Now showing 1 - 10 of 11
  • 2018Journal Article
    [["dc.bibliographiccitation.firstpage","509"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Brain Stimulation"],["dc.bibliographiccitation.lastpage","517"],["dc.bibliographiccitation.volume","11"],["dc.contributor.author","de Lara, Gabriel Amador"],["dc.contributor.author","Alekseichuk, Ivan"],["dc.contributor.author","Turi, Zsolt"],["dc.contributor.author","Lehr, Albert"],["dc.contributor.author","Antal, Andrea"],["dc.contributor.author","Paulus, Walter"],["dc.date.accessioned","2018-10-10T10:23:09Z"],["dc.date.available","2018-10-10T10:23:09Z"],["dc.date.issued","2018"],["dc.description.abstract","Phase-amplitude cross-frequency coupling (PAC) is characterized by the modulation of the power of a fast brain oscillation (e.g., gamma) by the phase of a slow rhythm (e.g., theta). PAC in different sub- and neocortical regions is known to underlie effective neural communication and correlates with successful long-term memory formation."],["dc.identifier.doi","10.1016/j.brs.2017.12.007"],["dc.identifier.pmid","29317186"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/15940"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.issn","1876-4754"],["dc.relation.issn","1935-861X"],["dc.title","Perturbation of theta-gamma coupling at the temporal lobe hinders verbal declarative memory"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2016Journal Article
    [["dc.bibliographiccitation.firstpage","1513"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","Current Biology"],["dc.bibliographiccitation.lastpage","1521"],["dc.bibliographiccitation.volume","26"],["dc.contributor.author","Alekseichuk, Ivan"],["dc.contributor.author","Turi, Zsolt"],["dc.contributor.author","Amador de Lara, Gabriel"],["dc.contributor.author","Antal, Andrea"],["dc.contributor.author","Paulus, Walter J."],["dc.date.accessioned","2018-11-07T10:12:41Z"],["dc.date.available","2018-11-07T10:12:41Z"],["dc.date.issued","2016"],["dc.description.abstract","Previous, albeit correlative, findings have shown that the neural mechanisms underlying working memory critically require cross-structural and cross-frequency coupling mechanisms between theta and gamma neural oscillations. However, the direct causality between cross-frequency coupling and working memory performance remains to be demonstrated. Here we externally modulated the interaction of theta and gamma rhythms in the prefrontal cortex using novel cross-frequency protocols of transcranial alternating current stimulation to affect spatial working memory performance in humans. Enhancement of working memory performance and increase of global neocortical connectivity were observed when bursts of high gamma oscillations (80-100 Hz) coincided with the peaks of the theta waves, whereas superimposition on the trough of the theta wave and low gamma frequency protocols were ineffective. Thus, our results demonstrate the sensitivity of working memory performance and global neocortical connectivity to the phase and rhythm of the externally driven theta gamma cross-frequency synchronization."],["dc.description.sponsorship","Deutsche Forschungsgemeinschaft [SPP 1665]"],["dc.identifier.doi","10.1016/j.cub.2016.04.035"],["dc.identifier.isi","000378661800014"],["dc.identifier.pmid","27238283"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/40288"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.notes.submitter","Najko"],["dc.relation.issn","1879-0445"],["dc.relation.issn","0960-9822"],["dc.title","Spatial Working Memory in Humans Depends on Theta and High Gamma Synchronization in the Prefrontal Cortex"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]
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  • 2017Journal Article
    [["dc.bibliographiccitation.firstpage","147"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Restorative Neurology and Neuroscience"],["dc.bibliographiccitation.lastpage","158"],["dc.bibliographiccitation.volume","35"],["dc.contributor.author","Alekseichuk, Ivan"],["dc.contributor.author","Pabel, Stefanie Corinna"],["dc.contributor.author","Antal, Andrea"],["dc.contributor.author","Paulus, Walter J."],["dc.date.accessioned","2020-12-10T18:44:14Z"],["dc.date.available","2020-12-10T18:44:14Z"],["dc.date.issued","2017"],["dc.description.abstract","Background: There is a growing interest in large-scale connectivity as one of the crucial factors in working memory. Correlative evidence has revealed the anatomical and electrophysiological players in the working memory network, but understanding of the effective role of their connectivity remains elusive. Objective: In this double-blind, placebo-controlled study we aimed to identify the causal role of theta phase connectivity in visual-spatial working memory. Methods: The frontoparietal network was over-or de-synchronized in the anterior-posterior direction by multi-electrode, 6Hz transcranial alternating current stimulation (tACS). Results: A decrease in memory performance and increase in reaction time was caused by frontoparietal intrahemispheric desynchronization. According to the diffusion drift model, this originated in a lower signal-to-noise ratio, known as the drift rate index, in the memory system. The EEG analysis revealed a corresponding decrease in phase connectivity between prefrontal and parietal areas after tACS-driven desynchronization. The over-synchronization did not result in any changes in either the behavioral or electrophysiological levels in healthy participants. Conclusion: Taken together, we demonstrate the feasibility of manipulating multi-site large-scale networks in humans, and the disruptive effect of frontoparietal desynchronization on theta phase connectivity and visual-spatial working memory."],["dc.identifier.doi","10.3233/RNN-160714"],["dc.identifier.eissn","1878-3627"],["dc.identifier.isi","000398131700002"],["dc.identifier.issn","0922-6028"],["dc.identifier.pmid","28059806"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78377"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Ios Press"],["dc.relation.issn","1878-3627"],["dc.relation.issn","0922-6028"],["dc.title","Intrahemispheric theta rhythm desynchronization impairs working memory"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2020Journal Article
    [["dc.bibliographiccitation.firstpage","474"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Brain Stimulation"],["dc.bibliographiccitation.lastpage","483"],["dc.bibliographiccitation.volume","13"],["dc.contributor.author","Alekseichuk, Ivan"],["dc.contributor.author","Turi, Zsolt"],["dc.contributor.author","Veit, Sibel"],["dc.contributor.author","Paulus, Walter"],["dc.date.accessioned","2020-12-10T14:22:49Z"],["dc.date.available","2020-12-10T14:22:49Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1016/j.brs.2019.12.019"],["dc.identifier.issn","1935-861X"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/71742"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Model-driven neuromodulation of the right posterior region promotes encoding of long-term memories"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2016Journal Article
    [["dc.bibliographiccitation.firstpage","110"],["dc.bibliographiccitation.journal","NeuroImage"],["dc.bibliographiccitation.lastpage","117"],["dc.bibliographiccitation.volume","140"],["dc.contributor.author","Alekseichuk, Ivan"],["dc.contributor.author","Diers, Kersten"],["dc.contributor.author","Paulus, Walter J."],["dc.contributor.author","Antal, Andrea"],["dc.date.accessioned","2018-11-07T10:08:07Z"],["dc.date.available","2018-11-07T10:08:07Z"],["dc.date.issued","2016"],["dc.description.abstract","The aim of this study was to investigate if the blood oxygenation level-dependent (BOLD) changes in the visual cortex can be used as biomarkers reflecting the online and offline effects of transcranial electrical stimulation (tES). Anodal transcranial direct current stimulation (tDCS) and 10 Hz transcranial alternating current stimulation (tACS) were applied for 10 min duration over the occipital cortex of healthy adults during the presentation of different visual stimuli, using a crossover, double-blinded design. Control experiments were also performed, in which sham stimulation as well as another electrode montage were used. Anodal tDCS over the visual cortex induced a small but significant further increase in BOLD response evoked by a visual stimulus; however, no aftereffect was observed. Ten hertz of tACS did not result in an online effect, but in a wide spread offline BOLD decrease over the occipital, temporal, and frontal areas. These findings demonstrate that tES during visual perception affects the neuronal metabolism, which can be detected with functional magnetic resonance imaging (fMRI). (C) 2016 Elsevier Inc. All rights reserved."],["dc.description.sponsorship","DFG [PA 419/15-1]"],["dc.identifier.doi","10.1016/j.neuroimage.2015.11.034"],["dc.identifier.isi","000384071900013"],["dc.identifier.pmid","26608246"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/39408"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Academic Press Inc Elsevier Science"],["dc.relation.issn","1095-9572"],["dc.relation.issn","1053-8119"],["dc.title","Transcranial electrical stimulation of the occipital cortex during visual perception modifies the magnitude of BOLD activity: A combined tES-fMRI approach"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2019Journal Article
    [["dc.bibliographiccitation.firstpage","65"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Cognitive Processing"],["dc.bibliographiccitation.lastpage","76"],["dc.bibliographiccitation.volume","21"],["dc.contributor.author","Cattaneo, Zaira"],["dc.contributor.author","Ferrari, Chiara"],["dc.contributor.author","Schiavi, Susanna"],["dc.contributor.author","Alekseichuk, Ivan"],["dc.contributor.author","Antal, Andrea"],["dc.contributor.author","Nadal, Marcos"],["dc.date.accessioned","2020-12-10T14:11:16Z"],["dc.date.available","2020-12-10T14:11:16Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1007/s10339-019-00936-9"],["dc.identifier.eissn","1612-4790"],["dc.identifier.issn","1612-4782"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/71027"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Medial prefrontal cortex involvement in aesthetic appreciation of paintings: a tDCS study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2015Conference Abstract
    [["dc.bibliographiccitation.journal","Journal of the Neurological Sciences"],["dc.bibliographiccitation.volume","357"],["dc.contributor.author","Paulus, Walter J."],["dc.contributor.author","Alekseichuk, Ivan"],["dc.contributor.author","Antal, Andrea"],["dc.date.accessioned","2018-11-07T09:50:10Z"],["dc.date.available","2018-11-07T09:50:10Z"],["dc.date.issued","2015"],["dc.format.extent","E247"],["dc.identifier.doi","10.1016/j.jns.2015.08.862"],["dc.identifier.isi","000384634801192"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/35655"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Bv"],["dc.publisher.place","Amsterdam"],["dc.relation.conference","22nd World Congress of Neurology (WCN)"],["dc.relation.eventlocation","Santiago, CHILE"],["dc.relation.issn","1878-5883"],["dc.relation.issn","0022-510X"],["dc.title","Tacs in theta range improves the hit rate and general accuracy in a spatial working memory task"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2015Journal Article
    [["dc.bibliographiccitation.artnumber","e0123085"],["dc.bibliographiccitation.firstpage","1"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","PLOS ONE"],["dc.bibliographiccitation.lastpage","17"],["dc.bibliographiccitation.volume","10"],["dc.contributor.author","Pisoni, Alberto"],["dc.contributor.author","Turi, Zsolt"],["dc.contributor.author","Raithel, Almuth"],["dc.contributor.author","Ambrus, Géza Gergely"],["dc.contributor.author","Alekseichuk, Ivan"],["dc.contributor.author","Schacht, Annekathrin"],["dc.contributor.author","Paulus, Walter"],["dc.contributor.author","Antal, Andrea"],["dc.date.accessioned","2017-09-07T11:53:43Z"],["dc.date.available","2017-09-07T11:53:43Z"],["dc.date.issued","2015"],["dc.description.abstract","There is emerging evidence from imaging studies that parietal and temporal cortices act together to achieve successful recognition of declarative information; nevertheless, the precise role of these regions remains elusive. To evaluate the role of these brain areas in declarative memory retrieval, we applied bilateral tDCS, with anode over the left and cathode over the right parietal or temporal cortices separately, during the recognition phase of a verbal learning paradigm using a balanced old-new decision task. In a parallel group design, we tested three different groups of healthy adults, matched for demographic and neurocognitive status: two groups received bilateral active stimulation of either the parietal or the temporal cortex, while a third group received sham stimulation. Accuracy, discriminability index (d’) and reaction times of recognition memory performance were measurements of interest. The d’ sensitivity index and accuracy percentage improved in both active stimulation groups, as compared with the sham one, while reaction times remained unaffected. Moreover, the analysis of accuracy revealed a different effect of tDCS for old and new item recognition. While the temporal group showed enhanced performance for old item recognition, the parietal group was better at correctly recognising new ones. Our results support an active role of both of these areas in memory retrieval, possibly underpinning different stages of the recognition process."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2015"],["dc.identifier.doi","10.1371/journal.pone.0123085"],["dc.identifier.gro","3151348"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/11758"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/8142"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","final"],["dc.notes.submitter","chake"],["dc.relation.issn","1932-6203"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Separating Recognition Processes of Declarative Memory via Anodal tDCS: Boosting Old Item Recognition by Temporal and New Item Detection by Parietal Stimulation"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.peerReviewed","no"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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  • 2017Journal Article
    [["dc.bibliographiccitation.firstpage","e289"],["dc.bibliographiccitation.journal","Sleep Medicine"],["dc.bibliographiccitation.volume","40"],["dc.contributor.author","Sakellariou, D."],["dc.contributor.author","Higgins, S."],["dc.contributor.author","Beniczky, S."],["dc.contributor.author","Gildeh, N."],["dc.contributor.author","Alekseichuk, I."],["dc.contributor.author","Drakatos, P."],["dc.contributor.author","Murphy, P.B."],["dc.contributor.author","Kent, B."],["dc.contributor.author","Nesbitt, A."],["dc.contributor.author","Williams, A.J."],["dc.contributor.author","Kryger, M."],["dc.contributor.author","Goadsby, P.J."],["dc.contributor.author","Richardson, M."],["dc.contributor.author","Leschziner, G.D."],["dc.contributor.author","Rosenzweig, I."],["dc.date.accessioned","2020-12-10T15:21:18Z"],["dc.date.available","2020-12-10T15:21:18Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1016/j.sleep.2017.11.849"],["dc.identifier.issn","1389-9457"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/72979"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Exploding head syndrome: a co-activation of alpha-frequency band oscillations as a novel interictal fingerprint?"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2018Journal Article
    [["dc.bibliographiccitation.artnumber","e2005867"],["dc.bibliographiccitation.firstpage","1"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","PLoS Biology"],["dc.bibliographiccitation.lastpage","6"],["dc.bibliographiccitation.volume","16"],["dc.contributor.author","Turi, Zsolt"],["dc.contributor.author","Alekseichuk, Ivan"],["dc.contributor.author","Paulus, Walter"],["dc.date.accessioned","2018-10-10T09:45:00Z"],["dc.date.available","2018-10-10T09:45:00Z"],["dc.date.issued","2018"],["dc.description.abstract","The ability to simultaneously process and maintain multiple pieces of information is limited. Over the past 50 years, observational methods have provided a large amount of insight regarding the neural mechanisms that underpin the mental capacity that we refer to as \"working memory.\" More than 20 years ago, a neural coding scheme was proposed for working memory. As a result of technological developments, we can now not only observe but can also influence brain rhythms in humans. Building on these novel developments, we have begun to externally control brain oscillations in order to extend the limits of working memory."],["dc.identifier.doi","10.1371/journal.pbio.2005867"],["dc.identifier.pmid","29672569"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/15665"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/15936"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","final"],["dc.relation.issn","1545-7885"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0/"],["dc.title","On ways to overcome the magical capacity limit of working memory"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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