Große, Lena

[["dc.bibliographiccitation.artnumber","PII S0098-8472(02)00069-2"],["dc.bibliographiccitation.firstpage","181"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Environmental and Experimental Botany"],["dc.bibliographiccitation.lastpage","191"],["dc.bibliographiccitation.volume","49"],["dc.contributor.author","Hauck, M."],["dc.contributor.author","Paul, A."],["dc.contributor.author","Gross, S."],["dc.contributor.author","Raubuch, M."],["dc.date.accessioned","2018-11-07T10:39:44Z"],["dc.date.available","2018-11-07T10:39:44Z"],["dc.date.issued","2003"],["dc.description.abstract","Concentrations of chlorophylls a and b decreased with increasing MnCl2 supply in the zepiphytic lichen Hypogymnia physodes, but not in Lecanora conizaeoides. The reduction of chlorophyll concentrations in. H. physodes was as strong (chlorophyll a) or even; stronger (chlorophyll b) as in samples treated with CuCl2. FeCl3 compensated for MnCl2-induced chlorophyll degradation in H. physodes. Furthermore, MnCl2-induced growth inhibition of soredia cultivated on agar plates was alleviated by FeCl3. These results suggest that Mn causes intra cellular Fe deficiency in H. physodes. A soredia growth test with MnCl2 and KCl in combination proved that mitigating effects of FeCl3 were not just caused by reduced chemical activity of Mn2+ due to the addition of another salt. Furthermore, the test showed that Cl- did not inhibit soredia growth. High FeCl3 concentrations applied alone or in combination with MnCl2 were even more detrimental to H. physodes than MnCl2. MnCl2 did not affect the concentrations of ATP, ADP and AMP in H. physodes. This suggests that Mn uptake does not induce intracellular P deficiency in H. physodes despite that Mn is known to be immobilized with P in H. physodes in intracellular polyphosphate granules and in extracellular encrustations. (C) 2002 Elsevier Science B.V. All rights reserved."],["dc.identifier.doi","10.1016/S0098-8472(02)00069-2"],["dc.identifier.isi","000181663200008"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/46120"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Pergamon-elsevier Science Ltd"],["dc.relation.issn","0098-8472"],["dc.title","Manganese toxicity in epiphytic lichens: chlorophyll degradation and interaction with iron and phosphorus"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","174"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Genomics"],["dc.bibliographiccitation.lastpage","183"],["dc.bibliographiccitation.volume","65"],["dc.contributor.author","Farber, C."],["dc.contributor.author","Gross, S."],["dc.contributor.author","Neesen, J."],["dc.contributor.author","Buiting, K."],["dc.contributor.author","Horsthemke, B."],["dc.date.accessioned","2018-11-07T08:35:47Z"],["dc.date.available","2018-11-07T08:35:47Z"],["dc.date.issued","2000"],["dc.description.abstract","Prader-Willi syndrome (PWS) results from the loss of paternal contributions for a 2-Mb imprinted region on the proximal long arm of human chromosome 15. Hitherto,five paternally active genes have been identified in this region (ZNF127, NDN, MAGEL2, SNURF-SNRPN, and IPW). Here we report the identification of a novel gene in the PWS critical region, which has been designated \"chromosome 15 open reading frame 2\" (C15orf2). C15orf2 is an intronless gene located between MAGEL2 and SNURF-SNRPN. It is associated with a CpG island, which is methylated in all tissues tested except for germ cells. C15orf2 is transcribed as a 7.5-kb mRNA and contains an open reading frame encoding a predicted 1156-amino-acid protein of unknown function. Transcription of C15orf2 occurs exclusively in the testis, and in adult testis samples, we observed biallelic expression. By zoo-blot analysis, we found related sequences in DNA from other primates, but not in nonprimate DNA. We conclude that C15orf2 may play a role in primate spermatogenesis. (C) 2000 Academic Press."],["dc.identifier.doi","10.1006/geno.2000.6158"],["dc.identifier.isi","000086972800011"],["dc.identifier.pmid","10783265"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/18157"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Academic Press Inc"],["dc.relation.issn","0888-7543"],["dc.title","Identification of a testis-specific gene (C15orf2) in the Prader-Willi syndrome region on chromosome 15"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","402"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","EMBO Journal"],["dc.bibliographiccitation.lastpage","413"],["dc.bibliographiccitation.volume","35"],["dc.contributor.author","Große, Lena"],["dc.contributor.author","Wurm, Christian Andreas"],["dc.contributor.author","Brüser, Christian"],["dc.contributor.author","Neumann, Daniel"],["dc.contributor.author","Jans, Daniel C."],["dc.contributor.author","Jakobs, Stefan"],["dc.date.accessioned","2017-09-07T11:54:38Z"],["dc.date.available","2017-09-07T11:54:38Z"],["dc.date.issued","2016"],["dc.description.abstract","The Bcl-2 family proteins Bax and Bak are essential for the execution of many apoptotic programs. During apoptosis, Bax translocates to the mitochondria and mediates the permeabilization of the outer membrane, thereby facilitating the release of pro-apoptotic proteins. Yet the mechanistic details of the Bax-induced membrane permeabilization have so far remained elusive. Here, we demonstrate that activated Bax molecules, besides forming large and compact clusters, also assemble, potentially with other proteins including Bak, into ring-like structures in the mitochondrial outer membrane. STED nanoscopy indicates that the area enclosed by a Bax ring is devoid of mitochondrial outer membrane proteins such as Tom20, Tom22, and Sam50. This strongly supports the view that the Bax rings surround an opening required for mitochondrial outer membrane permeabilization (MOMP). Even though these Bax assemblies may be necessary for MOMP, we demonstrate that at least in Drp1 knockdown cells, these assemblies are not sufficient for full cytochrome c release. Together, our super-resolution data provide direct evidence in support of large Bax-delineated pores in the mitochondrial outer membrane as being crucial for Bax-mediated MOMP in cells."],["dc.identifier.doi","10.15252/embj.201592789"],["dc.identifier.gro","3141728"],["dc.identifier.isi","000370346400005"],["dc.identifier.pmid","26783364"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14032"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/413"],["dc.language.iso","en"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.relation.eissn","1460-2075"],["dc.relation.issn","0261-4189"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Bax assembles into large ring-like structures remodeling the mitochondrial outer membrane in apoptosis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","127"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Flora"],["dc.bibliographiccitation.lastpage","131"],["dc.bibliographiccitation.volume","198"],["dc.contributor.author","Hauck, M."],["dc.contributor.author","Gross, S."],["dc.date.accessioned","2018-11-07T10:42:24Z"],["dc.date.available","2018-11-07T10:42:24Z"],["dc.date.issued","2003"],["dc.description.abstract","Samples of the foliose epiphytic lichen Hypogymnia physodes were incubated with 0, 100, 500, and 1000 muM KCl solution for up to 120 min. K was absorbed by H. physodes only in single replicates of the most highly concentrated solutions. Otherwise a release of K of up to 26 mumol g(-1) d. wt. was observed. This can be attributed to the low affinity of K for the cation exchange sites in lichen cell walls. The K concentrations applied with the incubation medium correspond to concentrations found in stemflow from dieback-affected Picea abies forests in the Harz Mountains, northern Germany. The results suggest that stemflow is not a major source of K for H. physodes. The loss of K in the present experiment could be due to changes of the water content in the lichen thalli or due to membrane damage caused by S or heavy metals in the field."],["dc.identifier.doi","10.1078/0367-2530-00084"],["dc.identifier.isi","000182322400006"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/46788"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Gmbh, Urban & Fischer Verlag"],["dc.relation.issn","0367-2530"],["dc.title","Potassium uptake in the epiphytic lichen Hypogymnia physodes at concentrations and pH conditions as found in stemflow"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","393"],["dc.bibliographiccitation.journal","Journal of Zoology"],["dc.bibliographiccitation.lastpage","399"],["dc.bibliographiccitation.volume","263"],["dc.contributor.author","Ganzhorn, J. U."],["dc.contributor.author","Pietsch, Torsten"],["dc.contributor.author","Fietz, J."],["dc.contributor.author","Gross, S."],["dc.contributor.author","Schmid, J."],["dc.contributor.author","Steiner, N."],["dc.date.accessioned","2018-11-07T10:46:55Z"],["dc.date.available","2018-11-07T10:46:55Z"],["dc.date.issued","2004"],["dc.description.abstract","Monomorphic lemurs of Madagascar allow us to investigate whether there are behavioural mechanisms that compensate for sex-specific differences in the costs of maintenance and reproduction in arboreal primates. Food selection of the pair-living Lepilemur ruficaudatus was studied in relation to food chemistry, and travel distances were measured as possible indications of differential investment in ranging activities (possibly related to the defence of territories and/or mating opportunities). Fourteen females and 14 males were radio-tracked for a total of 365 half-nights (from dusk to midnight or from midnight to dawn) at different times of the year (birth, lactation and weaning, pre-mating, post-mating). When based on monthly means, the two sexes did not differ in nightly travel distances. Food selection of females and males did not differ in relation to the chemical composition of leaves, but fruits consumed by females had lower fibre contents than fruits consumed by males. Even though other behavioural data are fragmentary, little evidence exists for behavioural mechanisms in L. ruficaudatus to compensate for the different energetic costs of females and males."],["dc.identifier.doi","10.1017/S0952836904005394"],["dc.identifier.isi","000223323200007"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/47850"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","0952-8369"],["dc.title","Selection of food and ranging behaviour in a sexually monomorphic folivorous lemur: Lepilemur ruficaudatus"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","816"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Applied Microbiology and Biotechnology"],["dc.bibliographiccitation.lastpage","822"],["dc.bibliographiccitation.volume","72"],["dc.contributor.author","Wang, L."],["dc.contributor.author","Grosse, T."],["dc.contributor.author","Stevens, H."],["dc.contributor.author","Brinkhoff, T."],["dc.contributor.author","Simon, M."],["dc.contributor.author","Liang, L."],["dc.contributor.author","Bitzer, J."],["dc.contributor.author","Bach, G."],["dc.contributor.author","Zeeck, Axel"],["dc.contributor.author","Tokuda, H."],["dc.contributor.author","Lang, S."],["dc.date.accessioned","2018-11-07T09:08:24Z"],["dc.date.available","2018-11-07T09:08:24Z"],["dc.date.issued","2006"],["dc.description.abstract","The new marine Halomonas sp. strain GWS-BW-H8hM (DSM 17996) was found to produce 3-(4'-hydroxyphenyl)-4-phenylpyrrole-2,5-dicarboxylic acid (HPPD-1) and 3,4-bis(4'-hydroxy- phenyl)pyrrole-2,5-dicarboxylic acid (HPPD-2). In initial cultivations using marine broth, only low contents of these compounds have been isolated. Improving the conditions and growing the strain on artificial seawater supplemented with tryptone 10 g l(-1), yeast extract 5 g l(-1), L-tyrosine 0.6 g l(-1), glycine 1 g l(-1), and glucose 6 g l(-1), the growth-associated HPPD-1 and HPPD-2 production of a 40-l batch cultivation reached the amounts of 47 mg l(-1)supercript stop and 116 mg l(-1), respectively, after 65 h. Both compounds showed potent anti-tumor-promoting activities."],["dc.identifier.doi","10.1007/s00253-006-0370-1"],["dc.identifier.isi","000240809600027"],["dc.identifier.pmid","16642332"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/26023"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0175-7598"],["dc.title","Bioactive hydroxyphenylpyrrole-dicarboxylic acids from a new marine Halomonas sp.: production and structure elucidation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","78"],["dc.bibliographiccitation.journal","Tropical Medicine & International Health"],["dc.bibliographiccitation.lastpage","79"],["dc.bibliographiccitation.volume","16"],["dc.contributor.author","Gross, L."],["dc.contributor.author","Zimmermann, Ortrud"],["dc.contributor.author","Kassimova, Iparkhan"],["dc.contributor.author","de Ciman, Ring"],["dc.contributor.author","Amuzu, Sylvarius K."],["dc.contributor.author","Schulze, M."],["dc.contributor.author","Stich, August"],["dc.contributor.author","Gross, U."],["dc.date.accessioned","2018-11-07T08:51:11Z"],["dc.date.available","2018-11-07T08:51:11Z"],["dc.date.issued","2011"],["dc.identifier.isi","000295519100221"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/21872"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Malden"],["dc.relation.issn","1360-2276"],["dc.title","Epidemiology of bacterial blood-stream infections in a rural African setting before and after the introduction of ciprofloxacin"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","86"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","The Journal of Antibiotics"],["dc.bibliographiccitation.lastpage","92"],["dc.bibliographiccitation.volume","59"],["dc.contributor.author","Bitzer, J."],["dc.contributor.author","Grosse, T."],["dc.contributor.author","Wang, L."],["dc.contributor.author","Lang, S."],["dc.contributor.author","Beil, W."],["dc.contributor.author","Zeeck, Axel"],["dc.date.accessioned","2018-11-07T10:22:55Z"],["dc.date.available","2018-11-07T10:22:55Z"],["dc.date.issued","2006"],["dc.description.abstract","The addition of anthranilic acid to the culture medium of the marine derived Halomonas sp. strain GWS-BW-H8hM completely altered the secondary metabolite pattern relative to the standard conditions. The red-orange color of the culture filtrate extract was the result of the production of 2-aminophenoxazin-3-one (1), chandrananimycin C (5) and three new derivatives of 1 with a previously unknown substitution pattern: 2-amino-, 2-amino-S-benzoyl-, and 2-amino-8-(4-hydroxybenzoyl)-6-hydroxyphenoxazin-3 -one (2 similar to 4). The compounds were determined to have antibacterial and cytotoxic activities; a mode of action other than DNA intercalation is discussed."],["dc.identifier.isi","000235791600003"],["dc.identifier.pmid","16629408"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/42357"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Japan Antibiotics Research Assoc"],["dc.relation.issn","0021-8820"],["dc.title","New aminophenoxazinones from a marine Halomonas sp.: Fermentation, structure elucidation, and biological activity"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]