Müller, Luise

[["dc.bibliographiccitation.firstpage","63"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Ethik in der Medizin"],["dc.bibliographiccitation.lastpage","70"],["dc.bibliographiccitation.volume","18"],["dc.contributor.author","Ude-Koeller, Susanne"],["dc.contributor.author","Müller, Luise"],["dc.contributor.author","Wiesemann, Claudia"],["dc.date.accessioned","2017-10-16T10:54:26Z"],["dc.date.available","2017-10-16T10:54:26Z"],["dc.date.issued","2006"],["dc.description.abstract","Wir diskutieren ethische Probleme der medizinischen Behandlung intersexueller Kinder. Gefragt wird nach dem Stellenwert von Elternwünschen nach eindeutiger Geschlechtszuweisung sowie nach den Konfliktfeldern, die zum einen zwischen konkurrierenden Wunschvorstellungen der Eltern und der behandelnden Ärzte, zum andern zwischen Kindeswohl und Kinderrechten entstehen können. Gegenwärtig wird Neugeborenen mit anatomisch uneindeutigem Genital trotz unsicherer Prognose über die Behandlungsergebnisse oft noch ein Geschlecht zugewiesen und operativ erstellt. Dieses Vorgehen ist von verschiedenen Seiten ethisch heftig kritisiert worden. Kipnis u. Diamond forderten 1998 im „Journal of Clinical Ethics“ ein Moratorium für alle nicht vital indizierten geschlechtskorrigierenden Eingriffe. Diese Forderung orientiert sich am Interesse des zukünftigen Erwachsenen, betont dessen prospektive Autonomie und klammert den Elternwunsch aus. Dieses „Modell des antizipierten Konsenses“ kann jedoch mit Bezug auf Neugeborene und Kleinkinder bedeutsame Aspekte des Eltern-Kind-Verhältnisses nicht angemessen erfassen. Im Aufsatz werden Argumente angeführt, die es aus Sicht einer Ethik der Elternschaft rechtfertigen, ethische Entscheidungen auf der Basis eines beziehungsorientierten Modells zu treffen. In unserem Modell fallen Elternwünsche ethisch ins Gewicht."],["dc.identifier.doi","10.1007/s00481-006-0414-1"],["dc.identifier.gro","3146724"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/9396"],["dc.language.iso","de"],["dc.notes.status","final"],["dc.relation.issn","0935-7335"],["dc.title","Junge oder Mädchen?"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.peerReviewed","no"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2292"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","Human Reproduction"],["dc.bibliographiccitation.lastpage","2298"],["dc.bibliographiccitation.volume","23"],["dc.contributor.author","Muller, T."],["dc.contributor.author","Eildermann, K."],["dc.contributor.author","Dhir, R."],["dc.contributor.author","Schlatt, S."],["dc.contributor.author","Behr, R."],["dc.date.accessioned","2022-10-06T13:34:55Z"],["dc.date.available","2022-10-06T13:34:55Z"],["dc.date.issued","2008"],["dc.identifier.doi","10.1093/humrep/den253"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/116012"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.eissn","1460-2350"],["dc.relation.issn","0268-1161"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","Glycan stem-cell markers are specifically expressed by spermatogonia in the adult non-human primate testis"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","815"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Molecular Human Reproduction"],["dc.bibliographiccitation.lastpage","820"],["dc.bibliographiccitation.volume","13"],["dc.contributor.author","Behr, R."],["dc.contributor.author","Deller, C."],["dc.contributor.author","Godmann, M."],["dc.contributor.author","Muller, T."],["dc.contributor.author","Bergmann, M."],["dc.contributor.author","Ivell, R."],["dc.contributor.author","Steger, K."],["dc.date.accessioned","2022-10-06T13:35:15Z"],["dc.date.available","2022-10-06T13:35:15Z"],["dc.date.issued","2007"],["dc.identifier.doi","10.1093/molehr/gam064"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/116045"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.eissn","1460-2407"],["dc.relation.issn","1360-9947"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","Kruppel-like factor 4 expression in normal and pathological human testes"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2398"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Leukemia"],["dc.bibliographiccitation.lastpage","2406"],["dc.bibliographiccitation.volume","31"],["dc.contributor.author","Hehlmann, R."],["dc.contributor.author","Lauseker, M."],["dc.contributor.author","Saußele, S."],["dc.contributor.author","Pfirrmann, M."],["dc.contributor.author","Krause, S."],["dc.contributor.author","Kolb, H. J."],["dc.contributor.author","Neubauer, A."],["dc.contributor.author","Hossfeld, D. K."],["dc.contributor.author","Nerl, C."],["dc.contributor.author","Gratwohl, A."],["dc.contributor.author","Baerlocher, G. M."],["dc.contributor.author","Heim, D."],["dc.contributor.author","Brümmendorf, T. H."],["dc.contributor.author","Fabarius, A."],["dc.contributor.author","Haferlach, C."],["dc.contributor.author","Schlegelberger, B."],["dc.contributor.author","Müller, M. C."],["dc.contributor.author","Jeromin, S."],["dc.contributor.author","Proetel, U."],["dc.contributor.author","Kohlbrenner, K."],["dc.contributor.author","Voskanyan, A."],["dc.contributor.author","Rinaldetti, S."],["dc.contributor.author","Seifarth, W."],["dc.contributor.author","Spieß, B."],["dc.contributor.author","Balleisen, L."],["dc.contributor.author","Goebeler, M. C."],["dc.contributor.author","Hänel, M."],["dc.contributor.author","Ho, A."],["dc.contributor.author","Dengler, J."],["dc.contributor.author","Falge, C."],["dc.contributor.author","Kanz, L."],["dc.contributor.author","Kremers, S."],["dc.contributor.author","Burchert, A."],["dc.contributor.author","Kneba, M."],["dc.contributor.author","Stegelmann, F."],["dc.contributor.author","Köhne, C.A."],["dc.contributor.author","Lindemann, H. W."],["dc.contributor.author","Waller, C. F."],["dc.contributor.author","Pfreundschuh, M."],["dc.contributor.author","Spiekermann, K."],["dc.contributor.author","Berdel, W. E."],["dc.contributor.author","Müller, L."],["dc.contributor.author","Edinger, M."],["dc.contributor.author","Mayer, J."],["dc.contributor.author","Beelen, D. W."],["dc.contributor.author","Bentz, M."],["dc.contributor.author","Link, H."],["dc.contributor.author","Hertenstein, B."],["dc.contributor.author","Fuchs, R."],["dc.contributor.author","Wernli, M."],["dc.contributor.author","Schlegel, F."],["dc.contributor.author","Schlag, R."],["dc.contributor.author","de Wit, M."],["dc.contributor.author","Trümper, L."],["dc.contributor.author","Hebart, H."],["dc.contributor.author","Hahn, M."],["dc.contributor.author","Thomalla, J."],["dc.contributor.author","Scheid, C."],["dc.contributor.author","Schafhausen, P."],["dc.contributor.author","Verbeek, W."],["dc.contributor.author","Eckart, M. J."],["dc.contributor.author","Gassmann, W."],["dc.contributor.author","Pezzutto, A."],["dc.contributor.author","Schenk, M."],["dc.contributor.author","Brossart, P."],["dc.contributor.author","Geer, T."],["dc.contributor.author","Bildat, S."],["dc.contributor.author","Schäfer, E."],["dc.contributor.author","Hochhaus, A."],["dc.contributor.author","Hasford, J."],["dc.date.accessioned","2019-11-25T13:09:15Z"],["dc.date.accessioned","2021-10-27T13:21:33Z"],["dc.date.available","2019-11-25T13:09:15Z"],["dc.date.available","2021-10-27T13:21:33Z"],["dc.date.issued","2017"],["dc.description.abstract","Chronic myeloid leukemia (CML)-study IV was designed to explore whether treatment with imatinib (IM) at 400 mg/day (n=400) could be optimized by doubling the dose (n=420), adding interferon (IFN) (n=430) or cytarabine (n=158) or using IM after IFN-failure (n=128). From July 2002 to March 2012, 1551 newly diagnosed patients in chronic phase were randomized into a 5-arm study. The study was powered to detect a survival difference of 5% at 5 years. After a median observation time of 9.5 years, 10-year overall survival was 82%, 10-year progression-free survival was 80% and 10-year relative survival was 92%. Survival between IM400 mg and any experimental arm was not different. In a multivariate analysis, risk group, major-route chromosomal aberrations, comorbidities, smoking and treatment center (academic vs other) influenced survival significantly, but not any form of treatment optimization. Patients reaching the molecular response milestones at 3, 6 and 12 months had a significant survival advantage. For responders, monotherapy with IM400 mg provides a close to normal life expectancy independent of the time to response. Survival is more determined by patients' and disease factors than by initial treatment selection. Although improvements are also needed for refractory disease, more life-time can currently be gained by carefully addressing non-CML determinants of survival."],["dc.identifier.doi","10.1038/leu.2017.253"],["dc.identifier.isbn","28804124"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/16719"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/92031"],["dc.language.iso","en"],["dc.notes.intern","Migrated from goescholar"],["dc.relation.eissn","1476-5551"],["dc.relation.issn","1476-5551"],["dc.relation.issn","0887-6924"],["dc.relation.orgunit","Universitätsmedizin Göttingen"],["dc.rights","CC BY-NC-ND 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc-nd/4.0"],["dc.subject.ddc","610"],["dc.title","Assessment of imatinib as first-line treatment of chronic myeloid leukemia: 10-year survival results of the randomized CML study IV and impact of non-CML determinants"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","99"],["dc.bibliographiccitation.journal","New microbes and new infections"],["dc.bibliographiccitation.lastpage","102"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Seugendo, M."],["dc.contributor.author","Mshana, S. E."],["dc.contributor.author","Hokororo, A."],["dc.contributor.author","Okamo, B."],["dc.contributor.author","Mirambo, M. M."],["dc.contributor.author","von Müller, L."],["dc.contributor.author","Gunka, K."],["dc.contributor.author","Zimmermann, O."],["dc.contributor.author","Groß, U."],["dc.date.accessioned","2019-07-09T11:42:36Z"],["dc.date.available","2019-07-09T11:42:36Z"],["dc.date.issued","2015-11-01"],["dc.description.abstract","Little is known regarding the epidemiology Clostridium difficile in developing countries. Fresh stool samples from patients with diarrhoea were cultured anaerobically. C. difficile was detected in nine (6.4%) of 141 (95% confidence interval 4.2-13.1), of which seven (77.8%) were from children. HIV infection, prolonged hospitalization and antibiotic use were independent factors associated with the occurrence of C. difficile in the gastrointestinal tract. Two of the toxigenic isolates were typed as ribotype 045, and the other two had unknown ribotype. All C. difficile isolates were susceptible to metronidazole, moxifloxacin and clarithromycin, while three isolates were resistant to clarithromycin. C. difficile may be an important pathogen causing diarrhoea in sub-Saharan Africa among immunocompromised patients."],["dc.identifier.doi","10.1016/j.nmni.2015.09.016"],["dc.identifier.fs","617714"],["dc.identifier.pmid","26649183"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/13602"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/58705"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","2052-2975"],["dc.rights","CC BY-NC-ND 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc-nd/4.0"],["dc.title","Clostridium difficile infections among adults and children in Mwanza/Tanzania: is it an underappreciated pathogen among immunocompromised patients in sub-Saharan Africa?"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","111"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Journal of Medical Primatology"],["dc.bibliographiccitation.lastpage","119"],["dc.bibliographiccitation.volume","40"],["dc.contributor.author","Müller, T."],["dc.contributor.author","Hupfeld, T."],["dc.contributor.author","Roessler, J."],["dc.contributor.author","Simoni, M."],["dc.contributor.author","Gromoll, J."],["dc.contributor.author","Behr, R."],["dc.date.accessioned","2022-10-06T13:25:19Z"],["dc.date.available","2022-10-06T13:25:19Z"],["dc.date.issued","2010"],["dc.identifier.doi","10.1111/j.1600-0684.2010.00453.x"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/114809"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.issn","0047-2565"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","Molecular cloning and functional characterization of endogenous recombinant common marmoset monkey (Callithrix jacchus) follicle-stimulating hormone"],["dc.title.alternative","Characterization of recombinant marmoset FSH"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1359"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Human Reproduction"],["dc.bibliographiccitation.lastpage","1372"],["dc.bibliographiccitation.volume","24"],["dc.contributor.author","Muller, T."],["dc.contributor.author","Fleischmann, G."],["dc.contributor.author","Eildermann, K."],["dc.contributor.author","Matz-Rensing, K."],["dc.contributor.author","Horn, P. A."],["dc.contributor.author","Sasaki, E."],["dc.contributor.author","Behr, R."],["dc.date.accessioned","2022-10-06T13:34:56Z"],["dc.date.available","2022-10-06T13:34:56Z"],["dc.date.issued","2009"],["dc.identifier.doi","10.1093/humrep/dep012"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/116014"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.eissn","1460-2350"],["dc.relation.issn","0268-1161"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","A novel embryonic stem cell line derived from the common marmoset monkey (Callithrix jacchus) exhibiting germ cell-like characteristics"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]