Buckow, Karoline

[["dc.bibliographiccitation.firstpage","461"],["dc.bibliographiccitation.journal","Multiple Sclerosis Journal"],["dc.bibliographiccitation.lastpage","462"],["dc.bibliographiccitation.volume","22"],["dc.contributor.author","Meissner, Thomas"],["dc.contributor.author","Ellenberger, David"],["dc.contributor.author","Flachenecker, Peter"],["dc.contributor.author","Hillert, Jan"],["dc.contributor.author","Buckow, Karoline"],["dc.date.accessioned","2018-11-07T10:08:50Z"],["dc.date.available","2018-11-07T10:08:50Z"],["dc.date.issued","2016"],["dc.identifier.isi","000383267202113"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/39544"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Sage Publications Ltd"],["dc.publisher.place","London"],["dc.relation.conference","32nd Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS)"],["dc.relation.eventlocation","London, ENGLAND"],["dc.relation.issn","1477-0970"],["dc.relation.issn","1352-4585"],["dc.title","Differences in employment of people with MS across Europe"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","587"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","European Journal of Clinical Investigation"],["dc.bibliographiccitation.lastpage","593"],["dc.bibliographiccitation.volume","45"],["dc.contributor.author","Rommer, Paulus S."],["dc.contributor.author","Buckow, Karoline"],["dc.contributor.author","Ellenberger, David"],["dc.contributor.author","Friede, Tim"],["dc.contributor.author","Pitschnau-Michel, Dorothea"],["dc.contributor.author","Fuge, Jan"],["dc.contributor.author","Stueve, Olaf"],["dc.contributor.author","Zettl, Uwe K."],["dc.date.accessioned","2018-11-07T09:56:47Z"],["dc.date.available","2018-11-07T09:56:47Z"],["dc.date.issued","2015"],["dc.description.abstract","BackgroundMultiple Sclerosis is the most common disease in young adults affecting the central nervous system. Disease may progress with acute attacks (relapsing MS) or continuously (progressive MS). Glucocorticosteroids are used in the treatment of acute attacks. The aim of this study was to analyse characteristics of patients with MS, and their influence on current treatment patterns of relapses with glucocorticosteroids. DesignIn 2001, the German National MS Society initiated the German MS-Registry. Patients with relapsing MS were included (n=5106) from this registry. Logistic regression models were used to detect trends over time. The likelihood of administration of steroids is modelled in dependence of calendar year and in dependence to confounders in treatment conditions. The sample size allows that odds ratios can be detected with a power of 90% (alpha=005). ResultsAdministration of glucocorticosteroids was influenced by EDSS (P<00001), age (P<00001) and disease duration (P<00001). Therapy administration in an outpatient setting was more likely in patients with higher EDSS (P<00001) and longer disease duration (P<00001). The utilization of glucocorticosteroids increased with higher EDSS for all relapsing patients. Interestingly, all overutilization of glucocorticosteroids decreased over time and was accompanied by a steadily increased administration of emergent therapeutics. Although there are about 70% of registered patients with relapsing MS on immune-modulatory treatment, almost 60% of them received glucocorticosteroids for treatment of relapses. ConclusionsTreatment patterns with glucocorticosteroids in patients with MS are influenced mainly by EDSS and disease duration. The decline in the utilization of glucocorticosteroids is accompanied by an increase in natalizumab treatment."],["dc.description.sponsorship","Teva Pharmaceuticals"],["dc.identifier.doi","10.1111/eci.12450"],["dc.identifier.isi","000354645200007"],["dc.identifier.pmid","25868705"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/37036"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1365-2362"],["dc.relation.issn","0014-2972"],["dc.title","Patients characteristics influencing the longitudinal utilization of steroids in multiple sclerosis - an observational study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1"],["dc.bibliographiccitation.issue","doc10gmds308"],["dc.bibliographiccitation.journal","GMS Medizinische Informatik, Biometrie und Epidemiologie"],["dc.bibliographiccitation.lastpage","9"],["dc.contributor.author","Antony, Gisela"],["dc.contributor.author","Buckow, Karoline"],["dc.contributor.author","Khil, Laura"],["dc.contributor.author","Stroet, Anke"],["dc.date.accessioned","2019-07-10T08:13:52Z"],["dc.date.available","2019-07-10T08:13:52Z"],["dc.date.issued","2010"],["dc.identifier.fs","576573"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/7568"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/61359"],["dc.language.iso","de"],["dc.notes.intern","Merged from goescholar"],["dc.relation.orgunit","Universitätsmedizin Göttingen"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.subject.ddc","610"],["dc.title","Entwicklung eines gemeinsamen modularen Datensatzes für die Studien des KKNMS und der DMSG"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","7"],["dc.bibliographiccitation.issue","01"],["dc.bibliographiccitation.journal","Aktuelle Neurologie"],["dc.bibliographiccitation.lastpage","23"],["dc.bibliographiccitation.volume","45"],["dc.contributor.author","Thiel, Sandra"],["dc.contributor.author","Leypoldt, Frank"],["dc.contributor.author","Röpke, Luise"],["dc.contributor.author","Wandinger, Klaus"],["dc.contributor.author","Kümpfel, Tania"],["dc.contributor.author","Aktas, Orhan"],["dc.contributor.author","von Bismarck, Olga"],["dc.contributor.author","Salmen, Anke"],["dc.contributor.author","Ambrosius, Björn"],["dc.contributor.author","Ellrichmann, Gisa"],["dc.contributor.author","Antony, Gisela"],["dc.contributor.author","Dankowski, Theresa"],["dc.contributor.author","Ziegler, Andreas"],["dc.contributor.author","Stahmann, Alexander"],["dc.contributor.author","Meyer, Carola"],["dc.contributor.author","Eichstädt, Kerstin"],["dc.contributor.author","Buckow, Karoline"],["dc.contributor.author","Meißner, Tina"],["dc.contributor.author","Thibaut, Jasmine"],["dc.contributor.author","Khil, Laura"],["dc.contributor.author","Berger, Klaus"],["dc.contributor.author","Gold, Ralf"],["dc.contributor.author","Hellwig, Kerstin"],["dc.date.accessioned","2020-12-10T18:12:24Z"],["dc.date.available","2020-12-10T18:12:24Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1055/s-0043-108909"],["dc.identifier.eissn","1438-9428"],["dc.identifier.issn","0302-4350"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/74360"],["dc.language.iso","de"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Neuroimmunologische Register in Deutschland"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","589"],["dc.bibliographiccitation.journal","Multiple Sclerosis Journal"],["dc.bibliographiccitation.lastpage","590"],["dc.bibliographiccitation.volume","22"],["dc.contributor.author","Stahmann, Alexander"],["dc.contributor.author","Buckow, Karoline"],["dc.contributor.author","Ellenberger, David"],["dc.contributor.author","Heymann, D."],["dc.contributor.author","Mai, M."],["dc.contributor.author","Meissner, Thomas"],["dc.contributor.author","Zettl, Uwe K."],["dc.date.accessioned","2018-11-07T10:08:50Z"],["dc.date.available","2018-11-07T10:08:50Z"],["dc.date.issued","2016"],["dc.description.sponsorship","Merck Serono; Biogen Idec; Bayer; Genzyme; Novartis; TEVA Sanofi"],["dc.identifier.isi","000383267202338"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/39545"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Sage Publications Ltd"],["dc.publisher.place","London"],["dc.relation.conference","32nd Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS)"],["dc.relation.eventlocation","London, ENGLAND"],["dc.relation.issn","1477-0970"],["dc.relation.issn","1352-4585"],["dc.title","The German MS Register: update on immunotherapy"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","24"],["dc.bibliographiccitation.journal","Acta Neurologica Scandinavica"],["dc.bibliographiccitation.lastpage","30"],["dc.bibliographiccitation.volume","126"],["dc.contributor.author","Pugliatti, Maura"],["dc.contributor.author","Eskic, Danica"],["dc.contributor.author","Mikolcic, T."],["dc.contributor.author","Pitschnau-Michel, Dorothea"],["dc.contributor.author","Myhr, K.-M."],["dc.contributor.author","Sastre-Garriga, Jaume"],["dc.contributor.author","Otero, Susana"],["dc.contributor.author","Wieczynska, L."],["dc.contributor.author","Torje, C."],["dc.contributor.author","Holloway, Edward"],["dc.contributor.author","Rienhoff, Otto"],["dc.contributor.author","Friede, Tim"],["dc.contributor.author","Buckow, Karoline"],["dc.contributor.author","Ellenberger, David"],["dc.contributor.author","Hillert, Jan"],["dc.contributor.author","Glaser, Anna"],["dc.contributor.author","Flachenecker, Peter"],["dc.contributor.author","Fuge, Jan"],["dc.contributor.author","Schyns-Liharska, Tsveta"],["dc.contributor.author","Kasilingam, E."],["dc.contributor.author","Moretti, A."],["dc.contributor.author","Thalheim, Christoph"],["dc.date.accessioned","2018-11-07T09:02:24Z"],["dc.date.available","2018-11-07T09:02:24Z"],["dc.date.issued","2012"],["dc.description.abstract","Objectives - Persons with multiple sclerosis (PwMS) experience health-related quality of life (HRQoL) problems greatly differing across Europe, and the European Union (EU) faces deep inequalities in MS management from country to country. Through the establishment of a European MS Register (EUReMS), an effective action is proposed to improve the overall knowledge on MS and support effective intervention programmes at EU and national political level. EUReMS aims to achieve consensus on its mission and vision, to define existing data providers, to develop models driving future MS health policies and research, to develop an information technology (IT) infrastructure for a data set, to develop a European shared governance and to secure providers' data provision into EUReMS. Materials and methods - EUReMS is meant to build on a minimum set of core data from existing national and regional population-based MS registries and from PwMS' perspectives. EUReMS' main partner is the European MS Platform (EMSP) acting in collaboration with associated and collaborating European partners. Results - EUReMS was launched in July 2011. A Consensus Statement on purposes, vision, mission and strategies was produced in December 2011, and a comprehensive survey on existing MS data collections in Europe has been performed, and the EUReMS data mask is currently being discussed. Conclusions - EUReMS will represent a tool to provide up to date, comparable and sustainable MS data through an effective and credible register, which will encourage extensive knowledge building of MS, more equitable policies and higher standards in MS treatment and services."],["dc.identifier.doi","10.1111/ane.12024"],["dc.identifier.isi","000316128600006"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/24677"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","0001-6314"],["dc.title","Assess, compare and enhance the status of Persons with Multiple Sclerosis (MS) in Europe: a European Register for MS"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1523"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Multiple Sclerosis Journal"],["dc.bibliographiccitation.lastpage","1532"],["dc.bibliographiccitation.volume","20"],["dc.contributor.author","Flachenecker, Peter"],["dc.contributor.author","Buckow, Karoline"],["dc.contributor.author","Pugliatti, Maura"],["dc.contributor.author","Kes, Vanja Basic"],["dc.contributor.author","Battaglia, Mario A."],["dc.contributor.author","Boyko, Alexey"],["dc.contributor.author","Confavreux, Christian"],["dc.contributor.author","Ellenberger, David"],["dc.contributor.author","Eskic, Danica"],["dc.contributor.author","Ford, David"],["dc.contributor.author","Friede, Tim"],["dc.contributor.author","Fuge, Jan"],["dc.contributor.author","Glaser, Anna"],["dc.contributor.author","Hillert, Jan"],["dc.contributor.author","Holloway, Edward"],["dc.contributor.author","Ioannidou, Eva"],["dc.contributor.author","Kappos, Ludwig"],["dc.contributor.author","Kasilingam, Elisabeth"],["dc.contributor.author","Koch-Henriksen, Nils"],["dc.contributor.author","Kuhle, Jens"],["dc.contributor.author","Lepore, Vito"],["dc.contributor.author","Middleton, Rod"],["dc.contributor.author","Myhr, Kjell-Morton"],["dc.contributor.author","Orologas, Anastasios"],["dc.contributor.author","Otero, Susana"],["dc.contributor.author","Pitschnau-Michel, Dorothea"],["dc.contributor.author","Rienhoff, Otto"],["dc.contributor.author","Sastre-Garriga, Jaume"],["dc.contributor.author","Schyns-Liharska, Tsveta"],["dc.contributor.author","Sutovic, Dragana"],["dc.contributor.author","Thalheim, Christoph"],["dc.contributor.author","Trojano, Maria"],["dc.contributor.author","Vlasov, Yan V."],["dc.contributor.author","Yaldizli, Oezguer"],["dc.date.accessioned","2018-11-07T09:34:24Z"],["dc.date.available","2018-11-07T09:34:24Z"],["dc.date.issued","2014"],["dc.description.abstract","Background: Identification of MS registries and databases that are currently in use in Europe as well as a detailed knowledge of their content and structure is important in order to facilitate comprehensive analysis and comparison of data. Methods: National MS registries or databases were identified by literature search, from the results of the MS Barometer 2011 and by asking 33 national MS societies. A standardized questionnaire was developed and sent to the registries' leaders, followed by telephone interviews with them. Results: Twenty registries were identified, with 13 completing the questionnaire and seven being interviewed by telephone. These registries differed widely for objectives, structure, collected data, and for patients and centres included. Despite this heterogeneity, common objectives of the registries were epidemiology (n=10), long-term therapy outcome (n=8), healthcare research (n=9) and support/basis for clinical trials (n=8). While physician-based outcome measures (EDSS) are used in all registries, data from patients' perspectives were only collected in six registries. Conclusions: The detailed information on a large number of national MS registries in Europe is a prerequisite to facilitating harmonized integration of existing data from MS registries and databases, as well as comprehensive analyses and comparison across European populations."],["dc.identifier.doi","10.1177/1352458514528760"],["dc.identifier.isi","000343623900016"],["dc.identifier.pmid","24777278"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/12994"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/32165"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Sage Publications Ltd"],["dc.relation.issn","1477-0970"],["dc.relation.issn","1352-4585"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Multiple sclerosis registries in Europe - results of a systematic survey"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","22"],["dc.bibliographiccitation.journal","Neuroscience Research"],["dc.bibliographiccitation.lastpage","28"],["dc.bibliographiccitation.volume","102"],["dc.contributor.author","Buckow, Karoline"],["dc.contributor.author","Quade, Matthias"],["dc.contributor.author","Rienhoff, Otto"],["dc.contributor.author","Nussbeck, Sara Y."],["dc.date.accessioned","2018-11-07T10:21:02Z"],["dc.date.available","2018-11-07T10:21:02Z"],["dc.date.issued","2016"],["dc.description.abstract","The observation of growing \"difficulties\" in IT-infrastructures in neuroscience research during the last years led to a search for reasons and an analysis on how this phenomenon is reflected in the scientific literature. With a retrospective analysis of nine examples of multicenter research projects in the neurosciences and a literature review the observation was systematically analyzed. Results show that the rise in complexity mainly stems from two reasons: (1) more and more need for information on quality and context of research data (metadata) and (2) long-term requirements to handle the consent and identity/pseudonyms of study participants and biomaterials in relation to legal requirements. The combination of these two aspects together with very long study times and data evaluation periods are components of the subjectively perceived \"difficulties\". A direct consequence of this result is that big multicenter trials are becoming part of integrated research data environments and are not standing alone for themselves anymore. This drives up the resource needs regarding the IT-infrastructure in neuroscience research. In contrast to these findings, literature on this development is scarce and the problem probably underestimated. (C) 2014 Elsevier Ireland Ltd and the Japan Neuroscience Society. All rights reserved."],["dc.identifier.doi","10.1016/j.neures.2014.08.005"],["dc.identifier.isi","000370180400004"],["dc.identifier.pmid","25152316"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/42008"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Ireland Ltd"],["dc.relation.issn","1872-8111"],["dc.relation.issn","0168-0102"],["dc.title","Changing requirements and resulting needs for IT-infrastructure for longitudinal research in the neurosciences"],["dc.type","review"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","409"],["dc.bibliographiccitation.journal","Multiple Sclerosis Journal"],["dc.bibliographiccitation.lastpage","410"],["dc.bibliographiccitation.volume","20"],["dc.contributor.author","Flachenecker, Peter"],["dc.contributor.author","Buckow, Karoline"],["dc.date.accessioned","2018-11-07T09:35:29Z"],["dc.date.available","2018-11-07T09:35:29Z"],["dc.date.issued","2014"],["dc.identifier.isi","000354441300941"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/32392"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Sage Publications Ltd"],["dc.publisher.place","London"],["dc.relation.conference","Joint ACTRIMS-ECTRIMS Meeting"],["dc.relation.eventlocation","Boston, MA"],["dc.relation.issn","1477-0970"],["dc.relation.issn","1352-4585"],["dc.title","Assessment of the patient's perspective in the European Register for Multiple Sclerosis (EUReMS): study protocol of the PRO study"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]