Hinz, Jose

[["dc.bibliographiccitation.firstpage","842"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","Der Anaesthesist"],["dc.bibliographiccitation.lastpage","850"],["dc.bibliographiccitation.volume","59"],["dc.contributor.author","Braeuer, Anselm"],["dc.contributor.author","Waeschle, Reiner M."],["dc.contributor.author","Heise, Daniel"],["dc.contributor.author","Perl, Tal Naggan"],["dc.contributor.author","Hinz, Jose Maria"],["dc.contributor.author","Quintel, M."],["dc.contributor.author","Bauer, M."],["dc.date.accessioned","2018-11-07T08:39:25Z"],["dc.date.available","2018-11-07T08:39:25Z"],["dc.date.issued","2010"],["dc.description.abstract","Despite the broad application of intraoperative warming new studies still show a high incidence of perioperative hypothermia. Therefore a prewarming program in the preoperative holding area was started. The efficacy of the prewarming program was assessed with an accompanying quality assurance check sheet over a period of 3 months. During the 3 month test period 127 patients were included. The median length from arrival in the holding area to beginning prewarming was 6 min and the average duration of prewarming was 46 +/- 38 min. During prewarming the core temperature rose by 0.3 +/- 0.4A degrees C to 37.1 +/- 0.5A degrees C and decreased to 36.3 +/- 0.5A degrees C after induction of anesthesia. At the end of the operation the core temperature was 36.4 +/- 0.5A degrees C and 14% of the patients were hypothermic. These data allow 2 conclusions: 1. Prewarming in the holding area is possible with a sufficient duration. 2. Prewarming is highly efficient even when performed over a relatively short duration."],["dc.identifier.doi","10.1007/s00101-010-1772-0"],["dc.identifier.isi","000281844600007"],["dc.identifier.pmid","20703440"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/18992"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0003-2417"],["dc.title","Preoperative prewarming as a routine measure. First experiences"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","354"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Der Anaesthesist"],["dc.bibliographiccitation.lastpage","+"],["dc.bibliographiccitation.volume","61"],["dc.contributor.author","Wiese, Christoph Hermann"],["dc.contributor.author","Schepp, C. P."],["dc.contributor.author","Bergmann, I."],["dc.contributor.author","Hinz, Jose Maria"],["dc.contributor.author","Graf, Bernhard Martin"],["dc.contributor.author","Lassen, Christoph L."],["dc.date.accessioned","2018-11-07T09:11:25Z"],["dc.date.available","2018-11-07T09:11:25Z"],["dc.date.issued","2012"],["dc.description.abstract","The necessity of limiting resource in healthcare systems is becoming increasingly more evident. The population has requirements especially in the field of healthcare which are principally unlimited. However, there are only limited financial resources which can be used to satisfy the wishes of the population. For this reason rationing models are being discussed increasingly more often. One example of these models is called age rationing which means that defined services are only offered to patients up to a particular age. The aim of this article is to discuss the model of age rationing in the context of an optimized use of resources in the healthcare system."],["dc.identifier.doi","10.1007/s00101-012-2009-1"],["dc.identifier.isi","000303350600008"],["dc.identifier.pmid","22526746"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/26720"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0003-2417"],["dc.title","Age rationing. Means of resource allocation in healthcare systems"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","39"],["dc.bibliographiccitation.journal","Journal of Cardiothoracic Surgery"],["dc.bibliographiccitation.volume","7"],["dc.contributor.author","Hinz, Jose"],["dc.contributor.author","Gehoff, Philipp"],["dc.contributor.author","Schotola, Hanna"],["dc.contributor.author","Hosseini, Morteza Tavakkoli"],["dc.contributor.author","Didilis, Vassilios N."],["dc.contributor.author","Jebran, Ahmad Fawad"],["dc.contributor.author","Gehoff, Anastasia"],["dc.contributor.author","Wiese, Christoph Hermann"],["dc.contributor.author","Schulz, Egbert Godehard"],["dc.contributor.author","Schoendube, Friedrich Albert"],["dc.contributor.author","Popov, Aron Frederik"],["dc.date.accessioned","2018-11-07T09:11:03Z"],["dc.date.available","2018-11-07T09:11:03Z"],["dc.date.issued","2012"],["dc.description.abstract","Background: Peri-operative statin therapy in cardiac surgery cases is reported to reduce the rate of mortality, stroke, postoperative atrial fibrillation, and systemic inflammation. Systemic inflammation could affect the hemodynamic parameters and stability. We set out to study the effect of statin therapy on perioperative hemodynamic parameters and its clinical outcome. Methods: In a single center study from 2006 to 2007, peri-operative hemodynamic parameters of 478 patients, who underwent cardiac surgery with cardiopulmonary bypass, were measured. Patients were divided into those who received perioperative statin therapy (n = 276; statin group) and those who did not receive statin therapy (n = 202; no-statin group). The two groups were compared together using Kolmogorov-Smirnov-Test, Fisher's-Exact-Test, and Student's-T-test. A p value < 0.05 was considered as significant. Results: There was no significant difference in the preoperative risk factors. Onset of postoperative atrial fibrillation was not affected by statin therapy. Extended hemodynamic measurements revealed no significant difference between the two groups, apart from Systemic Vascular Resistance Index (SVRI). The no-statin group had a significantly higher SVRI (882 +/- 206 vs. 1050 +/- 501 dyn s/cm(5)/m(2), p = 0.022). Inotropic support was the same in both groups and no significant difference in the mortality rate was noticed. Also, hemodynamic parameters were not affected by different types and doses of statins. Conclusions: Perioperative statin therapy for patients undergoing on-pump coronary bypass grafting or valvular surgery, does not affect the hemodynamic parameters and its clinical outcome."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2012"],["dc.identifier.doi","10.1186/1749-8090-7-39"],["dc.identifier.isi","000306370800001"],["dc.identifier.pmid","22533985"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/8510"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/26638"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Biomed Central Ltd"],["dc.relation.issn","1749-8090"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Hemodynamic effects of peri-operative statin therapy in on-pump cardiac surgery patients"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","217"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","AINS - Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie"],["dc.bibliographiccitation.lastpage","224"],["dc.bibliographiccitation.volume","40"],["dc.contributor.author","Moerer, Onnen"],["dc.contributor.author","Bittner, J."],["dc.contributor.author","Hinz, Jose Maria"],["dc.contributor.author","Sydow, M."],["dc.date.accessioned","2018-11-07T11:09:13Z"],["dc.date.available","2018-11-07T11:09:13Z"],["dc.date.issued","2005"],["dc.description.abstract","Objective: Onset time and recovery from non depolarising neuromuscular blockade depends on the tested muscle and is influenced by the age of the patient. This study compares the neuromuscular blocking effect of rocuronium on the diaphragm, adductor pollicis and orbicularis oculi muscle in young and elderly patients. Methods: After institutional ethics committee approval and written informed consent, 20 adult patients (ASA I - II), age 18 - 59 and > 65, have been included. Neuromuscular response was measured by accelerography for the adductor pollicis and orbicularis oculi muscle. Monitoring of the diaphragm consisted of measurement of the airway pressure against an occluded tracheal tube during magnetic phrenic nerve stimulation. Onset time and recovery were measured after injection of 0.6 mg/kg Rocuronium. Results: The adductor pollicis had the fastest onset time (young 2.3 min, old 2.2 min), followed by diaphragm (young 3.6 min, old 3.4 min) and orbicularis oculi muscle (young 3.7 min, old 4.8 min). There was a complete blockade of the diaphragm in 50% of all patients (Adductor pollicis 100%, orbicularis oculi 40%). Neuromuscular recovery, recovery index and TOF 0.8 differed significantly between young and elderly patients. Onset of recovery was earlier at the diaphragm (young 15.9 min, old 22.0 min) compared to the peripheral muscles (adductor pollicis young 25.6 min, old 37.9 min, orbicularis oculi young 23.8 min, old 27.5 min). Conclusion: 2fould ED95 of rocuronium often results in an incomplete neuromuscular blockade of the diaphragm. Therefore monitoring of the peripheral muscles in patients given a single dose of rocuronium often overestimates the degree of diaphragmatic relaxation, but is a save predictor of recovery. Especially in elderly patients were prolonged neuro-muscular blockade should be expected, a neuromuscular monitoring is recommended."],["dc.identifier.doi","10.1055/s-2005-861037"],["dc.identifier.isi","000228422100009"],["dc.identifier.pmid","15832241"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/52959"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Georg Thieme Verlag Kg"],["dc.relation.issn","0939-2661"],["dc.title","Effect of rocuronium on the diaphragm, musculus adductor pollicis and orbicularis oculi in two groups of different age"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","Critical Care Medicine"],["dc.bibliographiccitation.volume","29"],["dc.contributor.author","Hinz, Jose Maria"],["dc.contributor.author","Neumann, P."],["dc.contributor.author","Hahn, G."],["dc.contributor.author","Dudykevych, T."],["dc.contributor.author","Hellige, Gerhard"],["dc.contributor.author","Burchardi, Hilmar"],["dc.date.accessioned","2018-11-07T11:20:41Z"],["dc.date.available","2018-11-07T11:20:41Z"],["dc.date.issued","2001"],["dc.format.extent","A84"],["dc.identifier.isi","000172920900273"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/55599"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Lippincott Williams & Wilkins"],["dc.publisher.place","Philadelphia"],["dc.relation.issn","0090-3493"],["dc.title","Regional pulmonary pressure volume curves by electrical impedance tomography"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","337"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Current Cardiology Reviews"],["dc.bibliographiccitation.lastpage","342"],["dc.bibliographiccitation.volume","6"],["dc.contributor.author","Heidrich, Florian"],["dc.contributor.author","Schotola, Hanna"],["dc.contributor.author","F. Popov, Aron"],["dc.contributor.author","Sohns, Christian"],["dc.contributor.author","Schuenemann, Julia"],["dc.contributor.author","Friedrich, Martin"],["dc.contributor.author","O. Coskun, Kasim"],["dc.contributor.author","von Lewinski, Dirk"],["dc.contributor.author","Hinz, Jose"],["dc.contributor.author","D. Schmitto, Jan"],["dc.date.accessioned","2021-06-01T10:48:36Z"],["dc.date.available","2021-06-01T10:48:36Z"],["dc.date.issued","2010"],["dc.identifier.doi","10.2174/157340310793566073"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/85994"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.relation.issn","1573-403X"],["dc.title","AMPK - Activated Protein Kinase and its Role in Energy Metabolism of the Heart"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","70"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Journal of Clinical Medicine"],["dc.bibliographiccitation.volume","8"],["dc.contributor.affiliation","Mewes, Caspar; \t\t \r\n\t\t Department of Anesthesiology, University Medical Center, Georg August University, D-37075 Goettingen, Germany,"],["dc.contributor.affiliation","Büttner, Benedikt; \t\t \r\n\t\t Department of Anesthesiology, University Medical Center, Georg August University, D-37075 Goettingen, Germany,"],["dc.contributor.affiliation","Hinz, José; \t\t \r\n\t\t Department of Anesthesiology and Intensive Care Medicine, Klinikum Region Hannover, D-30459 Hannover, Germany,"],["dc.contributor.affiliation","Alpert, Ayelet; \t\t \r\n\t\t Faculty of Medicine, Technion−Israeli Institute of Technology, 31096 Haifa, Israel,"],["dc.contributor.affiliation","Popov, Aron-Frederik; \t\t \r\n\t\t Department of Thoracic and Cardiovascular Surgery, University Medical Center, Eberhard Karls University, D-72076 Tuebingen, Germany,"],["dc.contributor.affiliation","Ghadimi, Michael; \t\t \r\n\t\t Department of General and Visceral Surgery, University Medical Center, Georg August University, D-37075 Goettingen, Germany,"],["dc.contributor.affiliation","Beissbarth, Tim; \t\t \r\n\t\t Department of Medical Bioinformatics, University Medical Center, Georg August University, D-37077 Goettingen, Germany,"],["dc.contributor.affiliation","Tzvetkov, Mladen; \t\t \r\n\t\t Department of Pharmacology, University Medical Center, Ernst-Moritz-Arndt-University, D-17487 Greifswald, Germany,"],["dc.contributor.affiliation","Jensen, Ole; \t\t \r\n\t\t Department of Clinical Pharmacology, University Medical Center, Georg August University, D-37075 Goettingen, Germany,"],["dc.contributor.affiliation","Runzheimer, Julius; \t\t \r\n\t\t Department of Anesthesiology, University Medical Center, Georg August University, D-37075 Goettingen, Germany,"],["dc.contributor.affiliation","Quintel, Michael; \t\t \r\n\t\t Department of Anesthesiology, University Medical Center, Georg August University, D-37075 Goettingen, Germany,"],["dc.contributor.affiliation","Shen-Orr, Shai; \t\t \r\n\t\t Faculty of Medicine, Technion−Israeli Institute of Technology, 31096 Haifa, Israel,"],["dc.contributor.affiliation","Bergmann, Ingo; \t\t \r\n\t\t Department of Anesthesiology, University Medical Center, Georg August University, D-37075 Goettingen, Germany,"],["dc.contributor.affiliation","Mansur, Ashham; \t\t \r\n\t\t Department of Anesthesiology, University Medical Center, Georg August University, D-37075 Goettingen, Germany,"],["dc.contributor.author","Mewes, Caspar"],["dc.contributor.author","Büttner, Benedikt"],["dc.contributor.author","Hinz, José Maria"],["dc.contributor.author","Alpert, Ayelet"],["dc.contributor.author","Popov, Aron-Frederik"],["dc.contributor.author","Ghadimi, Michael B."],["dc.contributor.author","Beißbarth, Tim"],["dc.contributor.author","Tzvetkov, Mladen Vassilev"],["dc.contributor.author","Jensen, Ole"],["dc.contributor.author","Runzheimer, Julius"],["dc.contributor.author","Quintel, Michael I."],["dc.contributor.author","Shen-Orr, Shai"],["dc.contributor.author","Bergmann, Ingo"],["dc.contributor.author","Mansur, Ashham"],["dc.date.accessioned","2019-07-09T11:49:58Z"],["dc.date.available","2019-07-09T11:49:58Z"],["dc.date.issued","2019"],["dc.date.updated","2022-02-09T13:23:19Z"],["dc.description.abstract","Cytotoxic T lymphocyte-associated protein 4 (CTLA-4) is a coinhibitory checkpoint protein expressed on the surface of T cells. A recent study by our working group revealed that the rs231775 single nucleotide polymorphism (SNP) in the CTLA-4 gene was associated with the survival of patients with sepsis and served as an independent prognostic variable. To further investigate the impact of CTLA-4 genetic variants on sepsis survival, we examined the effect of two functional SNPs, CTLA-4 rs733618 and CTLA-4 rs3087243, and inferred haplotypes, on the survival of 644 prospectively enrolled septic patients. Kaplan⁻Meier survival analysis revealed significantly lower 90-day mortality for rs3087243 G allele carriers (n = 502) than for AA-homozygous (n = 142) patients (27.3% vs. 40.8%, p = 0.0024). Likewise, lower 90-day mortality was observed for TAA haplotype-negative patients (n = 197; compound rs733618 T/rs231775 A/rs3087243 A) than for patients carrying the TAA haplotype (n = 447; 24.4% vs. 32.9%, p = 0.0265). Carrying the rs3087243 G allele hazard ratio (HR): 0.667; 95% confidence interval (CI): 0.489⁻0.909; p = 0.0103) or not carrying the TAA haplotype (HR: 0.685; 95% CI: 0.491⁻0.956; p = 0.0262) remained significant covariates for 90-day survival in the multivariate Cox regression analysis and thus served as independent prognostic variables. In conclusion, our findings underscore the significance of CTLA-4 genetic variants as predictors of survival of patients with sepsis."],["dc.description.sponsorship","Volkswagen Foundation"],["dc.identifier.doi","10.3390/jcm8010070"],["dc.identifier.eissn","2077-0383"],["dc.identifier.pmid","30634576"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/15817"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/59664"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.publisher","MDPI"],["dc.relation.eissn","2077-0383"],["dc.relation.issn","2077-0383"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.subject.ddc","610"],["dc.title","CTLA-4 Genetic Variants Predict Survival in Patients with Sepsis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1443"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","Acta Anaesthesiologica Scandinavica"],["dc.bibliographiccitation.lastpage","1448"],["dc.bibliographiccitation.volume","49"],["dc.contributor.author","Neumann, P."],["dc.contributor.author","Schubert, A."],["dc.contributor.author","Heuer, J. F."],["dc.contributor.author","Hinz, Jose Maria"],["dc.contributor.author","Quintel, M."],["dc.contributor.author","Klockgether-Radke, Adelbert"],["dc.date.accessioned","2018-11-07T10:54:25Z"],["dc.date.available","2018-11-07T10:54:25Z"],["dc.date.issued","2005"],["dc.description.abstract","Backround: During mechanical ventilatory support, spontaneous breathing has been linked to improved hemodynamics. These findings may be explained by a decrease in intrathoracic pressure which may improve venous return to the heart. Such a mechanism should result in a dose-response relation between the amount of spontaneous breathing and an increase in the global end-diastolic volume (GEDV) and cardiac output (Q(t)). Methods: To test this hypothesis, 15 patients were studied after major elective surgery during weaning from mechanical ventilation using bilevel positive airway pressure (BIPAP). BIPAP allows unrestricted spontaneous breathing during every phase of the respiratory cycle. Thus, ventilatory support was modified by changing the mechanical respiratory rate only, whereas inspiratory airway pressure and PEEP were kept constant. GEDV and Q(t) were measured by transpulmonary thermodilution. Results: GEDV (P = 0.055), stroke volume (P = 0.027) and subsequently also Q(t) (P < 0.001) increased when spontaneous breathing increased. In contrast, no difference was observed for central venous pressure (P = 0.19). Conclusion: The beneficial hemodynamic effects of spontaneous breathing during mechanical ventilatory support can partially be explained by improved venous return to the heart which increases stroke volume and Q(t)."],["dc.identifier.doi","10.1111/j.1399-6576.2005.00868.x"],["dc.identifier.isi","000232557500006"],["dc.identifier.pmid","16223387"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/49557"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Blackwell Publishing"],["dc.relation.issn","0001-5172"],["dc.title","Hemodynamic effects of spontaneous breathing in the post-operative period"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","297"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Open Medicine"],["dc.bibliographiccitation.lastpage","305"],["dc.bibliographiccitation.volume","10"],["dc.contributor.author","Schotola, Hanna"],["dc.contributor.author","Kirsch, Karl-Christian"],["dc.contributor.author","Hoecker, Jan"],["dc.contributor.author","Egan, Michael"],["dc.contributor.author","Buettner, Benedikt"],["dc.contributor.author","Wiese, Christoph"],["dc.contributor.author","Mansur, Ashham"],["dc.contributor.author","Hinz, Jose Maria"],["dc.contributor.author","Bergmann, Ingo"],["dc.date.accessioned","2018-11-07T10:02:29Z"],["dc.date.available","2018-11-07T10:02:29Z"],["dc.date.issued","2015"],["dc.description.abstract","Background: Pain after arthroscopic shoulder surgery is often severe, and establishing a pain treatment regimen that does not delay discharge can be challenging. The reported ability of ketamine to prevent opioid-induced hyperalgesia has not been investigated in this particular setting. Methods: 300 adult patients scheduled for shoulder arthroscopy under general anesthesia were recruited for this observational clinical trial and were allotted to either receive 1mg/kg IV bolus of ketamine before surgery (ketamine group, KG) or to a control group (CG) without ketamine. NRS pain scores were obtained on the operative day and on postoperative days 1 and 2 and compared between groups. Secondary variables were blood pressure, heart rate, process times, satisfaction with the anesthetic and unwanted effects. Results: Pain severity did not differ significantly between the groups at any time. Propofol injection rate and cumulative dose were higher in the KG. Heart rates and blood pressures were similar. Time to emergence and time in PACU were longer and vomiting was more frequent in patients given ketamine. Conclusion: Preoperative low-dose ketamine added to a general anesthetic does not reduce perioperative pain after outpatient shoulder arthroscopy. It increases procedural times and the incidence of PONV."],["dc.description.sponsorship","Open-Access Publikationsfonds 2015"],["dc.identifier.doi","10.1515/med-2015-0043"],["dc.identifier.isi","000371696900026"],["dc.identifier.pmid","28352709"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/12371"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/38233"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","De Gruyter Open Ltd"],["dc.relation.issn","2391-5463"],["dc.rights","CC BY-NC-ND 3.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc-nd/3.0"],["dc.title","Ketamine in outpatient arthroscopic shoulder surgery: Effects on postoperative pain, hemodynamic stability and process times"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","50"],["dc.bibliographiccitation.journal","BMC Anesthesiology"],["dc.bibliographiccitation.volume","14"],["dc.contributor.author","Janssen, Hauke"],["dc.contributor.author","von Stosch, Roland"],["dc.contributor.author","Poeschl, Rupert"],["dc.contributor.author","Buettner, Benedikt"],["dc.contributor.author","Bauer, Martin"],["dc.contributor.author","Hinz, Jose Maria"],["dc.contributor.author","Bergmann, Ingo"],["dc.date.accessioned","2018-11-07T09:38:44Z"],["dc.date.available","2018-11-07T09:38:44Z"],["dc.date.issued","2014"],["dc.description.abstract","Background: Shoulder surgery is often performed in the beach-chair position, a position associated with arterial hypotension and subsequent risk of cerebral ischaemia. It can be performed under general anaesthesia or with an interscalene brachial plexus block, each of which has specific advantages but also specific negative effects on blood pressure control. It would be worthwhile to combine the advantages of the two, but the effects of the combination on the circulation are not well investigated. We studied blood pressure, heart rate, and incidence of adverse circulatory events in patients undergoing shoulder surgery in general anaesthesia with or without an interscalene block. Methods: Prospective, randomised, blinded study in outpatients (age 18 to 80 years) undergoing shoulder arthroscopy. General anaesthesia was with propofol/opioid, interscalene block with 40 ml 1% mepivacaine. Hypotension requiring treatment was defined as a mean arterial pressure < 60 mmHg or a systolic pressure < 80% of baseline; relevant bradycardia was a heart rate < 50 bpm with a decrease in blood pressure. Results: Forty-two patients had general anaesthesia alone, 41 had general anaesthesia plus interscalene block. The average systolic blood pressure under anaesthesia in the beach-chair position was 114 +/- 7.3 vs. 116 +/- 8.3 mmHg (p = 0.09; all comparisons General vs. General-Regional). The incidence of a mean arterial pressure under 60 mmHg or a decrease in systolic pressure of more than 20% from baseline was 64% vs. 76% (p = 0.45). The number of patients with a heart rate lower than 50 and a concomitant blood pressure decrease was 8 vs. 5 (p = 0.30). Conclusion: One can safely combine interscalene block with general anaesthesia for surgery in the beach-chair position in ASA I and II patients."],["dc.description.sponsorship","departmental funds"],["dc.identifier.doi","10.1186/1471-2253-14-50"],["dc.identifier.isi","000338572300001"],["dc.identifier.pmid","25002832"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/10431"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/33130"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Biomed Central Ltd"],["dc.relation.issn","1471-2253"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Blood pressure response to combined general anaesthesia/interscalene brachial plexus block for outpatient shoulder arthroscopy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]