Now showing 1 - 8 of 8
  • 2015Journal Article
    [["dc.bibliographiccitation.artnumber","016002"],["dc.bibliographiccitation.firstpage","1"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Journal of Neural Engineering"],["dc.bibliographiccitation.lastpage","15"],["dc.bibliographiccitation.volume","13"],["dc.contributor.author","Morel, Pierre"],["dc.contributor.author","Ferrea, Enrico"],["dc.contributor.author","Taghizadeh-Sarshouri, Bahareh"],["dc.contributor.author","Audí, Josep Marcel Cardona"],["dc.contributor.author","Ruff, Roman"],["dc.contributor.author","Hoffmann, Klaus-Peter"],["dc.contributor.author","Lewis, Sören"],["dc.contributor.author","Russold, Michael"],["dc.contributor.author","Dietl, Hans"],["dc.contributor.author","Abu-Saleh, Lait"],["dc.contributor.author","Schroeder, Dietmar"],["dc.contributor.author","Krautschneider, Wolfgang"],["dc.contributor.author","Meiners, Thomas"],["dc.contributor.author","Gail, Alexander"],["dc.date.accessioned","2017-09-07T11:47:44Z"],["dc.date.available","2017-09-07T11:47:44Z"],["dc.date.issued","2015"],["dc.description.abstract","OBJECTIVE:The ease of use and number of degrees of freedom of current myoelectric hand prostheses is limited by the information content and reliability of the surface electromyography (sEMG) signals used to control them. For example, cross-talk limits the capacity to pick up signals from small or deep muscles, such as the forearm muscles for distal arm amputations, or sites of targeted muscle reinnervation (TMR) for proximal amputations. Here we test if signals recorded from the fully implanted, induction-powered wireless Myoplant system allow long-term decoding of continuous as well as discrete movement parameters with better reliability than equivalent sEMG recordings. The Myoplant system uses a centralized implant to transmit broadband EMG activity from four distributed bipolar epimysial electrodes.APPROACH:Two Rhesus macaques received implants in their backs, while electrodes were placed in their upper arm. One of the monkeys was trained to do a cursor task via a haptic robot, allowing us to control the forces exerted by the animal during arm movements. The second animal was trained to perform a center-out reaching task on a touchscreen. We compared the implanted system with concurrent sEMG recordings by evaluating our ability to decode time-varying force in one animal and discrete reach directions in the other from multiple features extracted from the raw EMG signals.MAIN RESULTS:In both cases, data from the implant allowed a decoder trained with data from a single day to maintain an accurate decoding performance during the following months, which was not the case for concurrent surface EMG recordings conducted simultaneously over the same muscles.SIGNIFICANCE:These results show that a fully implantable, centralized wireless EMG system is particularly suited for long-term stable decoding of dynamic movements in demanding applications such as advanced forelimb prosthetics in a wide range of configurations (distal amputations, TMR)."],["dc.identifier.doi","10.1088/1741-2560/13/1/016002"],["dc.identifier.gro","3150711"],["dc.identifier.pmid","26643959"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14153"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/7498"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","final"],["dc.relation.issn","1741-2560"],["dc.rights","CC BY 3.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/3.0"],["dc.title","Long-term decoding of movement force and direction with a wireless myoelectric implant"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.peerReviewed","no"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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  • 2014Journal Article
    [["dc.bibliographiccitation.artnumber","A119"],["dc.bibliographiccitation.journal","Astronomy & Astrophysics"],["dc.bibliographiccitation.volume","564"],["dc.contributor.author","Morel, T."],["dc.contributor.author","Miglio, A."],["dc.contributor.author","Lagarde, N."],["dc.contributor.author","Montalbán, J."],["dc.contributor.author","Rainer, M."],["dc.contributor.author","Poretti, E."],["dc.contributor.author","Eggenberger, P."],["dc.contributor.author","Hekker, S."],["dc.contributor.author","Kallinger, T."],["dc.contributor.author","Mosser, B."],["dc.contributor.author","Valentini, M."],["dc.contributor.author","Carrier, F."],["dc.contributor.author","Hareter, M."],["dc.contributor.author","Mantegazza, L."],["dc.date.accessioned","2019-07-09T11:40:19Z"],["dc.date.available","2019-07-09T11:40:19Z"],["dc.date.issued","2014"],["dc.description.abstract","A precise characterisation of the red giants in the seismology fields of the CoRoT satellite is a prerequisite for further in-depth seismic modelling. High-resolution FEROS and HARPS spectra were obtained as part of the ground-based follow-up campaigns for 19 targets holding great asteroseismic potential. These data are used to accurately estimate their fundamental parameters and the abundances of 16 chemical species in a self-consistent manner. Some powerful probes of mixing are investigated (the Li and CNO abundances, as well as the carbon isotopic ratio in a few cases). The information provided by the spectroscopic and seismic data is combined to provide more accurate physical parameters and abundances. The stars in our sample follow the general abundance trends as a function of the metallicity observed in stars of the Galactic disk. After an allowance is made for the chemical evolution of the interstellar medium, the observational signature of internal mixing phenomena is revealed through the detection at the stellar surface of the products of the CN cycle. A contamination by NeNa-cycled material in the most massive stars is also discussed. With the asteroseismic constraints, these data will pave the way for a detailed theoretical investigation of the physical processes responsible for the transport of chemical elements in evolved, low- and intermediate-mass stars."],["dc.format.extent","20"],["dc.identifier.doi","10.1051/0004-6361/201322810"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/10919"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/58146"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation","info:eu-repo/grantAgreement/EC/FP7/338251/EU//STELLARAGES"],["dc.relation.euproject","Stellar Ages"],["dc.relation.issn","1432-0746"],["dc.relation.orgunit","Fakultät für Physik"],["dc.title","Atmospheric parameters and chemical properties of red giants in the CoRoT asteroseismology fields"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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  • 2022Journal Article
    [["dc.bibliographiccitation.artnumber","e726"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","HemaSphere"],["dc.bibliographiccitation.volume","6"],["dc.contributor.author","Dreyling, Martin"],["dc.contributor.author","André, Marc"],["dc.contributor.author","Gökbuget, Nicola"],["dc.contributor.author","Tilly, Hervé"],["dc.contributor.author","Jerkeman, Mats"],["dc.contributor.author","Gribben, John"],["dc.contributor.author","Ferreri, Andrés"],["dc.contributor.author","Morel, Pierre"],["dc.contributor.author","Stilgenbauer, Stephan"],["dc.contributor.author","Fox, Christopher"],["dc.contributor.author","Salles, Gilles"],["dc.date.accessioned","2022-06-01T09:39:24Z"],["dc.date.available","2022-06-01T09:39:24Z"],["dc.date.issued","2022"],["dc.identifier.doi","10.1097/HS9.0000000000000726"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/108465"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-572"],["dc.relation.eissn","2572-9241"],["dc.title","The EHA Research Roadmap: Malignant Lymphoid Diseases"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2022Journal Article
    [["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Scientific Reports"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Ferrea, E."],["dc.contributor.author","Franke, J."],["dc.contributor.author","Morel, P."],["dc.contributor.author","Gail, A."],["dc.date.accessioned","2022-07-01T07:34:52Z"],["dc.date.available","2022-07-01T07:34:52Z"],["dc.date.issued","2022"],["dc.description.abstract","Abstract Neurorehabilitation in patients suffering from motor deficits relies on relearning or re-adapting motor skills. Yet our understanding of motor learning is based mostly on results from one or two-dimensional experimental paradigms with highly confined movements. Since everyday movements are conducted in three-dimensional space, it is important to further our understanding about the effect that gravitational forces or perceptual anisotropy might or might not have on motor learning along all different dimensions relative to the body. Here we test how well existing concepts of motor learning generalize to movements in 3D. We ask how a subject’s variability in movement planning and sensory perception influences motor adaptation along three different body axes. To extract variability and relate it to adaptation rate, we employed a novel hierarchical two-state space model using Bayesian modeling via Hamiltonian Monte Carlo procedures. Our results show that differences in adaptation rate occur between the coronal, sagittal and horizontal planes and can be explained by the Kalman gain, i.e., a statistically optimal solution integrating planning and sensory information weighted by the inverse of their variability. This indicates that optimal integration theory for error correction holds for 3D movements and explains adaptation rate variation between movements in different planes."],["dc.description.sponsorship"," Deutsche Forschungsgemeinschaft http://dx.doi.org/10.13039/501100001659"],["dc.description.sponsorship","Federal Ministry for Education and Research, Germany"],["dc.description.sponsorship","Deutsches Primatenzentrum GmbH - Leibniz-Institut für Primatenforschung"],["dc.identifier.doi","10.1038/s41598-022-13866-y"],["dc.identifier.pii","13866"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/112030"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-581"],["dc.relation.eissn","2045-2322"],["dc.relation.haserratum","/handle/2/113626"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Statistical determinants of visuomotor adaptation along different dimensions during naturalistic 3D reaches"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2017Journal Article
    [["dc.bibliographiccitation.artnumber","e2001323"],["dc.bibliographiccitation.firstpage","1"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","PLoS Biology"],["dc.bibliographiccitation.lastpage","23"],["dc.bibliographiccitation.volume","15"],["dc.contributor.author","Morel, Pierre"],["dc.contributor.author","Ulbrich, Philipp"],["dc.contributor.author","Gail, Alexander"],["dc.date.accessioned","2017-09-07T11:47:47Z"],["dc.date.available","2017-09-07T11:47:47Z"],["dc.date.issued","2017"],["dc.description.abstract","When deciding between alternative options, a rational agent chooses on the basis of the desirability of each outcome, including associated costs. As different options typically result in different actions, the effort associated with each action is an essential cost parameter. How do humans discount physical effort when deciding between movements? We used an action-selection task to characterize how subjective effort depends on the parameters of arm transport movements and controlled for potential confounding factors such as delay discounting and performance. First, by repeatedly asking subjects to choose between 2 arm movements of different amplitudes or durations, performed against different levels of force, we identified parameter combinations that subjects experienced as identical in effort (isoeffort curves). Movements with a long duration were judged more effortful than short-duration movements against the same force, while movement amplitudes did not influence effort. Biomechanics of the movements also affected effort, as movements towards the body midline were preferred to movements away from it. Second, by introducing movement repetitions, we further determined that the cost function for choosing between effortful movements had a quadratic relationship with force, while choices were made on the basis of the logarithm of these costs. Our results show that effort-based action selection during reaching cannot easily be explained by metabolic costs. Instead, force-loaded reaches, a widely occurring natural behavior, imposed an effort cost for decision making similar to cost functions in motor control. Our results thereby support the idea that motor control and economic choice are governed by partly overlapping optimization principles."],["dc.identifier.doi","10.1371/journal.pbio.2001323"],["dc.identifier.gro","3150720"],["dc.identifier.pmid","28586347"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14559"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/7507"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","final"],["dc.relation.issn","1545-7885"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","What makes a reach movement effortful? Physical effort discounting supports common minimization principles in decision making and motor control"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","no"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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  • 2022Journal Article Erratum
    [["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Scientific Reports"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Ferrea, E."],["dc.contributor.author","Franke, J."],["dc.contributor.author","Morel, P."],["dc.contributor.author","Gail, A."],["dc.date.accessioned","2022-09-01T09:50:07Z"],["dc.date.available","2022-09-01T09:50:07Z"],["dc.date.issued","2022"],["dc.identifier.doi","10.1038/s41598-022-16148-9"],["dc.identifier.pii","16148"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/113626"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-597"],["dc.relation.eissn","2045-2322"],["dc.relation.iserratumof","/handle/2/112030"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Author Correction: Statistical determinants of visuomotor adaptation along different dimensions during naturalistic 3D reaches"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","erratum_ja"],["dspace.entity.type","Publication"]]
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  • 2013Journal Article
    [["dc.bibliographiccitation.artnumber","A74"],["dc.bibliographiccitation.journal","Astronomy and Astrophysics"],["dc.bibliographiccitation.volume","549"],["dc.contributor.author","Marques, J. P."],["dc.contributor.author","Goupil, M. J."],["dc.contributor.author","Lebreton, Yveline"],["dc.contributor.author","Talon, S."],["dc.contributor.author","Palacios, A."],["dc.contributor.author","Belkacem, K."],["dc.contributor.author","Ouazzani, R.-M."],["dc.contributor.author","Mosser, B."],["dc.contributor.author","Moya, A."],["dc.contributor.author","Morel, P."],["dc.contributor.author","Pichon, B."],["dc.contributor.author","Mathis, S."],["dc.contributor.author","Zahn, J.-P."],["dc.contributor.author","Turck-Chieze, S."],["dc.contributor.author","Nghiem, P. A. P."],["dc.date.accessioned","2018-11-07T09:30:35Z"],["dc.date.available","2018-11-07T09:30:35Z"],["dc.date.issued","2013"],["dc.description.abstract","Context. Rotational splittings are currently measured for several main sequence stars and a large number of red giants with the space mission Kepler. This will provide stringent constraints on rotation profiles. Aims. Our aim is to obtain seismic constraints on the internal transport and surface loss of the angular momentum of oscillating solar-like stars. To this end, we study the evolution of rotational splittings from the pre-main sequence to the red-giant branch for stochastically excited oscillation modes. Methods. We modified the evolutionary code CESAM2K to take rotationally induced transport in radiative zones into account. Linear rotational splittings were computed for a sequence of 1.3 M-circle dot models. Rotation profiles were derived from our evolutionary models and eigenfunctions from linear adiabatic oscillation calculations. Results. We find that transport by meridional circulation and shear turbulence yields far too high a core rotation rate for red-giant models compared with recent seismic observations. We discuss several uncertainties in the physical description of stars that could have an impact on the rotation profiles. For instance, we find that the Goldreich-Schubert-Fricke instability does not extract enough angular momentum from the core to account for the discrepancy. In contrast, an increase of the horizontal turbulent viscosity by 2 orders of magnitude is able to significantly decrease the central rotation rate on the red-giant branch. Conclusions. Our results indicate that it is possible that the prescription for the horizontal turbulent viscosity largely underestimates its actual value or else a mechanism not included in current stellar models of low mass stars is needed to slow down the rotation in the radiative core of red-giant stars."],["dc.identifier.doi","10.1051/0004-6361/201220211"],["dc.identifier.isi","000313745000074"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/9963"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/31337"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Edp Sciences S A"],["dc.relation.issn","0004-6361"],["dc.relation.orgunit","Fakultät für Physik"],["dc.title","Seismic diagnostics for transport of angular momentum in stars I. Rotational splittings from the pre-main sequence to the red-giant branch"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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  • 2015Journal Article
    [["dc.bibliographiccitation.artnumber","bhu312"],["dc.bibliographiccitation.firstpage","731"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Cerebral Cortex"],["dc.bibliographiccitation.lastpage","741"],["dc.bibliographiccitation.volume","26"],["dc.contributor.author","Kuang, Shenbing"],["dc.contributor.author","Morel, Pierre"],["dc.contributor.author","Gail, Alexander"],["dc.date.accessioned","2017-09-07T11:47:44Z"],["dc.date.available","2017-09-07T11:47:44Z"],["dc.date.issued","2015"],["dc.description.abstract","Neurons in the posterior parietal cortex respond selectively for spatial parameters of planned goal-directed movements. Yet, it is still unclear which aspects of the movement the neurons encode: the spatial parameters of the upcoming physical movement (physical goal), or the upcoming visual limb movement (visual goal). To test this, we recorded neuronal activity from the parietal reach region while monkeys planned reaches under either normal or prism-reversed viewing conditions. We found predominant encoding of physical goals while fewer neurons were selective for visual goals during planning. In contrast, local field potentials recorded in the same brain region exhibited predominant visual goal encoding, similar to previous imaging data from humans. The visual goal encoding in individual neurons was neither related to immediate visual input nor to visual memory, but to the future visual movement. Our finding suggests that action planning in parietal cortex is not exclusively a precursor of impending physical movements, as reflected by the predominant physical goal encoding, but also contains spatial kinematic parameters of upcoming visual movement, as reflected by co-existing visual goal encoding in neuronal spiking. The co-existence of visual and physical goals adds a complementary perspective to the current understanding of parietal spatial computations in primates."],["dc.identifier.doi","10.1093/cercor/bhu312"],["dc.identifier.gro","3150714"],["dc.identifier.pmid","25576535"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/7501"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.issn","1047-3211"],["dc.title","Planning Movements in Visual and Physical Space in Monkey Posterior Parietal Cortex"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.peerReviewed","no"],["dspace.entity.type","Publication"]]
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