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Behrens, Christoph
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Behrens, Christoph
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Behrens, Christoph
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Behrens, C.
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2017Journal Article [["dc.bibliographiccitation.firstpage","A31"],["dc.bibliographiccitation.journal","Astronomy and Astrophysics"],["dc.bibliographiccitation.volume","614"],["dc.contributor.author","Behrens, Christoph"],["dc.contributor.author","Byrohl, Chris"],["dc.contributor.author","Saito, Shun"],["dc.contributor.author","Niemeyer, Jens C."],["dc.date.accessioned","2020-07-01T08:28:01Z"],["dc.date.available","2020-07-01T08:28:01Z"],["dc.date.issued","2017"],["dc.description.abstract","Lyman-$\\alpha$ emitters (LAEs) are a promising probe of the large-scale structure at high redshift, \\gtrsim 2$. In particular, the Hobby-Eberly Telescope Dark Energy Experiment aims at observing LAEs at 1.9 $<z<$ 3.5 to measure the Baryon Acoustic Oscillation (BAO) scale and the Redshift-Space Distortion (RSD). However, Zheng et al. (2011) pointed out that the complicated radiative transfer (RT) of the resonant Lyman-$\\alpha$ emission line generates an anisotropic selection bias in the LAE clustering on large scales, \\gtrsim 10$ Mpc. This effect could potentially induce a systematic error in the BAO and RSD measurements. Also, Croft et al. (2016) claims an observational evidence of the effect in the Lyman-$\\alpha$ intensity map, albeit statistically insignificant. We aim at quantifying the impact of the Lyman-$\\alpha$ RT on the large-scale galaxy clustering in detail. For this purpose, we study the correlations between the large-scale environment and the ratio of an apparent Lyman-$\\alpha$ luminosity to an intrinsic one, which we call the 'observed fraction', at <z<6$. We apply our Lyman-$\\alpha$ RT code by post-processing the full Illustris simulations. We simply assume that the intrinsic luminosity of the Lyman-$\\alpha$ emission is proportional to the star formation rate of galaxies in Illustris, yielding a sufficiently large sample of LAEs to measure the anisotropic selection bias. We find little correlations between large-scale environment and the observed fraction induced by the RT, and hence a smaller anisotropic selection bias than what was claimed by Zheng et al. (2011). We argue that the anisotropy was overestimated in the previous work due to the insufficient spatial resolution: it is important to keep the resolution such that it resolves the high density region down to the scale of the interstellar medium, $\\sim1$ physical kpc. (abridged)"],["dc.identifier.arxiv","1710.06171v2"],["dc.identifier.doi","10.1051/0004-6361/201731783"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/66816"],["dc.language.iso","en"],["dc.relation.eissn","1432-0746"],["dc.relation.issn","0004-6361"],["dc.title","The impact of Lyman-$α$ radiative transfer on large-scale clustering in the Illustris simulation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]Details DOI2021Journal Article [["dc.bibliographiccitation.firstpage","2349"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Monthly Notices of the Royal Astronomical Society"],["dc.bibliographiccitation.lastpage","2368"],["dc.bibliographiccitation.volume","503"],["dc.contributor.author","Di Mascia, F"],["dc.contributor.author","Gallerani, S"],["dc.contributor.author","Behrens, C"],["dc.contributor.author","Pallottini, A"],["dc.contributor.author","Carniani, S"],["dc.contributor.author","Ferrara, A"],["dc.contributor.author","Barai, P"],["dc.contributor.author","Vito, F"],["dc.contributor.author","Zana, T"],["dc.date.accessioned","2021-07-05T14:57:33Z"],["dc.date.available","2021-07-05T14:57:33Z"],["dc.date.issued","2021"],["dc.description.abstract","ABSTRACT We investigate the infrared (IR) emission of high-redshift (z ∼ 6), highly star-forming (${{\\rm SFR}\\gt 100\\,{\\rm M}_{\\odot }\\, {\\rm yr}^{-1}}$) galaxies, with/without active galactic nuclei (AGN), using a suite of cosmological simulations featuring dust radiative transfer. Synthetic spectral energy distributions (SEDs) are used to quantify the relative contribution of stars/AGN to dust heating. In dusty (Md ≳ 3 × 107 M⊙) galaxies, ≳50–90 per cent of the ultraviolet (UV) radiation is obscured by dust inhomogeneities on scales ≳100 pc. In runs with AGN, a clumpy, warm (≈250 K) dust component coexists with a colder (≈60 K) and more diffuse one, heated by stars. Warm dust provides up to ${50 {{\\ \\rm per\\ cent}}}$ of the total infrared (IR) luminosity, but only ${\\lesssim}0.1 {{\\ \\rm per\\ cent}}$ of the total mass content. The AGN boosts the MIR flux by 10–100 times with respect to star-forming galaxies, without significantly affecting the far-IR. Our simulations successfully reproduce the observed SED of bright (MUV ∼ −26) z ∼ 6 quasars, and show that these objects are part of complex, dust-rich merging systems, containing multiple sources (accreting black holes and/or star-forming galaxies) in agreement with recent HST and ALMA observations. Our results show that the proposed ORIGINS missions will be able to investigate the mid-IR (MIR) properties of dusty star-forming galaxies and to obtain good-quality spectra of bright quasars at z ∼ 6. Finally, the MIR-to-FIR flux ratio of faint (MUV ∼ −24) AGN is >10 times higher than for normal star-forming galaxies. This implies that combined JWST/ORIGINS/ALMA observations will be crucial to identify faint and/or dust-obscured AGN in the distant Universe."],["dc.description.abstract","ABSTRACT We investigate the infrared (IR) emission of high-redshift (z ∼ 6), highly star-forming (${{\\rm SFR}\\gt 100\\,{\\rm M}_{\\odot }\\, {\\rm yr}^{-1}}$) galaxies, with/without active galactic nuclei (AGN), using a suite of cosmological simulations featuring dust radiative transfer. Synthetic spectral energy distributions (SEDs) are used to quantify the relative contribution of stars/AGN to dust heating. In dusty (Md ≳ 3 × 107 M⊙) galaxies, ≳50–90 per cent of the ultraviolet (UV) radiation is obscured by dust inhomogeneities on scales ≳100 pc. In runs with AGN, a clumpy, warm (≈250 K) dust component coexists with a colder (≈60 K) and more diffuse one, heated by stars. Warm dust provides up to ${50 {{\\ \\rm per\\ cent}}}$ of the total infrared (IR) luminosity, but only ${\\lesssim}0.1 {{\\ \\rm per\\ cent}}$ of the total mass content. The AGN boosts the MIR flux by 10–100 times with respect to star-forming galaxies, without significantly affecting the far-IR. Our simulations successfully reproduce the observed SED of bright (MUV ∼ −26) z ∼ 6 quasars, and show that these objects are part of complex, dust-rich merging systems, containing multiple sources (accreting black holes and/or star-forming galaxies) in agreement with recent HST and ALMA observations. Our results show that the proposed ORIGINS missions will be able to investigate the mid-IR (MIR) properties of dusty star-forming galaxies and to obtain good-quality spectra of bright quasars at z ∼ 6. Finally, the MIR-to-FIR flux ratio of faint (MUV ∼ −24) AGN is >10 times higher than for normal star-forming galaxies. This implies that combined JWST/ORIGINS/ALMA observations will be crucial to identify faint and/or dust-obscured AGN in the distant Universe."],["dc.identifier.doi","10.1093/mnras/stab528"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/87674"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-441"],["dc.relation.eissn","1365-2966"],["dc.relation.issn","0035-8711"],["dc.title","Infrared emission of z ∼ 6 galaxies: AGN imprints"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]Details DOI2017Journal Article [["dc.bibliographiccitation.artnumber","043519"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Physical Review D"],["dc.bibliographiccitation.volume","95"],["dc.contributor.author","Du, Xiaolong"],["dc.contributor.author","Behrens, Christoph"],["dc.contributor.author","Niemeyer, Jens C."],["dc.contributor.author","Schwabe, Bodo"],["dc.date.accessioned","2020-12-10T18:25:21Z"],["dc.date.available","2020-12-10T18:25:21Z"],["dc.date.issued","2017"],["dc.description.abstract","In the context of structure formation with ultralight axion dark matter, we offer an alternative explanation for the mass relation of solitonic cores and their host halos observed in numerical simulations. Our argument is based entirely on the mass gain that occurs during major mergers of binary cores and largely independent of the initial core-halo mass relation assigned to hosts that have just collapsed. We find a relation between the halo mass M-h and corresponding core mass M-c, M-c proportional to M-h(2 beta-1), where (1-beta) is the core mass loss fraction. Following the evolution of core masses in stochastic merger trees, we find empirical evidence for our model. Our results are useful for statistically modeling the effects of dark matter cores on the properties of galaxies and their substructures in axion dark matter cosmologies."],["dc.identifier.doi","10.1103/PhysRevD.95.043519"],["dc.identifier.eissn","2470-0029"],["dc.identifier.isi","000394663900007"],["dc.identifier.issn","2470-0010"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/75661"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.relation.issn","2470-0029"],["dc.relation.issn","2470-0010"],["dc.title","Core-halo mass relation of ultralight axion dark matter from merger history"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]Details DOI WOS2020Journal Article [["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Physical Review D"],["dc.bibliographiccitation.volume","102"],["dc.contributor.author","Schwabe, Bodo"],["dc.contributor.author","Gosenca, Mateja"],["dc.contributor.author","Behrens, Christoph"],["dc.contributor.author","Niemeyer, Jens C."],["dc.contributor.author","Easther, Richard"],["dc.date.accessioned","2021-04-14T08:31:33Z"],["dc.date.available","2021-04-14T08:31:33Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1103/PhysRevD.102.083518"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/83637"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","2470-0029"],["dc.relation.issn","2470-0010"],["dc.title","Simulating mixed fuzzy and cold dark matter"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]Details DOI2013Journal Article [["dc.bibliographiccitation.artnumber","A5"],["dc.bibliographiccitation.firstpage","A5"],["dc.bibliographiccitation.journal","Astronomy and Astrophysics"],["dc.bibliographiccitation.volume","556"],["dc.contributor.author","Behrens, C."],["dc.contributor.author","Niemeyer, J."],["dc.date.accessioned","2018-11-07T09:21:41Z"],["dc.date.accessioned","2020-07-16T12:45:12Z"],["dc.date.available","2018-11-07T09:21:41Z"],["dc.date.available","2020-07-16T12:45:12Z"],["dc.date.issued","2013"],["dc.description.abstract","We investigate the correlations between the observed fraction of Lyman alpha emission from star-forming galaxies and the large scale structure by post-processing snapshots of a large, high resolution hydrodynamical simulation with a Lyman alpha radiative transfer code at redshifts z=4, 3, 2. We find correlations of the observed fraction with density, density gradient along the line of sight, velocity and velocity gradient along the line of sight, all within the same order of magnitude (tens of percent). Additionally, a correlation with the angular momentum of the dark matter halo is detected. In contrast to a previous study, we find no significant deformation of the 2-point correlation function due to selection effects from radiative transfer in the IGM within the limited statistics of the simulation volume."],["dc.description.sponsorship","DFG [SFB 963/1]"],["dc.identifier.doi","10.1051/0004-6361/201321172"],["dc.identifier.isi","000323893500005"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/10865"],["dc.identifier.scopus","2-s2.0-84880680801"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/67191"],["dc.identifier.url","http://www.scopus.com/inward/record.url?eid=2-s2.0-84880680801&partnerID=MN8TOARS"],["dc.language.iso","en"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.eissn","1432-0746"],["dc.relation.issn","0004-6361"],["dc.rights","Goescholar"],["dc.rights.uri","https://goedoc.uni-goettingen.de/licenses"],["dc.title","Effects of Lyman-alpha scattering in the IGM on clustering statistics of Lyman-alpha emitters"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]Details DOI WOS2017Journal Article [["dc.bibliographiccitation.firstpage","5206"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Monthly Notices of the Royal Astronomical Society"],["dc.bibliographiccitation.lastpage","5231"],["dc.bibliographiccitation.volume","474"],["dc.contributor.author","Knebe, Alexander"],["dc.contributor.author","Stoppacher, Doris"],["dc.contributor.author","Prada, Francisco"],["dc.contributor.author","Behrens, Christoph"],["dc.contributor.author","Benson, Andrew"],["dc.contributor.author","Cora, Sofia A"],["dc.contributor.author","Croton, Darren J"],["dc.contributor.author","Padilla, Nelson D"],["dc.contributor.author","Ruiz, Andrés N"],["dc.contributor.author","Sinha, Manodeep"],["dc.contributor.author","Stevens, Adam R H"],["dc.contributor.author","Vega-Martínez, Cristian A"],["dc.contributor.author","Behroozi, Peter"],["dc.contributor.author","Gonzalez-Perez, Violeta"],["dc.contributor.author","Gottlöber, Stefan"],["dc.contributor.author","Klypin, Anatoly A"],["dc.contributor.author","Yepes, Gustavo"],["dc.contributor.author","Enke, Harry"],["dc.contributor.author","Libeskind, Noam I"],["dc.contributor.author","Riebe, Kristin"],["dc.contributor.author","Steinmetz, Matthias"],["dc.date.accessioned","2020-12-10T18:19:27Z"],["dc.date.available","2020-12-10T18:19:27Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1093/mnras/stx2662"],["dc.identifier.eissn","1365-2966"],["dc.identifier.issn","0035-8711"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/75252"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","MultiDark-Galaxies: data release and first results"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]Details DOI2016Journal Article Research Paper [["dc.bibliographiccitation.artnumber","79"],["dc.bibliographiccitation.firstpage","79"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","The Astrophysical Journal"],["dc.bibliographiccitation.volume","817"],["dc.contributor.author","Hagen, Alex"],["dc.contributor.author","Zeimann, Gregory R."],["dc.contributor.author","Behrens, Christoph"],["dc.contributor.author","Ciardullo, Robin"],["dc.contributor.author","Gebhardt, Henry S. Grasshorn"],["dc.contributor.author","Gronwall, Caryl"],["dc.contributor.author","Bridge, Joanna S."],["dc.contributor.author","Fox, Derek B."],["dc.contributor.author","Schneider, Donald P."],["dc.contributor.author","Trump, Jonathan R."],["dc.contributor.author","Blanc, Guillermo A."],["dc.contributor.author","Chiang, Yi-Kuan"],["dc.contributor.author","Chonis, Taylor S."],["dc.contributor.author","Finkelstein, Steven L."],["dc.contributor.author","Hill, Gary J."],["dc.contributor.author","Jogee, Shardha"],["dc.contributor.author","Gawiser, Eric"],["dc.date.accessioned","2020-12-10T18:47:31Z"],["dc.date.available","2020-12-10T18:47:31Z"],["dc.date.issued","2016"],["dc.description.abstract","We compare the physical and morphological properties of z similar to 2 Ly alpha emitting galaxies (LAEs) identified in the HETDEX Pilot Survey and narrow band studies with those of z similar to 2 optical emission line selected galaxies (oELGs) identified via HST WFC3 infrared grism spectroscopy. Both sets of galaxies extend over the same range in stellar mass (7.5 < log M/M-circle dot < 10.5), size (0.5 < R < 3.0 kpc), and star formation rate (similar to 1 < SFR < 100 M-circle dot yr(-1)). Remarkably, a comparison of the most commonly used physical and morphological parameters-stellar mass, half-light radius, UV slope, SFR, ellipticity, nearest neighbor distance, star formation surface density, specific SFR, [O III] luminosity, and [O III] equivalent width-reveals no statistically significant differences between the populations. This suggests that the processes and conditions which regulate the escape of Ly alpha from a z similar to 2 star-forming galaxy do not depend on these quantities. In particular, the lack of dependence on the UV slope suggests that Ly alpha emission is not being significantly modulated by diffuse dust in the interstellar medium. We develop a simple model of Ly alpha emission that connects LAEs to all high-redshift starforming galaxies where the escape of Ly alpha depends on the sightline through the galaxy. Using this model, we find that mean solid angle for Ly alpha escape is Omega(Ly alpha) = 2.4 +/- 0.8 steradians; this value is consistent with those calculated from other studies."],["dc.identifier.doi","10.3847/0004-637X/817/1/79"],["dc.identifier.eissn","1538-4357"],["dc.identifier.isi","000368872400079"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78790"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","1538-4357"],["dc.relation.issn","0004-637X"],["dc.title","HST Emission Line Galaxies at Z Similar to 2: Comparing Physical Properties of Lyman Alpha and Optical Emission Line Selected Galaxies"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]Details DOI WOS2022Journal Article [["dc.bibliographiccitation.artnumber","stac1281"],["dc.bibliographiccitation.journal","Monthly Notices of the Royal Astronomical Society"],["dc.contributor.author","Pallottini, A"],["dc.contributor.author","Ferrara, A"],["dc.contributor.author","Gallerani, S"],["dc.contributor.author","Behrens, C"],["dc.contributor.author","Kohandel, M"],["dc.contributor.author","Carniani, S"],["dc.contributor.author","Vallini, L"],["dc.contributor.author","Salvadori, S"],["dc.contributor.author","Gelli, V"],["dc.contributor.author","Sommovigo, L"],["dc.contributor.author","Pizzati, E"],["dc.date.accessioned","2022-07-01T07:35:03Z"],["dc.date.available","2022-07-01T07:35:03Z"],["dc.date.issued","2022"],["dc.description.abstract","Abstract We introduce SERRA, a suite of zoom-in high-resolution (1.2 × 104 M⊙, ≃ 25 pc at z = 7.7) cosmological simulations including non-equilibrium chemistry and on-the-fly radiative transfer. The outputs are post-processed to derive galaxy UV+FIR continuum and emission line properties. Results are compared with available multi-wavelength data to constrain the physical properties (e.g. star formation rates, stellar/gas/dust mass, metallicity) of high-redshift 6 ≲ z ≲ 15 galaxies. This flagship paper focuses on the z = 7.7 sub-sample, including 202 galaxies with stellar mass 107 M⊙ ≲ M⋆ ≲ 5 × 1010 M⊙, and specific star formation ranging from sSFR ∼ 100 Gyr−1 in young, low-mass galaxies to ∼10 Gyr−1 for older, massive ones. At this redshift, serra galaxies are typically bursty, i.e. they are located above the Schmidt-Kennicutt relation by a factor $\\kappa _s = 3.03^{+4.9}_{-1.8}$, consistent with recent findings for [O iii] and [C ii] emitters at high-z. They also show relatively large IRX =LFIR/LUV values as a result of their compact/clumpy morphology effectively blocking the stellar UV luminosity. Note that this conclusion might be affected by insufficient spatial resolution at the molecular cloud level. We confirm that early galaxies lie on the standard [C ii]ehB\\rm SFR$ relation; their observed L[OIII]/L[CII] ≃ 1 − 10 ratios can be reproduced by a part of the SERRA galaxies without the need of a top-heavy IMF and/or anomalous C/O abundances. [O i] line intensities are similar to local ones, making ALMA high-z detections challenging but feasible ($\\sim 6\\, \\rm hr$ for an SFR of 50 M⊙ yr−1)."],["dc.identifier.doi","10.1093/mnras/stac1281"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/112074"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-581"],["dc.relation.eissn","1365-2966"],["dc.relation.issn","0035-8711"],["dc.title","A survey of high- z galaxies: SERRA simulations"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]Details DOI2007Journal Article [["dc.bibliographiccitation.firstpage","1306"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","Clinical Chemistry"],["dc.bibliographiccitation.lastpage","1314"],["dc.bibliographiccitation.volume","53"],["dc.contributor.author","Reinshagen, Max"],["dc.contributor.author","Schuetz, Ekkehard"],["dc.contributor.author","Armstrong, Victor William"],["dc.contributor.author","Behrens, Christoph"],["dc.contributor.author","von Tirpitz, Christian"],["dc.contributor.author","Stallmach, Andreas"],["dc.contributor.author","Herfarth, Hans"],["dc.contributor.author","Stein, Juergen"],["dc.contributor.author","Bias, Peter"],["dc.contributor.author","Adler, Guido"],["dc.contributor.author","Shipkova, Maria"],["dc.contributor.author","Kruis, Wolfgang"],["dc.contributor.author","Oellerich, Michael"],["dc.contributor.author","von Ahsen, Nicolas"],["dc.date.accessioned","2018-11-07T11:00:55Z"],["dc.date.available","2018-11-07T11:00:55Z"],["dc.date.issued","2007"],["dc.description.abstract","Background: A prospective randomized trial in patients with Crohn disease studied whether 6-thioguanine nucleotide (6-TGN) concentration-adapted azathioprine (AZA) therapy is clinically superior to a standard dose of 2.5 mg/kg/day AZA. Methods: After 2 weeks of standard therapy, patients (n = 71) were randomized into standard (n = 32) or adapted-dose (n = 25) groups; 14 patients dropped out before randomization. In the adapted group, the AZA dose was adjusted to maintain 6-TGN concentrations between 250 and 400 pmol/8 x 10(8) erythrocytes (Ery), Response criteria were the number of patients in remission after 16 weeks without steroids (primary) and remission after 24 weeks, frequency of side effects, and quality of life (secondary). Results: After 16 weeks, 14 of 32 (43.8%) patients in the standard group vs 11 of 25 (44%) in the adapted group were in remission without steroids (intent-to-treat analysis). After 24 weeks, 43.8% vs 40% were in remission. No significant differences were found concerning quality of life, disease activity, 6-TGN concentrations, AZA dose, or dropouts due to side effects. Sixty-six patients had a wild-type thiopurine S-methyltransferase (TPMT) genotype, with TPMT activities of 8 to 20 nmol/(mL Ery x h). Five patients (dropouts after randomization) were heterozygous, with TPMT activities < 8 nmol/(mL Ery x h). 6-Methyl mercaptopurine (6-MMP) concentrations > 5700 pmol/8 x 10(8) Ery were not associated with hepatotoxicity. Conclusion: Standard and adapted dosing with the provided dosing scheme led to identical 6-TGN concentrations and remission rates. Adapted dosing had no apparent clinical benefit for patients with TPMT activity between 8 and 20 nmol/(mL Ery x h). Additionally, 6-MMP monitoring had no predictive value for hepatotoxicity. (c) 2007 American Association for Clinical Chemistry."],["dc.identifier.doi","10.1373/clinchem.2007.086215"],["dc.identifier.isi","000247558000019"],["dc.identifier.pmid","17495015"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/51032"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","0009-9147"],["dc.title","6-thioguanine nucleotide-adapted azathioprine therapy does not lead to higher remission rates than standard therapy in chronic active crohn disease: results from a randomized, controlled, open trial"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]Details DOI PMID PMC WOS2020Journal Article [["dc.bibliographiccitation.firstpage","3371"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Monthly Notices of the Royal Astronomical Society"],["dc.bibliographiccitation.lastpage","3380"],["dc.bibliographiccitation.volume","496"],["dc.contributor.author","Benson, Andrew"],["dc.contributor.author","Behrens, Christoph"],["dc.contributor.author","Lu, Yu"],["dc.date.accessioned","2021-04-14T08:24:14Z"],["dc.date.available","2021-04-14T08:24:14Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1093/mnras/staa1777"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/81212"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1365-2966"],["dc.relation.issn","0035-8711"],["dc.title","A random-walk model for dark matter halo spins"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]Details DOI