Now showing 1 - 10 of 66
  • 2011Journal Article
    [["dc.bibliographiccitation.firstpage","728"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz"],["dc.bibliographiccitation.lastpage","734"],["dc.bibliographiccitation.volume","54"],["dc.contributor.author","Alter, T."],["dc.contributor.author","Bereswill, S."],["dc.contributor.author","Gluender, G."],["dc.contributor.author","Haag, L.-M."],["dc.contributor.author","Haenel, I."],["dc.contributor.author","Heimesaat, Markus M."],["dc.contributor.author","Lugert, Raimond"],["dc.contributor.author","Rautenschlein, Silke"],["dc.contributor.author","Weber, R. M."],["dc.contributor.author","Zautner, Andreas Erich"],["dc.contributor.author","Gross, U."],["dc.date.accessioned","2018-11-07T08:55:46Z"],["dc.date.available","2018-11-07T08:55:46Z"],["dc.date.issued","2011"],["dc.description.abstract","Over the last few years, infections with Campylobacter have significantly increased in Europe and Germany and these bacteria have even surpassed Salmonella as the most prevalent bacteria, causing gastroenteritis. Especially contamination during the handling and consumption of meat products seems to be the most important risk factor which plays a prominent role for transmission to man. In addition, contact with pets and other animals, drinking raw or improperly pasteurized milk, and the tenacity of Campylobacter in different environments, especially water, have also to be considered for an adequate risk assessment. Besides gastroenteritis, arthralgia, and Guillain-Barre syndrome are important clinical complications of Campylobacter infections in man. At the same time, it is mostly unclear why the course of infection in man and in reservoir animals differs significantly, especially as only a few classical bacterial virulence factors have been identified so far. For these reasons, the development of efficient prevention strategies is of utmost importance in order to control campylobacteriosis."],["dc.identifier.doi","10.1007/s00103-011-1289-y"],["dc.identifier.isi","000292038500010"],["dc.identifier.pmid","21626378"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/22983"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","1436-9990"],["dc.title","Campylobacteriosis of man. Livestock as reservoir for Campylobacter species"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2010Journal Article
    [["dc.bibliographiccitation.firstpage","91"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Journal of Food Safety and Food Quality"],["dc.bibliographiccitation.lastpage","101"],["dc.bibliographiccitation.volume","61"],["dc.contributor.author","Zautner, Andreas Erich"],["dc.contributor.author","Herrmann, Sahra"],["dc.contributor.author","Gross, Uwe"],["dc.date.accessioned","2018-11-07T08:43:22Z"],["dc.date.available","2018-11-07T08:43:22Z"],["dc.date.issued","2010"],["dc.description.abstract","In recent years Campylobacter jejuni replaced Salmonella spp. as the most common bacterial cause of food-borne gastroenteritis worldwide. Noticeable is the fact that no classical enterotoxins are known for C. jejuni. The sequencing of the complete genome revealed that C. jejuni possesses one single trimeric cytotoxin, called cytolethal distending toxin (CdtABC). Other previously suspected toxins could not be confirmed by sequence analysis. However, a number of alternative virulence-associated factors have been identified so far. The multidrug efflux pump CmeABC faciliates, by \"neutralization\" of bile salts, the survival of C. jejuni in the avian as well as in the human intestine. Furthermore it is responsible for resistance to heavy metal ions and to certain antibiotics. The flagellum of C. jejuni mediates not only the targeted motility directed by three families of chemo- and aerotaxis receptors. A homologue of a type-III-secretion-system integrated in the flagellar apparatus is functionally involved in the cell-invasion process. Thus, a whole group of proteins termed Campylobacter invasion antigens (Cia) is injected into the host cell via the flagellar transport mechanism during the process of host cell invasion. Further pathogenicity-associated determinants are the polysaccharide capsule and specific glycosylation of the lipooligosaccharide (LOS). It has been shown that C. jejuni strains with sialylation of the lipooligosaccharide display increased invasiveness. These strains are also responsible for the development of the Guillain-Barre-syndrome, through molecular mimicry with gangliosides of the central nervous system. In the past, many colonization-related factors have been identified with the help of transposon-induced mutagenesis and chicken colonization models. Using this and other modern molecular biology methods, combined with appropriate animal models such as gnotobiotic mice in which symptomatic campylobacteriosis can be established, it is hoped to identify additional virulence-associated factors."],["dc.identifier.doi","10.2376/0003-925X-61-91"],["dc.identifier.isi","000280167900003"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/19946"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","M H Schaper Gmbh Co Kg"],["dc.relation.issn","0003-925X"],["dc.title","Campylobacter jejuni - The Search for virulence-associated factors"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2014Review
    [["dc.bibliographiccitation.artnumber","375681"],["dc.bibliographiccitation.journal","BioMed Research International"],["dc.contributor.author","Frickmann, Hagen"],["dc.contributor.author","Masanta, Wycliffe Omurwa"],["dc.contributor.author","Zautner, Andreas Erich"],["dc.date.accessioned","2018-11-07T09:45:32Z"],["dc.date.available","2018-11-07T09:45:32Z"],["dc.date.issued","2014"],["dc.description.abstract","Atypical and multidrug resistance, especially ESBL and carbapenemase expressing Enterobacteriaceae, is globally spreading. Therefore, it becomes increasingly difficult to achieve therapeutic success by calculated antibiotic therapy. Consequently, rapid antibiotic resistance testing is essential. Various molecular and mass spectrometry-based approaches have been introduced in diagnostic microbiology to speed up the providing of reliable resistance data. PCR- and sequencing-based approaches are the most expensive but the most frequently applied modes of testing, suitable for the detection of resistance genes even from primary material. Next generation sequencing, based either on assessment of allelic single nucleotide polymorphisms or on the detection of nonubiquitous resistance mechanisms might allow for sequence-based bacterial resistance testing comparable to viral resistance testing on the long term. Fluorescence in situ hybridization (FISH), based on specific binding of fluorescence-labeled oligonucleotide probes, provides a less expensive molecular bridging technique. It is particularly useful for detection of resistance mechanisms based on mutations in ribosomal RNA. Approaches based on MALDI-TOFMS, alone or in combination with molecular techniques, like PCR/electrospray ionization MS or minisequencing provide the fastest resistance results from pure colonies or even primary samples with a growing number of protocols. This review details the various approaches of rapid resistance testing, their pros and cons, and their potential use for the diagnostic laboratory."],["dc.description.sponsorship","Deutsche Forschungsgemeinschaft; Georg August Universitat Gottingen"],["dc.identifier.doi","10.1155/2014/375681"],["dc.identifier.isi","000346708400001"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/10892"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/34641"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Hindawi Publishing Corporation"],["dc.relation.issn","2314-6141"],["dc.relation.issn","2314-6133"],["dc.rights","CC BY 3.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/3.0"],["dc.title","Emerging Rapid Resistance Testing Methods for Clinical Microbiology Laboratories and Their Potential Impact on Patient Management"],["dc.type","review"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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  • 2012Journal Article Research Paper
    [["dc.bibliographiccitation.artnumber","1"],["dc.bibliographiccitation.journal","Otolaryngology"],["dc.bibliographiccitation.volume","5"],["dc.contributor.author","Frickmann, Hagen"],["dc.contributor.author","Zautner, Andreas Erich"],["dc.contributor.other","Ulualp, Seckin O."],["dc.date.accessioned","2013-01-04T13:06:45Z"],["dc.date.accessioned","2021-10-27T13:19:58Z"],["dc.date.available","2013-01-04T13:06:45Z"],["dc.date.available","2021-10-27T13:19:58Z"],["dc.date.issued","2012"],["dc.description.abstract","The article provides an overview on the current state-of-science of middle ear cholesteatoma, a non-neoplastic, keratinizing lesion that is characterized by the proliferation of epithelium with aberrant micro-architecture. Pathogenetic mechanisms including morphological, immunological, epidemiological and microbiological aspects of the disease are summarized. The importance of penicillinase-expressing anaerobic bacteria and biofilm formation for maintaining the chronic middle ear inflammation is stressed. Nevertheless, the role of the isolated pathogens in the primarily non-sterile compartiment of the middle ear cavity is so far not completely understood and data on the isolated species are contradictious. Heredity was demonstated for some variants of the disease. Therefore, further studies on the etiological role of microbial agents and potential benefits of resistance-adapted antimicrobial therapy seem advisable. Local and systemic complications of the potentially life-threatening disease like conductive and sensorineural hearing loss and cranial abscesses are reported. The prognosis is limited due to frequent recurrence in spite of surgical therapy. Further research is necessary for a better understanding of the pathogenetic mechanisms and to expand the sectrum of therapeutic options."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2012"],["dc.identifier.doi","10.4172/2161-119X.S5-001"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/8474"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/91926"],["dc.language.iso","en"],["dc.notes.intern","Migrated from goescholar"],["dc.relation.issn","2161-119X"],["dc.relation.orgunit","Universitätsmedizin Göttingen"],["dc.relation.orgunit","Institut für Medizinische Mikrobiologie"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.subject.ddc","610"],["dc.title","Cholesteatoma – A Potential Consequence of Chronic Middle Ear Inflammation"],["dc.title.alternative","Otilis Media"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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  • 2013Conference Abstract
    [["dc.bibliographiccitation.journal","Mycoses"],["dc.bibliographiccitation.volume","56"],["dc.contributor.author","Zautner, Andreas Erich"],["dc.contributor.author","Folba, Claudia"],["dc.contributor.author","Ichsan, Ichsan"],["dc.contributor.author","Weig, Michael S."],["dc.contributor.author","Gross, U."],["dc.contributor.author","Bader, Oliver"],["dc.date.accessioned","2018-11-07T09:20:59Z"],["dc.date.available","2018-11-07T09:20:59Z"],["dc.date.issued","2013"],["dc.format.extent","5"],["dc.identifier.isi","000322918300017"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/29007"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.issn","0933-7407"],["dc.title","Mass Spectrometry as a new Tool for Subtyping in Fungi"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2017Journal Article
    [["dc.bibliographiccitation.firstpage","40"],["dc.bibliographiccitation.journal","Acta Tropica"],["dc.bibliographiccitation.lastpage","65"],["dc.bibliographiccitation.volume","165"],["dc.contributor.author","Schwarz, Norbert Georg"],["dc.contributor.author","Loderstaedt, Ulrike"],["dc.contributor.author","Hahn, Andreas"],["dc.contributor.author","Hinz, Rebecca"],["dc.contributor.author","Zautner, Andreas Erich"],["dc.contributor.author","Eibach, Daniel"],["dc.contributor.author","Fischer, Marcellus"],["dc.contributor.author","Hagen, Ralf Matthias"],["dc.contributor.author","Frickmann, Hagen"],["dc.date.accessioned","2018-11-07T10:29:30Z"],["dc.date.available","2018-11-07T10:29:30Z"],["dc.date.issued","2017"],["dc.description.abstract","This review reports on laboratory diagnostic approaches for selected, highly pathogenic neglected zoonotic diseases, i.e. anthrax, bovine tuberculosis, brucellosis, echinococcosis, leishmaniasis, rabies, Taenia solium-associated diseases (neuro-/cysticercosis & taeniasis) and trypanosomiasis. Diagnostic options, including microscopy, culture, matrix-assisted laser-desorption-ionisation time of-flight mass spectrometry, molecular approaches and serology are introduced. These procedures are critically discussed regarding their diagnostic reliability and state of evaluation. For rare diseases reliable evaluation data are scarce due to the rarity of samples. If bio-safety level 3 is required for cultural growth, but such high standards of laboratory infrastructure are not available, serological and molecular approaches from inactivated sample material might be alternatives. Multiple subsequent testing using various test platforms in a stepwise approach may improve sensitivity and specificity. Cheap and easy to use tests, usually called \"rapid diagnostic tests\" (RDTs) may impact disease control measures, but should not preclude developing countries from state of the art diagnostics. (C) 2015 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license."],["dc.identifier.doi","10.1016/j.actatropica.2015.09.003"],["dc.identifier.isi","000390973400008"],["dc.identifier.pmid","26391646"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14301"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/43653"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Elsevier Science Bv"],["dc.relation.issn","1873-6254"],["dc.relation.issn","0001-706X"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Microbiological laboratory diagnostics of neglected zoonotic diseases (NZDs)"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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  • 2019Journal Article
    [["dc.bibliographiccitation.firstpage","352"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Foodborne Pathogens and Disease"],["dc.bibliographiccitation.lastpage","358"],["dc.bibliographiccitation.volume","16"],["dc.contributor.author","Dekker, Denise"],["dc.contributor.author","Eibach, Daniel"],["dc.contributor.author","Boahen, Kennedy G."],["dc.contributor.author","Akenten, Charity Wiafe"],["dc.contributor.author","Pfeifer, Yvonne"],["dc.contributor.author","Zautner, Andreas E."],["dc.contributor.author","Mertens, Eva"],["dc.contributor.author","Krumkamp, Ralf"],["dc.contributor.author","Jaeger, Anna"],["dc.contributor.author","Flieger, Antje"],["dc.contributor.author","Owusu-Dabo, Ellis"],["dc.contributor.author","May, JĂĽrgen"],["dc.date.accessioned","2020-12-10T18:16:02Z"],["dc.date.available","2020-12-10T18:16:02Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1089/fpd.2018.2562"],["dc.identifier.eissn","1556-7125"],["dc.identifier.issn","1535-3141"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/16618"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/75032"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Fluoroquinolone-Resistant Salmonella enterica , Campylobacter spp., and Arcobacter butzleri from Local and Imported Poultry Meat in Kumasi, Ghana"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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  • 2020Journal Article
    [["dc.bibliographiccitation.firstpage","279"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Animals"],["dc.bibliographiccitation.volume","10"],["dc.contributor.author","Ushanov, Leonid"],["dc.contributor.author","Lasareishvili, Besarion"],["dc.contributor.author","Janashia, Irakli"],["dc.contributor.author","Zautner, Andreas E."],["dc.date.accessioned","2020-12-10T18:46:55Z"],["dc.date.available","2020-12-10T18:46:55Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.3390/ani10020279"],["dc.identifier.eissn","2076-2615"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/17334"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78585"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Application of Campylobacter jejuni Phages: Challenges and Perspectives"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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  • 2012Conference Abstract
    [["dc.bibliographiccitation.journal","International Journal of Medical Microbiology"],["dc.bibliographiccitation.volume","302"],["dc.contributor.author","Vu, C. H."],["dc.contributor.author","Stentzel, S."],["dc.contributor.author","Kolata, J."],["dc.contributor.author","Steil, Leif"],["dc.contributor.author","Zautner, Andreas Erich"],["dc.contributor.author","Classen, Carl Friedrich"],["dc.contributor.author","Voelker, Uwe"],["dc.contributor.author","Broeker, Barbara"],["dc.date.accessioned","2018-11-07T09:06:03Z"],["dc.date.available","2018-11-07T09:06:03Z"],["dc.date.issued","2012"],["dc.format.extent","39"],["dc.identifier.isi","000311593300132"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/25467"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Gmbh, Urban & Fischer Verlag"],["dc.publisher.place","Jena"],["dc.relation.conference","64th Annual Meeting of the German-Society-for-Hygiene-and-Microbiology (DGHM)"],["dc.relation.eventlocation","Hamburg, GERMANY"],["dc.relation.issn","1438-4221"],["dc.title","Human IgG Response to Staphylococcus aureus-Induced Furunculosis"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2012Conference Abstract
    [["dc.bibliographiccitation.firstpage","24"],["dc.bibliographiccitation.journal","International Journal of Medical Microbiology"],["dc.bibliographiccitation.lastpage","25"],["dc.bibliographiccitation.volume","302"],["dc.contributor.author","Zautner, Andreas Erich"],["dc.contributor.author","Johann, C."],["dc.contributor.author","Strubel, A."],["dc.contributor.author","Busse, C."],["dc.contributor.author","Tareen, Abdul Malik"],["dc.contributor.author","Lugert, Raimond"],["dc.contributor.author","Schmidt-Ott, Ruprecht"],["dc.contributor.author","Gross, U."],["dc.date.accessioned","2018-11-07T09:06:02Z"],["dc.date.available","2018-11-07T09:06:02Z"],["dc.date.issued","2012"],["dc.identifier.isi","000311593300082"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/25464"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Gmbh, Urban & Fischer Verlag"],["dc.publisher.place","Jena"],["dc.relation.conference","64th Annual Meeting of the German-Society-for-Hygiene-and-Microbiology (DGHM)"],["dc.relation.eventlocation","Hamburg, GERMANY"],["dc.relation.issn","1438-4221"],["dc.title","Serodiagnostic and Seroprevalence of Campylobacteriosis and post-Campylobacter-sequelae"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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