Now showing 1 - 10 of 34
  • 2020Journal Article
    [["dc.bibliographiccitation.firstpage","E16"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Neurosurgical Focus"],["dc.bibliographiccitation.volume","49"],["dc.contributor.author","Bettag, Christoph"],["dc.contributor.author","Abboud, Tammam"],["dc.contributor.author","von der Brelie, Christian"],["dc.contributor.author","Melich, Patrick"],["dc.contributor.author","Rohde, Veit"],["dc.contributor.author","Schatlo, Bawarjan"],["dc.date.accessioned","2021-04-14T08:23:53Z"],["dc.date.available","2021-04-14T08:23:53Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.3171/2020.5.FOCUS20267"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/81082"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1092-0684"],["dc.title","Do we underdiagnose osteoporosis in patients with pyogenic spondylodiscitis?"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2018Journal Article
    [["dc.bibliographiccitation.firstpage","E131"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","American Journal of Neuroradiology"],["dc.bibliographiccitation.lastpage","E131"],["dc.bibliographiccitation.volume","39"],["dc.contributor.author","Larsen, N."],["dc.contributor.author","Jansen, O."],["dc.contributor.author","Riedel, C.H."],["dc.contributor.author","von der Brelie, C."],["dc.contributor.author","FlĂĽh, C."],["dc.date.accessioned","2020-12-10T18:44:06Z"],["dc.date.available","2020-12-10T18:44:06Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.3174/ajnr.A5860"],["dc.identifier.eissn","1936-959X"],["dc.identifier.issn","0195-6108"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78329"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Reply:"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2019Journal Article
    [["dc.bibliographiccitation.firstpage","e74"],["dc.bibliographiccitation.journal","World Neurosurgery"],["dc.bibliographiccitation.lastpage","e80"],["dc.bibliographiccitation.volume","131"],["dc.contributor.author","MĂĽller, Sebastian J."],["dc.contributor.author","Freimann, Florian B."],["dc.contributor.author","von der Brelie, Christian"],["dc.contributor.author","Rohde, Veit"],["dc.contributor.author","Schatlo, Bawarjan"],["dc.date.accessioned","2020-12-10T15:21:43Z"],["dc.date.available","2020-12-10T15:21:43Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1016/j.wneu.2019.07.014"],["dc.identifier.issn","1878-8750"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/73130"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Test-Retest Reliability of Outpatient Telemetric Intracranial Pressure Measurements in Shunt-Dependent Patients with Hydrocephalus and Idiopathic Intracranial Hypertension"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2021Journal Article
    [["dc.bibliographiccitation.journal","Neurosurgical Review"],["dc.contributor.author","Hernández-Durán, Silvia"],["dc.contributor.author","Behme, Daniel"],["dc.contributor.author","Rohde, Veit"],["dc.contributor.author","von der Brelie, Christian"],["dc.date.accessioned","2021-08-12T07:46:11Z"],["dc.date.available","2021-08-12T07:46:11Z"],["dc.date.issued","2021"],["dc.description.abstract","Abstract The Subdural Hematoma in the Elderly (SHE) score was developed as a model to predict 30-day mortality from acute, chronic, and mixed subdural hematoma in the elderly population after minor or no trauma. Emerging evidence suggests frailty to be predictive of mortality and morbidity in the elderly. In this study, we aim to externally validate the SHE for chronic subdural hematoma (CSDH) alone, and we hypothesize that the incorporation of frailty into the SHE may increase its predictive power. A retrospective cohort of elderly patients with CSDH after minor or no trauma being treated at our institution was evaluated with the SHE. Thirty-day mortality and outcome were documented. Patients were assessed with the Clinical Frailty Scale (CFS), which was incorporated into a modified SHE (mSHE). Both the SHE and the mSHE were then assessed in their predictive powers through receiver operating characteristic statistics. We included 168 patients. Most (n = 124, 74%) had a favorable outcome at 30 days. Mortality was low at n = 7, 4%. The SHE failed to predict mortality (AUC = .564, p = .565). Contrarily, the mSHE performed well in both mortality (AUC = .749, p = .026) and outcome (AUC = .862, p < .001). A threshold of mSHE = 3 is predictive of mortality with a sensitivity of 50% and a specificity of 75% and of poor outcome with a sensitivity of 88% and a specificity of 64%. Frailty should be routinely evaluated in elderly individuals, as it can predict outcome and mortality, providing the possibility for medical, surgical, nutritional, cognitive, and physical exercise interventions."],["dc.description.abstract","Abstract The Subdural Hematoma in the Elderly (SHE) score was developed as a model to predict 30-day mortality from acute, chronic, and mixed subdural hematoma in the elderly population after minor or no trauma. Emerging evidence suggests frailty to be predictive of mortality and morbidity in the elderly. In this study, we aim to externally validate the SHE for chronic subdural hematoma (CSDH) alone, and we hypothesize that the incorporation of frailty into the SHE may increase its predictive power. A retrospective cohort of elderly patients with CSDH after minor or no trauma being treated at our institution was evaluated with the SHE. Thirty-day mortality and outcome were documented. Patients were assessed with the Clinical Frailty Scale (CFS), which was incorporated into a modified SHE (mSHE). Both the SHE and the mSHE were then assessed in their predictive powers through receiver operating characteristic statistics. We included 168 patients. Most (n = 124, 74%) had a favorable outcome at 30 days. Mortality was low at n = 7, 4%. The SHE failed to predict mortality (AUC = .564, p = .565). Contrarily, the mSHE performed well in both mortality (AUC = .749, p = .026) and outcome (AUC = .862, p < .001). A threshold of mSHE = 3 is predictive of mortality with a sensitivity of 50% and a specificity of 75% and of poor outcome with a sensitivity of 88% and a specificity of 64%. Frailty should be routinely evaluated in elderly individuals, as it can predict outcome and mortality, providing the possibility for medical, surgical, nutritional, cognitive, and physical exercise interventions."],["dc.identifier.doi","10.1007/s10143-021-01586-2"],["dc.identifier.pii","1586"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/88639"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-448"],["dc.relation.eissn","1437-2320"],["dc.relation.issn","0344-5607"],["dc.title","A matter of frailty: the modified Subdural Hematoma in the Elderly (mSHE) score"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2019Journal Article
    [["dc.bibliographiccitation.firstpage","2079"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","The American Journal of Emergency Medicine"],["dc.bibliographiccitation.lastpage","2083"],["dc.bibliographiccitation.volume","37"],["dc.contributor.author","Doukas, Alexandros"],["dc.contributor.author","Barth, Harald"],["dc.contributor.author","Petridis, K Athanasios"],["dc.contributor.author","Mehdorn, Maximilian"],["dc.contributor.author","Brelie, Christian von der"],["dc.date.accessioned","2020-04-02T13:22:13Z"],["dc.date.available","2020-04-02T13:22:13Z"],["dc.date.issued","2019"],["dc.description.abstract","Patients suffering from aneurysmatic Subarachnoid Hemorrhage (SAH) may present with a variety of symptoms. The aim of this study is to evaluate the spectrum of misdiagnoses and to analyze the significance of delay of correct diagnosis on the clinical outcome."],["dc.identifier.doi","10.1016/j.ajem.2019.03.001"],["dc.identifier.pmid","30876772"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/63535"],["dc.language.iso","en"],["dc.relation.eissn","1532-8171"],["dc.relation.issn","0735-6757"],["dc.title","Misdiagnosis of acute subarachnoid hemorrhage in the era of multimodal diagnostic options"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2017Review
    [["dc.bibliographiccitation.firstpage","1321"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","Acta Neurochirurgica"],["dc.bibliographiccitation.lastpage","1324"],["dc.bibliographiccitation.volume","159"],["dc.contributor.author","Hernandez-Duran, S."],["dc.contributor.author","Barrantes-Freer, Alonso"],["dc.contributor.author","Rohde, Veit"],["dc.contributor.author","von der Brelie, Christian"],["dc.date.accessioned","2018-11-07T10:22:12Z"],["dc.date.available","2018-11-07T10:22:12Z"],["dc.date.issued","2017"],["dc.description.abstract","Posterior reversible encephalopathy syndrome (PRES) is thought to result from endothelial dysfunction and breakdown of the blood-brain barrier with subsequent vasogenic edema. Abrupt hypertension has been identified as one of its risk factors. We present a rare case of PRES in the anterior circulation with sudden onset of left hemiparesis and rapid neurological deterioration on the basis of hypertensive crisis. Due to refractory intracranial hypertension, the patient required emergent right decompressive craniectomy. Further investigations, including a biopsy, revealed an atypical form of PRES. This case illustrates the importance of aggressive medical and early surgical management to prevent permanent neurological deficits."],["dc.identifier.doi","10.1007/s00701-017-3197-x"],["dc.identifier.isi","000403508400022"],["dc.identifier.pmid","28516363"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/42234"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Springer"],["dc.publisher.place","Wien"],["dc.relation.issn","0942-0940"],["dc.relation.issn","0001-6268"],["dc.title","Posterior reversible encephalopathy syndrome presenting in the anterior circulation with malignant intracranial hypertension requiring surgical decompression: a case report and literature review"],["dc.type","review"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2017Journal Article
    [["dc.bibliographiccitation.firstpage","101"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Acta Neurochirurgica"],["dc.bibliographiccitation.lastpage","109"],["dc.bibliographiccitation.volume","159"],["dc.contributor.author","von der Brelie, Christian"],["dc.contributor.author","Doukas, Alexandros"],["dc.contributor.author","Naumann, Rebecca"],["dc.contributor.author","Dempfle, Astrid"],["dc.contributor.author","Larsen, Naomi"],["dc.contributor.author","Synowitz, Michael"],["dc.contributor.author","Jansen, Olav"],["dc.contributor.author","Mehdorn, Maximilian"],["dc.contributor.author","Jadik, Senol"],["dc.date.accessioned","2018-11-07T10:29:10Z"],["dc.date.available","2018-11-07T10:29:10Z"],["dc.date.issued","2017"],["dc.description.abstract","Background Clinical outcome and mortality in intracerebral haemorrhage (ICH) associated with anticoagulant treatment is poor. Novel direct oral anticoagulant drugs (NOACs) are increasingly prescribed. Management of NOAC-associated ICH might be more challenging. The aim of this study was to compare the clinical and radiological course of ICH patients being treated with different forms of oral anticoagulant drugs. Method The study is a retrospective observational study. Haemorrhage in other intracranial compartments except the ventricular system were explicitly excluded. Four groups were categorised and compared with regard to their clinical and radiological course (NOACs, vitamin K antagonists [VKAs], platelet inhibitors and patients without anticoagulant/antiplatelet drugs). Clinical as well as radiological parameters were analysed. Results Overall, 182 patients were included (2011 to early 2016). Twenty-five patients with NOAC-associated ICH were included (47 with VKAs, 50 with platelet inhibitors and 60 patients without anticoagulant/antiplatelet drugs). The frequency of NOAC-associated ICH increased over the years. Diabetes was found significantly more often in the NOAC patients (p = 0.05). The clinical and radiological courses in the three different patient groups with impaired coagulation were similar. Mortality was significantly higher in patient groups with impaired coagulation (p = 0.04) compared to those without anticoagulant/antiplatelet drugs. Multivariate analysis revealed the Glasgow Coma Scale (GCS) score as a strong predictor for worse outcome and mortality. Conclusions The frequency of NOAC-associated ICH increased in the last 5 years. Diabetes might be a risk factor for ICH when receiving NOACs. Clinical outcome in NOAC-associated ICH is poor and mortality is as high as in patients with other oral anticoagulant/antiplatelet drugs."],["dc.identifier.doi","10.1007/s00701-016-3026-7"],["dc.identifier.isi","000393022000017"],["dc.identifier.pmid","27873051"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/43587"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Springer"],["dc.publisher.place","Wien"],["dc.relation.issn","0942-0940"],["dc.relation.issn","0001-6268"],["dc.title","Clinical and radiological course of intracerebral haemorrhage associated with the new non-vitamin K anticoagulants"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2020Journal Article
    [["dc.bibliographiccitation.firstpage","236"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Neurocritical Care"],["dc.bibliographiccitation.lastpage","247"],["dc.bibliographiccitation.volume","34"],["dc.contributor.author","Hernández-Durán, Silvia"],["dc.contributor.author","Salfelder, Clara"],["dc.contributor.author","Schaeper, Joern"],["dc.contributor.author","Moerer, Onnen"],["dc.contributor.author","Rohde, Veit"],["dc.contributor.author","Mielke, Dorothee"],["dc.contributor.author","von der Brelie, Christian"],["dc.date.accessioned","2021-04-14T08:26:05Z"],["dc.date.available","2021-04-14T08:26:05Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1007/s12028-020-01029-8"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/81829"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1556-0961"],["dc.relation.issn","1541-6933"],["dc.title","Mechanical Ventilation, Sedation and Neuromonitoring of Patients with Aneurysmal Subarachnoid Hemorrhage in Germany: Results of a Nationwide Survey"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2021Journal Article
    [["dc.bibliographiccitation.firstpage","e66"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Anesthesia & Analgesia"],["dc.bibliographiccitation.lastpage","e67"],["dc.bibliographiccitation.volume","133"],["dc.contributor.author","Harnisch, Lars-Olav"],["dc.contributor.author","von der Brelie, Christian"],["dc.contributor.author","Meissner, Konrad"],["dc.date.accessioned","2021-12-01T09:22:31Z"],["dc.date.available","2021-12-01T09:22:31Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.1213/ANE.0000000000005757"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/94418"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-478"],["dc.relation.issn","0003-2999"],["dc.title","Management of Severe Traumatic Brain Injury"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2021Journal Article
    [["dc.bibliographiccitation.journal","Neurosurgical Review"],["dc.contributor.author","Chacón-Quesada, T."],["dc.contributor.author","Rohde, V."],["dc.contributor.author","von der Brelie, C."],["dc.date.accessioned","2021-04-14T08:29:10Z"],["dc.date.available","2021-04-14T08:29:10Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.1007/s10143-021-01513-5"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/82818"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1437-2320"],["dc.relation.issn","0344-5607"],["dc.title","Less surgical site infections in neurosurgery during COVID-19 times—one potential benefit of the pandemic?"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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