","Neugebauer, Edmund"],["dc.contributor.author","Eikermann, Michaela"],["dc.date.accessioned","2021-10-27T09:53:27Z"],["dc.date.available","2021-10-27T09:53:27Z"],["dc.date.issued","2013-05"],["dc.identifier.doi","10.1016/j.jamcollsurg.2012.12.049"],["dc.identifier.pmid","23528183"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/91420"],["dc.language.iso","en"],["dc.relation.eissn","1879-1190"],["dc.relation.issn","1072-7515"],["dc.title","State of evidence on the relationship between high-volume hospitals and outcomes in surgery: a systematic review of systematic reviews"],["dc.type","journal_article"],["dc.type.internalPublication","no"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]
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  • 2018-09Journal Article Research Paper
    [["dc.bibliographiccitation.firstpage","366"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Research Synthesis Methods"],["dc.bibliographiccitation.lastpage","381"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Mathes, Tim"],["dc.contributor.author","Kuss, Oliver"],["dc.date.accessioned","2021-10-27T09:52:50Z"],["dc.date.available","2021-10-27T09:52:50Z"],["dc.date.issued","2018-09"],["dc.description.abstract","Meta-analyses often include only a small number of studies (≤5). Estimating between-study heterogeneity is difficult in this situation. An inaccurate estimation of heterogeneity can result in biased effect estimates and too narrow confidence intervals. The beta-binominal model has shown good statistical properties for meta-analysis of sparse data. We compare the beta-binominal model with different inverse variance random (eg, DerSimonian-Laird, modified Hartung-Knapp, and Paule-Mandel) and fixed effects methods (Mantel-Haenszel and Peto) in a simulation study. The underlying true parameters were obtained from empirical data of actually performed meta-analyses to best mirror real-life situations. We show that valid methods for meta-analysis of a small number of studies are available. In fixed effects situations, the Mantel-Haenszel and Peto methods performed best. In random effects situations, the beta-binominal model performed best for meta-analysis of few studies considering the balance between coverage probability and power. We recommended the beta-binominal model for practical application. If very strong evidence is needed, using the Paule-Mandel heterogeneity variance estimator combined with modified Hartung-Knapp confidence intervals might be useful to confirm the results. Notable most inverse variance random effects models showed unsatisfactory statistical properties also if more studies (10-50) were included in the meta-analysis."],["dc.identifier.doi","10.1002/jrsm.1296"],["dc.identifier.pmid","29573180"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/91412"],["dc.language.iso","en"],["dc.relation.eissn","1759-2887"],["dc.relation.issn","1759-2879"],["dc.title","A comparison of methods for meta-analysis of a small number of studies with binary outcomes"],["dc.type","journal_article"],["dc.type.internalPublication","no"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]
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  • 2022Journal Article
    [["dc.bibliographiccitation.firstpage","1"],["dc.bibliographiccitation.journal","Respiration"],["dc.bibliographiccitation.lastpage","9"],["dc.contributor.author","Wollsching-Strobel, Maximilian"],["dc.contributor.author","Butt, Uta"],["dc.contributor.author","Majorski, Daniel Sebastian"],["dc.contributor.author","Mathes, Tim"],["dc.contributor.author","Magnet, Friederike Sophie"],["dc.contributor.author","Berger, Melanie Patricia"],["dc.contributor.author","Schwarz, Sarah Bettina"],["dc.contributor.author","Windisch, Wolfram"],["dc.date.accessioned","2022-07-01T07:35:19Z"],["dc.date.available","2022-07-01T07:35:19Z"],["dc.date.issued","2022"],["dc.description.abstract","Background/Objective: To assess whether and how the use of scientifically established Web-based training videos for teaching correct inhalation technique in patients with chronic airway diseases has become accepted among the wider population. Methods: The viewing trends of 141 freely available YouTube videos (full playing time, 01:31–04:37 min:s) provided by the German Respiratory League, covering a broad range of internationally prescribed devices, were analyzed over a 10-year period. Specific emphasis was placed both on German and international videos. Results: The total number of views was 3,350,678. Non-German videos (English, Russian, Turkish, Greek, Arabic, Farsi, and Slovakian) accounted for 23.2% of the views. The number of views steadily increased between 2011 and 2020 with a mean annual increase of 54.0% (range 24.5/119.9%) compared to the respective previous year. By 2020, the incidence of views per 100,000 German inhabitants was 725 for German videos only and 1,030 for all videos. In terms of the annual trend, there were two peak viewing periods, namely in spring and late fall, while the lowest amount of views occurred in summer. Conclusion: This study highlights the rising impact of Web-based training videos used for teaching the correct use of inhalation devices, with a steady increase in the number of annual views and a clear seasonal peaking of views in spring and late fall."],["dc.identifier.doi","10.1159/000524712"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/112137"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-581"],["dc.relation.eissn","1423-0356"],["dc.relation.issn","0025-7931"],["dc.title","Evolution of Web-Based Training Videos Provided by the German Respiratory League for the Correct Inhalation Technique"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2013-07Journal Article Research Paper
    [["dc.bibliographiccitation.firstpage","227"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","International Journal of Technology Assessment in Health Care"],["dc.bibliographiccitation.lastpage","233"],["dc.bibliographiccitation.volume","29"],["dc.contributor.author","Mathes, Tim"],["dc.contributor.author","Pieper, Dawid"],["dc.contributor.author","Antoine, Sunya-Lee"],["dc.contributor.author","Eikermann, Michaela"],["dc.date.accessioned","2021-10-27T09:54:33Z"],["dc.date.available","2021-10-27T09:54:33Z"],["dc.date.issued","2013-07"],["dc.description.abstract","The objective of this systematic review was to evaluate the cost-effectiveness of interventions aiming to increase the adherence to highly active antiretroviral therapy (HAART) in HIV-infected patients in developed countries (WHO stratum A)."],["dc.identifier.doi","10.1017/S0266462313000317"],["dc.identifier.pmid","23759359"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/91437"],["dc.language.iso","en"],["dc.relation.eissn","1471-6348"],["dc.relation.issn","0266-4623"],["dc.title","Cost-effectiveness of adherence interventions for highly active antiretroviral therapy: a systematic review"],["dc.type","journal_article"],["dc.type.internalPublication","no"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]
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  • 2017-07-17Journal Article Research Paper
    [["dc.bibliographiccitation.firstpage","107"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","BMC Medical Research Methodology"],["dc.bibliographiccitation.volume","17"],["dc.contributor.author","Mathes, Tim"],["dc.contributor.author","Pieper, Dawid"],["dc.date.accessioned","2021-10-27T14:32:15Z"],["dc.date.available","2021-10-27T14:32:15Z"],["dc.date.issued","2017-07-17"],["dc.description.abstract","Distinguishing cohort studies from case series is difficult.We propose a conceptualization of cohort studies in systematic reviews of comparative studies. The main aim of this conceptualization is to clarify the distinction between cohort studies and case series. We discuss the potential impact of the proposed conceptualization on the body of evidence and workload.All studies with exposure-based sampling gather multiple exposures (with at least two different exposures or levels of exposure) and enable calculation of relative risks that should be considered cohort studies in systematic reviews, including non-randomized studies. The term \"enables/can\" means that a predefined analytic comparison is not a prerequisite (i.e., the absolute risks per group and/or a risk ratio are provided). Instead, all studies for which sufficient data are available for reanalysis to compare different exposures (e.g., sufficient data in the publication) are classified as cohort studies.There are possibly large numbers of studies without a comparison for the exposure of interest but that do provide the necessary data to calculate effect measures for a comparison. Consequently, more studies could be included in a systematic review. Therefore, on the one hand, the outlined approach can increase the confidence in effect estimates and the strengths of conclusions. On the other hand, the workload would increase (e.g., additional data extraction and risk of bias assessment, as well as reanalyses)."],["dc.identifier.doi","10.1186/s12874-017-0391-8"],["dc.identifier.pmid","28716005"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/92134"],["dc.language.iso","en"],["dc.relation.issn","1471-2288"],["dc.title","Clarifying the distinction between case series and cohort studies in systematic reviews of comparative studies: potential impact on body of evidence and workload"],["dc.type","journal_article"],["dc.type.internalPublication","no"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]
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