Albrecht, Björn

[["dc.bibliographiccitation.firstpage","29"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Behavioral and Brain Functions"],["dc.bibliographiccitation.volume","4"],["dc.contributor.author","Roessner, Veit"],["dc.contributor.author","Albrecht, Björn"],["dc.contributor.author","Dechent, Peter"],["dc.contributor.author","Baudewig, Jürgen"],["dc.contributor.author","Rothenberger, Aribert"],["dc.date.accessioned","2021-06-01T10:48:00Z"],["dc.date.available","2021-06-01T10:48:00Z"],["dc.date.issued","2008"],["dc.identifier.doi","10.1186/1744-9081-4-29"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/85798"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.relation.issn","1744-9081"],["dc.title","Normal response inhibition in boys with Tourette syndrome"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","367"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Neuropsychology"],["dc.bibliographiccitation.lastpage","380"],["dc.bibliographiccitation.volume","23"],["dc.contributor.author","Marco, Rafaela"],["dc.contributor.author","Miranda, Ana"],["dc.contributor.author","Schlotz, Wolff"],["dc.contributor.author","Melia, Amanda"],["dc.contributor.author","Mulligan, Aisling"],["dc.contributor.author","Mueller, Ueli C."],["dc.contributor.author","Andreou, Penny"],["dc.contributor.author","Butler, Louise"],["dc.contributor.author","Christiansen, Hanna"],["dc.contributor.author","Gabriels, Isabel"],["dc.contributor.author","Medad, Sheera"],["dc.contributor.author","Albrecht, Bjorn"],["dc.contributor.author","Uebel, Henrik"],["dc.contributor.author","Asherson, Phillip"],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Gill, Michael"],["dc.contributor.author","Kuntsi, Jonna"],["dc.contributor.author","Mulas, Fernando"],["dc.contributor.author","Oades, Robert D."],["dc.contributor.author","Roeyers, Herbert"],["dc.contributor.author","Steinhausen, Hans-Christoph"],["dc.contributor.author","Rothenberger, Aribert"],["dc.contributor.author","Faraone, Steven V."],["dc.contributor.author","Sonuga-Barke, Edmund J."],["dc.date.accessioned","2018-11-07T08:30:30Z"],["dc.date.available","2018-11-07T08:30:30Z"],["dc.date.issued","2009"],["dc.description.abstract","Children with attention deficit/hyperactivity disorder (ADHD) choose smaller sooner (SS) over larger later (LL) rewards more than controls. Here we assess the contributions of impulsive drive for immediate rewards (IDIR) and delay aversion (DAv) to this pattern. We also explore the characteristics of, and the degree of familiality in, ADHD SS responders. We had 360 ADHD probands; 349 siblings and 112 controls (aged between 6 to 17 years) chose between SS (1 point after 2 s) and LL reward (2 points after 30 s) outcomes on the Maudsley Index of Delay Aversion (Kuntsi, Oosterlaan, & Stevenson, 2001): Under one condition SS choice led to less overall trial delay under another it did not. ADHD participants chose SS more than controls under both conditions. This effect was larger when SS choice reduced trial delay. ADHD SS responders were younger, had lower IQ, more conduct disorder and had siblings who were more likely to be SS responders themselves. The results support a dual component model in which both IDIR and DAv contribute to SS choice in ADHD. SS choice may be a marker of an ADHD motivational subtype."],["dc.description.sponsorship","NIMH [R01062873]; United Kingdom Medical Research Council [G03001896]"],["dc.identifier.doi","10.1037/a0014914"],["dc.identifier.isi","000265662000009"],["dc.identifier.pmid","19413450"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/16904"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","1931-1559"],["dc.relation.issn","0894-4105"],["dc.title","Delay and Reward Choice in ADHD: An Experimental Test of the Role of Delay Aversion"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1087"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","European Child & Adolescent Psychiatry"],["dc.bibliographiccitation.lastpage","1095"],["dc.bibliographiccitation.volume","28"],["dc.contributor.author","Aggensteiner, Pascal-M."],["dc.contributor.author","Brandeis, D."],["dc.contributor.author","Millenet, S."],["dc.contributor.author","Hohmann, S."],["dc.contributor.author","Ruckes, C."],["dc.contributor.author","Beuth, S."],["dc.contributor.author","Albrecht, B."],["dc.contributor.author","Schmitt, G."],["dc.contributor.author","Schermuly, S."],["dc.contributor.author","Wörz, S."],["dc.contributor.author","Gevensleben, H."],["dc.contributor.author","Freitag, C. M."],["dc.contributor.author","Banaschewski, T."],["dc.contributor.author","Rothenberger, A."],["dc.contributor.author","Strehl, U."],["dc.contributor.author","Holtmann, M."],["dc.date.accessioned","2020-12-10T14:11:05Z"],["dc.date.available","2020-12-10T14:11:05Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1007/s00787-018-01271-8"],["dc.identifier.eissn","1435-165X"],["dc.identifier.issn","1018-8827"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/70961"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Slow cortical potentials neurofeedback in children with ADHD: comorbidity, self-regulation and clinical outcomes 6 months after treatment in a multicenter randomized controlled trial"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","3134"],["dc.bibliographiccitation.issue","14"],["dc.bibliographiccitation.journal","Neuropsychologia"],["dc.bibliographiccitation.lastpage","3142"],["dc.bibliographiccitation.volume","47"],["dc.contributor.author","McLoughlin, Grainne"],["dc.contributor.author","Albrecht, Bjoern"],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Rothenberger, Aribert"],["dc.contributor.author","Brandeis, Daniel"],["dc.contributor.author","Asherson, Philip"],["dc.contributor.author","Kuntsi, Jonna"],["dc.date.accessioned","2018-11-07T11:21:42Z"],["dc.date.available","2018-11-07T11:21:42Z"],["dc.date.issued","2009"],["dc.description.abstract","Background: Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder that starts in childhood and frequently persists in adults. Electrophysiological studies in children with ADHD provide evidence for abnormal performance monitoring processes and familial association of these processes with ADHD. It is not yet known whether these processes show the same abnormalities and familial effects in adults. Method: We investigated event-related potential (ERP) indices of performance monitoring in adults with ADHD compared to age matched control participants. We subsequently investigated whether the ERP indices showed a familial association with ADHD by investigating these processes in first degree relatives of children with ADHD. This was achieved using an arrow flanker task presented to 21 adults with ADHD, 20 fathers of children with ADHD and 20 control participants. Results: Compared to the control group, both adults with ADHD and fathers of children with ADHD displayed significantly weaker error and conflict monitoring, as indexed by the smaller error negativity (Ne) and the N2 components. These two components were highly correlated within each of the three groups (r = 0.53-0.65). The groups did not differ on the error positivity (Pe). Conclusions: These findings closely resemble those previously found in children with ADHD, suggesting that conflict monitoring and early error processing are also abnormal in adults with ADHD; and share familial influences with ADHD throughout the lifespan. The relationship between different indices of performance monitoring may suggest partly common underlying mechanisms or modulators. (C) 2009 Elsevier Ltd. All rights reserved."],["dc.description.sponsorship","Medical Research Council [G9817803]"],["dc.identifier.doi","10.1016/j.neuropsychologia.2009.07.013"],["dc.identifier.isi","000272537900013"],["dc.identifier.pmid","19643116"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/55840"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Pergamon-elsevier Science Ltd"],["dc.relation.issn","0028-3932"],["dc.title","Performance monitoring is altered in adult ADHD: A familial event-related potential investigation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1740"],["dc.bibliographiccitation.journal","Brain"],["dc.bibliographiccitation.lastpage","1750"],["dc.bibliographiccitation.volume","134"],["dc.contributor.author","Yordanova, Juliana"],["dc.contributor.author","Albrecht, Bjoern"],["dc.contributor.author","Uebel, Henrik"],["dc.contributor.author","Kirov, Roumen"],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Rothenberger, Aribert"],["dc.contributor.author","Kolev, Vasil"],["dc.date.accessioned","2018-11-07T08:55:32Z"],["dc.date.available","2018-11-07T08:55:32Z"],["dc.date.issued","2011"],["dc.description.abstract","The maintenance of stable goal-directed behaviour is a hallmark of conscious executive control in humans. Notably, both correct and error human actions may have a subconscious activation-based determination. One possible source of subconscious interference may be the default mode network that, in contrast to attentional network, manifests intrinsic oscillations at very low (< 0.1 Hz) frequencies. In the present study, we analyse the time dynamics of performance accuracy to search for multisecond periodic fluctuations of error occurrence. Attentional lapses in attention deficit/hyperactivity disorder are proposed to originate from interferences from intrinsically oscillating networks. Identifying periodic error fluctuations with a frequency < 0.1 Hz in patients with attention deficit/hyperactivity disorder would provide a behavioural evidence for such interferences. Performance was monitored during a visual flanker task in 92 children (7- to 16-year olds), 47 with attention deficit/hyperactivity disorder, combined type and 45 healthy controls. Using an original approach, the time distribution of error occurrence was analysed in the frequency and time-frequency domains in order to detect rhythmic periodicity. Major results demonstrate that in both patients and controls, error behaviour was characterized by multisecond rhythmic fluctuations with a period of similar to 12 s, appearing with a delay after transition to task. Only in attention deficit/hyperactivity disorder, was there an additional 'pathological' oscillation of error generation, which determined periodic drops of performance accuracy each 20-30 s. Thus, in patients, periodic error fluctuations were modulated by two independent oscillatory patterns. The findings demonstrate that: (i) attentive behaviour of children is determined by multisecond regularities; and (ii) a unique additional periodicity guides performance fluctuations in patients. These observations may re-conceptualize the understanding of attentive behaviour beyond the executive top-down control and may reveal new origins of psychopathological behaviours in attention deficit/hyperactivity disorder."],["dc.identifier.doi","10.1093/brain/awr107"],["dc.identifier.isi","000291063900015"],["dc.identifier.pmid","21616970"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/22930"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press"],["dc.relation.issn","0006-8950"],["dc.title","Independent oscillatory patterns determine performance fluctuations in children with attention deficit/hyperactivity disorder"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Scientific Reports"],["dc.bibliographiccitation.volume","7"],["dc.contributor.author","Heinrich, Hartmut"],["dc.contributor.author","Grunitz, Juliane"],["dc.contributor.author","Stonawski, Valeska"],["dc.contributor.author","Frey, Stefan"],["dc.contributor.author","Wahl, Simone"],["dc.contributor.author","Albrecht, Björn"],["dc.contributor.author","Goecke, Tamme W."],["dc.contributor.author","Beckmann, Matthias W."],["dc.contributor.author","Kornhuber, Johannes"],["dc.contributor.author","Fasching, Peter A."],["dc.contributor.author","Moll, Gunther H."],["dc.contributor.author","Eichler, Anna"],["dc.date.accessioned","2019-07-09T11:43:43Z"],["dc.date.available","2019-07-09T11:43:43Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1038/s41598-017-03326-3"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14663"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/58960"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Attention, cognitive control and motivation in ADHD: Linking event-related brain potentials and DNA methylation patterns in boys at early school age"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","914"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Journal of Child Psychology and Psychiatry"],["dc.bibliographiccitation.lastpage","923"],["dc.bibliographiccitation.volume","55"],["dc.contributor.author","Albrecht, Björn"],["dc.contributor.author","Brandeis, Daniel"],["dc.contributor.author","Uebel-von Sandersleben, Henrik"],["dc.contributor.author","Valko, Lilian"],["dc.contributor.author","Heinrich, Hartmut"],["dc.contributor.author","Xu, X."],["dc.contributor.author","Drechsler, Renate"],["dc.contributor.author","Heise, Alexander"],["dc.contributor.author","Kuntsi, Jonna"],["dc.contributor.author","Mueller, Ueli C."],["dc.contributor.author","Asherson, Philip"],["dc.contributor.author","Steinhausen, Hans-Christoph"],["dc.contributor.author","Rothenberger, Aribert"],["dc.contributor.author","Banaschewski, Tobias"],["dc.date.accessioned","2018-11-07T09:37:19Z"],["dc.date.available","2018-11-07T09:37:19Z"],["dc.date.issued","2014"],["dc.description.abstract","Background: Difficulties with performance and brain activity related to attentional orienting (Cue-P3), cognitive or response preparation (Cue-CNV) and inhibitory response control (Nogo-P3) during tasks tapping executive functions are familial in ADHD and may represent endophenotypes. The aim of this study was to clarify the impact of dopamine receptor D4 (DRD4) and dopamine transporter (DAT1) gene polymorphisms on these processes in ADHD and control children. Methods: Behavioural and electrophysiological parameters from cued continuous performance tests with low and high attentional load were assessed in boys with ADHD combined type (N = 94) and controls without family history of ADHD (N = 31). Both groups were split for the presence of at least one DRD4 7-repeat allele and the DAT1 10-6 haplotype. Results: Children with ADHD showed diminished performance and lower Cue-P3, CNV and Nogo-P3 amplitudes. Children with DRD4 7R showed similar performance problems and lower Cue-P3 and CNV, but Nogo-P3 was not reduced. Children with the DAT1 10-6 haplotype had no difficulties with performance or Cue-P3 and CNV, but contrary to expectations increased Nogo-P3. There were no Genotype by ADHD interactions. Conclusions: This study detected specific effects of DRD4 7R on performance and brain activity related to attentional orienting and response preparation, while DAT1 10-6 was associated with elevated brain activity related to inhibitory response control, which potentially compensates increased impulsivity. As these genotype effects were additive to the impact of ADHD, the current results indicate that DRD4 and DAT1 polymorphisms are functionally relevant risk factors for ADHD and presumably other disorders sharing these endophenotypes."],["dc.identifier.doi","10.1111/jcpp.12212"],["dc.identifier.isi","000339384700009"],["dc.identifier.pmid","24521003"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/32815"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1469-7610"],["dc.relation.issn","0021-9630"],["dc.title","Genetics of preparation and response control in ADHD: the role of DRD4 and DAT1"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","990"],["dc.bibliographiccitation.journal","Frontiers in human neuroscience"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Gevensleben, Holger"],["dc.contributor.author","Albrecht, Björn"],["dc.contributor.author","Lütcke, Henry"],["dc.contributor.author","Auer, Tibor"],["dc.contributor.author","Dewiputri, Wan Ilma"],["dc.contributor.author","Schweizer, Renate"],["dc.contributor.author","Moll, Gunther"],["dc.contributor.author","Heinrich, Hartmut"],["dc.contributor.author","Rothenberger, Aribert"],["dc.date.accessioned","2019-07-09T11:40:54Z"],["dc.date.available","2019-07-09T11:40:54Z"],["dc.date.issued","2014"],["dc.description.abstract","To elucidate basic mechanisms underlying neurofeedback we investigated neural mechanisms of training of slow cortical potentials (SCPs) by considering EEG- and fMRI. Additionally, we analyzed the feasibility of a double-blind, placebo-controlled design in NF research based on regulation performance during treatment sessions and self-assessment of the participants. Twenty healthy adults participated in 16 sessions of SCPs training: 9 participants received regular SCP training, 11 participants received sham feedback. At three time points (pre, intermediate, post) fMRI and EEG/ERP-measurements were conducted during a continuous performance test (CPT). Performance-data during the sessions (regulation performance) in the treatment group and the placebo group were analyzed. Analysis of EEG-activity revealed in the SCP group a strong enhancement of the CNV (electrode Cz) at the intermediate assessment, followed by a decrease back to baseline at the post-treatment assessment. In contrast, in the placebo group a continuous but smaller increase of the CNV could be obtained from pre to post assessment. The increase of the CNV in the SCP group at intermediate testing was superior to the enhancement in the placebo group. The changes of the CNV were accompanied by a continuous improvement in the test performance of the CPT from pre to intermediate to post assessment comparable in both groups. The change of the CNV in the SCP group is interpreted as an indicator of neural plasticity and efficiency while an increase of the CNV in the placebo group might reflect learning and improved timing due to the frequent task repetition. In the fMRI analysis evidence was obtained for neuronal plasticity. After regular SCP neurofeedback activation in the posterior parietal cortex decreased from the pre- to the intermediate measurement and increased again in the post measurement, inversely following the U-shaped increase and decrease of the tCNV EEG amplitude in the SCP-trained group. Furthermore, we found a localized increase of activity in the anterior cingulate cortex (ACC). Analyses of the estimation of treatment assignment by the participants indicate feasibility of blinding. Participants could not assess treatment assignment confidently. Participants of the SCP-group improved regulation capability during treatment sessions (in contrast to the participants of the placebo-group), although regulation capability appeared to be instable, presumably due to diminished confidence in the training (SCP- or sham-training). Our results indicate that SCP training in healthy adults might lead to functional changes in neuronal circuits serving cognitive preparation even after a limited number of sessions."],["dc.format.extent","13"],["dc.identifier.doi","10.3389/fnhum.2014.00990"],["dc.identifier.fs","607730"],["dc.identifier.pmid","25566020"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/11462"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/58291"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","1662-5161"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Neurofeedback of slow cortical potentials: neural mechanisms and feasibility of a placebo-controlled design in healthy adults."],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1159"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","ARCHIVES OF GENERAL PSYCHIATRY"],["dc.bibliographiccitation.lastpage","1167"],["dc.bibliographiccitation.volume","67"],["dc.contributor.author","Kuntsi, Jonna"],["dc.contributor.author","Wood, Alexis C."],["dc.contributor.author","Rijsdijk, Fruehling"],["dc.contributor.author","Johnson, Katherine A."],["dc.contributor.author","Andreou, Penelope"],["dc.contributor.author","Albrecht, Bjoern"],["dc.contributor.author","Arias-Vasquez, Alejandro"],["dc.contributor.author","Buitelaar, J. K."],["dc.contributor.author","McLoughlin, Grainne"],["dc.contributor.author","Rommelse, Nanda N. J."],["dc.contributor.author","Sergeant, Joseph A."],["dc.contributor.author","Sonuga-Barke, Edmund J."],["dc.contributor.author","Uebel, Henrik"],["dc.contributor.author","van der Meere, Jaap J."],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Gill, Michael"],["dc.contributor.author","Manor, Iris"],["dc.contributor.author","Miranda, Ana"],["dc.contributor.author","Mulas, Fernando"],["dc.contributor.author","Oades, Robert D."],["dc.contributor.author","Roeyers, Herbert"],["dc.contributor.author","Rothenberger, Aribert"],["dc.contributor.author","Steinhausen, Hans-Christoph"],["dc.contributor.author","Faraone, Steven V."],["dc.contributor.author","Asherson, Philip"],["dc.date.accessioned","2018-11-07T08:37:15Z"],["dc.date.available","2018-11-07T08:37:15Z"],["dc.date.issued","2010"],["dc.description.abstract","Context: Attention-deficit/hyperactivity disorder (ADHD) is associated with widespread cognitive impairments, but it is not known whether the apparent multiple impairments share etiological roots or separate etiological pathways exist. A better understanding of the etiological pathways is important for the development of targeted interventions and for identification of suitable intermediate phenotypes for molecular genetic investigations. Objectives: To determine, by using a multivariate familial factor analysis approach, whether 1 or more familial factors underlie the slow and variable reaction times, impaired response inhibition, and choice impulsivity associated with ADHD. Design: An ADHD and control sibling-pair design. Setting: Belgium, Germany, Ireland, Israel, Spain, Switzerland, and the United Kingdom. Participants: A total of 1265 participants, aged 6 to 18 years: 464 probands with ADHD and 456 of their siblings (524 with combined-subtype ADHD), and 345 control participants. Main Outcome Measures: Performance on a 4-choice reaction time task, a go/no-go inhibition task, and a choice-delay task. Results: The final model consisted of 2 familial factors. The larger factor, reflecting 85% of the familial variance of ADHD, captured 98% to 100% of the familial influences on mean reaction time and reaction time variability. The second, smaller factor, reflecting 13% of the familial variance of ADHD, captured 62% to 82% of the familial influences on commission and omission errors on the go/no-go task. Choice impulsivity was excluded in the final model because of poor fit. Conclusions: The findings suggest the existence of 2 familial pathways to cognitive impairments in ADHD and indicate promising cognitive targets for future molecular genetic investigations. The familial distinction between the 2 cognitive impairments is consistent with recent theoretical models-a developmental model and an arousal-attention model-of 2 separable underlying processes in ADHD. Future research that tests the familial model within a developmental framework may inform developmentally sensitive interventions."],["dc.identifier.isi","000283737500012"],["dc.identifier.pmid","21041617"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/18489"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Medical Assoc"],["dc.relation.issn","1538-3636"],["dc.relation.issn","0003-990X"],["dc.title","Separation of Cognitive Impairments in Attention-Deficit/Hyperactivity Disorder Into 2 Familial Factors"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","66"],["dc.bibliographiccitation.journal","Behavioral and Brain Functions"],["dc.bibliographiccitation.volume","6"],["dc.contributor.author","McLoughlin, Grainne"],["dc.contributor.author","Albrecht, Bjoern"],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Rothenberger, Aribert"],["dc.contributor.author","Brandeis, Daniel"],["dc.contributor.author","Asherson, Philip"],["dc.contributor.author","Kuntsi, Jonna"],["dc.date.accessioned","2018-11-07T08:37:53Z"],["dc.date.available","2018-11-07T08:37:53Z"],["dc.date.issued","2010"],["dc.description.abstract","Background: Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder that starts in childhood and frequently persists in adults. Several theories postulate deficits in ADHD that have effects across many executive functions or in more narrowly defined aspects, such as response inhibition. Electrophysiological studies on children, however, indicate that ADHD is not associated with a core deficit of response inhibition, as abnormal inhibitory processing is typically preceded or accompanied by other processing deficits. It is not yet known if this pattern of abnormal processing is evident in adult ADHD. Methods: The objective of this paper was to investigate event-related potential indices of preparatory states and subsequent response inhibition processing in adults with ADHD. Two cued continuous performance tasks were presented to 21 adults meeting current criteria for adult ADHD and combined type ADHD in childhood, and 20 controls. Results: The ADHD group exhibited significantly weaker orienting attention to cues, cognitive preparation processes and inhibitory processing. In addition, we observed a strong correlation between the resources allocated to orienting to cues and the strength of the subsequent response strength control processes, suggesting that orienting deficits partly predict and determine response control deficits in ADHD. Conclusions: These findings closely resemble those previously found in children with ADHD, which indicate that there is not a core response inhibition deficit in ADHD. These findings therefore suggest the possibility of developmental stability into adulthood of the underlying abnormal processes in ADHD."],["dc.description.sponsorship","Janssen-Cilag"],["dc.identifier.doi","10.1186/1744-9081-6-66"],["dc.identifier.isi","000284397100001"],["dc.identifier.pmid","21029446"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/18650"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Biomed Central Ltd"],["dc.relation.issn","1744-9081"],["dc.title","Electrophysiological evidence for abnormal preparatory states and inhibitory processing in adult ADHD"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]